Clinical trials: completed, in Oman
Ventilator Associated Pneumonia, Multi-antibiotic Resistance
Ventilator Associated Pneumonia by Multi-Drug Resistant Organism
Ventilator-associated pneumonia (VAP) is an infection of the pulmonary parenchyma in patients exposed to invasive mechanical ventilation for at least 48 h and is part of ICU-acquired pneumonia.
- Trial name
- VAP-MDR (NCT05549427)
- Testing
- Ventilation
- Where
- Oman
- Volunteers
- 319 people
- Sponsor
- Sultan Qaboos University
Rupture of Anterior Cruciate Ligament
Arthroscopic Primary Repair of the Anterior Cruciate Ligament (ACL)
A prospective cohort study that will be conducted at Sultan Qaboos University Hospital. It aims to determine the outcomes, in terms of, activity level, functional level, subjective knee function, range of motion, stability, and…
- Trial name
- NCT03510845
- Testing
- Arthroscopic ACL Primary Repair, Arthroscopic ACL Reconstruction
- Where
- Oman
- Volunteers
- 45 people
- Sponsor
- Sultan Qaboos University
Acute Kidney Injury, COVID-19
Incidence of Acute Kidney Injury in Covid-19
Acute kidney injury (AKI) in Covid-19 patients is a topic that receives little attention in the literature, although being important in clinical practice in the ICU, particularly in Oman.
- Conditions
- Acute Kidney Injury, COVID-19, Critically Ill
- Trial name
- COVIDAKI (NCT05467956)
- Testing
- Covid-19
- Where
- Oman
- Volunteers
- 286 people
- Sponsor
- Sultan Qaboos University
Non-Covid, COVID-19
Comparison Between Early and Late Tracheostomy in Non-Covid and Covid
Tracheostomy is commonly indicated for the patient who is requiring long period of mechanical ventilation. Patient who require mechanical ventilation for >10 days and longer mostly get tracheostomized.
- Trial name
- CELT (NCT05465837)
- Testing
- Tracheostomy
- Where
- Oman
- Volunteers
- 156 people
- Sponsor
- Sultan Qaboos University
Acute Pharyngitis
Inhaled Steroids for Acute Pharyngitis.
Background: Acute pharyngitis (AP) is a common presentation to the Emergency Department (ED). Most AP patients' who present to the ED are interested in relief their sore throat (pain).
- Trial name
- ISAP (NCT04027322)
- Testing
- Budesonide 0.25 MG/ML Inhalant Solution, Dexamethasone, Normal saline
- Where
- 3 sites in Oman
- Volunteers
- 200 people
- Sponsor
- Oman Medical Speciality Board
Type 2 Diabetes Mellitus
DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings
DISCOVER is a Non Interventional Study study to describe the disease management patterns and clinical evolution over three years in type 2 diabetes mellitus patients initiating a second line anti-diabetic treatment.
- Trial name
- DISCOVER (NCT02322762)
- Where
- 303 sites in Algeria, Argentina and 30 more
- Volunteers
- 15,992 people
- Sponsor
- AstraZeneca
Acute Renal Colic
Atomized Intranasal Vs Intravenous Ketorolac in Acute Renal Colic Pain Management.
Introduction: Pain is a common reason for individuals to seek health care, especially emergency care. Ketorolac has numerous advantages over other pain medications, especially the opioids.
- Trial name
- Ink-Arc (NCT04441762)
- Testing
- Intravenous Ketorolac Tromethamine, Intranasal Ketorolac Tromethamine
- Where
- Oman
- Volunteers
- 171 people
- Sponsor
- Oman Medical Speciality Board
Idiopathic Pulmonary Fibrosis
A Clinical Study to Test How Effective and Safe GLPG1205 is for Participants With Idiopathic Pulmonary Fibrosis (IPF)
This is a randomized, double-blind, parallel-group, placebo-controlled, multicenter, exploratory Phase 2 study including participants with Idiopathic Pulmonary Fibrosis (IPF), investigating GLPG1205 in addition to the local…
- Trial name
- PINTA (NCT03725852)
- Testing
- GLPG1205
- Where
- 36 sites in Bulgaria, Croatia and 7 more
- Volunteers
- 68 people
- Sponsor
- Lakefront Biotherapeutics NV
Obstetric Anaesthesia With Cardiac Complications
A Superior Anesthetic Technique for the Cesarean Section From a Hemodynamic Perspective.
Cesarean section operations are increasing in rates worldwide. A proper anesthetic technique is required to maintain the safety of both the mother and the fetus.
- Trial name
- NCT04989270
- Testing
- General Anesthesia, Regional Anesthesia
- Where
- Oman
- Volunteers
- 2,500 people
- Sponsor
- Sultan Qaboos University
Non-small Cell Lung Cancer
A Study Comparing MB02 and Avastin® in Subjects With Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
This is a multicenter, multinational, double-blind, 1:1 randomized, parallel-group, equivalence Phase 3 study to compare the efficacy and safety of MB02 plus chemotherapy (carboplatin and paclitaxel) versus Avastin® plus…
- Trial name
- STELLA (NCT03296163)
- Testing
- MB02 (Bevacizumab Biosimilar Drug), EU-approved Avastin®, Carboplatin
- Where
- 118 sites in Brazil, Bulgaria and 16 more
- Volunteers
- 627 people
- Sponsor
- mAbxience Research S.L.
