Clinical trials: in Mauritius
Metabolic Syndrome
Effect of Moringa Oleifera Infusion on Health
The study aims at investigating the effects of the consumption of Moringa oleifera Lam leaves on biomedical markers of health among healthy individuals who are hyperglycaemic with a fasting blood glucose equal or greater than…
- Trial name
- MOI (NCT04314258)
- Testing
- Moringa oleifera tea
- Where
- Mauritius
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Mauritius
Sunburn
Clinical Trial of the Safety and Efficacy of SP160412 in the Temporary Relief of Mild to Moderate Sunburn
A phase II multicenter, double-blinded clinical trial of the safety and efficacy of SP160412 in the temporary relief of mild to moderate, (i.e. first degree) sunburn
- Trial name
- NCT03332524
- Testing
- SP160412 Ibuprofen 400 mg and Chlorpheniramine maleate 4 mg
- Where
- Mauritius
- Volunteers
- 80 people
- Sponsor
- Sephoris Pharmaceuticals LLC
Chronic Hepatitis C
A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of the Combination of AL-335, Odalasvir, and Simeprevir
The purpose of this study is to evaluate the safety and tolerability of AL-335 in combination with odalasvir (ODV) with or without simeprevir (SMV) in participants with genotype (GT)1 or GT2 or GT3 chronic hepatitis C (CHC)…
- Trial name
- NCT02569710
- Testing
- AL-335, Odalasvir (ODV), Simeprevir (SMV)
- Where
- 11 sites in Mauritius, Moldova and 2 more
- Volunteers
- 161 people
- Sponsor
- Alios Biopharma Inc.
Lupus Erythematosus, Systemic
Study of Repeated Administration of a 200-mcg Dose of IPP-201101 Plus Standard of Care in Patients With Systemic Lupus Erythematosus
this study extension objective is to evaluate the safety and tolerability of a 200-mcg dose every 4 weeks for 24 weeks of IPP-201101 in patients with active systemic lupus erythematosus (SLE) who had participated in the main…
- Trial name
- IP-006 (NCT03427151)
- Testing
- IPP-201101
- Where
- 14 sites in United States, Czechia and 5 more
- Volunteers
- 62 people
- Sponsor
- ImmuPharma
Lupus Erythematosus, Systemic
A 52-Week, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a 200-mcg Dose of IPP-201101 Plus Standard of Care in Patients With Systemic Lupus Erythematosus
This current Phase 3 study will evaluate the efficacy and safety of administration of subcutaneous (sc) IPP-201101 in patients with active SLE.
- Trial name
- LUPUZOR (NCT02504645)
- Testing
- IPP-201101, Standard of Care
- Where
- 30 sites in United States, Czechia and 6 more
- Volunteers
- 202 people
- Sponsor
- ImmuPharma
Systemic Lupus Erythematosus
ILT-101 in Patients With Active Moderate to Severe Systemic Lupus Erythematosus (SLE)
The purpose of this study is to evaluate the efficacy and safety of ILT-101 (human recombinant interleukin 2 (IL-2)) in patients with moderate to severe systemic lupus erythematosus.
- Trial name
- LUPIL-2 (NCT02955615)
- Testing
- ILT-101
- Where
- 25 sites in Austria, Bulgaria and 8 more
- Volunteers
- 100 people
- Sponsor
- Iltoo Pharma
ST-segment Elevation Myocardial Infarction (STEMI)
Effect of Remote Ischemic Conditioning in Heart Attack Patients
New treatments are required to improve health outcomes in patients with ischemic heart disease. This is especially so in developing countries such as Mauritius in which optimal therapy for acute myocardial infarction may not be…
- Trial name
- ERIC-LYSIS (NCT02197117)
- Testing
- Remote ischemic conditioning, Control
- Where
- 5 sites in Mauritius
- Volunteers
- 519 people
- Sponsor
- University College, London
Surgery, Surgery- Complications
African Surgical Outcomes Study (ASOS)
STUDY OBJECTIVE To confirm the incidence of in-hospital postoperative complications in adult surgical patients in Africa. STUDY DESIGN Seven day, African national multi-centre prospective observational cohort study of adult (≥18…
- Conditions
- Surgery, Surgery- Complications, Mortality
- Trial name
- ASOS (NCT03044899)
- Testing
- All surgeries in adult patients
- Where
- 25 sites in Algeria, Benin and 23 more
- Volunteers
- 11,422 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Human Immunodeficiency Virus Infections
Safety, PK and PD Study of ABX464 in Untreated HIV Patients
ABX464 is a first in class that showed efficacy as an anti-HIV therapy. The present study is intended to assess the safety, the tolerability, and pharmacokinetic parameters and to evaluate the effect on viral load of repeated…
- Trial name
- NCT02452242
- Testing
- ABX464
- Where
- 4 sites in Mauritius, Thailand
- Volunteers
- 70 people
- Sponsor
- Abivax S.A.
