Clinical trials: in Bahrain
Osteoarthritis
Intraarticular Platelet-rich Plasma Injections Versus Corticosteroid Injections in Primary Knee Osteoarthritis
Aim: To study and compare the clinical effects of platelet-rich plasma (PRP) injections and intra-articular (IA) corticosteroid injections in patients with primary osteoarthritis (OA) of the knee.
- Trial name
- NCT01923909
- Testing
- Intra-articular platelet-rich plasma, Intra-articular corticosteroid injections
- Where
- Bahrain
- Sponsor
- King Hamad University Hospital, Bahrain
Airway Obstruction
The Incidence of Difficult Intubation in Obese Versus Non-obese Patients
The aim of our study is to identify the incidence of difficult endotracheal intubation in patients with normal BMI undergoing surgery under general anaesthesia in our hospital and compare it to that of obese patients.
- Trial name
- NCT03752593
- Testing
- ET Tube
- Where
- Bahrain
- Volunteers
- 200 people
- Sponsor
- King Hamad University Hospital, Bahrain
Pain, Postoperative Pain
A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries
Post-operative, throat pain, nausea and vomiting is a common occurrence in rhinology surgeries due to the use of throat packs during the procedure.
- Conditions
- Pain, Postoperative Pain, Bleeding, Nose Bleed
- Trial name
- NCT03678168
- Testing
- Throat Pack, Pharyngeal Tampons
- Where
- Bahrain
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- King Hamad University Hospital, Bahrain
Recurrent Implantation Failure
PRP in Recurrent Implantation Failure
The endometrial function and endometrial receptivity have been accepted to be major limiting factors in the establishment of pregnancy.
- Trial name
- NCT04085783
- Testing
- PRP
- Where
- Bahrain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dr. Kamal Rageh
Plantar Fasciitis
Comparing Steroid Injections and Platelet Rich Plasma Injections in the Treatment of Plantar Fasciitis
In cases of Plantar Fasciitis not responding to conservative management, minimally invasive techniques may be used. These include platelet rich plasma injections and corticosteroid injections.
- Trial name
- NCT01957631
- Testing
- Corticosteroid injection (Bupivacaine and Depo Medrol), Platelet rich plasma injection
- Where
- Bahrain
- Volunteers
- healthy volunteers welcome
- Sponsor
- King Hamad University Hospital, Bahrain
Sickle-Cell Disease
Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD
A Multi-Centre, Phase II, Randomized, Double-Blind, Placebo-Controlled Study to investigate Efficacy and Safety of Sevuparin Infusion for the Management of Acute Vaso-Occlusive Crisis (VOC) in Subjects with Sickle-Cell Disease…
- Trial name
- NCT02515838
- Testing
- Sevuparin
- Where
- 20 sites in Bahrain, Jamaica and 5 more
- Volunteers
- 147 people
- Sponsor
- Modus Therapeutics AB
Aortocoronary Bypass, Cardiac Surgery
Volatile Anesthetics to Reduce Mortality in Cardiac Surgery
There is initial evidence that the choice of anesthesia can influence survival in the specific setting of coronary artery bypass grafting surgery (CABG).
- Conditions
- Aortocoronary Bypass, Cardiac Surgery, Coronary Artery Bypass Grafting
- Trial name
- MYRIAD (NCT02105610)
- Testing
- desflurane, isoflurane, sevoflurane, total intravenous anesthetics
- Where
- 36 sites in Bahrain, Brazil and 11 more
- Volunteers
- 5,400 people
- Sponsor
- Università Vita-Salute San Raffaele
Preimplantation Diagnosis
Side of Embryo Biopsy Interfering Implantation Potential
Selection of side of embryo biopsy that will not interfering with implantation power of developed blastocyst embryo during biopsy procedure arranged for PGT.
- Trial name
- NCT02902614
- Testing
- Vegetal Pole blastomer embryo, Animal Pole blastomer embryo
- Where
- 2 sites in Bahrain, Egypt
- Volunteers
- 100 people
- Sponsor
- Ahmad Mustafa Mohamed Metwalley
Infertility
Novel Approach With Double Agent Artificial Oocyte Activation for Repeated Fertilization Failure Due to Combined Sperm and Oocyte Factor
Novel approach for Oocyte fertilization failure for difficult cases not respond to traditional methods of assisted reproduction as intracytoplasmic sperm injection.
- Trial name
- CISC (NCT02418416)
- Testing
- Oocyte double chemical activation
- Where
- 3 sites in Bahrain, Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital
Oocyte Fertilization
Artificial Oocyte Activation Comparing Tow Different Agents
Comparing the efficacy of tow factors for artificial Oocyte Activation for poor quality Oocytes and Teratozoospermia patients.
