Clinical trials: in Iran
Attention Deficit Disorder With Hyperactivity, Neurodevelopmental Disorders
tES Modalities for the Treatment of ADHD
This project investigates the efficacy of transcranial electrical stimulation (tES) modalities, specifically transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), for treating…
- Trial name
- NCT06974136
- Testing
- transcranial electrical stimulation
- Where
- Iran
- Volunteers
- 45 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD)
The Effects of 5-methyltetrahydrofolate Supplementation in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease
To determine the effect of MTHF supplementation on serum folate and homocysteine level, metabolic, nutritional status, liver function, and PPARα and TNFα gene expression in patients with MASLD
- Conditions
- Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD), MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD
- Trial name
- MASLD (NCT07740109)
- Testing
- 5-methyltetrahydrofolate (5-MTHF)
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- Tabriz University of Medical Sciences
Bone Fractures
Naringenin Supplementation in Bone Fracture Patients
Fractures of the lower extremities represent a significant proportion of injuries sustained by polytrauma patients, with a notable association with prolonged hospitalization, chronic disability, and impaired physical functioning.
- Trial name
- NCT06612762
- Testing
- The daily ingestion of capsules containing naringenin
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Healthy Volunteers
Effects of Breath-Hold vs Standard Interval Training on Fitness in Mountaineers
This study investigated whether adding structured breath-holds to standard interval training improves cardiorespiratory fitness in recreational mountaineers more than interval training alone.
- Trial name
- NCT07703839
- Testing
- Voluntary Hypoventilation Training, Progressive Treadmill Interval Training
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohammadreza Rezaeipour, MD, PhD
Hepatocellular Carcinoma (HCC)
Safety and Feasibility of CIK Cell Therapy in HCC After Tumor Resection
This study tests whether it is safe and feasible to give patients with hepatocellular carcinoma (liver cancer) an infusion of their own (autologous) immune cells, called cytokine-induced killer (CIK) cells, after they have had…
- Trial name
- NCT07709299
- Testing
- Autologous Cytokine-Induced Killer (CIK) Cells
- Where
- Iran
- Volunteers
- 6 people
- Sponsor
- Royan Institute
Premature Ovarian Failure
Intra-ovarian Injection of MSC-EVs in Idiopathic Premature Ovarian Failure
Premature ovarian failure (POF) is a clinical syndrome defined by loss of ovarian activity before the age of 40 years. POF is characterized by menstrual disturbance (amenorrhea or oligomenorrhea) with raised gonadotrophins and…
- Trial name
- NCT06202547
- Testing
- Intra-ovarian injection of bone marrow mesenchymal stromal cells-derived extracellular vesicles
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Royan Institute
Obesity & Overweight
Spartina® (Tirzepatide) Effectiveness and Safety Evaluation
The goal of this study is to evaluate Effectiveness and safety of Spartina® (Tirzepatide) in male or female participants with obesity and overweight. The main questions which are aimed to be answered: 1.
- Trial name
- NCT07262762
- Where
- 14 sites in Iran
- Volunteers
- 175 people
- Sponsor
- Cinnagen
Insomnia, Insomnia Disorder
Rumination-Tailored Guided Internet-Based CBT-I for University Students
The goal of this clinical trial is to evaluate whether adding rumination-tailored, rule-based personalized feedback to guided internet-based cognitive behavioral therapy for insomnia (iCBT-I) improves treatment outcomes in…
- Trial name
- RUM-CBTI (NCT07623889)
- Testing
- Guided Internet-Based Cognitive Behavioral Therapy for Insomnia (iCBT-I), Rumination-Tailored Rule-Based Personalized Feedback
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Proximal Femoral Fracture, Dinamic Hip Surgery
Motion Graphic Training for Scrub Nurses in Hip Surgery
This pilot randomized controlled trial evaluates the effect of motion graphic video-based training on the performance of scrub nurse students during dynamic hip screw (DHS) surgery.
- Trial name
- NCT07701564
- Testing
- Motion Graphic Video Training, Routine Clinical Training
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Denture Stomatitis, Chronic Atrophic Candidiasis
Efficacy of 1% Nanochitosan Solution in the Treatment of Denture Stomatitis
The purpose of this study is to evaluate and compare the clinical efficacy of a 1% nanochitosan solution versus a standard Nystatin oral suspension in patients diagnosed with Newton's type II denture stomatitis (chronic atrophic…
- Trial name
- NCT07694024
- Testing
- 1% Nanochitosan Solution, Nystatin Oral Suspension
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Kerman University of Medical Sciences
Parkinson Disease
Aquatic High-Intensity Interval Training for Parkinson's Disease
This randomized, single-center, parallel-group superiority trial will evaluate the effect of an 8-week aquatic High-Intensity Interval Training (HIIT) program on balance, physical function, and sarcopenia-related outcomes in…
- Trial name
- NCT07264114
- Testing
- Aquatic HIIT with adherence/support package
- Where
- Iran
- Volunteers
- 56 people
- Sponsor
- Pardis Specialized Wellness Institute
Idiopathic Oligoasthenoteratozoospermia, Male Infertility
Comparative Evaluation of the Efficacy of Letrozole, L-Carnitine, and Their Combination on Sperm Quality, Oxidative Stress, and ART Outcomes in Men With Idiopathic Oligoasthenoteratozoospermia.
