Clinical trials: open to volunteers, in Denmark
Tendinopathy
Tracking of Red Blood Cells Using Super Resolution Ultrasound in Persons With Healthy or Overuse Injured Tendons
The goal of this observational study is to test whether a new ultrasound method, called SUper Resolution ultrasound imaging of Erythrocytes (SURE), can image the small blood vessels found in tendons of persons with a tendon…
- Trial name
- SURE-TEND (NCT06142747)
- Testing
- Super-Resolution Ultrasound Imaging of Erythrocytes (SURE)
- Where
- Denmark
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Prostate Cancer Patients Undergoing External Radiation and Seed Implantation, High Risk Localised Prostate Carcinoma
Addition of Focal Boost to Primary Radiotherapy for Prostate Cancer in 12 or 20 Fractions
Every year, about 700 Danish men get radiotherapy for prostate cancer with a high-risk of later progression. The risk of relapse is about 40 % after 5 - 8 years, so we need better treatment for these patients in Denmark and…
- Conditions
- Prostate Cancer Patients Undergoing External Radiation and Seed Implantation, High Risk Localised Prostate Carcinoma, Locally Advanced Prostate Cancer, Unfavourable Intermediate Risk Prostate Cancer
- Trial name
- DAPROCA10 (NCT07343349)
- Testing
- Addition of focal boost and hypofractionation
- Where
- 3 sites in Denmark
- Volunteers
- 1,016 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lymphatic Disorders, Plastic Bronchitis
European Registry Study on Lymphatic Interventions
This European multicenter observational study aims to evaluate the real-world use, timing, and outcomes of lymphatic interventions in patients with congenital heart disease and/or primary lymphatic disorders.
- Conditions
- Lymphatic Disorders, Plastic Bronchitis, Protein Losing Enteropathy, Chylothorax
- Trial name
- EURO-LYMPH (NCT07131293)
- Testing
- Lymphatic intervention
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pulmonary Embolism
Reperfusion Treatment in Acute Pulmonary Embolism
International guidelines recommend immediate reperfusion with systemic thrombolysis (ST) as first-line treatment in high-risk pulmonary embolism (PE).
- Trial name
- PE-NORDIC (NCT07003646)
- Testing
- Catheter directed intervention, any device, Alteplase
- Where
- 13 sites in Denmark, Sweden
- Volunteers
- 220 people
- Sponsor
- Sahlgrenska University Hospital
Arthritis, Juvenile, Arthritis, Juvenile Idiopathic
Hypnotherapy for Needle-related Procedural Pain and Anxiety Management in a Pediatric Setting
The proposed study aims to evaluate the effectiveness of hypnotherapy as a non-pharmacological intervention for managing pain and anxiety during needle-related medical procedures in children aged 5 to 17 years.
- Conditions
- Arthritis, Juvenile, Arthritis, Juvenile Idiopathic, Lupus Erythematosus, Systemic, Dermatomyositis, Juvenile
- Trial name
- NCT07349667
- Testing
- Hypnotherapy
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aarhus University Hospital
Colonoscopy, Screening Colonscopy
What Influence Re-participation in the Danish Colorectal Screening Program.
This prospective observational study investigates how participants experience screening colonoscopy within the Danish colorectal cancer screening program and how these experiences relate to clinical findings, procedural factors…
- Conditions
- Colonoscopy, Screening Colonscopy, Pain
- Trial name
- NCT07353632
- Where
- 8 sites in Denmark
- Volunteers
- 8,000 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
The main aim of this study is to evaluate the pharmacokinetic (PK) comparability between TAK-881 and HYQVIA subcutaneous (SC) administration for maintenance therapy of CIDP.
- Trial name
- NCT06747351
- Testing
- TAK-881, HYQVIA, SC Investigational Needle Sets
- Where
- 52 sites in United States, Argentina and 9 more
- Volunteers
- 59 people
- Sponsor
- Takeda
Glucose Metabolism, Glucagon
Investigating the Acute Effects of Increasing Alanine Exposure in Healthy Participants
In this study the investigators will investigate the acute effects of increasing alanine exposure on metabolic parameters in healthy participants. Participants will participate in one study day.
- Trial name
- NCT07350512
- Testing
- alanine
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nicolai Jacob Wewer Albrechtsen
Treatment-refractory Schizophrenia, Treatment-resistant Schizophrenia
Cognitive Behavioral Therapy for Sleep and Circadian Disturbances (CBT-I) in Treatment-Resistant Schizophrenia
Using a randomized controlled design, the project aims to test if cognitive behavioral therapy interventions specifically targeting sleep disorders can significantly lessen the burden of the disrupted sleep in patients with…
- Trial name
- COSTS (NCT06749444)
- Testing
- CBT-I, CBT
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Jimmi Nielsen
Orthopedic Disorder
The Duration of Spinal Anaesthesia - a Prospective, Observational Cohort Study
Today, surgery in an ambulatory setting is preferred for many reasons. Total hip and knee arthroplasty (THA and TKA) are now procedures where patients can be sent home on the same day of the surgical procedure.
