Clinical trials: in Haiti
HIV-1 Infection
HPV Test-and-Treat-Strategy Versus Cytology-based Strategy for Prevention of CIN2+ in HIV-Infected Women
Women sometimes develop cancer in an area called the cervix, which is the opening to the uterus, or womb. Women who have HIV are more likely to get this kind of cancer than women who do not have HIV.
- Trial name
- NCT01315353
- Testing
- Cervical Cryotherapy, Loop Electrosurgical Excision Procedure (LEEP)
- Where
- 13 sites in Botswana, Haiti and 5 more
- Volunteers
- 467 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV Infection, Tuberculosis
Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV
There is a rapidly-growing need to identify evidence-based, safe, and effective co-treatment regimens for HIV-related tuberculosis (TB) among patients who require protease inhibitor (PI)-based antiretroviral therapy (ART).
- Trial name
- NCT01601626
- Testing
- Standard-dose Lopinavir/Ritonavir, Double-dose Lopinavir/Ritonavir, Raltegravir
- Where
- 9 sites in Brazil, Haiti and 3 more
- Volunteers
- 71 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Cervical Cancer, Human Papillomavirus
Accuracy of Portable Colposcopy and HPV Genotypes Among HIV+ Women
This study will evaluate the effectiveness of portable colposcopy when compared to conventional colposcopy (25x magnification of the cervix, the gold standard) and Visualization Inspection with Acetic acid (VIA, with 1x…
- Conditions
- Cervical Cancer, Human Papillomavirus, Human Immunodeficiency Virus
- Trial name
- NCT02338141
- Testing
- Portable colposcopy (Cerviscope), Conventional colposcopy (Wallach Zoomscope)
- Where
- Haiti
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Duke University
Amblyopia, Myopia
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
Screening of haitian children between the ages of 3 and 6 years old for amblyogenic risk factors with the use of the Spot photoscreener. The photoscreener results will be compared to the complete ophthalmologic evaluation.
- Conditions
- Amblyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- POPH (NCT02655432)
- Testing
- Spot photoscreener, Ophthalmologic evaluation, Cyclopleged refraction
- Where
- 3 sites in Haiti
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université de Montréal
Major Depression
Measurement-based Care for Depression in Resource-Poor Settings
Depression is often the most prevalent mental health problem among people living with HIV (PLWH) worldwide, and if not adequately treated, it may impair response to antiretroviral treatment (ART) and the ability of individuals to…
- Trial name
- MBC (NCT02916238)
- Testing
- Fluoxetine, Enhanced Usual Care
- Where
- Haiti
- Volunteers
- 140 people
- Sponsor
- Florida International University
HIV
Same-Day HIV Testing and Treatment Initiation to Improve Retention in Care
The purpose of this study is to determine if same-day HIV testing and antiretroviral therapy (ART) initiation improves retention in care (as measured by the proportion of participants who are alive and in-care with an…
- Trial name
- NCT01900080
- Testing
- Same-Day HIV testing and ART initiation, Standard ART Initiation, Sub-Study: Same-Day ART, CD4 Count >500
- Where
- Haiti
- Volunteers
- 814 people
- Sponsor
- Brigham and Women's Hospital
HIV, Food Insecurity
Tailored Nutrition and Food Security Interventions in Comprehensive HIV Care
The study hypothesizes that one form of food supplement to HIV-infected individuals in Haiti (ready-to-use-supplementary food) will result in improved HIV, nutrition and quality of life outcomes when compared to a second type of…
- Conditions
- HIV, Food Insecurity, Malnutrition
- Trial name
- NCT02095613
- Testing
- traditional food, food that is nutrient dense
- Where
- Haiti
- Volunteers
- 623 people
- Sponsor
- Brigham and Women's Hospital
Iron Deficiency
Iron Absorption in Haiti
The government of Haiti plans to introduce a flour fortification program. The aim of the project it to inform the authorities on the most suitable iron compound for this fortification program.
- Trial name
- NCT02096250
- Testing
- NaFeEDTA, Ferrous fumarate, NaFeEDTA + ferrous fumarate
- Where
- Haiti
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Vitamin D Deficiency, Iodine Deficiency
Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children.
Vitamin D deficiency is common worldwide, including in infants and children, and rickets remains a public health concern in many developing countries.
