Clinical trials: in Kenya
HIV, Malaria
Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate Resistance
At least three studies in sub-Saharan Africa have demonstrated a decrease in morbidity or mortality among HIV-infected adults who took daily cotrimoxazole (trimethoprim sulfamethoxazole) [CTX] prophylaxis.
- Conditions
- HIV, Malaria, Diarrhea, Pneumonia
- Trial name
- NCT00137657
- Testing
- Cotrimoxazole (trimethoprim sulfamethoxazole)
- Where
- Kenya
- Volunteers
- 1,478 people
- Sponsor
- Centers for Disease Control and Prevention
Tuberculosis
A Controlled Trial of a 4-Month Quinolone-Containing Regimen for the Treatment of Pulmonary Tuberculosis
Tuberculosis is currently treated with a 6-month course regimen. During this time many patients might fail to adhere to treatment and default, increasing the risk of recurrent disease which might be multidrug resistant.
- Trial name
- NCT00216385
- Testing
- Gatifloxacin combined regimen
- Where
- 5 sites in Benin, Guinea and 3 more
- Volunteers
- 2,070 people
- Sponsor
- Institut de Recherche pour le Developpement
Malaria, HIV
In-Vivo Response of P. Falciparum to Antimalarial Treatment in HIV-Infected and HIV-Uninfected Adults
Plasmodium falciparum malaria and HIV are among the most important infectious diseases in sub-Saharan Africa. Approximately two-thirds of the estimated 35 million HIV infected persons live in sub-Saharan Africa.
- Conditions
- Malaria, HIV, AIDS
- Trial name
- NCT00144352
- Testing
- sulfadoxine-pyrimethamine
- Where
- Kenya
- Volunteers
- 540 people
- Sponsor
- Centers for Disease Control and Prevention