Clinical trials: in Finland
Fetal Heart Rate Tracing
Ability of the Polar Wearables to Detect Fetal Heart Rate - Pilot Clinical Study
The aim of this clinical pilot study is 1. to evaluate the ability of the wearables to detect fetal heart rate 2. to evaluate the ability to distinguish the fetal ECG from the ECG of the mother The participating pregnant women…
- Trial name
- NCT06683183
- Where
- Finland
- Volunteers
- 11 people
- Sponsor
- Anna Axelin
Occupational Diseases, Overweight and Obesity
Nutrition Apps in Occupational Healthcare (Pilot Study of the FOODNUTRI Project)
The aim of this study is to investigate (1) the user experiences and usability of the nutrition apps (the Finnish Nutrition Navigator and the Finnish Nutrition Path) in occupational health care from the perspective of both…
- Conditions
- Occupational Diseases, Overweight and Obesity, Dyslipidemias, Hypertension
- Trial name
- NCT06923735
- Testing
- Utilization of the Finnish Nutrition Navigator and the Finnish Nutrition Path
- Where
- Finland
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Prostate Cancer
A Randomized Trial of Early Detection of Clinically Significant Prostate Cancer (ProScreen)
A population-based randomised trial of prostate cancer screening will be carried out. A total of approximately 117,200 men aged 50-63 in Helsinki and Tampere are randomised to intervention (screening) or control arm.
- Trial name
- ProScreen (NCT03423303)
- Testing
- Prostate cancer screening
- Where
- 2 sites in Finland
- Volunteers
- 17,400 people, healthy volunteers welcome
- Sponsor
- Tampere University
Cervical Cancer Screening
Self- Sampling in Cervical Cancer Routine Screening
SELF-SAMPLING IN CERVICAL CANCER ROUTINE SCREENING (FALCON) -Study implements a self-sampling option for the non-attendees of the national cervical cancer screening program in the Wellbeing Services County of Pirkanmaa.
- Trial name
- FALCON (NCT06931184)
- Testing
- self-sampling
- Where
- Finland
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Exercise Training, Healthy
Why do People Respond Differently to Resistance Training?
It is well known that regular resistance training (RT) can have health benefits. However, considerable heterogeneity in RT responses has been observed.
- Conditions
- Exercise Training, Healthy, Skeletal Muscle Hypertrophy
- Trial name
- PreEx (NCT05874986)
- Testing
- Resistance training
- Where
- Finland
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
NAFLD, NASH
LITMUS Imaging Study
The LITMUS Imaging Study is a prospectively recruited, observational study of patients with histologically characterised non-alcoholic fatty liver disease (NAFLD).
- Conditions
- NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Liver
- Trial name
- NCT05479721
- Where
- 18 sites in United States, Finland and 8 more
- Volunteers
- 450 people
- Sponsor
- University of Oxford
Multiple Sclerosis
Exploring Pathology Related to Slowly Expanding Lesions Using Advanced Imaging
This is an open, follow-up study to compare the performance of three critical imaging methods to detect chronic active lesions in Multiple Sclerosis (MS) in vivo.
- Trial name
- SELPET (NCT06460077)
- Where
- Finland
- Volunteers
- 15 people
- Sponsor
- Turku University Hospital
Oral Immunotherapy for Food Allergy, Tree Nut Allergy
The NACHO Trial (Nut Allergy Children OIT)
Most food allergies that begin in early childhood are mild and resolve by school age, but nut allergies persist in about 80-90% of individuals into adulthood.
- Conditions
- Oral Immunotherapy for Food Allergy, Tree Nut Allergy, Cashew Nut Allergy
- Trial name
- NCT06930950
- Testing
- Cashew nut oral immunotherapy
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- HUS Skin and Allergy Hospital
Cancer, Hearing Loss Ototoxic
The Effect of Cancer Treatments on Speech Perception in Noise, Cognition, and Hearing-Related Quality of Life
The study will assess the effect of cancer treatments on speech perception in noise, cognition, and hearing-related quality of life by monitoring 200 cancer patients receiving standard care for their underlying malignancy.
- Conditions
- Cancer, Hearing Loss Ototoxic, Cognitive Decline, Quality of Life
- Trial name
- CaSPiN (NCT06551857)
- Testing
- Chemotherapy, chemoradiation, radiation therapy
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Chronic Pancreatitis
The Effect of Vitamin D Substitution on the Development of Chronic Pancreatitis
Acute pancreatitis (AP) may develop to chronic pancreatitis (CP). In Finland, the ethiology is alcohol in about 80% of the cases.
