Clinical trials: in Colombia
Chronic Spontaneous Urticaria
Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab
The purpose of this extension study was to establish efficacy and safety of ligelizumab. This was assessed in adult and adolescent chronic spontaneous urticaria (CSU) patients who had completed a preceding ligelizumab study and…
- Trial name
- NCT04210843
- Testing
- Ligelizumab
- Where
- 273 sites in United States, Argentina and 43 more
- Volunteers
- 1,033 people
- Sponsor
- Novartis Pharmaceuticals
Hepatitis C Virus Infection
Screening for Hepatitis c in People Who Inject Drugs in Armenia-Colombia
Hepatitis C virus infection is a major cause of chronic hepatitis, cirrhosis, and liver cancer. The risk of developing cirrhosis for people with chronic infection with the virus ranges from 15% to 30% over 20 years.
- Trial name
- HCV-PIWD (NCT06463912)
- Testing
- Does not apply
- Where
- Colombia
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Asociación Colombiana de Hepatología
Ankylosing Spondylitis
Study to Demonstrate the Efficacy, Safety and Tolerability of an Intravenous Regimen of Secukinumab Compared to Placebo in Subjects With Active axSpA
The purpose of this global study was to demonstrate the efficacy, safety, and tolerability of an intravenous (i.v.) regimen of secukinumab compared to placebo in participants with active ankylosing spondylitis (AS) or…
- Trial name
- NCT04156620
- Testing
- Secukinumab
- Where
- 102 sites in United States, Belgium and 16 more
- Volunteers
- 527 people
- Sponsor
- Novartis Pharmaceuticals
Hemophilia A
ADVATE/ ADYNOVI Hemophilia A Outcome Database (AHEAD)
The purpose of the study is to document the natural history of hemophilia A disease and long-term outcomes in terms of effectiveness, safety and quality of life in participants receiving Antihemophilic Factor (Recombinant) …
- Trial name
- AHEAD (NCT02078427)
- Testing
- ADVATE, ADYNOVI
- Where
- 110 sites in Australia, Austria and 20 more
- Volunteers
- 951 people
- Sponsor
- Baxalta now part of Shire
Older People, Prehabilitation
Surgical Prehabilitation in Abdominal Surgery
Randomized clinical trial evaluating changes in functional capacity, postoperative complications and 30-day mortality in patients over 60 years of age undergoing major gastrointestinal surgery who participate in a multimodal…
- Conditions
- Older People, Prehabilitation, Surgical Procedure
- Trial name
- SPAS (NCT05057741)
- Testing
- Multimodal prehabilitation
- Where
- Colombia
- Volunteers
- 24 people
- Sponsor
- Universidad del Rosario
Hepatitis C Virus Infection
Adult Screening for Hepatitis c and Linkage to Treatment in Hospitals in Colombia
Introduction: Hepatitis C virus infection is a major cause of chronic hepatitis, cirrhosis, and liver cancer. The risk of developing cirrhosis for people with chronic infection with the virus ranges from 15% to 30% over a 20-year…
- Trial name
- HCVLINKAGE (NCT06155006)
- Testing
- rapid diagnostic test HCV Ab Plus Rapid test
- Where
- 2 sites in Colombia
- Volunteers
- 25,669 people, healthy volunteers welcome
- Sponsor
- Asociación Colombiana de Hepatología
Diabetes Mellitus, Type 1
Carbohydrate Count Aided by a Simulation in People With Type 1 Diabetes Mellitus. A Protocol for a Clinical Trial
Insulin remains the only approved treatment for type 1 diabetes mellitus patients and is used by many with type 2 diabetes. Carbohydrate counting is the most recommended way to prescribe prandial insulin dose because it is safe…
- Trial name
- NCT05181917
- Testing
- STUDIA app
- Where
- Colombia
- Volunteers
- 28 people
- Sponsor
- Hospital Pablo Tobón Uribe
Fractures or Dislocations
INternational ORthopaedic MUlticenter Study in Fracture Care (INORMUS)
Background: Worldwide, injuries from trauma represent a major public health problem. The World Health Organization (WHO) has deemed this problem as one of the most important global priorities, calling 2011-2020 the 'Decade of…
- Trial name
- INORMUS (NCT02150980)
- Where
- 69 sites in Argentina, Botswana and 24 more
- Volunteers
- 39,797 people
- Sponsor
- McMaster University
Mental Health Wellness 1
Emotional Intelligence Program for Adolescents With Antisocial Behavior (DYNAMIS)
This study assessed the effectiveness of an emotional intelligence program based on the Salovey and Mayer model among adolescents exhibiting antisocial behavior.
- Trial name
- DYNAMIS (NCT06124183)
- Testing
- The program comprises 12 sessions and additional activities to be carried out after each session, alongside counseling from the program's leading professionals
- Where
- Colombia
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Rheumatoid Arthritis
Long-term Follow-up Study of GLPG0634 in Active Rheumatoid Arthritis Participants
The primary objective of the study was to evaluate the long-term safety and tolerability of filgotinib (formerly GLPG0634) for the treatment of rheumatoid arthritis.
