Clinical trials: suspended, in Italy
Ductus Arteriosus Patent, Respiratory Distress Syndrome
Paracetamol vs Ibuprofen for PDA Closure in Preterm Infants.
Current pharmacological options to treat an hemodynamically significant PDA (HsPDA) in preterm infants are limited to non-selective cyclo-oxygenase (COX) inhibitors, indomethacin or ibuprofen.
- Trial name
- PARIDA (NCT02056223)
- Testing
- Intravenous paracetamol, Intravenous ibuprofen
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Padova
Post-operative Cognitive Dysfunction
Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly
BACKGROUND: Post-operative cognitive dysfunction (POCD) is a potentially irreversible loss of brain functions observed in elderly patients after surgical operations under general anaesthesia.
- Trial name
- THE BRIDGE (NCT02428062)
- Testing
- Hemodynamic target, Phenylephrine, Intravenous fluids
- Where
- Italy
- Volunteers
- 1,812 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Colonic Neoplasms
Utility Of Citogenex Administration In Patients With Colon-Rectal Cancer
The main aim of the present study is to test the efficacy and safety of CITOGENEX administration in patients with colon-rectal cancer.
- Trial name
- CITOGENEX PA (NCT01477866)
- Testing
- citogenex, conventional therapy
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- University of Palermo
Spasticity, Lokomat
Reliability of Spasticity Measurement With Lokomat
The purpose of the study is to evaluate the reliability of spasticity measurement with Lokomat
- Trial name
- NCT02718053
- Testing
- L-stiff, Ashworth
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Phobia Phlebotomy
Use of Local Warming in Children Venipuncture
The aim of this study is to determine if local application of heat increases the probability of insertion of peripheral venous catheter at the first attempt, reduces the time needed to obtain cannulation and maintains the…
- Trial name
- NCT01543009
- Testing
- Emla + Local Warming
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- University of Florence
Infection of Intravenous Catheter, Phlebitis
Normal Saline Versus Heparinized Solution Flush for Maintaining Patency of Peripheral Venous Catheters in Children
The aim of the study is to verify if the periodic flush with normal saline 0.9% NaCl causes a longer or equal duration of patency of peripheral venous catheters, compared with heparin solution 50 U / ml flush, in children from 2…
- Conditions
- Infection of Intravenous Catheter, Phlebitis, Extravasation of Diagnostic and Therapeutic Materials
- Trial name
- NCT01794767
- Testing
- 0,9% NaCl flush, Heparin 50U/ml
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Florence
Stroke, Acute
Comparative Study of GangTrainer GT1, Lokomat and Conventional Physiotherapy
The GangTrainer GT I and the Lokomat have proven their effectiveness on stroke Patients, but a comparison on the same controlled study population has not been made so far.
- Trial name
- galop (NCT01146587)
- Testing
- GangTrainer GT1, Lokomat, Conventional Physiotherapy
- Where
- 7 sites in Austria, Italy
- Volunteers
- 120 people
- Sponsor
- Research Department for Neurorehabilitation South Tyrol
Peripheral Arterial Disease
Drug Eluting Balloon in Peripheral Intervention for In-Stent Restenosis
The purpose of this study is to evaluate the efficacy of drug-eluting balloon angioplasty followed versus conventional balloon angioplasty in superficial femoral artery and popliteal artery re-stenosis.
- Trial name
- DEBATE-ISR (NCT01558531)
- Testing
- DEB, POBA
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Leonardo Bolognese, MD
Chronic Heart Failure
Treatment of the lOw IGF-1 Syndrome aSsociated With Chronic Heart fAilure: A Randomized, Placebo-Controlled, Double-Blind Study.
The objective of the study is to determine whether treatment of the low IGF-1 syndrome in patients with CHF is able to modify some functional parameters, recognized as valid surrogate end-points of CHF progression.
- Trial name
- TOSCA2 (NCT01235273)
- Testing
- Growth Hormone
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Chronic Pain
Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain
Aim of this project is to customize the choice of the strong opioid in the treatment of cancer chronic pain through the identification of patient clinical history and pain characteristics, moreover in the analysis the…
- Trial name
- NCT00916890
- Testing
- Morphine, Oxycodone, Fentanyl
- Where
- 6 sites in Italy
- Volunteers
- 320 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Polycystic Ovary Syndrome
Controlled Ovarian Stimulation Followed by Timed Intercourse or Intrauterine Insemination in Infertile PCOS Patients
At the present the first options to induce ovulation in polycystic ovary syndrome with anovulatory infertility are clomiphene citrate (CC) and metformin.
- Trial name
- NCT00502281
- Testing
- highly purified urinary FSH, timed intercourses, intrauterine insemination
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University Magna Graecia
Refractory Angina
Intramyocardial Delivery of Autologous Bone Marrow
A randomized study to assess the safety, feasibility and effectiveness of direct intramyocardial percutaneous delivery of autologous bone marrow-derived total mononuclear cells or selected CD34+ cells in patients with refractory…
- Trial name
- NCT00820586
- Testing
- Mononuclear bone marrow derived cells
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- IRCCS San Raffaele
Advanced Solid Tumors
Sorafenib in Combination With RAD001 in Advanced Solid Tumors Selected on Molecular Targets
Sorafenib is an oral multikinase inhibitor and among its targets are several RTKs involved in tumor genesis (Raf, Flt-3, c-Kit and RET) and angiogenesis (VEGFR1, 2 and 3 and PDGFRß).
- Trial name
- NCT01226056
- Testing
- RAD001 in combination with sorafenib
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Southern Europe New Drug Organization