Clinical trials: completed, in Lithuania
Stress, Psychological
Internet-Based Stress Recovery Program for Adolescents
The study aims to evaluate the feasibility and efficacy of the internet-based stress recovery program for adolescents.
- Trial name
- FOREST-A (NCT05688254)
- Testing
- FOREST-A
- Where
- Lithuania
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Influenza, Human
A Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an Adjuvanted Influenza Vaccine Compared to a Non-adjuvanted Influenza Vaccine in Adults ≥65 Years of Age
This Phase 3 study is a randomized, observer-blind study of MF59-adjuvanted influenza vaccine (aQIV or aTIV) compared with a non-adjuvanted influenza vaccine (QIV or TIV) in adults ≥65 years of age.
- Trial name
- NCT06087640
- Testing
- aQIV or aTIV, QIV or TIV
- Where
- 255 sites in United States, Australia and 19 more
- Volunteers
- 38,769 people, healthy volunteers welcome
- Sponsor
- Seqirus
Healthy Adult, Cyclists
Musculotendinous Adaptations to Strength and Endurance Training in Cyclists
This study investigated whether adding strength training to regular endurance training improves performance and muscle function in competitive cyclists.
- Conditions
- Healthy Adult, Cyclists, Athletes
- Trial name
- STEND (NCT07658300)
- Testing
- Strength training, Endurance training
- Where
- Lithuania
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Military Personnel, Low Back Pain
Low Back Pain and Hamstring-to-Quadriceps Strength Ratio in Military Personnel
The aim of this study was to determine the association between low back pain and the strength of knee flexor and extensor muscles in Lithuanian National Defence Volunteer Forces personnel.
- Trial name
- LBP-H/Q ratio (NCT07606040)
- Where
- Lithuania
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Physical Activity, eHealth Literacy
Digital Literacy Training and Acceptance of Physical Activity Apps in Older Women
This randomized controlled study examined whether a structured digital literacy training program could improve eHealth literacy, acceptance of physical activity applications, and behavioral intentions among older women.
- Conditions
- Physical Activity, eHealth Literacy, Technology Acceptance
- Trial name
- NCT07515898
- Testing
- Digital Literacy Training Program
- Where
- Lithuania
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healthy Adult Participants
The Effect of Cold Exposure on Physiological Markers
The goal of this observational study is to examine how different physiological markers change over a two-day period after long-duration whole-body cold-water immersion in healthy young men and women.
- Trial name
- NCT07504718
- Testing
- Cold water immerssion
- Where
- Lithuania
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healthy Adult Male
Short-Term Broccoli Supplementation and Acute Oxidative Stress Recovery
The study aimed to evaluate the effects of short-term broccoli powder supplementation on metabolically demanding exercise performance, muscle power, and blood lactate recovery.
- Trial name
- NCT07454265
- Testing
- Broccoli powder
- Where
- Lithuania
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healthy Subjects
Effect of Squats on Postural Stability, Bilateral Coordination and Dynamic Balance
The aim of this interventional study was to evaluate the immediate effects of a single bout of 30 squats performed on an unstable surface versus a stable surface on postural stability, bilateral coordination, and dynamic balance…
- Trial name
- NCT07341555
- Testing
- Condition - no exercise before testing, Condition - exercise on unstable surface, Condition - exercise on stable surface
- Where
- Lithuania
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healthy Participants
The Effect of Daily Brief Heat Exposures on Heat Acclimation
This study is the first to examine the effects of short passive heat exposure on heat acclimation (HA). Unlike traditional protocols requiring prolonged heat exposure, this study tests whether a daily 5-minute whole-body…
- Trial name
- NCT07198334
- Testing
- Heat acclimation
- Where
- Lithuania
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healthy, Psychological Distress
The Effects of the Somatic Intervention 'Dance-Walk' on Body Awareness, Vitality, and Mental Health in Help-Seeking Adults: a RCT Study
The goal of this clinical trial is to learn if a movement program called "Dance-Walk" can improve body awareness, energy levels, and mental health in adults seeking mental health support.
- Conditions
- Healthy, Psychological Distress, Stress, Depression Disorders
- Trial name
- DANCEWALK (NCT07024901)
- Testing
- Dance-walk
- Where
- Lithuania
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Tinnitus, Distress, Emotional
Internet-delivered Psychological Interventions for Tinnitus
Tinnitus can be very distressing for some individuals who experience it. The most studied intervention that works well for tinnitus distress is cognitive behavioral therapy (CBT).
