Clinical trials: in Kenya
Bacterial Diseases, Other Mycoses
Reducing Vaginal Infections in Women
The purpose of this study is to see if taking medication once a month can help to decrease the risk of vaginal infections. Additionally, researchers will study whether personal habits, such as douching, bathing, and sexual…
- Conditions
- Bacterial Diseases, Other Mycoses, Sexually Transmitted Infection
- Trial name
- NCT00170430
- Testing
- Fluconazole, Metronizadole
- Where
- Kenya
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Malaria
Use of Rapid Diagnostic Tests for Malaria Case Management in Kenya
The purpose of this study is to investigate the impact of rapid diagnostic tests (RDTs) in the context of a newly implemented malaria case management guidelines using artemisinin-based combination therapy on the malaria…
- Trial name
- NCT00336388
- Testing
- Paracheck Device
- Where
- Kenya
- Volunteers
- 3,600 people
- Sponsor
- Centers for Disease Control and Prevention
Diarrhea
Impact of Home Zinc Treatment for Acute Diarrhea in Children
Background. Zinc deficiency is common in Africa. It has been shown in Asia that zinc as treatment for diarrhea can shorten the course of episodes of diarrhea, as well as prevent future episodes.
- Trial name
- NCT00530829
- Testing
- zinc
- Where
- Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
AIDS, Antiretroviral Therapy
The Impact of Short Message Services (SMS) on ARV Adherence in Western Kenya
The purpose of proposed research is to implement a randomized study that will allow us to understand and address a number of key barriers to patient adherence as well as study the effects of better adherence on health and…
- Conditions
- AIDS, Antiretroviral Therapy, Medication Adherence, HIV Infections
- Trial name
- CAPS (NCT01058694)
- Testing
- Short Message Services to Support ARV therapy adherence
- Where
- Kenya
- Volunteers
- 720 people
- Sponsor
- Georgetown University
Schistosoma Mansoni
A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni
The purpose of this study is to determine the comparative efficacy of artesunate plus sulfamethoxypyrazine-pyrimethamine versus Praziquantel in the treatment of school children infected with S.mansoni in western Kenya.
- Trial name
- NCT01054651
- Testing
- Artesunate+Sulfamethoxypyrazine/pyrimethamine, Praziquantel
- Where
- Kenya
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Kenya Medical Research Institute
Anaemia, Schistosomiasis Infection
Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment
The purpose of this study is to determine the extend and the nature of anemia in school children and the correlation between anemia and schistosomiasis infections, malaria infections and/or malnutrition (iron deficiency).
- Conditions
- Anaemia, Schistosomiasis Infection, Malaria, Iron Deficiency
- Trial name
- NCT00414479
- Testing
- praziquantl, iron, ACT
- Where
- Kenya
- Volunteers
- 1,500 people
- Sponsor
- DBL -Institute for Health Research and Development
Malaria
A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria
The primary objective is to assess the safety of different doses of ferroquine with artesunate (AS) in adult African patients with uncomplicated malaria.
- Trial name
- NCT00563914
- Testing
- ferroquine (SSR97193), amodiaquine
- Where
- 2 sites in Gabon, Kenya
- Volunteers
- 72 people
- Sponsor
- Sanofi
Sexually Transmitted Infections
62% & 15% Ethanol in Emollient Gel as Topical Male Microbicides
The purpose of this study is to look at the safety and acceptance of using a microbicide (product that kills germs) gel to clean the genital area. Microbicide gel is used by hospital workers to clean their hands to kill germs.
- Trial name
- NCT00469547
- Testing
- 62% ethanol in emollient gel, 15% ethanol in emollient gel
- Where
- Kenya
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV, Malnutrition
Study of Impacts of Food Supplementation on Malnourished HIV-Infected Adults in Kenya
The purpose of the study is to test whether food supplementation of malnourished HIV-infected adults (both pre-ART and ART) in resource constrained settings improves their nutritional status, clinical status, effectiveness of…
- Conditions
- HIV, Malnutrition, HIV Infections
- Trial name
- NCT00838292
- Testing
- fortified blended flour - Insta Foundation Plus (with whey protein concentrate), nutrition counseling
- Where
- 6 sites in Kenya
- Volunteers
- 1,049 people
- Sponsor
- Academy for Educational Development
Malaria, Falciparum
Efficacy and Safety of the Pediatric Formulation of Artemether- Lumefantrine in Children With Uncomplicated P. Falciparum Malaria.
This study will evaluate the safety and efficacy of artemether-lumefantrine against uncomplicated malaria caused P. falciparum in children of 5-35 kg bodyweight.