This is a randomized clinical trial evaluating the efficacy of Letrozole, L-Carnitine, and their combination on sperm quality, oxidative stress, and ART outcomes in men with idiopathic oligoasthenoteratozoospermia.
- Trial name
- NCT07669402
- Testing
- Letrozole 2.5mg, L-carnitine
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Tehran University of Medical Sciences
Athletic Performance, Physical Endurance
Event-Specific Adaptations to CrossFit and Running-Based HIIT in Elite Distance Runners at Moderate Altitude
The goal of this clinical trial is to compare the effects of two high-intensity training programs on physical performance and physiological adaptations in elite male middle- and long-distance runners aged 25 to 35 years who live…
- Conditions
- Athletic Performance, Physical Endurance, Altitude Training Adaptation, Aerobic Capacity
- Trial name
- NCT07675577
- Testing
- Running-Based High-Intensity Interval Training (HIIT), CrossFit-Based High-Intensity Training (CF)
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Brain Tumor, Grade III Glioma
Safety and Effectiveness Evaluation of Temozolomide (Amitzo, NanoAlvand) in Patients With Grade III and IV Glioma Tumors
This is a phase IV, post-marketing, observational, cohort study for safety and effectiveness evaluation of Amitzo® in Iranian patients with grade III and IV glioma tumors. No control group is considered in the study design.
- Conditions
- Brain Tumor, Grade III Glioma, Grade IV Glioma
- Trial name
- NCT07675070
- Testing
- temozolomide
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- NanoAlvand
Abuse, Mindfulness
Mindfulness-Art Therapy Intervention in Abused Adolescents
Adolescence is an important stage of development when many mental health difficulties first appear. Young people who have experienced abuse are especially vulnerable, as abuse can lead to intense feelings of shame and negatively…
- Conditions
- Abuse, Mindfulness, Art Therapy
- Trial name
- NCT07674056
- Testing
- Mindfulness and Art Therapy Group Program
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Ardakan University
Foster Care
Effectiveness of MBT-C Among Foster Children
This study examined whether Mentalization-Based Treatment for Children (MBT-C) could improve emotion regulation and emotional awareness among children in foster care.
- Trial name
- NCT07674017
- Testing
- Mentalization-based treatment for children
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Ardakan University
Dental Caries, Bleeding on Probing
Evaluating Methods of Dental Health Instructions on the Oral Health Indices of 12-18-year-old Patients With Fixed Orthodontics
The goal of this clinical trial is to learn which type of oral health education works best to help 12-18-year-old participants with fixed orthodontic appliances (braces) keep their mouths healthy.
- Conditions
- Dental Caries, Bleeding on Probing, Gingival Index, Plaque Index
- Trial name
- NCT07667283
- Testing
- Verbal Oral Hygiene Instruction, Pamphlet-Based Oral Hygiene Instruction, Video-Based Oral Hygiene Instruction
- Where
- Iran
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Overweight (BMI > 25), Obesity (BMI>30)
Combined Training (Strength and Endurance) and the Serum Levels of Myostatin and Hormone-sensitive Lipase in Overweight and Obese Men
This randomized controlled trial investigated the effects of upper body-based and lower body-based combined training on serum levels of myostatin (MSTN) and hormone-sensitive lipase (HSL) in overweight and obese men.
- Trial name
- NCT07658261
- Testing
- Upper Body Combined Training, Lower Body Combined Training
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Arya Habibi
Medical Education
The Differential Impact of High-Stakes Versus Routine OSCE Stations on Nursing Students' Stress Levels and Clinical Competency: An Experimental Study
Abstract Background: Objective Structured Clinical Examinations (OSCEs) are vital for assessing nursing competence. However, the design of OSCE stations, particularly comparing critical (high-stakes) versus routine (low-stakes)…
- Trial name
- NCT07656506
- Testing
- High-Stake OSCE
- Where
- Iran
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Torbat Heydariyeh University of Medical Sciences
Cancer Recurrence
Group Positive Psychology-Based Program for Fear of Breast Cancer Recurrence
The goal of this clinical trial is to learn whether a group positive psychology-based educational program can reduce fear of cancer recurrence in women with a history of breast cancer who have completed primary treatment…
- Trial name
- NCT07657728
- Testing
- Positive Psychology-Based Educational Program
- Where
- Iran
- Volunteers
- 38 people
- Sponsor
- Golestan University of Medical sciences