Clinical trials: in Burma
Malaria
Dynamics of Subclinical Malaria: Preliminary Study
This is a short longitudinal preliminary study that aims to describe the dynamics of low-density subclinical malaria to support the final study design of a subsequent matched cohort study.
- Trial name
- NCT03483571
- Where
- Burma
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Duke University
Stroke, Gait, Hemiplegic
Effect of Structured Progressive Task-Oriented Circuit Class Training With Motor Imagery on Gait in Stroke
The objectives of the study will be General Objective is to investigate the effect of TOCCT with MI on gait performance in patients with stroke. Speific Objevtives.
- Trial name
- NCT03436810
- Testing
- Motor imagery, Health education, Task-Oriented Circuit Class Training
- Where
- Burma
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Hepatitis C
Hepatitis C: Community Testing and Treatment (CT2 Study Myanmar)
Implementation-effectiveness hybrid trial assessing acceptability, feasibility and cost-effectiveness of community-based point-of-care testing and treatment for hepatitis C.
- Trial name
- CT2 (NCT03939013)
- Testing
- Xpert HCV VL
- Where
- 2 sites in Burma
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- Macfarlane Burnet Institute for Medical Research and Public Health Ltd
Gastric Cancer, Non-Atrophic Gastritis
Helicobacter Pylori Genome Project (HpGP)
Helicobacter pylori is a common bacterial infection. It can lead to severe stomach problems, including stomach cancer. Researchers want to look at samples of the bacteria. These H.
- Conditions
- Gastric Cancer, Non-Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT02788214
- Where
- 94 sites in United States, Algeria and 51 more
- Volunteers
- 1,000 people
- Sponsor
- National Cancer Institute (NCI)
Plasmodium Falciparum Malaria
Targeted Chemo-elimination (TCE) of Malaria
The overall aim of this study is two fold: 1. to pilot targeted chemo-elimination of plasmodium falciparum malaria in known areas of artemisinin resistance in South East Asia. 2.
- Trial name
- TME (NCT01872702)
- Testing
- malaria elimination using DP and low-dose primaquine
- Where
- 5 sites in Burma, Cambodia and 3 more
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Drug Resistant Malaria, Asymptomatic Infections
Drug Resistance Among Asymptomatic Infection
A cross-sectional study will be conducted in selected 2 sentinel sites for assessment of drug resistance falciparum and vivax among asymptomatic infection in migrant workers in Myanmar.
- Conditions
- Drug Resistant Malaria, Asymptomatic Infections, Migrant Workers
- Trial name
- NCT03648411
- Testing
- Drug resistance molecular markers
- Where
- Burma
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Department of Medical Research, Lower Myanmar
Osteoarthritis, Knee, Osteoarthritis
Low Intensity Pulsed Ultrasound Versus High Intensity Continuous Ultrasound Therapy in Knee Osteoarthritis
To compare the effects of low intensity pulsed ultrasound with high intensity continuous ultrasound in knee osteoarthritis
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Rheumatic Diseases, Musculoskeletal Diseases
- Trial name
- NCT04406337
- Testing
- Low intensity pulsed ultrasound, High intensity continuous ultrasound
- Where
- Burma
- Volunteers
- 86 people
- Sponsor
- Ministry of Health and Sports, Myanmar
The Prevalence of Scrub Typhus
Scrub Typhus RDT Study
Fever is one of most common presenting complaints in clinics in tropical countries. Rickettsial infections, enteric fever and leptospirosis are common and important causes of undifferentiated fever in Southeast Asia.
- Trial name
- NCT03269266
- Testing
- Scrub Typhus RDT Test
- Where
- 2 sites in Burma
- Volunteers
- 136 people
- Sponsor
- Myanmar Oxford Clinical Research Unit
Melioidosis Pneumonia
Causes of Pneumonia in Yangon
This study will evaluate a new point of care diagnostic test for the diagnosis of melioidosis pneumonia in patients attending outpatient clinics in Yangon, Myanmar
- Trial name
- NCT03578133
- Testing
- InBios® Active Melioidosis DetectTM-Lateral Flow Assay
- Where
- Burma
- Volunteers
- 300 people
- Sponsor
- Myanmar Oxford Clinical Research Unit
Rickettsiae Infections
Rickettsiae in Myanmar
Rickettsial infections have been found to be the second most common cause of non-malarial febrile illness in Southeast Asia, just after dengue, and are largely neglected treatable causes of morbidity and mortality.
- Trial name
- Rickettsiae (NCT03847870)
- Testing
- MORU in-house ELISA test followed by IFA if positive
- Where
- Burma
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Myanmar Oxford Clinical Research Unit
Helicobacter Pylori Infection
The Epidemiology and Optimal Treatment of Helicobacter Pylori in Myanmar
This study aims to: 1. Determine the prevalence of Helicobacter infection in Myanmar (this would be the largest ever series in the country) 2.