- Trial name
- NCT02965898
- Testing
- Vitamin D 100ug, Vitamin D 10ug
- Where
- Finland
- Volunteers
- 260 people
- Sponsor
- Tampere University Hospital
Multiple Sclerosis
Effect of Teriflunomide Treatment on Microglial Activation in an MS Patient Cohort at Risk of Progression
To evaluate the effect of teriflunomide treatment on microglial activation in late stage multiple sclerosis.
- Trial name
- TERIPET (NCT03368677)
- Where
- Finland
- Volunteers
- 26 people
- Sponsor
- Turku University Hospital
Pain, Postoperative, Anesthesia, Local
Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery
This study aims to investigate the effect of transversus thoracis muscle plane block (TTP), using repeated boluses of ropivacaine via catheter, on postoperative pain and oxycodone consumption after elective cardiac surgery with…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Coronary Artery Disease, Heart Valve Diseases
- Trial name
- TTPcat (NCT04916418)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Preventive Medicine
Preventing Chronicity of Sub-acute Low Back Pain by Altering the Neural Emotional Response to Pain
Aim of the study It could be stated that chronification of low back pain in some respects depends on the emotional reactions to the acute pain state.
- Trial name
- NCT05450263
- Testing
- Interoceptive exposure
- Where
- Finland
- Sponsor
- Orton Orthopaedic Hospital
Clostridioides Difficile Infection
FMT in Initial CDI
The study explores fecal microbiota transfer via retention enema after the first clostridioides difficile episode.
- Trial name
- FinCDI (NCT05257538)
- Testing
- FMT
- Where
- Finland
- Volunteers
- 140 people
- Sponsor
- Turku University Hospital
Degenerative Joint Disease
EU Safety and Efficacy Study Regarding the R3 Acetabular Hip System
The objective of this study is to determine the long-term safety and effectiveness from the R3 Acetabular Hip System. The study hypothesis is that implant survivorship of the R3 cup is at least 97% at 3 years, 95% at 5 years, 93%…
- Trial name
- NCT04399928
- Testing
- Total Hip Arthroplasty
- Where
- 8 sites in Belgium, Denmark and 5 more
- Volunteers
- 479 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Mild Alzheimer's Disease
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS-MAPTRx in Patients With Mild Alzheimer's Disease
The purpose of this study was to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of IONIS-MAPTRx in patients with Mild Alzheimer's Disease.
- Trial name
- NCT03186989
- Testing
- IONIS MAPTRx
- Where
- 13 sites in Canada, Finland and 4 more
- Volunteers
- 46 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
COPD (Chronic Obstructive Pulmonary Disease)
Virtual Pulmonary Rehabilitation Program for COPD Patients; a Pilot Study
The goal of this pilot study is to investigate the feasibility of a virtual rehabilitation program in COPD patients. The main questions it aims to answer are: 1.
- Trial name
- e-PURE (NCT06915740)
- Testing
- Exercise
- Where
- 2 sites in Finland
- Volunteers
- 50 people
- Sponsor
- Turku University Hospital
Recurrent Ovarian Carcinoma
Atezolizumab With Bevacizumab and Chemotherapy vs Bevacizumab and Chemotherapy in Early Relapse Ovarian Cancer
This is a phase III, randomized, partially blinded, multicenter trial to evaluate the efficacy and safety of atezolizumab plus bevacizumab and chemotherapy compared to placebo plus bevacizumab and chemotherapy in patients with…
- Trial name
- NCT03353831
- Testing
- Bevacizumab, Atezolizumab, Chemotherapy
- Where
- 111 sites in Austria, Belgium and 10 more
- Volunteers
- 574 people
- Sponsor
- AGO Research GmbH
Hypertrophy, Exercise Training
Resistance Training, Detraining, and Retraining Study 2024 (TraDeRe2024)
The goals of our research project are to identify factors explaining inter-individual variation in responses to resistance training (RT) and the baseline determinants underlying an individual's sensitivity to respond to RT.
- Conditions
- Hypertrophy, Exercise Training, Skeletal Muscle Atrophy, Healthy
- Trial name
- TraDeRe (NCT06573086)
- Testing
- Resistance Training
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Violence
More Effective Violence Risk Management - eDASA+APP FI
The main goal of this study is to evaluate if the Finnish version of eDASA+APP (electronic Dynamic Appraisal of Situational Aggression + Aggression Prevention Protocol), a clinical decision support system (CDSS), has an impact on…
- Trial name
- eDASA+APP FI (NCT06342531)
- Testing
- eDASA+APP FI
- Where
- Finland
- Volunteers
- 26 people
- Sponsor
- University of Turku
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