- Trial name
- NCT00386763
- Testing
- Artemether-lumefantrine
- Where
- 5 sites in Benin, Kenya and 3 more
- Volunteers
- 890 people
- Sponsor
- Novartis
Falciparum Malaria, Uncomplicated Malaria
Phase II Dose Ranging Study of Artesunate
The purpose of this study is to compare four regimens using US FDA GMP intravenous artesunate for the treatment of uncomplicated Plasmodium falciparum malaria to identify the most effective treatment regimen as determined by…
- Trial name
- NCT00459615
- Testing
- Artesunate for Injection
- Where
- 2 sites in Kenya, Thailand
- Volunteers
- 120 people
- Sponsor
- U.S. Army Office of the Surgeon General
Malaria
Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.
To compare Azithromycin plus Chloroquine versus Mefloquine to treat uncomplicated plasmodium falciparum malaria.
- Trial name
- NCT00367653
- Testing
- Azithromycin plus Chloroquine, Mefloquine
- Where
- 8 sites in Burkina Faso, Ghana and 4 more
- Volunteers
- 397 people
- Sponsor
- Pfizer
Cataract, Endophthalmitis
The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision).
- Trial name
- NCT00730938
- Testing
- cefuroxime
- Where
- Kenya
- Volunteers
- 45 people
- Sponsor
- Presbyterian Church East Africa Kikuyu Hospital
Consumer Willingness to Pay for POU Products, Consumer Preferences and Use of POU Products
Safe Water Techniques in Kenya
Consumer preferences for POU technologies vary across consumers and products, and largely determine their adoption and subsequent usage.
- Trial name
- NCT00531869
- Testing
- biases towards products
- Where
- Kenya
- Sponsor
- University of California, Berkeley
Plasmodium Falciparum Malaria
Evaluation of Safety and Efficacy of Artemether-Lumefantrine Tablets in African Infants and Children With Uncomplicated P. Falciparum Malaria
This study will assess the safety and efficacy of artemether-lumefantrine tablets (6-dose regimen) in African infants / children with acute uncomplicated falciparum malaria.
- Trial name
- NCT00709969
- Testing
- Artemether-lumefantrine
- Where
- 3 sites in Kenya, Nigeria and 1 more
- Volunteers
- 310 people
- Sponsor
- Novartis
HIV Infections
Male Circumcision and HIV Rates in Kenya
The Luo tribe of Kisumu, Kenya, does not traditionally practice male circumcision (MC). This study will work with the Luo tribe to test the effectiveness of MC on reducing the risk of HIV infections in young men.
- Trial name
- NCT00059371
- Testing
- male circumcision
- Where
- Kenya
- Volunteers
- 2,887 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Malaria, Falciparum
Randomised Efficacy Study of Two Artemether-Lumefantrine Oral Formulations for the Treatment of Uncomplicated P. Falciparum Malaria
The purpose of this study is to compare the safety and efficacy in children aged 6 - 59 months with uncomplicated malaria, treated with either conventional artemether/lumefantrine tablets(Coartem®) or artemether/ lumefantrine…
- Trial name
- NCT00529867
- Testing
- Artemether/lumefantrine tablets, Artemether/Lumefantrine suspension
- Where
- Kenya
- Volunteers
- 267 people
- Sponsor
- Dafra Pharma
HIV, Acquired Immunodeficiency Syndrome
The Efficacy of the HIV/AIDS Symptom Management Manual
The goals of this research are: 1) To test the efficacy of a self-care symptom management manual by examining whether people who use the manual find it to be useful; 2) To examine symptom and demographic data related to self-care…
- Trial name
- NCT00241202
- Testing
- Symptom Management Manual
- Where
- 11 sites in United States, Kenya and 2 more
- Volunteers
- 775 people
- Sponsor
- University of California, San Francisco
HIV Infections, Helminthiasis
Treatment of Helminth co-Infection: Short-Term Effects on HIV-1 Progression Markers and Immune Activation
Identifying methods to slow disease progression in patients with HIV-1 infection remains a top priority in many regions of the world.
- Trial name
- NCT00130910
- Testing
- Albendazole
- Where
- Kenya
- Volunteers
- 234 people
- Sponsor
- University of Washington
Schistosomiasis Mansoni, Circulating Cathodic Antigen Urine Based Dipstick
Evaluation of the Use of a Urin Test Strip to Determine the Spread of Schistosoma Infections in Areas Where Schistosomiasis Infections Are Low in Kenya
The purpose of this study is to evaluate the use of a urine test strip in diagnose schistosoma mansoni in areas of Kenya where the rate of infections are low.
- Trial name
- NCT00463307
- Where
- Kenya
- Volunteers
- 1,100 people
- Sponsor
- DBL -Institute for Health Research and Development