Healthy Volunteers
Food Effect on Pharmacokinetic Parameters of ABX464
The goal of this study is to determine the impact of the food on the absorption of the ABX464.
- Trial name
- NCT02731885
- Testing
- ABX464 Single dose, ABX464 Repeated dose
- Where
- Mauritius
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Abivax S.A.
Diabetic Nephropathy, Diabetic Kidney Disease
Pyridorin in Diabetic Nephropathy
The purpose of this study is to evaluate the safety and efficacy of oral Pyridorin 300 mg BID in reducing the rate of progression of nephropathy due to type 2 diabetes mellitus.
- Trial name
- PIONEER (NCT02156843)
- Testing
- Pyridorin
- Where
- 137 sites in United States, Australia and 10 more
- Volunteers
- 328 people
- Sponsor
- NephroGenex, Inc.
Hepatitis C, Chronic
A Phase 1a/1b Study of PPI-383 in Healthy Adults and Hepatitis C Patients
PPI-383 is an antiviral agent (an inhibitor of the hepatitis C virus NS5B polymerase) that is being developed as a potential treatment for hepatitis C virus infection.
- Trial name
- NCT01928147
- Testing
- PPI-383
- Where
- 6 sites in Mauritius, United Kingdom
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Presidio Pharmaceuticals, Inc.
Assess the Effect of Green Tea on Diabetes, Assess the Effect of Fermented Papaya Pretration on Diabetes
Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases
Type 2 diabetes is common in ethnic and, minority groups in developing and developed countries such as Africans, African Americans, Asians, Native Americans, Hispano-Latinos and Alaskan indians.
- Conditions
- Assess the Effect of Green Tea on Diabetes, Assess the Effect of Fermented Papaya Pretration on Diabetes, Effects of Green Tea and FPP on C-reactive Proteins, Effects of Green Tea and FPP of Lipid Profiles in Diabetes
- Trial name
- NCT01248143
- Testing
- Green tea, FPP
- Where
- 3 sites in United States, Austria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Antisocial, Aggressive
Effect of Omega-3 Supplementation on Child Behavior Problems
The primary purpose of this study was to assess the effectiveness of omega-3 supplementation on behavior problems in children.
- Conditions
- Antisocial, Aggressive, Externalizing Behavior Problems, Internalizing Behavior Problems
- Trial name
- NCT02016079
- Testing
- omega-3
- Where
- Mauritius
- Volunteers
- 200 people
- Sponsor
- Joint Child Health Project, Mauritius
Cardiac Disease
Effects of Black Tea on Cardiovascular Disease in the Mauritian Population
It is proposed to investigate the association between consumption of black tea and various selective fasting blood serum and urine biomarkers in a Mauritian population with ischaemic heart diseases.
- Trial name
- NCT00114907
- Testing
- Consumption of black tea
- Where
- Mauritius
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Mauritius
Dyssocial Behavior, Antisocial Personality Disorder
Antisocial Behavior: Passing From Parent to Child to Grandchild
Antisocial behavior often occurs in different generations within the same family. However, it is not known what factors contribute to this passing of antisocial behavior from parent to child to grandchild.
- Trial name
- NCT00060788
- Where
- Mauritius
- Volunteers
- 663 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)