Clinical trials: in Guadeloupe
Metabolic Diseases, Diabetes Mellitus (Type 2)
Specificities of Atypical Non AutoImmune Diabetes (ANAID) in the French West Indies
Genetics variants could be involved in atypical non-autoimmune diabetes revealed by ketoacidosis. The objective of this research will be to determine the relationships between the genetic variants already described in known…
- Conditions
- Metabolic Diseases, Diabetes Mellitus (Type 2), Genetic Variation, Genetic Profile
- Trial name
- DiAGeNA (NCT07576374)
- Where
- Guadeloupe
- Volunteers
- 118 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Esophageal Atresia
National Register of Oesophageal Atresia
The esophageal atresia is a group of birth defects including a break in continuity of the esophagus with or without persistent communication with the trachea (tracheoesophageal fistula), sometimes associated (from 50%) of other…
- Trial name
- REGATE (NCT02883725)
- Testing
- data collection
- Where
- 37 sites in France, Guadeloupe and 1 more
- Volunteers
- 1,460 people
- Sponsor
- University Hospital, Lille
Very Preterm Birth
EPIPAGE2 Cohort Study Follow up at Five and a Half Years
Epipage 2 (epidemiologic study on small-for-gestational-age children) is a nationwide study implemented to improve our knowledge of the outcome of preterm children in France.
- Trial name
- EPIPAGE2 (NCT03078439)
- Testing
- Medical and neuropsychological assessments
- Where
- 98 sites in France, French Guiana and 2 more
- Volunteers
- 3,404 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Prostate Cancer
Cost-utility of Focal HIFU vs Prostatectomy
Medico-Economic Randomized Trial comparing Focal HIFU Treatment to Radical Prostatectomy in Patients with Favorable Intermediate Risk Prostate Cancer
- Trial name
- EMERHIT (NCT05710861)
- Testing
- F-HIFU, Radical Prostatectomy
- Where
- 20 sites in France, Guadeloupe
- Volunteers
- 346 people
- Sponsor
- University Hospital, Bordeaux
Diabetes
Interventional Clinical Trial Evaluating COVER PATCH CAPTEUR PROTECT Support Solutions for Continuous Glucose Monitoring Sensors in Patients With Diabetes
The aim of this clinical trial is to evaluate whether the COVER PATCH adhesive patch can improve the adhesion of continuous glucose monitors (CGMs).
- Trial name
- ICP-COVERPATCH (NCT07018180)
- Testing
- Use of COVER patchs for continuous glucose monitoring sensor
- Where
- 7 sites in France, Guadeloupe
- Volunteers
- 194 people
- Sponsor
- CAPTEUR PROTECT
Thyroid Cancer
ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify Outcomes in Low-risk Differentiated Thyroid Cancer
Prospective randomized open phase III non-inferiority trial in cT1bT2N0 papillary thyroid carcinoma comparing: total thyroidectomy alone (experimental group) versus total thyroidectomy + Prophylactic Neck Dissection PND…
- Trial name
- ESTIMABL3 (NCT03570021)
- Testing
- total thyroidectomy with bilateral prophylactic central compartment (level VI) neck dissection, total thyroidectomy alone without neck dissection
- Where
- 21 sites in France, Guadeloupe and 1 more
- Volunteers
- 352 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Obesity
Endoscopic Sleeve Gastroplasty (ESG) Prospective Trial for Obesity (EGO-Trial)
EGO-Trial is the first multicenter study in France which aims to evaluate the efficacy of Endoscopic Sleeve Gastroplasty (ESG) in patients with obesity.
- Trial name
- NCT07449520
- Testing
- Endoscopic sleeve gastroplasty
- Where
- 10 sites in France, Guadeloupe
- Volunteers
- 300 people
- Sponsor
- IHU Strasbourg
HIV
Quality of Care in French HIV Infected Patients
The objective of the Dataids cohort is to continue a long-term, prospective collection of clinical, laboratory and therapeutic data on a large cohort of HIV infected patients seeking care in 15 HIV centers in France in order : 1.
- Trial name
- Dataids_PEC (NCT02898987)
- Where
- 39 sites in France, Guadeloupe and 1 more
- Volunteers
- 30,000 people
- Sponsor
- DatAids
Pemphigus, Dermatologic Disease
Comparison of a Personalized Maintenance Therapy With the Standard Treatment in Pemphigus
Pemphigus diseases are life-threatening chronic autoimmune blistering diseases characterized by split formation within the epidermis and surface-close epithelia accompanied by acantholysis.