- Trial name
- DARWIN3 (NCT02065700)
- Testing
- Filgotinib
- Where
- 111 sites in United States, Argentina and 20 more
- Volunteers
- 739 people
- Sponsor
- Lakefront Biotherapeutics NV
Post-COVID-19 Syndrome, COVID-19
Evaluation of Treatment With Viusid in Post-COVID-19 Syndrome
Reports of long-lasting symptoms of COVID-19 are increasing, but little is known about the prevalence of risk factors or whether it is possible to predict a prolonged course at disease onset.
- Conditions
- Post-COVID-19 Syndrome, COVID-19, Dyspnea, Fatigue
- Trial name
- NCT06437210
- Testing
- Viusid Oral Solution
- Where
- Colombia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Catalysis SL
Familial Hypercholesterolemia
Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)
The main purpose of this study is to describe the safety and tolerability of 80 weeks of subcutaneous (SC) evolocumab when added to standard of care in children 10 to 17 years of age with familial hypercholesterolemia.
- Trial name
- HAUSER-OLE (NCT02624869)
- Testing
- Evolocumab
- Where
- 46 sites in United States, Australia and 21 more
- Volunteers
- 163 people
- Sponsor
- Amgen
Pain, Menstrual, Primary Dysmenorrhea
Music for Pain in Primary Dysmenorrhea
Primary dysmenorrhea is defined as lower abdominal pain that occurs during menses and is not secondary to any type of pelvic disease. It is considered the most common condition in reproductive age women.
- Trial name
- NCT03593850
- Testing
- Music group, Silence Group
- Where
- Colombia
- Volunteers
- 649 people, healthy volunteers welcome
- Sponsor
- Universidad del Rosario
Dyslipidemia
Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk
The primary objective was to evaluate the effect of treatment with evolocumab, compared with placebo, on the risk for cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary…
- Trial name
- FOURIER (NCT01764633)
- Testing
- Evolocumab
- Where
- 1,284 sites in United States, Argentina and 47 more
- Volunteers
- 27,564 people
- Sponsor
- Amgen
Paroxysmal Supraventricular Tachycardia
Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303
NODE-303 was a multi-center, open label study to evaluate the safety of etripamil NS in participants with Paroxysmal Supraventricular Tachycardia (PSVT).
- Trial name
- NCT04072835
- Testing
- Etripamil NS
- Where
- 124 sites in United States, Argentina and 3 more
- Volunteers
- 1,116 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Mesothelioma
Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patients
The purpose of this study is to test the effectiveness and tolerability of the combination of Nivolumab and Ipilimumab compared to Pemetrexed and Cisplatin or Carboplatin in patients with unresectable pleural mesothelioma.
- Trial name
- CheckMate743 (NCT02899299)
- Testing
- Nivolumab, Ipilimumab, Pemetrexed
- Where
- 109 sites in United States, Australia and 19 more
- Volunteers
- 605 people
- Sponsor
- Bristol-Myers Squibb
Arthritis, Rheumatoid
A 2-Year Phase 3 Study Of CP-690,550 In Patients With Active Rheumatoid Arthritis On Background Methotrexate
This study is designed to provide safety and efficacy data to support the development of CP-690,550 in patients with moderate to severe rheumatoid arthritis on background of methotrexate.
- Trial name
- NCT00847613
- Testing
- CP-690,550
- Where
- 115 sites in United States, Australia and 13 more
- Volunteers
- 800 people
- Sponsor
- Pfizer
Hypertensive Disorders of Pregnancy
Nursing Intervention for Knowledge and Self-care Behaviors in the Face of Hypertensive Disorders of Pregnancy
Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal and fetal morbidity and mortality worldwide. The lack of knowledge and self-care behaviors by the pregnant woman in the face of THE could be associated…
- Trial name
- EducaTHE (NCT05837962)
- Testing
- Nursing intervention to improve knowledge and self-care behaviors in the face of HDP
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Universidad de Antioquia
Congenital Heart Disease
Assessment of Patterns of Patient Reported Outcomes in Adults With Congenital Heart Disease - International Study II
This is an international, cross-sectional and descriptive study that aims to investigate differences in patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) and that aims to explore the…
- Trial name
- APPROACH-IS II (NCT04902768)
- Testing
- This is an observational study, there is no intervention
- Where
- 53 sites in United States, Argentina and 30 more
- Volunteers
- 8,415 people
- Sponsor
- KU Leuven
Dengue, Vector Borne Diseases
Sustainable Reduction of Dengue in Colombia: Vector Breeding Site Intervention With an Insecticidal Coating
Effective control of Aedes aegypti mosquitoes in breeding sites with high reproductive rates could have a major impact on reducing arbovirosis in endemic communities.
- Conditions
- Dengue, Vector Borne Diseases, Arbovirus Infections, Zika
- Trial name
- NCT06268691
- Testing
- Insecticide Coating INESFLY
- Where
- 2 sites in Colombia, Germany
- Volunteers
- 35,000 people, healthy volunteers welcome
- Sponsor
- Rocio Cardenas Sanchez