Clinical trials: suspended, in Canada
Pregnant Women
Sleep Position Pattern Recording
The main goal of this study is to validate the accuracy of the body position detection by non-invasive wearable monitors (Skiin garments, Myant Medical Corp) during sleep in pregnant participants.
- Trial name
- NCT06286904
- Testing
- Skiin Garment system
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Myant Medical Corp.
Chronic Pain
DNIC Using Deep Learning and Artificial Intelligence
Chronic pain (CP) is disabling for people triggering important costs for society. A deficit of diffuse noxious inhibitory controls (DNIC) is one of the CP mechanisms.
- Trial name
- NCT04896827
- Testing
- Conditioned pain modulation test
- Where
- Canada
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
ME/CFS, Long COVID
Is Swimming a More Tolerable Form of Movement for Individuals With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome?
Individuals with ME/CFS experience profound exercise intolerance and post-exertional malaise. This remote (app-based) pilot study explores whether light, fully self-paced, swimming may be a tolerable form of movement for people…
- Conditions
- ME/CFS, Long COVID, Post- COVID-19 Syndrome, POTS - Postural Orthostatic Tachycardia Syndrome
- Trial name
- ME/CFS (NCT07454395)
- Testing
- Swimming, Cycling
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Major Depressive Disorder, Suicide
Identifying the Neural Basis of Capability for Suicide
Since capability for suicide involves overriding potential pain, and the opioid system plays a strong role in controlling pain perception, it follows that capability for suicide may be impacted by the opioid system.
- Conditions
- Major Depressive Disorder, Suicide, Suicidal Ideation, Psychiatric Illness
- Trial name
- NCT03327129
- Testing
- fMRI
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Bone Resorption, Bone Loss
Bone Response to Exercise and Energy Restriction in Young Adults
Cycling is commonly questioned whether it provides adequate mechanical strain on bone as many elite cyclists have been found to have a low bone mass.
- Trial name
- NCT04345250
- Testing
- Energy restriction
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Brock University
Type 1 Diabetes, Cardiovascular Risk Factor
Determinants of Cardiovascular Disease Risk Factors Among Youth With Type 1 Diabetes
Type 1 diabetes mellitus (T1D) is the most common form of diabetes among children and youth, and it is increasing around the world, particularly among children under 5 years.
- Trial name
- CARDEA (NCT04304729)
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Aphakia
Artisan Aphakia Lens for the Correction of Aphakia in Children
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
- Trial name
- NCT01547442
- Testing
- Artisan Aphakia Intraocular Lens
- Where
- 19 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ophtec USA
Aphakia
Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults
This study will determine the safety and effectiveness of the Artisan Aphakia Lens when used as a secondary implant to correct aphakia in adults.
- Trial name
- NCT01547429
- Testing
- Artisan Aphakia Intraocular Lens
- Where
- 18 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ophtec USA
Chronic Pain
Adverse Childhood Events Chronic Pain
There is data to suggest that early childhood physical, emotional and sexual trauma could contribute to the development of chronic pain later in life, but this has not been studied in the Canadian Forces.
- Trial name
- NCT05259878
- Testing
- Adverse Childhood Events
- Where
- 2 sites in Canada
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Canadian Forces Health Services Centre Ottawa
Sleep Apnea, Hypersomnia
Patient Outcomes in Unattended and In- Lab Polysomnography
This randomized controlled study will directly evaluate whether unattended polysomnography (level 2 sleep study) in individuals referred for sleep apnea or hypersomnia, including those with comorbidities of insomnia and…
- Trial name
- NCT05230394
- Testing
- Attended Polysomnography in the Lab, Unattended Polysomnography in the Home
- Where
- Canada
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Cerebra Medical
Anesthesia, Local, Needle Phobia
Needle-free Dental Anesthesia
Many patients experience pain and anxiety from traditional needle anesthesia and may avoid necessary dental treatments. The needle-free liquid jet injection(NFLJI) could solve these problems.
- Trial name
- NCT04493528
- Testing
- Meso-Jet, 2% lidocaine(xylocaine), Needle,2% lidocaine(xylocaine)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Glaucoma
Feasibility of Visual Field Testing With a Virtual Reality Headset
This study aim to determine the feasibility of using a virtual reality (VR) headset (HTC Vive) to test the visual field. The VR headset test will be compared to a conventional visual field test, using the Humphrey Field Analyzer.
- Trial name
- NCT03748654
- Testing
- Visual Field Testing
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brennan Eadie
Anesthesia
Magnesium for Shivering in Epidural Lidocaine Deliveries
Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing labor epidural anesthesia…
- Trial name
- Mag-SHIELD (NCT03439358)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Total Knee Arthroplasty
How Muscle and Tendon Properties Contribute to Functional Change Prior to and Following Knee Replacement
It is unknown how progressive physiological change in muscle and tendon contributes to loss of functional ability in patients undergoing total knee replacement between referral to surgery, and during post-surgery recovery.
- Trial name
- NCT04740073
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Impulsive Behavior
Transcranial Direct Current Stimulation for Impulsivity and Food-related Impulsivity in Obesity
In this study the investigators aim to assess whether transcranial direct current stimulation (tDCS; a safe non-invasive method for modulating the activity of specific brain regions) when applied over the orbitofrontal cortex…
- Trial name
- tDCS (NCT04218383)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Sarcopenia
Exercise and Branched Chain Amino Acids (BCAA)Requirements in Older Men
Likely, branched chain amino acid (BCAA) requirements are increased in older strength-trained (ST) individuals. If so, supplementation in this group will maximize muscle protein synthesis (MPS) and minimize loss of muscle with…
- Trial name
- NCT01931722
- Testing
- Branched chain amino acid, Strength training
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada