Clinical trials: active, in Iran
Knowledge, Satisfaction
Comparing the Effect of Scenario-Based Teaching Method to Conventional Method on Medical Students' Knowledge and Satisfaction in Psychiatry Interns
Traditional medical education methods, which rely heavily on lectures and textbook study, have come under criticism for their inability to foster the critical thinking, clinical reasoning, and practical skills required to manage…
- Trial name
- NCT07885670
- Testing
- scenario-based teaching method
- Where
- Iran
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Psychological Stress, Perceived Stress
A Persian AI-Based CBT Chatbot and Voice Analysis System for Managing Perceived Stress
This pilot randomized controlled trial aims to evaluate a Persian-language artificial intelligence (AI)-based cognitive behavioral therapy (CBT) chatbot designed to support adults in managing perceived stress.
- Trial name
- PersianAI-CBT (NCT07840469)
- Testing
- Persian AI-Based CBT Chatbot, Active Mental Health Content
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Hamid Reza Marateb
Venous Thromboembolism
Computerized Registry of Patients With Venous Thromboembolism (RIETE)
The Computerized Registry of Patients with Venous Thromboembolism (RIETE) is a multidisciplinary Project initiated in march 2001 and consisting in obtaining an extensive data registry of consecutive patients with venous…
- Trial name
- RIETE (NCT02832245)
- Where
- 305 sites in United States, Argentina and 27 more
- Volunteers
- 120,000 people
- Sponsor
- Manuel Monreal
Cancer, Metastatic Cancer
Transarterial Chemoembolization (TACE) Plus Bevacizumab for Liver Metastases
Trans arterial chemoembolization (TACE) has emerged as a treatment option for chemotherapy-refractory diseases in Liver metastases.
- Conditions
- Cancer, Metastatic Cancer, Liver Metastases
- Trial name
- NCT06311851
- Testing
- Bevacizumab
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Pardis Noor Medical Imaging and Cancer Center
Parkinson Disease
The Effect of Eye Exercises in Parkinson's Disease
Parkinson's disease is commonly associated with impaired gait, postural instability, reduced physical function, and increased concern about falling, all of which contribute substantially to disability and reduced quality of life.
- Trial name
- NCT07525973
- Testing
- Supervised In-Center Eye Exercises
- Where
- Iran
- Volunteers
- 68 people
- Sponsor
- Pardis Specialized Wellness Institute
Chronic Kidney Disease (Stages 3b-5)
Pistachio Consumption in Patients With Chronic Kidney Disease
Standard chronic kidney disease (CKD) guidelines frequently restrict nut intake due to concerns regarding their phosphorus and potassium content.
- Trial name
- NCT07815600
- Testing
- Pistachio, Control
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Perimembranous Ventricular Septal Defect
An International Multicenter Study on Transcatheter Device Closure of Perimembranous Ventricular Septal Defects
The international multicenter registry aims to gather real-world data on patient outcomes and assess the procedural success and performance of various device occluders used in the transcatheter treatment of pediatric and adult…
- Trial name
- PERI-CLOSE (NCT06823635)
- Testing
- Transcatheter device closure of perimembranous ventricular septal defects (PmVSDs)
- Where
- 25 sites in Denmark, Egypt and 15 more
- Volunteers
- 2,000 people
- Sponsor
- Fondation Hôpital Saint-Joseph
End-Stage Renal Disease, Hemodialysis Complication
The Effect of Intradialytic Exercise on Postural Abnormalities
This randomized, assessor-blinded controlled trial will evaluate the preliminary efficacy and safety of a 12-week supervised intradialytic multimodal exercise program for improving postural abnormalities in adults receiving…
- Trial name
- NCT07720401
- Testing
- Supervised Intradialytic Multimodal Exercise Program
- Where
- Iran
- Volunteers
- 98 people
- Sponsor
- Pardis Specialized Wellness Institute
End Stage Renal Disease, Hemodialysis Complication
The Effect of Intradialytic Eye Exercise in Hemodialysis Patients
This pilot randomized trial will evaluate whether a structured intradialytic eye-exercise program can be delivered safely and consistently during maintenance hemodialysis and whether it shows preliminary promise for improving…
- Trial name
- NCT07591714
- Testing
- Intradialytic Eye Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
Hemophilia A, Hemophilia
Prevalence of Inhibitor Development in Hemophilia A Patients Receiving Coageight: A Multicenter Cross-sectional Observational Study
This is a cross-sectional, observational, multi-center study to assess the prevalence of inhibitor development in hemophilia A patients receiving Coageight (rFVIII-Fc, AryoGen Pharmed Co.).
- Trial name
- NCT07791836
- Testing
- efmoroctocog alfa
- Where
- 6 sites in Iran
- Volunteers
- 262 people
- Sponsor
- AryoGen Pharmed Co.
Obesity & Overweight
EMS vs. Resistance Training in Overweight Women
This study aims to compare the effects of eight weeks of resistance training versus electrical muscle stimulation (EMS) on oxidative stress indicators and cellular health index in overweight and obese women aged 35-45 years.
- Trial name
- NCT07787286
- Testing
- Resistance Training, Electrical Muscle Stimulation, No Intervention
- Where
- Iran
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Birjand University of Medical Sciences
Developmental Dyslexia
Brain Stimulation With Combined Reading and Motor Training for Children With Dyslexia
This study examines whether combining non-invasive brain stimulation (tDCS) with an integrated reading-and-motor training program improves reading and phonological processing in 9-year-old boys with developmental dyslexia.
- Trial name
- NCT07781761
- Testing
- Active transcranial direct current stimulation (tDCS), Phonological awareness training, Non-targeted fine motor training
- Where
- Iran
- Volunteers
- 160 people
- Sponsor
- Shahid Beheshti University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
BPH Global Registry
Benign prostatic hyperplasia (BPH) is one of the most common performed surgical procedures in urology. Over the past few decades there have been an increasing development of newer surgical treatment options.
- Trial name
- NCT05543200
- Where
- 30 sites in United States, Canada and 19 more
- Volunteers
- 7,500 people
- Sponsor
- Société Internationale d'Urologie
Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD)
The Effects of 5-methyltetrahydrofolate Supplementation in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease
To determine the effect of MTHF supplementation on serum folate and homocysteine level, metabolic, nutritional status, liver function, and PPARα and TNFα gene expression in patients with MASLD
- Conditions
- Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD), MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD
- Trial name
- MASLD (NCT07740109)
- Testing
- 5-methyltetrahydrofolate (5-MTHF)
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- Tabriz University of Medical Sciences
Bone Fractures
Naringenin Supplementation in Bone Fracture Patients
Fractures of the lower extremities represent a significant proportion of injuries sustained by polytrauma patients, with a notable association with prolonged hospitalization, chronic disability, and impaired physical functioning.
- Trial name
- NCT06612762
- Testing
- The daily ingestion of capsules containing naringenin
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Hepatocellular Carcinoma (HCC)
Safety and Feasibility of CIK Cell Therapy in HCC After Tumor Resection
This study tests whether it is safe and feasible to give patients with hepatocellular carcinoma (liver cancer) an infusion of their own (autologous) immune cells, called cytokine-induced killer (CIK) cells, after they have had…
- Trial name
- NCT07709299
- Testing
- Autologous Cytokine-Induced Killer (CIK) Cells
- Where
- Iran
- Volunteers
- 6 people
- Sponsor
- Royan Institute
Insomnia, Insomnia Disorder
Rumination-Tailored Guided Internet-Based CBT-I for University Students
The goal of this clinical trial is to evaluate whether adding rumination-tailored, rule-based personalized feedback to guided internet-based cognitive behavioral therapy for insomnia (iCBT-I) improves treatment outcomes in…
- Trial name
- RUM-CBTI (NCT07623889)
- Testing
- Guided Internet-Based Cognitive Behavioral Therapy for Insomnia (iCBT-I), Rumination-Tailored Rule-Based Personalized Feedback
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Brain Tumor, Grade III Glioma
Safety and Effectiveness Evaluation of Temozolomide (Amitzo, NanoAlvand) in Patients With Grade III and IV Glioma Tumors
This is a phase IV, post-marketing, observational, cohort study for safety and effectiveness evaluation of Amitzo® in Iranian patients with grade III and IV glioma tumors. No control group is considered in the study design.
- Conditions
- Brain Tumor, Grade III Glioma, Grade IV Glioma
- Trial name
- NCT07675070
- Testing
- temozolomide
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- NanoAlvand
Parkinson Disease (PD)
Safety and Feasibility of Bilateral Striatal Transplantation of DopaCell in Parkinson's Disease
Dopason is a phase I, open-label, multicenter, single-arm clinical trial designed to evaluate the safety and feasibility of intraputaminal transplantation of human embryonic stem cell-derived dopaminergic progenitor cells…
- Trial name
- NCT07572071
- Testing
- Dopacell, Immunosuppressive Regimen, Customized microinjection device
- Where
- 3 sites in Iran
- Volunteers
- 6 people
- Sponsor
- Royan Institute
Acute Coronary Syndromes, Unstable Angina (UA)
Oregano and Basil Leaves and Coronary Artery Disease
The present study will examine the effects of increasing dietary polyphenol intake by consumption of oregano and basil leaves, on plasma inflammatory and lipid factors and total urinary polyphenol levels in patients who have…
- Trial name
- NCT07123181
- Testing
- Control (Standard treatment), Higher polyphenol intake by consumption of oregano and basil
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Shahid Beheshti University of Medical Sciences