Clinical trials: in India
Carcinoma, Non-Small-Cell Lung
A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients
This is a Phase III, randomised, double-blind, placebo-controlled, multicentre study assessing the efficacy and safety of durvalumab compared with placebo, as consolidation therapy in patients with locally advanced, unresectable…
- Trial name
- PACIFIC-5 (NCT03706690)
- Testing
- Durvalumab
- Where
- 87 sites in China, Hong Kong and 8 more
- Volunteers
- 407 people
- Sponsor
- AstraZeneca
Plaque Induced Gingivitis
Clinical Safety and Efficacy Study of Water Flosser in Enhancing Oral Health Among Healthy Adults Having Plaque-induced Gingivitis and Dental Plaque Accumulation
This is a double-blind, randomized, control-arm clinical study to evaluate safety and efficacy of test water flosser in enhancing oral health among healthy adults having plaque-induced gingivitis and dental plaque accumulation.
- Trial name
- NCT07204951
- Testing
- Gurunanda - Water Flosser, No water Flossing
- Where
- India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Ulcerative Proctitis
Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories
A randomized, multi-center, double-blind, three arm placebo-controlled study in male and non-pregnant, non-lactating female subjects aged 18 years to examine the safety and efficacy of two dosing regimens of hydrocortisone…
- Trial name
- NCT04469686
- Testing
- Twice daily 90 mg hydrocortisone acetate suppository administered with Sephure applicator
- Where
- 189 sites in United States, Bulgaria and 21 more
- Volunteers
- 200 people
- Sponsor
- Cristcot HCA LLC
Type2 Diabetes Mellitus
Clinical Study to Assess the Safety, Efficacy and In-Use Tolerability of Herbal-Based Sugar Support Effervescent Tablets in Type-2 Diabetes Mellitus Patients
This is a Proof-of-Science, exploratory, prospective, single-treatment, two-group, clinical safety, efficacy and tolerability study of herbal based Sugar support effervescent tablets on the patients with Type 2 Diabetes Mellitus.
- Trial name
- NCT06961019
- Testing
- Sugar support effervescent Tablets
- Where
- India
- Volunteers
- 14 people
- Sponsor
- NovoBliss Research Pvt Ltd
Dry and Sensitive Skin
Validation of Skin Instrumentation to Detect Ceramide-Driven Lipid Replenishment - Assessing Skin Glow, Hydration, Trans Epidermal Water Loss, Skin Surface Assessment, Sebum and Least-Reflection Factor.
This is a single-center, open-label, split-face, site-randomized validation study, NB250045-NB-V designed to establish and confirm the reliability, reproducibility, and sensitivity of various skin measurement methods.
- Trial name
- NCT07423325
- Testing
- Marketed Product - CeraVe Moisturizer
- Where
- India
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Post Liver Transplant Infection
Effect of Preoperative Vitamin D Supplementation in Liver Transplant Recipients With Vitamin D Deficiency on Post Transplant Outcomes
Liver transplantation (LT) remains the ultimate option to cure intractable end stage liver disease. Vitamin D deficiency is very common in these subsets of patients.
- Trial name
- NCT06736093
- Testing
- Vitamin D3
- Where
- India
- Volunteers
- 140 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Atopic Dermatitis
A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis
The reason for this study is to see if the study drug called baricitinib works and is safe in children and teenage participants with atopic dermatitis.
- Trial name
- BREEZE-AD-PEDS (NCT03952559)
- Testing
- Baricitinib, Topical corticosteroid
- Where
- 78 sites in Argentina, Australia and 15 more
- Volunteers
- 516 people
- Sponsor
- Eli Lilly and Company
Kidney Stones, Urolithiasis
DISON I - Directly Integrated Suction and Optics System for the Treatment of Nephrolithiasis
A single-arm, multicenter, international, prospective interventional study designed to evaluate the safety and performance of an investigational device during retrograde intrarenal surgery for the treatment of renal calculi.
- Conditions
- Kidney Stones, Urolithiasis, Nephrolithiasis
- Trial name
- DISON I (NCT07712861)
- Testing
- RIRS with Investigational Device
- Where
- 5 sites in Argentina, Canada and 3 more
- Volunteers
- 75 people
- Sponsor
- Ventaris Surgical Incorporated
Fine Lines, Wrinkles
A Clinical Study to Test the Safety and Effectiveness of Pinorox® for Improving Visible Signs of Facial Aging Such as Wrinkles, Fine Lines, and Dark Spots.
A Randomized, Double-Blind, Three-Arm, Prospective, Single-Center Clinical Study to Evaluate the Safety, Efficacy, and Tolerability of Pinorox® in Subjects with Facial Signs of Aging
- Conditions
- Fine Lines, Wrinkles, Facial Sign of Aging
- Trial name
- NCT07111156
- Testing
- Topical Cream containing 0.1% Pinorox®, Topical Cream containing 1% Pinorox®
- Where
- India
- Volunteers
- 81 people
- Sponsor
- NovoBliss Research Pvt Ltd
Atopic Dermatitis (AD)
Exploratory Clinical Investigation on Neurosensory Responses Via EEG Headband in Adults With Mild to Moderate Atopic Dermatitis After Application of Marketed Product Compared With Placebo (Water Application).
This is a prospective, exploratory, double-blind, single-visit internal validation study designed to evaluate neurosensory responses using electroencephalography head band (EEG) in adult subjects with mild to moderate atopic…
- Trial name
- NCT07333300
- Testing
- Marketed Test Product
- Where
- India
- Volunteers
- 20 people
- Sponsor
- NovoBliss Research Pvt Ltd
Idiopathic Pulmonary Fibrosis
Randomized, Double-blind Study of Efficacy and Safety of Bexotegrast (PLN-74809) for Idiopathic Pulmonary Fibrosis
A randomized, double-blind, dose-ranging, placebo-controlled study to evaluate the efficacy and safety of bexotegrast (PLN-74809) for the treatment of idiopathic pulmonary fibrosis (BEACON-IPF).
- Trial name
- NCT06097260
- Testing
- PLN-74809
- Where
- 268 sites in United States, Argentina and 23 more
- Volunteers
- 320 people
- Sponsor
- Pliant Therapeutics, Inc.
Hypertension, Diabete Mellitus
Assessing the Effectiveness of Large Language Model (LLM)-Enabled Nurse Treatment Planning in 2 Indian Districts
The goal of this clinical trial is to learn whether AI-enabled, nurse-led treatment planning can improve the quality of clinical reasoning and management compared with standard physician-led care in adult primary care patients…
- Conditions
- Hypertension, Diabete Mellitus, Breathlessness, Fever
- Trial name
- NCT07432893
- Testing
- AI-enabled clinical decision support tool (software) used by nurses, Physician consultation
- Where
- 2 sites in India
- Volunteers
- 736 people
- Sponsor
- Sarah Nabia
Gingiival Hyperpigmentation
Comparison of Gingival Depigmentation Using Microneedling and Microneedling With Glutathione Gel - A Split Mouth Clinical Trial
The colour of gingiva is important determinant of smile esthetics.Owing to increasing awareness and demand for cosmetic procedures over the past decade, gingival depigmentation has gained popularity among periodontal plastic…
- Trial name
- NCT07748507
- Testing
- Microneedling using Dermapen device, Microneedling with 0.5 % Glutathione gel
- Where
- India
- Volunteers
- 15 people
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Acute Pancreatitis
A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis
The goal of this clinical trial is to test the safety and effectiveness of a single dose of RABI-767 given by endoscopic ultrasound (EUS) guided peripancreatic injection in participants with predicted severe acute pancreatitis.
- Trial name
- NCT06080789
- Testing
- RABI-767
- Where
- 16 sites in United States, India
- Volunteers
- 36 people
- Sponsor
- Panafina, Inc.
Glycogen Storage Diseases
'Glycogen Storage Diseases (GSDs) in Indian Children- Establishing an Indian GSD (I-GSD) Registry'
Glycogen storage disorders (GSD) are a class of inborn metabolic abnormalities characterized by enzymatic defects in glycogen production or breakdown and are one of commonest metabolic disorders of the childhood.
- Trial name
- I-GSD (NCT06396546)
- Where
- 37 sites in India
- Volunteers
- 250 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Child Diarrhea
What Drives Poor Care for Child Diarrhea: A Standardized Patient Experiment
Diarrhea is the second leading cause of death for children around the world, although nearly all of these deaths could be prevented with an inexpensive and simple treatment: oral rehydration salts (ORS).
- Trial name
- NCT04833790
- Testing
- Free distribution of ORS, Standardized patient with ORS preference, Standardized patient with Antibiotic preference
- Where
- India
- Volunteers
- 2,451 people, healthy volunteers welcome
- Sponsor
- RAND
Oral Cavity Squamous Cell Carcinoma
Study Comparing Limited and Extensive Neck Surgery in Oral Cancer Patients With Neck Spread
Oral cavity squamous cell carcinoma (OCSCC) frequently metastasizes to cervical lymph nodes, and the extent of neck dissection remains an area of ongoing debate in patients with clinically node-positive (cN1) disease.
- Trial name
- ExtentN1 (NCT07717307)
- Testing
- Selective Neck Dissection (Levels I-IV), Modified Neck Dissection (Levels I-V)
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Kolhapur Cancer Centre - Cancer Centers of America
Type 2 Diabetes Mellitus
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin
The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron compared with placebo in adults with Type 2 Diabetes Mellitus (T2DM), treated with a background insulin and other background…
- Trial name
- Eluminate-3 (NCT07664553)
- Testing
- Elecoglipron
- Where
- 132 sites in United States, Australia and 11 more
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Oral Squamous Cell Carcinoma (OSCC)
Study Comparing Different Neck Treatment Approaches in Patients With Oral Cancer Without Visible Neck Spread
The goal of this clinical trial is to learn whether selective neck dissection involving lymph node levels I-III is as effective as selective neck dissection involving levels I-IV in treating adults with clinically node-negative…
- Trial name
- ExtentN0 (NCT07726199)
- Testing
- Selective Neck Dissection (Levels I-IV), Intervention : Selective Neck Dissection (Levels I-III)
- Where
- India
- Volunteers
- 267 people
- Sponsor
- Kolhapur Cancer Centre - Cancer Centers of America
Chronic Migraine Headache, Chronic Migraine, Headache
EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) OF PRIMARY MOTOR CORTEX ON HEADACHE FREQUENCY IN PATIENTS WITH CHRONIC MIGRAINE
Migraine is a common, heterogeneous neurological disorder affecting approximately 10-15% of the global population and is the third most prevalent disease worldwide.
- Trial name
- NCT07743814
- Testing
- Transcranial Direct Current stimulation
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Dr. Ram Manohar Lohia Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.