- Conditions
- Tinnitus, Distress, Emotional, Depression, Anxiety, Sleep
- Trial name
- TinnitusLT (NCT05705323)
- Testing
- Internet-delivered cognitive behavioral therapy (iCBT), Internet-delivered mindfulness-based tinnitus stress reduction (iMBTSR)
- Where
- Lithuania
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Healthy Subjects
Comparative Effects of Vocal and Breathing Exercises on Respiratory Function and Trunk Stability in Women
The goal of this randomized clinical trial is to investigate whether vocal exercises or breathing exercises improve respiratory function and trunk stability in healthy adult women aged 18-65.
- Trial name
- VO vs BE (NCT07175844)
- Testing
- Vocal exercises, Breathing exercises
- Where
- 2 sites in Lithuania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healthy Adult Male
The Effect of Heat Exposure on Physiological Markers
This study is the first to examine the effects of core temperature elevation on kynurenine pathway (KP) metabolites in healthy young males.
- Trial name
- NCT07064512
- Testing
- Endogenous heating, Exogenous heating
- Where
- Lithuania
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healthy Male and Female Subjects
A Comparative Bioavailability Study of Reformulated Ibuprofen 2% and 4% Oral Suspensions (Berlin Chemie AG) and Versus Ibuprofen (Nurofen®) 200 mg/5 ml Oral Suspension
Purpose of the study is to compare three different formulations of Ibuprofen oral suspension (liquid taken by mouth) to see if there are any differences in how much of the active substance and how quickly it was taken up by by…
- Trial name
- NCT07036861
- Testing
- Ibuprofen 2%, Ibuprofen 4%
- Where
- 2 sites in Lithuania
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Berlin-Chemie AG Menarini Group
Prevention of COVID-19
Assessing Immune Response of Different COVID-19 Vaccines in Older Adults
This is a randomised controlled, adaptive, multicentre Phase II protocol evaluating different booster strategies in individuals aged 75 years and older already vaccinated against SARS-CoV-2.
- Trial name
- EU-COVAT-1 (NCT05160766)
- Testing
- Comirnaty (BTN162b2), Spikevax (mRNA-1273)
- Where
- 9 sites in Germany, Lithuania and 2 more
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Oliver Cornely, MD
Cervical Intraepithelial Neoplasia
A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age
The main purpose of this study was to evaluate the safety and reactogenicity of GlaxoSmithKline Biologicals SA (GSK)'s investigational adjuvanted human papillomavirus (HPV) vaccine formulations.
- Trial name
- NCT05496231
- Testing
- HPV9 High formulation, HPV9 Medium formulation, HPV9 Low formulation
- Where
- 68 sites in United States, Bulgaria and 6 more
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Vasomotor Symptoms, Menopausal Symptoms
Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)
This is a two-part study designed to evaluate the effect of Estetrol (E4) 15 or 20 mg, or placebo on the severity and frequency of vasomotor symptoms (VMS) (Efficacy Study Part) and the safety of E4 20 mg (Endometrial and General…
- Trial name
- NCT04209543
- Testing
- Estetrol, Progesterone
- Where
- 224 sites in United States, Argentina and 12 more
- Volunteers
- 1,570 people, healthy volunteers welcome
- Sponsor
- Estetra
Dermatological Non-Disease
Efficacy and Safety of the BeShape One Device for Non-invasive Waist Circumference Reduction
The goal of this clinical trial is to evaluate the safety and efficacy of the BeShape One device for non-invasive waist circumference reduction in adults between the ages of 18 and 65.
- Trial name
- NCT05896696
- Testing
- BeShape One
- Where
- 2 sites in United States, Lithuania
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- BeShape Technologies Ltd.
Aging, Cognitive Decline
Blood Flow Restriction and High-intense Resistance Training in Aging: Interactions Between Neuroplasticity and Muscle
BRAIN-M is a randomized controlled trial designed to examine the effects of a single bout or 12 weeks of blood-flow restriction training or high-intensity resistance training on cognitive function, brain health, muscular…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Frailty
- Trial name
- BRAIN-M (NCT05744167)
- Testing
- BFRT, MDRT
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Drug Adherence
Patient Autonomy and Statin Therapy Adherence
The rationale for the Patient Autonomy and Statin Therapy Adherence (PASTA) trial is based on the fact that statin therapy is a highly effective and evidence-based treatment for reducing the risk of cardiovascular disease.
- Trial name
- PASTA (NCT05845580)
- Testing
- Red yeast rice extract initial therapy followed later on by statin therapy, Statin therapy
- Where
- Lithuania
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences