Clinical trials: in India
Tissue Adhesives
Quantifying Adhesive Residue on Skin Following Removal of Maxillofacial Prosthetic Adhesives: An In Vivo Study
This pilot interventional in vivo study aims to quantitatively evaluate and compare the amount of adhesive residue left on the skin following removal of extraoral maxillofacial prosthetic adhesives.
- Trial name
- ARMS (NCT07647458)
- Testing
- Secure Adhesive Regular,, Secure Adhesive Extra Strength, Daro Adhesive Regular
- Where
- India
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Amrita Vishwa Vidyapeetham
Peri-implant Soft Tissue Healing
Comparison of Freeze-Dried Amniotic and Collagen Membranes for Soft Tissue Healing After Grafted Implant Surgery
The goal of this clinical trial is to learn whether Freeze-Dried Amniotic Membrane (FD-AM) or Collagen Membrane (CM) provides better soft tissue healing after Stage I dental implant surgery with particulate bone grafting in…
- Trial name
- FDAM-CM (NCT07647120)
- Testing
- Freeze-Dried Amniotic Membrane (FD-AM), Collagen Membrane (CM)
- Where
- India
- Volunteers
- 10 people
- Sponsor
- RAJAS DENTAL COLLEGE AND HOSPITAL
Tuberculosis, HIV
Alcohol Reduction Among People With TB and HIV in India
The highest incidence of tuberculosis disease (TB) in the world is in India, accounting for 27% of all new cases globally, with approximately 86,000 among persons with HIV (PWH).
- Trial name
- HATHI (NCT04230395)
- Testing
- HATHI Intervention, Usual Care
- Where
- 2 sites in India
- Volunteers
- 450 people
- Sponsor
- Johns Hopkins University
Anemia, Anemia, Postpartum
Comparative Analysis of Oral Iron With Injectable Ferric Carboxymaltose for Post Partum Iron Deficiency Anaemia
The aim of this open label, interventional, randomized controlled clinical trial is to compare the efficacy and safety of ferric carboxymaltose injection with oral iron in treatment of postpartum iron deficiency anaemia in…
- Conditions
- Anemia, Anemia, Postpartum, Iron Deficiency Anemia of Pregnancy, Iron Deficiency Anemia Treatment
- Trial name
- NCT07648628
- Testing
- Ferric Carboxymaltose (FCM)
- Where
- India
- Volunteers
- 200 people
- Sponsor
- ESI-PGIMSR, Basaidarapur
Primary Immune Thrombocytopenia (ITP)
Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)
The purpose of this study is to evaluate the effect of two different doses of ianalumab versus placebo in addition to first-line corticosteroids in increasing the rate of stable response off treatment at 12 months (SROT-12) in…
- Trial name
- VAYHIT1 (NCT05653349)
- Testing
- Ianalumab, Corticosteroids
- Where
- 111 sites in United States, Argentina and 23 more
- Volunteers
- 226 people
- Sponsor
- Novartis Pharmaceuticals
Pancreas Disease
A COMBINATION OF RECTAL INDOMETHACIN AND COLD WATER EXPOSURE OF THE AMPULLA AFTER ERCP IS SUPERIOR TO RECTAL INDOMETHACIN ALONE IN REDUCING THE INCIDENCE OF POST-ERCP PANCREATITIS -RCT
Endoscopic retrograde cholangiopancreatography (ERCP) has emerged as the primary modality in the management of biliary and pancreatic disease. The complications occurring from ERCP can range from mild to fatal.
- Trial name
- ERCP (NCT07574970)
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Asian Institute of Gastroenterology, India
Gingival Recession
Effect Of Microneedling With Coronally Advanced Flap For Management of RT1 Gingival Recession In Thin Gingival Phenotype
The goal of this clinical trial is to explore the effect of microneedling to increase the gingival tissue thickness which could improve the outcome of root coverage in coronally advanced flap procedure in thin gingival phenotype.
- Trial name
- RT1 (NCT06988839)
- Testing
- Microneedling followed by coronally advanced flap, Coronally advanced flap with connective tissue graft
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Diabetes Mellitus, Type 2, Liver Diseases
Validate Smart Breath Analyzer as Screening Tool for Diabetic, Hepatic, Renal, Lung, and Other Metabolic Disorders
This is a prospective, multicentric, non-treatment study to build and validate a portable, non-invasive smart breath analyzer that can screen underlying health issues using exhaled breath.
- Conditions
- Diabetes Mellitus, Type 2, Liver Diseases, Kidney Diseases, Lung Diseases
- Trial name
- RESPYR-SBA (NCT07646015)
- Where
- India
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Respyr
Autoimmune Hepatitis
Host-Diet-Gut Interaction Post Vegan Diet in Pediatric Autoimmune Hepatitis.
Pediatric autoimmune liver diseases (AILDs), including autoimmune hepatitis (AIH) and overlap syndromes like sclerosing cholangitis, are among the most common chronic liver conditions in the pediatric population.