- Trial name
- NCT04132479
- Testing
- Clarithromycin 500mg, Amoxicillin 500mg, Tinidazole 500mg
- Where
- Burma
- Volunteers
- 313 people
- Sponsor
- Kirby Institute
Encephalitis
SouthEast Asia Encephalitis Project
Encephalitis, an acute inflammation of the central nervous system associated with neurologic dysfunction is of public health concern worldwide, because of its high mortality and neurological sequelae rates.
- Trial name
- SEAe (NCT04089436)
- Testing
- CSF sampling, Blood sampling, Nasopharyngeal and rectal sampling
- Where
- 7 sites in Burma, Cambodia and 2 more
- Volunteers
- 800 people
- Sponsor
- Institut Pasteur
Stroke
Sensorimotor Integration Exercises on Post-stroke Balance and Fall Efficacy
To study the effect of sensorimotor integration exercises on balance and fall efficacy in sub-acute stroke by performing 18 balance training exercises with three progressive steps.
- Trial name
- SMIE (NCT03584035)
- Testing
- sensory motor integration exercises, conventional physiotherapy
- Where
- 2 sites in Burma
- Volunteers
- 46 people
- Sponsor
- Mahidol University
Hepatitis C, Hepatitis B
Simplified Antiviral Treatment Strategy for Hepatitis C in Myanmar
The project will evaluate cost and treatment outcomes of a simplified hepatitis C virus (HCV) testing, treatment and care model integrated with HIV testing and treatment among key affected populations including people who inject…
- Conditions
- Hepatitis C, Hepatitis B, HIV Infections
- Trial name
- NCT03579576
- Testing
- sofosbuvir 400 mg/velpatasvir 100 mg (SOF/VEL) orally once daily for 12 weeks with or without weight-based ribavirin.
- Where
- 3 sites in Burma
- Volunteers
- 803 people
- Sponsor
- Right to Care
Plasmodium Falciparum Infection
Optimising Operational Use of Artemether-lumefantrine Comparing 3 Day Versus 5 Day
This is a randomised two arm study, comparing artemether-lumefantrine 3 days and 5 days treatment. Patients will be randomised in blocks of ten to one of the two treatment arms.
- Trial name
- AL3vs5 (NCT02020330)
- Testing
- Artemether-lumefantrine 3 days, Artemether-lumefantrine 5 days
- Where
- Burma
- Volunteers
- 150 people
- Sponsor
- University of Oxford
Child Mental Disorder, Behavior Problem
Effectiveness Study of a Treatment to Improve the Mental Health of Children and Adolescents
This randomized controlled trial evaluates the effectiveness of a psychotherapeutic intervention, the Common Elements Treatment Approach (CETA), to address the mental health needs of children and adolescents age 8-17 who have…
- Trial name
- NCT03075475
- Testing
- Common Elements Treatment Approach
- Where
- Burma
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Incomplete Abortion
Sublingual Misoprostol for the Treatment of Incomplete Abortion: Operations Research
This study will investigate the use of misoprostol for first-line treatment of incomplete abortion at tertiary hospitals in Myanmar.
- Trial name
- NCT02707653
- Testing
- Misoprostol
- Where
- 2 sites in Burma
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Malaria, Falciparum
A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC)
This study is an open-label randomised trial comparing standard ACT treatment with matching triple artemisinin-based combination therapies (TACTs), evaluating efficacy in safety and tolerability.
- Trial name
- TRACII (NCT02453308)
- Testing
- ACT, TACT
- Where
- 20 sites in Bangladesh, Burma and 6 more
- Volunteers
- 1,110 people
- Sponsor
- University of Oxford
Malaria Diagnosis, Malaria,Falciparum
Evaluation of the Performance of a hsRDT Versus cRDT in Reactive Case Detection of Malaria Infections
A systematic review assessing the role, appropriateness and benefits of the active case detection strategy, both proactive and reactive, in low malaria transmission settings.
- Trial name
- NCT03511443
- Testing
- hsRDT
- Where
- Burma
- Volunteers
- 1,980 people, healthy volunteers welcome
- Sponsor
- University Research Co, LLC
Hepatocellular Carcinoma
Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC)
The primary objective of this study is to assess the efficacy of SIRT as compared with Sorafenib in patients with locally advanced liver cancer in terms of overall survival (OS).
- Trial name
- SIRveNIB (NCT01135056)
- Testing
- SIR-Spheres, Sorafenib tosylate
- Where
- 29 sites in Brunei, Burma and 10 more
- Volunteers
- 360 people
- Sponsor
- Singapore General Hospital