Postoperative Complications, Comorbidities and Coexisting Conditions
Study of Direct Admission of Postoperative Patients to ICU
Background: This study assessed perioperative factors associated with planned and unplanned postoperative ICU admission and evaluated the outcome of the two groups. There are limited researches evaluating these factors.
- Trial name
- NCT04680208
- Testing
- Surgical procedure under anesthesia
- Where
- Oman
- Volunteers
- 68 people
- Sponsor
- Sultan Qaboos University
Severe Asthma
Assessment of Treatment Patterns of Severe Asthmatic Patients Across the Gulf Region - SevEos Study
SevEos is a cross-sectional, multi-center, non-interventional study aimed to describe the treatment patterns in 250 severe asthma patients across the Gulf region.
- Trial name
- SevEos (NCT03387722)
- Where
- 2 sites in Oman, United Arab Emirates
- Volunteers
- 253 people
- Sponsor
- AstraZeneca
Iron Overload
Safety Study of Crushed Deferasirox Film Coated Tablets in Pediatric Patients With Transfusional Hemosiderosis
This study employed a prospective, single-arm, global multi-center interventional open-label, non-randomized design to identify and assess safety profile of the crushed deferasirox FCT when administered up to 24 weeks in…
- Trial name
- MIMAS (NCT03372083)
- Testing
- Deferasirox
- Where
- 10 sites in Egypt, Italy and 5 more
- Volunteers
- 44 people
- Sponsor
- Novartis Pharmaceuticals
Traumatic Brain Injury, Education
VAGABOND: a Mnemonic to Aid in the Memory Retention of the Canadian CT Head Rule
The aim of this study is to assess the effectiveness and usefulness of a simple one word mnemonic in the memory retention of the different components of the Canadian CT Head Rule (CCHR) in senior medical students and interns.
- Trial name
- NCT03565549
- Testing
- Mnemonic, CCHR rule
- Where
- Oman
- Volunteers
- 100 people
- Sponsor
- Sultan Qaboos University
Prostate Cancer, Castration-resistant Prostate Cancer
A Study to Describe Patterns of Care and Outcomes of Men Who Are at High Risk After Experiencing Biochemical Failure Following Definitive Prostate Cancer Therapy, Men With Castration-resistant Prostate Cancer and Men With Metastatic Prostate Cancer
The purpose of this study is to describe patterns in disease management and to describe clinical outcomes, as well as to identify factors influencing physician treatment decisions including reason(s) for treatment choices and…
- Conditions
- Prostate Cancer, Castration-resistant Prostate Cancer, Metastatic Prostate Cancer
- Trial name
- ASPIRE-PCa (NCT02066961)
- Where
- 93 sites in Algeria, Argentina and 25 more
- Volunteers
- 1,533 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Sickle-Cell Disease
Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD
A Multi-Centre, Phase II, Randomized, Double-Blind, Placebo-Controlled Study to investigate Efficacy and Safety of Sevuparin Infusion for the Management of Acute Vaso-Occlusive Crisis (VOC) in Subjects with Sickle-Cell Disease…
- Trial name
- NCT02515838
- Testing
- Sevuparin
- Where
- 20 sites in Bahrain, Jamaica and 5 more
- Volunteers
- 147 people
- Sponsor
- Modus Therapeutics AB
Delirium, Anesthesia; Adverse Effect
Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors
Delirium is considered to be acute failure of central nervous system. It is acute confusional state characterized by decline from baseline mental level, attention deficit and disorganized thinking.
- Trial name
- AIPDAP (NCT03967496)
- Testing
- Types of Anesthesia, Access of Surgery, Comorbidities
- Where
- Oman
- Volunteers
- 402 people
- Sponsor
- Sultan Qaboos University
Coronary Artery Disease, Radial Artery Injury
Comparison of Two Protocols for Deflation of Radial Band Following Coronary Procedures Via the Radial Artery
Coronary angiography is now mainly performed via the radial route rather than the femoral route. At the end of the procedure, the sheath is removed and a band is inflated to obtain hemostasis.
- Trial name
- SQUARE1 (NCT03380065)
- Testing
- Late deflation of TR band, Early deflation of TR band
- Where
- Oman
- Volunteers
- 200 people
- Sponsor
- Sultan Qaboos University
Hemophilia A
Study Evaluating Prophylaxis Treatment & Characterizing Efficacy, Safety, & PK Of B-Domain Deleted Recombinant FVIII
The purpose of this research study is to determine the effectiveness, safety, and pharmacokinetics (PK) of moroctocog alfa (AF-CC) in previously treated subjects, who are younger than 6 years of age, with severe or moderately…
- Trial name
- NCT00543439
- Testing
- Moroctocog alfa (AF-CC)
- Where
- 28 sites in United States, Argentina and 11 more
- Volunteers
- 66 people
- Sponsor
- Pfizer
Non-Squamous Non-Small Cell Lung Cancer
A Study of Bevacizumab in Combination With Standard of Care Treatment in Participants With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC)
This open-label, randomized, multicenter study will evaluate the efficacy and safety of bevacizumab (Avastin) in combination with standard of care (SOC) treatment in participants with advanced non-squamous NSCLC.
- Trial name
- NCT01351415
- Testing
- Bevacizumab, Docetaxel, Erlotinib
- Where
- 179 sites in United States, Argentina and 16 more
- Volunteers
- 485 people
- Sponsor
- Hoffmann-La Roche