- Trial name
- NCT07118657
- Testing
- Vegan Diet, Standard Diet
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
SGA, Turner Syndrome, Noonan Syndrome, ISS
A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow
The study compares two medicines for treatment of children born small and who stay small, or with Turner Syndrome, Noonan Syndrome, or idiopathic short stature.
- Trial name
- REAL 8 (NCT05330325)
- Testing
- Somapacitan, Norditropin®
- Where
- 199 sites in United States, Austria and 31 more
- Volunteers
- 412 people
- Sponsor
- Novo Nordisk A/S
Furcation Defects
Effect of Mobile Health on Plaque Control Efficacy in Molars With Furcation Involvement
Furcation involvement (FI) refers to a condition in which the progression of the periodontal disease process invades the bifurcation and trifurcation of multirooted teeth.
- Trial name
- NCT07642895
- Testing
- Behavioural text messages twice weekly, Standardized oral hygiene instructions
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Open Angle Glaucoma, Ocular Hypertension
MINIject Global Long-Term Follow-up Study
The study will assess the long-term (up to 5 years) safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.
- Trial name
- STAR-GLOBAL (NCT04524416)
- Testing
- Minimally invasive glaucoma surgery (MIGS)
- Where
- 9 sites in Colombia, France and 4 more
- Volunteers
- 116 people
- Sponsor
- iSTAR Medical
Pregnancy, High Risk
PRISMA Maternal and Newborn Health Study
Access to quality antenatal care (ANC) and postnatal care (PNC), including maternal, newborn, and infant services, is integral to reducing adverse pregnancy-related health outcomes and promoting positive birth experiences.
- Trial name
- PRiSMA-MNH (NCT05904145)
- Where
- 5 sites in Ghana, India and 3 more
- Volunteers
- 267,897 people, healthy volunteers welcome
- Sponsor
- George Washington University
Neoplasms
A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer
The purpose of this study is to evaluate two study medicines (encorafenib plus cetuximab) taken alone or together with standard chemotherapy for the potential treatment of colorectal cancer that: has spread to other parts of the…
- Trial name
- NCT04607421
- Testing
- Encorafenib, Cetuximab, Oxaliplatin
- Where
- 272 sites in United States, Argentina and 27 more
- Volunteers
- 841 people
- Sponsor
- Pfizer
Post Endodontic Pain
Comparative Evaluation of Transdermal and Oral Drugs for Management of Post-Endodontic Pain
This clinical trial evaluated whether two drugs delivered through transdermal drug delivery systems reduced post-endodontic pain as effectively as two orally administered medications in adult patients undergoing root canal…
- Trial name
- PATCH-PAIN (NCT07610265)
- Testing
- Ketoprofen transdermal patch, Fentanyl transdermal patch, Diclofenac sodium tablet
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Nims University Rajasthan
Reversible Pulpitis, Extremely Deep Caries
Influence of Proximal Caries on Outcome of Direct Pulp Capping in Permanent Mandibular Molars With Reversible Pulpitis
The aim of the study is to assess the Influence of proximal caries on outcome of direct pulp capping in permanent mandibular molars with sign of reversible pulpitis.
- Trial name
- NCT07578662
- Testing
- Direct pulp capping in proximal carious lesion, Direct pulp capping in occlusal carious lesion
- Where
- India
- Volunteers
- 154 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Neuropathy, Oncology
Exercise Intervention for Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect of chemotherapy that can negatively impact patients' functional status and quality of life.
- Conditions
- Neuropathy, Oncology, Exercise, Effectiveness
- Trial name
- NCT07635901
- Testing
- Structured exercise program for CIPN
- Where
- India
- Volunteers
- 282 people
- Sponsor
- Sri Ramachandra Institute of Higher Education and Research
Periodontal Disease
Mental Health and Periodontitis in Probable Bruxers
The goal of this observational study is to learn how mental health affects periodontal health in people having teeth grinding (bruxism).
- Trial name
- NCT07634250
- Where
- India
- Volunteers
- 110 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Low Back Pain
F-18 Sodium Fluoride PET/CT Guided Versus Ultrasound- Guided Intra-articular Injections in Chronic Low Backache
The goal of this open-label randomized controlled trial explored the efficacy of ultrasound guided versus F-18 Sodium Fluoride PET/CT guided local anesthetic and steroid injections in managing chronic low back pain caused by…
- Trial name
- PET-FACET (NCT07632508)
- Testing
- intra-articular injection
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Esophageal Motility Disorders
Monopolar and Bipolar Current RFA Knife in POEM
Per Oral Endoscopic Myotomy (POEM) is performed for various esophageal muscular disorders, including achalasia and other spastic esophageal conditions.
- Trial name
- NCT05272046
- Testing
- Per-oral Endoscopic Myotomy, Speedboat (Bipolar electrocautery knife)
- Where
- 3 sites in United States, India and 1 more
- Volunteers
- 104 people
- Sponsor
- Baylor College of Medicine
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