Clinical trials: in Finland
Meningococcal Immunisation (Healthy Volunteers)
Study on a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Compared to Two Meningococcal Reference Vaccines in European Toddlers
Primary Objective: To demonstrate: the non-inferiority of the seroprotection rate (antibody titers greater than or equal to [>=] 1:8) to meningococcal serogroup C following the administration of MenACYW Conjugate or Nimenrix® as…
- Trial name
- NCT03890367
- Testing
- Meningococcal polysaccharide (serogroups A, C, Y, and W) tetanus toxoid Conjugate vaccine, Meningococcal polysaccharide group A, C, W-135 and Y Conjugate vaccine, Meningococcal group C polysaccharide Conjugate vaccine adsorbed
- Where
- 29 sites in Denmark, Finland and 1 more
- Volunteers
- 707 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Parkinson Disease, Idiopathic
Clinical Study of HER-096 in Healthy Volunteer Subjects and Patients With Parkinson's Disease
In this clinical study, the safety and tolerability of HER-096 and the way the body interacts with the drug (pharmacokinetics) will be investigated. The clinical study consists of two parts.
- Trial name
- NCT06659562
- Testing
- HER-096
- Where
- Finland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Herantis Pharma Plc.
Temporomandibular Disorders (TMD)
Digitally Trained Applied Relaxation for Treatment of Temporomandibular Pain
Temporomandibular disorders (TMD) are common musculoskeletal pain conditions related to masticatory muscles and temporomandibular joints.
- Trial name
- RCT (NCT07129096)
- Testing
- Applied Relaxation, Occlusal splint
- Where
- Finland
- Volunteers
- 124 people
- Sponsor
- University of Oulu
Breast Cancer
Amcenestrant (SAR439859) Plus Palbociclib as First Line Therapy for Patients With ER (+) HER2(-) Advanced Breast Cancer
Primary Objective: To determine whether Amcenestrant (SAR439859) in combination with palbociclib improves progression free survival (PFS) when compared with letrozole in combination with palbociclib in participants with estrogen…
- Trial name
- AMEERA-5 (NCT04478266)
- Testing
- SAR439859, Palbociclib, Letrozole
- Where
- 249 sites in United States, Argentina and 28 more
- Volunteers
- 1,068 people
- Sponsor
- Sanofi
Pediatric Pain
'My Life is Music' Group Therapy Model - a Feasibility Study for Adolescents With Persistent Pain
The aim of this multi-method feasibility study is to learn if a group therapy model using music can be applied in the treatment of adolescents with persistent pain.
- Trial name
- PedPainMusic (NCT06576219)
- Testing
- Group Music Therapy
- Where
- Finland
- Volunteers
- 24 people
- Sponsor
- Helsinki University Central Hospital
Pediatric Pain
Emotional Bodymaps in Pediatric Pain Patients and Their Parents.
The aims of this study are to find out how pain may alter the experience of emotions in the body in pediatric pain patients and how how their parent feel the emotions in their bodies.
- Trial name
- PedPainEmot (NCT05902234)
- Testing
- interdiciplinary treatment
- Where
- Finland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Carcinoma, Non Small Cell Lung
A Study of Aflibercept Versus Placebo in Patients With Second-Line Docetaxel for Locally Advanced or Metastatic Non-Small-Cell Lung Cancer
The primary objective of the study was to demonstrate overall survival improvement for aflibercept + docetaxel compared to docetaxel + placebo as second line treatment for participants with locally advanced or metastatic…
- Trial name
- VITAL (NCT00532155)
- Testing
- Aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®), Docetaxel (Taxotere®), Dexamethasone (pre- and post-medication for docetaxel)
- Where
- 32 sites in United States, Argentina and 30 more
- Volunteers
- 913 people
- Sponsor
- Sanofi
Lung Cancer, Surgery
The Cardiac Stress and Electrocardiographic Changes Caused by Lung Cancer Surgery
Lung cancer surgery causes significant changes in the small circulation as well as changes in the intrathoracic anatomy. The effects of lung cancer surgery on electrocardiography and the cardiac stress associated with the…
- Conditions
- Lung Cancer, Surgery, Arrhythmia, Myocardial Ischemia
- Trial name
- NCT05094843
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Tampere University Hospital
Histiocytosis
Histiocytosis in Injecting Drug Users
The goal of this observational study is to describe a new disease condition of histiocytosis related to injecting drug use, its preconditions, symptoms, signs, findings, and prognosis in a detailed and systematic patient series…
- Trial name
- NCT06573671
- Testing
- Chitotriosidase, Mass spectrometry, scanning electron microscope with energy-dispersive X-ray spectroscopy
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Tampere University Hospital
Tonsil Disease, Tonsillitis
Intracapsular Tonsillectomy in Adults
Comparing the classical extracapsular tonsillectomy (TE) performed with electrosurgery to intracapsular approaches (SIPT) by coblation or microdebrider. The patient group is adults with recurrent or chronic tonsillitis
- Conditions
- Tonsil Disease, Tonsillitis, Tonsillitis Acute, Tonsillitis Chronic
- Trial name
- NCT03654742
- Testing
- tonsillectomy
- Where
- Finland
- Volunteers
- 167 people
- Sponsor
- Turku University Hospital
Melanoma
A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma
The purpose of this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab monotherapy in treating unresectable melanoma or melanoma that has spread.