- Conditions
- Vitamin D Deficiency, Iodine Deficiency, Hypothyroidism, Rickets
- Trial name
- Haiti (NCT02301520)
- Where
- 2 sites in Haiti
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
HIV Infections
Assessing HIV-Related Oral Mucosal Disease and Using Saliva to Measure Viral Load
The mouth may play an important part in monitoring HIV progression. Mucosal lesions of the mouth are often the first sign of infection and their development in already diagnosed individuals indicates disease progression.
- Trial name
- NCT00959413
- Where
- 6 sites in United States, Haiti
- Volunteers
- 328 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV Infections, Tuberculosis
Early Versus Standard Start of Anti-HIV Therapy for Treatment-Naive Adults in Haiti
Anti-HIV treatment consisting of lamivudine/zidovudine (3TC/ZDV) and efavirenz (EFV) is the current standard of care for initial treatment of HIV in most areas of the world.
- Trial name
- NCT00120510
- Testing
- Efavirenz, Lamivudine/Zidovudine
- Where
- Haiti
- Volunteers
- 816 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Risk Reduction Behavior, Interpersonal Relations
A Community-health Worker Delivered HIV/STI Prevention Intervention for Internally Displaced Women in Leogane, Haiti
The investigators will develop, deliver and evaluate a solar powered tablet-based individual and group focused HIV/STI prevention intervention with internally displaced women in Leogane, Haiti.
- Conditions
- Risk Reduction Behavior, Interpersonal Relations, Mental Disorders
- Trial name
- FASY (NCT01492829)
- Testing
- individual and group-based, community health worker delivered
- Where
- Haiti
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Wounds and Injuries, Traumatic Amputation
Monitoring and Treatment of Extremity Trauma for Mass Casualties in Difficult Contexts
The prospective cohort study, SuTra2, assesses the functional and socio-economic status of patients who were operated on for a severe limb injury resulting in amputation or limb preservation 1 and 2 years after the 2010 Haiti…
- Trial name
- SuTra² (NCT01779011)
- Where
- Haiti
- Volunteers
- 305 people
- Sponsor
- Alliance for International Medical Action
HIV Infections
A Study to Prepare for Future HIV Vaccine Studies
The purpose of this study is to determine the ability of HVTN sites to recruit and retain people at risk for HIV infection for possible future HIV vaccine research studies.
- Trial name
- NCT00029744
- Where
- 2 sites in Haiti, Peru
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Malnutrition
Effectiveness of Targeting Food Aid to Malnourished Children Compared to Targeting All Children Under Two Years
The objective of this study is to compare two approaches to targeting donated supplementary food to young children. The study compares the effectiveness of the widely-used curative approach where targeting is based on the child's…
- Trial name
- NCT00210418
- Testing
- Fortified food rations, Education and communication to improve feeding practices
- Where
- Haiti
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Anemia
Feasibility and Effectiveness of Distributing Micronutrient Sprinkles to Reduce Prevalence of Anemia
The objective of this study is to test the feasibility and effectiveness of distributing micronutrient sprinkles to 6-20 month old children participating in an integrated maternal and child health and nutrition program in rural…
- Trial name
- NCT00210405
- Testing
- "Sprinkles" containing mulitple micronutrients, Education/communication on use of micronutrient sprinkles, Fortified food aid (corn-soy blend)
- Where
- Haiti
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Lack of; Care, Infant (Child), Malnutrition
Evaluation of an Infant Feeding Intervention for HIV-exposed Haitian Infants
The purpose of this quasi-experimental study is to evaluate the effectiveness of an infant feeding intervention in improving growth and anemia outcomes among HIV-exposed infants 6-12 months of age.
- Trial name
- NCT01434238
- Testing
- Counseling and nutrition supplement
- Where
- Haiti
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cornell University
Lymphedema, Cellulitis
Evaluation of Antibacterial Soap for Treatment of Lymphedema in a Filariasis-Endemic Area
Introduction. Lymphatic filariasis is a devastating mosquito-transmitted parasitic disease that causes lymphedema or elephantiasis of the leg in 15 million persons, the majority of whom are women.
- Trial name
- NCT00139100
- Testing
- antimicrobial agent in soap
- Where
- Haiti
- Volunteers
- 200 people
- Sponsor
- Centers for Disease Control and Prevention