- Trial name
- NCT02424214
- Testing
- Artificial Oocyte activation, Ca Ionophore, Strontium Chloride
- Where
- 3 sites in Bahrain, Egypt
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital
Atrial Fibrillation
Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Latinamerica and EMEA Region
This international study is a prospective noninterventional observational cohort study of patients with non-valvular atrial fibrillation who are prescribed rivaroxaban under routine treatment conditions to prevent stroke or…
- Trial name
- XANTUS-EL (NCT01800006)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- 17 sites in Argentina, Azerbaijan and 15 more
- Volunteers
- 2,101 people
- Sponsor
- Bayer
Hepatitis B, Chronic
An Observational Cohort Study in Patients With Chronic Hepatitis B Receiving Pegasys
This observational, non-interventional cohort study will evaluate predictors of response in patients with chronic hepatitis B receiving standard of care Pegasys therapy. Efficacy and safety parameters will also be evaluated.
- Trial name
- NCT01011738
- Where
- 249 sites in Austria, Bahrain and 25 more
- Volunteers
- 1,842 people
- Sponsor
- Hoffmann-La Roche
Hepatitis C, Chronic
An Observational Study on The Prediction of Adverse Events in Patients With Chronic Hepatitis C Receiving a Long-Acting Interferon Plus Ribavirin (GUARD-C)
This observational study will assess factors leading to dose reductions/treatment discontinuations and the effect on sustained virological response in patients with chronic hepatitis C receiving a long-acting interferon (e.g.
- Trial name
- NCT01344889
- Where
- 260 sites in Albania, Algeria and 23 more
- Volunteers
- 4,459 people
- Sponsor
- Hoffmann-La Roche
Radiofrequency Ablation, Chronic Sacroiliac Joint Arthropathy
Radiofrequency in Sacroiliac Arthropathy;Bipolar RF 6 Points Versus Monopolar RF at 6 and 3 Points
Expecting using bipolar RF at six points, in spite of potentially consuming more intraoperative time, to be more effective and long lasting in the management of pain resultant from chronic sacroiliac joint arthropathy than the…
- Trial name
- RFSIBIMONO6 (NCT02382289)
- Testing
- radiofrequency ablation for sacroiliac joint arthropathy
- Where
- Bahrain
- Volunteers
- 60 people
- Sponsor
- King Hamad University Hospital, Bahrain
Non Small Cells Lung Cancer
Epidemiological Study to Describe Non Small Cell Lung Cancer Clinical Management Patterns in MENA. Lung-EPICLIN/ Gulf
The overall aim of the study is: To provide accurate and reliable information regarding NSCLC clinical management across MENA region in order to detect unmet medical needs of this disease in terms of: Patient and hospital…
- Trial name
- Lung-EPICLIN/G (NCT01562665)
- Where
- 3 sites in Bahrain, Qatar and 1 more
- Volunteers
- 25 people
- Sponsor
- AstraZeneca
Infertility
Management of Abnormally Fertilized Zygotes? InVitro Correction of 3PN
In this newly developed protocol, and idea, is to manage those abnormally developed zygotes from different ART procedures. The investigators developed the plan and requirements needed to select the target extra nucleus or…
- Trial name
- NCT02358759
- Testing
- Correction of abnormally fertilized oocytes
- Where
- 2 sites in Bahrain, Egypt
- Volunteers
- 22 people
- Sponsor
- Ahmad Mustafa Mohamed Metwalley
Relapsing Remitting Multiple Sclerosis (RRMS)
Observational Study to Analyse the Impact of Nurse Support and Disease Related Factors on Long- Term Adherence to Betaferon Treatment
The Study analyses the influence of selected factors on adherence to Betaferon treatment in patients with early multiple sclerosis (MS).
- Trial name
- BEACON (NCT00787657)
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 36 sites in Argentina, Bahrain and 34 more
- Volunteers
- 1,723 people
- Sponsor
- Bayer
Infertility
Evaluation Study Between Density Gradient and Swimming Down for Semen Processing
This study evaluates the quality of sperm produced after semen processing using Density Gradient (DG) and swimming down (SD).
- Trial name
- NCT02329704
- Testing
- Diff-Quik staining for morphology evaluation, Motility Evaluation for grade A and B, Concentration (mil/ml)
- Where
- 2 sites in Bahrain, Egypt
- Volunteers
- 100 people
- Sponsor
- Ahmad Mustafa Mohamed Metwalley
Infertility
Semen Processing for ICSI Using Swim-down and Density Gradient Methods
The investigators evaluate the feedback of using swim down semen processing method during preparation for ICSI and compare the results of pregnancy and embryos quality with the cases used density gradient method for their semen…
- Trial name
- NCT02328534
- Testing
- Blastocyst Formation Rate, Blastocyst Rate, Pregnancy Rate
- Where
- 2 sites in Bahrain, Egypt
- Volunteers
- 890 people
- Sponsor
- Ahmad Mustafa Mohamed Metwalley
Rheumatoid Arthritis
A Study of Tocilizumab as Monotherapy or in Combination With DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis
This open-label single-arm study will evaluate the safety, tolerability and efficacy of tocilizumab [RoActemra/Actemra] in patients with moderate to severe rheumatoid arthritis who experience an inadequate clinical response to a…
- Trial name
- NCT01089023
- Testing
- tocilizumab [RoActemra/Actemra]
- Where
- 9 sites in Bahrain, Iran and 3 more
- Volunteers
- 95 people
- Sponsor
- Hoffmann-La Roche