- Trial name
- RELATIVITY-047 (NCT03470922)
- Testing
- Relatlimab, Nivolumab
- Where
- 127 sites in United States, Argentina and 23 more
- Volunteers
- 714 people
- Sponsor
- Bristol-Myers Squibb
Aortic Valve Stenosis
FORWARD PRO Study Interventional Post-market Study With the Evolut™ PRO System
Prospective, single-arm, multi-center, interventional post-market study. After signing informed consent, eligible subjects will be implanted with the CE marked Evolut™ PRO system.
- Trial name
- NCT03417011
- Testing
- Medtronic CoreValve™ Evolut™ PRO System (Evolut™ PRO System)
- Where
- 39 sites in Austria, Belgium and 12 more
- Volunteers
- 638 people
- Sponsor
- Medtronic Cardiovascular
Overweight, Nutrition Disorder, Child
Fit Child - Clinical Study on Weight Control
Children with abnormal weight development of BMI will be given either placebo or a probiotic protein formula and measures of weigh gain during a 3-mont treatment will be conducted
- Conditions
- Overweight, Nutrition Disorder, Child, Weight Change, Body
- Trial name
- FITCHI (NCT03196453)
- Testing
- Probiotic
- Where
- Finland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Turku University Hospital
Attention Deficit Hyperactivity Disorder
Virtual Reality in Rehabilitation of Executive Functions in Children With Attention Deficit Hyperactivity Disorder.
Attention deficit hyperactivity disorder (ADHD) is caused by an abnormality in the development of the central nervous system. Children with attention and executive function difficulties often need long-lasting rehabilitation and…
- Trial name
- VREALFUN-ADHD (NCT06123741)
- Testing
- Parental Guidance, Virtual Reality Game
- Where
- Finland
- Volunteers
- 88 people
- Sponsor
- Merja Nikula
Pancreatic Cancer Resectable
Neoadjuvant Treatment vs Upfront Surgery for Left-Sided Pancreatic Cancer
Pancreatic cancer is one of the most treatment resistant malignancies, often diagnosed at a late stage and associated with poor survival. The 5-year overall survival rate remains around 10%.
- Trial name
- LEFT-PANC (NCT07155629)
- Testing
- mFOLFIRINOX neoadjuvant chemotherapy / Nab-paclitaxel and gemcitabine
- Where
- 2 sites in Finland
- Volunteers
- 381 people
- Sponsor
- Helsinki University Central Hospital
Mild to Moderate Alzheimer's Disease
GV1001 Subcutaneous(SC) for the Treatment of Mild to Moderate Alzheimer's Disease (AD)
The current study is being conducted by the Sponsor to evaluate the efficacy and safety of GV1001 (0.56 mg and 1.12 mg) administered subcutaneously as a treatment for mild to moderate Alzheimer's disease (AD).
- Trial name
- NCT05189210
- Testing
- GV1001 0.56mg, GV1001 1.12mg
- Where
- 35 sites in United States, Finland and 6 more
- Volunteers
- 199 people
- Sponsor
- GemVax & Kael
Low Back Pain, Low Back Pain, Recurrent
Movement Control Exercises and Fascial Manipulation in Chronic Low Back Pain
Subjects are recruited from the attendees of the multidisciplinary low back pain rehabilitation group before it takes place in University Hospital of Oulu at Physical and Rehabilitation Medicine (PRM) unit.
- Trial name
- NCT03270631
- Testing
- FM and MCE
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- Oulu University Hospital
Acute Bronchiolitis
High Flow Nasal Cannula Weaning in Acute Bronchiolitis
The goal of this clinical study is to compared two different strategies to end high flow nasal cannula treatment in acute bronchiolitis.
- Trial name
- NCT06321133
- Testing
- High flow nasal cannula immediate ending, High flow nasal cannula weaning
- Where
- 4 sites in Finland
- Volunteers
- 50 people
- Sponsor
- Kuopio University Hospital
Neoplasms
A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer
This is a 2 part study. Part 1 is to evaluate the efficacy and safety of dostarlimab plus carboplatin-paclitaxel followed by dostarlimab versus placebo plus carboplatin-paclitaxel followed by placebo; and Part 2 is to evaluate…
- Trial name
- RUBY (NCT03981796)
- Testing
- Dostarlimab, Carboplatin, Paclitaxel
- Where
- 169 sites in United States, Belarus and 18 more
- Volunteers
- 785 people
- Sponsor
- Tesaro, Inc.
Acute Coronary Syndrome
Ticagrelor and ASA vs. ASA Only After Isolated Coronary Artery Bypass Grafting in Patients With Acute Coronary Syndrome
The study is a Randomised Registry-based Clinical Trial (RRCT) to assess whether dual antiplatelet therapy with ticagrelor and ASA compared to ASA alone improves outcome after isolated CABG in patients with acute coronary…
- Trial name
- TACSI (NCT03560310)
- Testing
- Ticagrelor 90mg twice daily and ASA 75-100 mg daily, ASA 75-160 mg daily
- Where
- 22 sites in Denmark, Finland and 3 more
- Volunteers
- 2,201 people
- Sponsor
- Vastra Gotaland Region
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