- Trial name
- Spinalrocks (NCT06459986)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Schizophrenia, Psychosis
Biomarkers in Clozapine-responding Schizophrenia
The outline of the current project is to establish a cohort of patients with treatment refractory schizophrenia eligible for clozapine, to identify clinical and biological characteristics of clozapine responding patients.
- Trial name
- BiCS (NCT05316883)
- Testing
- Clozapine
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Jimmi Nielsen
Heart Failure，Congestive, Atrial Fibrillation
The Cardio-share Telemedicine Cross-sector Collaboration Model for Managing Vulnerable Patients With Heart Failure
The goal of this observational study is to explore the potential of implementing a telemedicine-based cross-sector collaboration model to manage patients with frequent admissions with decompensated heart failure.
- Trial name
- ADHFQUAL-BFH (NCT06176131)
- Testing
- Telemedicine-based cross-sector collaboration for patient management
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Non-Melanoma Skin Cancer (NMSC), Basal Cell Carcinoma of Skin
The Role of Radiotherapy for the Management of Non-melanoma Skin Cancer in Denmark.
The goal of this observational study is to learn about the long-term effects of radiotherapy for people who were treated for non-melanoma skin cancer (NMSC) in the head and neck area.
- Conditions
- Non-Melanoma Skin Cancer (NMSC), Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma of the Skin
- Trial name
- DOSCA-2 (NCT07347392)
- Testing
- Follow-up visit at least two years after treatment
- Where
- Denmark
- Volunteers
- 2,900 people
- Sponsor
- University of Aarhus
Circadian Rhythms, Time Perception
The Effect of a Continuous 1-Hour Time Delay on Circadian Rhythms
The purpose of this study is to investigate whether the experience of a daily time delay can affect our internal circadian rhythm.
- Conditions
- Circadian Rhythms, Time Perception, Sleep
- Trial name
- NCT07317349
- Testing
- Fixed daily routine, Daily time delay
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Heart Failure, Heart Failure - NYHA II - IV
Remote Monitoring of Cardiac Mechanics in Heart Failure Patients
Heart failure is a severe heart disease, where the heart's ability to pump blood is unsatisfactory. The consequence is a high risk of hospitalization and death.
- Trial name
- SeismicHeart (NCT06885164)
- Testing
- Continuous monitroing
- Where
- 2 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University
Breastfeeding, Medication Safety
Medicines in Breast Milk and Estimated Infant Exposure
The MedMilk (Medication concentrations in human Milk) study investigates how selected medicines taken by breastfeeding women are transferred into human milk and whether this may affect the breastfed child.
- Conditions
- Breastfeeding, Medication Safety, Lactation, Drug Exposure Via Breast Milk
- Trial name
- MedMilk (NCT07346716)
- Testing
- Prescription Drugs
- Where
- 3 sites in Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Multiple Sclerosis, Chronic Pain
EXpain Trial - Exercise an a Non-pharmacological Pain-relieving Treatment in People With Multiple Sclerosis
The primary goal of this study is to test whether 12 weeks of progressive resistance exercise is an effective non-pharmacological treatment for reducing pain in people with multiple sclerosis and chronic pain.
- Conditions
- Multiple Sclerosis, Chronic Pain, Neuropathic Pain
- Trial name
- EXpain (NCT07342777)
- Testing
- Progressive resistance exercise, Usual Care followed by progressive resistance exercise
- Where
- Denmark
- Volunteers
- 116 people
- Sponsor
- University of Aarhus
Crohn's Disease of Terminal Ileum
Extended Mesenteric Resection in Ileocecal Crohn's Disease.
The EXCEED project aims to study the role of the mesentery in disease recurrence in Crohn's disease (CD), as evidence suggests that including the mesentery when doing ileocecal resections can significantly reduce recurrence…
- Trial name
- EXCEED (NCT06324838)
- Testing
- Standard laparoscopic ileocecal resection, Extended laparoscopic ileocecal resection
- Where
- Denmark
- Volunteers
- 204 people
- Sponsor
- Odense University Hospital
Atrial Fibrillation, Stroke
Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate
The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram.
- Trial name
- LAATAS (NCT06405750)
- Testing
- left atrial appendage closure
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Hemolysis
Feasibility Performance Study of ABL90 FLEX PLUS HEM
This feasibility performance study evaluates the ABL90 FLEX PLUS HEM device for its analytical performance in a clinical setting. The study aims to evaluate the performance of the hemolysis detection feature.
- Trial name
- ABL90FLEXHEM (NCT07345091)
- Testing
- The purpose of this study is to investigate the performance of the hemolysis detection function on the ABL90 FLEX PLUS HEM using arterial or venous whole blood
- Where
- Denmark
- Volunteers
- 95 people
- Sponsor
- Radiometer Medical ApS
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