- Trial name
- RITUX4 (NCT05898308)
- Testing
- RiTUXimab Injection
- Where
- 34 sites in France, Guadeloupe
- Volunteers
- 133 people
- Sponsor
- University Hospital, Rouen
HIV Prevention
Dat'Aids Prevention
DatAIDS prevention is a cohort study of HIV prevention in over 23 HIV sites in France including overseas, aiming to describe HIV prevention in every aspect including HIV screening, STI and hepatitis screening, post-exposure…
- Trial name
- NCT03795376
- Where
- 31 sites in France, Guadeloupe and 1 more
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- DatAids
High Blood Pressure
STUDY OF THE DOUBLE POLYMORPHISM (THR 555ILE) AND (GLU568PRO) OF THE CORIN GENE AS A RISK FACTOR FOR ARTERIAL HYPERTENSION IN A POPULATION OF AFRICAN DESCENT IN GUADELOUPE
Cardiovascular disease (CVD) mortality is the leading cause of death in high-income countries (particularly the United States), accounting for 23.1% of all deaths It has been established over several decades that hypertension…
- Trial name
- HTAG-CORIN (NCT07330804)
- Testing
- double polymorphism
- Where
- 2 sites in Guadeloupe
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)
Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population (AdipoDROMExpo)
Metabolic Dysfunction Associated Liver Disease (MASLD) is associated with metabolic syndrome, and PNPLA3 variants are known to be implicated in intrahepatic lipid accumulation and linked to lipotoxicity.
- Trial name
- AdipoDROMExpo (NCT07330830)
- Where
- 3 sites in French Guiana, Guadeloupe and 1 more
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
HELICOBACTER PYLORI INFECTIONS, Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis)
Prevalence of Helicobacter Pylori on Patients With Chronic Inflammatory Bowel Disease (IBD) at the CHU of Guadeloupe
Clinical and experimental data suggest that dysbiosis may play a pivotal role in the pathogenesis of intestinal bowel disease (IBD).
- Trial name
- HP-MICI (NCT07292454)
- Testing
- Biopsies
- Where
- Guadeloupe
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Chronic Kidney Diseases
Chronic Kidney Disease : Role of Biological Factors and Apolipoprotein L1 Encoding Gene (APOL1)
Chronic kidney disease (CKD) is a major global public health issue. The present project focuses on the role of apolipoprotein L1 (APOL1) in patients with stage 4 CKD (glomerular filtration rate between 15 and 29 mL/min/1.73 m²).
- Trial name
- APOL1 (NCT07288723)
- Where
- Guadeloupe
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Sickle Cell Anemia
The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell Hemoglobin C Disease (SC)
The primary aim of this study is to determine the implication of micro and macro vascular function on the clinical severity of SCD (SS, SC, Sß°) adults.
- Trial name
- VASCUDREPA (NCT07277023)
- Testing
- The influence of micro-and macro vascular dysfunction on clinical severity in adults with sickle cell anemia (SS) and sickle cell hemoglobin C disease (SC)
- Where
- Guadeloupe
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Sickle Cell Disease, Dyslipidemia
Lipid Balance in Adult Sickle Cell Patients
This study aims to describe and/or searches for, in cohorts of adult sickle cell anemia (SCA) and SC sickle cell patients living in the French West Indies and followed by SCD Reference and Competence Centers: 1-lipids profiles…
- Conditions
- Sickle Cell Disease, Dyslipidemia, Complication
- Trial name
- HDL2 (NCT05780775)
- Testing
- HDL2
- Where
- Guadeloupe
- Volunteers
- 116 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Heart Failure, Remote Consultation, Teleconsultation
Comparison Between a Robotic Tele-echo-cardiography Technique and a Standard Echocardiography in the Management of Heart Failure in the Guadeloupe Archipelago Between the University Hospital of Guadeloupe and the Marie-Galante Hospital
The TERdeblue-S study is a feasibility study of robotic remote echocardiography, not only in terms of technology but also in terms of its integration into a telemedicine system to improve access to the heart failure management…
- Conditions
- Heart Failure, Remote Consultation, Teleconsultation, Echocardiography, Doppler
- Trial name
- TER de blueS (NCT07265986)
- Testing
- in situ echocardiography (EIS), two-dimensional remote echocardiography (TER)
- Where
- 3 sites in Guadeloupe
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Dermatomyositis
Severity Factors of Dermatomyositis in the Caribbean Population - DM-ANTILLES
Dermatomyositis is a rare chronic autoimmune and inflammatory disease that affects the skin and striated muscles. Its prognosis is linked to visceral involvement (lungs, heart, and oropharyngeal region) and to the possible…
- Trial name
- DM-ANTILLES (NCT07265999)
- Where
- Guadeloupe
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Mental Disorder, Schizophrenia Diagnosis
Validation of a VOICE MAnagement Program in Schizophrenia VVoice MAPS
Approximately 25-50% of patients with schizophrenia experience treatment-resistant Auditory Verbal Hallucinations (AVHs), which contribute to the development of associated psychopathological disorders (e.g., anxiety, depression…
- Trial name
- PROGEVs (NCT07266376)
- Testing
- Integrative group therapy
- Where
- Guadeloupe
- Volunteers
- 116 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Incidence of ZIKV Infection on Fetus During the Pregnancy
Zika Virus Infection's Pregnancy Consequences in French Department of America
The Zika (ZIKV) epidemic has spread into the three French Overseas Departments in the Caribbean (DFAs). It is therefore urgent to set up tools to collect clinical and paraclinical data for the evaluation of potential…
- Trial name
- ZIKA-DFA-FE (NCT02916732)
- Where
- 4 sites in French Guiana, Guadeloupe and 1 more
- Volunteers
- 26,980 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France