Clinical trials: in Philippines
Ametropia
Safety and Efficacy of Different Add Powers With a New Presbyopic Lasik Treatment Algorithm
This is a prospective, comparative, randomized, controlled, open-label, single-surgeon, single-center PMCF clinical study whereby presbyopic patients undergoing refractive surgery will receive a SUPRACOR treatment for the…
- Trial name
- NCT04617080
- Testing
- SUPRACOR Regular, SUPRACOR Strong
- Where
- Philippines
- Volunteers
- 60 people
- Sponsor
- Bausch & Lomb Incorporated
Herpes Zoster
The Safety and Immunogenicity Study of the Recombinant Zoster Vaccine (CHO Cell)
This is a randomized, observer-blinded, active-controlled Phase I study to evaluate the safety, reactogenicity, and immunogenicity of REC610, when administered as 2 intramuscular (IM) injections in healthy adults aged 40 years…
- Trial name
- NCT05769049
- Testing
- REC610, Shingrix
- Where
- Philippines
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Jiangsu Rec-Biotechnology Co., Ltd.
COVID-19
Safety, and Immunogenicity Study of the Recombinant Two-component COVID-19 Vaccine (CHO Cell)
Part 1: Primary Vaccination in Adults Part 1 will evaluate the safety and immunogenicity of the recombinant two component COVID-19 vaccine (CHO cell) (ReCOV for short) in adults aged 18 years and older, when administered as 2…
- Trial name
- ReCOV (NCT05084989)
- Testing
- Part1:Recombinant two-component COVID-19 vaccine (CHO cell), Part2: Recombinant two-component COVID-19 vaccine (CHO cell), Part2: COVID-19 Vaccine, mRNA
- Where
- Philippines
- Volunteers
- 948 people, healthy volunteers welcome
- Sponsor
- Jiangsu Rec-Biotechnology Co., Ltd.
Atopic Dermatitis
Cetaphil Restoraderm Effect on Young Children With Atopic Dermatitis
The purpose of this study is to evaluate the effect of Cetaphil® Restoraderm® skin restoring moisturizer in reducing the signs and symptoms of very dry atopic skin in young children.
- Trial name
- NCT02589392
- Testing
- Cetaphil® Restoraderm® moisturizer + Cetaphil® Restoraderm® body wash, Cetaphil® Restoraderm® body wash
- Where
- 8 sites in China, Philippines
- Volunteers
- 120 people
- Sponsor
- Galderma R&D
Locally Advanced Cervical Carcinoma
Decision Aid for Chemotherapy in Cisplatin-Intolerant Patients With Locally Advanced Cervical Cancer
The goal of this clinical trial is to investigate the utility and effectiveness of a decision aid in cisplatin-intolerant patients with locally advanced cervical cancer. The main questions it aims to answer are: 1.
- Trial name
- CECIL (NCT05701735)
- Testing
- CECIL Patient Decision Aid
- Where
- 3 sites in Philippines
- Volunteers
- 45 people
- Sponsor
- University of Santo Tomas Hospital, Philippines
Community-dwelling Older Adults
Humanoid-Technology Driven Health Enhancing Physical Activity
Ensuring the health and well-being of older individuals is a global problem. The application of emerging technology is increasingly advocated to improve health outcomes, yet the investigators need to identify how feasible and…
- Trial name
- NCT06136468
- Testing
- Virtual coach
- Where
- 2 sites in Philippines
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Solid Tumor
Basket Trial in Solid Tumors Harboring a Fusion of FGFR1, FGFR2 or FGFR3- (FUZE Clinical Trial)
The primary objective of this study is to assess the efficacy of Debio 1347 in terms of objective response rate (ORR) in participants with solid tumors harboring fibroblast growth factor receptor (FGFR)1-3 gene…
- Trial name
- NCT03834220
- Testing
- Debio 1347
- Where
- 105 sites in United States, Australia and 21 more
- Volunteers
- 63 people
- Sponsor
- Debiopharm International SA
Serious Bacterial Infection
Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria
Phase 3 study to determine the efficacy, safety, and tolerability of aztreonam- avibactam (ATM- AVI) versus best available therapy (BAT) in the treatment of hospitalized adults with complicated intra-abdominal infections (cIAI)…
- Trial name
- NCT03580044
- Testing
- ATM-AVI, BAT
- Where
- 42 sites in United States, Argentina and 10 more
- Volunteers
- 15 people
- Sponsor
- Pfizer
Cardiovascular Diseases, Risk Factor, Cardiovascular
Prospective Urban Rural Epidemiology Study
To examine the impact of health determinants at the individual (e.g. health related behaviors) and societal level (e.g. environmental factors, health related policy, quality of health systems) on health outcomes (e.g.
- Conditions
- Cardiovascular Diseases, Risk Factor, Cardiovascular, Health Behavior, Environmental Exposure
- Trial name
- PURE (NCT03225586)
- Where
- 34 sites in Argentina, Bangladesh and 23 more
- Volunteers
- 200,000 people
- Sponsor
- Population Health Research Institute
Iron-deficiency
Alternate Day vs. Daily Iron Supplementation in Iron Depleted Women in the Philippines
Iron is very important for our body and performs vital tasks. Iron deficiency is a worldwide health problem. The prevalence of anemia in women of reproductive age in Southeast Asia is estimated to be 46.6% in 2019, with iron…
- Trial name
- NCT05280821
- Testing
- daily ferrous sulfate, alternate day ferrous sulfate
- Where
- Philippines
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Sudden Cardiac Arrest, Acute Myocardial Infarction
Improve SCA Bridge Study
The purpose of the Improve SCA Bridge study is to characterize the care pathway flow of post-acute myocardial infarction (MI) patients as a result of standard assessments of left ventricular ejection fraction (LVEF) in the acute…
- Trial name
- NCT03715790
- Testing
- EP referred group, Non-Referred group
- Where
- 52 sites in Bangladesh, Brunei and 14 more
- Volunteers
- 1,491 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Coronavirus, Severe Acute Respiratory Syndrome
Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial
ACT is a randomized clinical trial to assess therapies to reduce the clinical progression of COVID-19.
- Trial name
- ACTCOVID19 (NCT04324463)
- Testing
- Colchicine, Interferon-Beta, Aspirin
- Where
- 66 sites in Brazil, Canada and 10 more
- Volunteers
- 6,667 people
- Sponsor
- Population Health Research Institute
Carcinoma, Squamous Cell of Head and Neck
Study of Post-Op Adjuvant Concurrent Chemo-RT With or Without Nimotuzumab for Head & Neck Cancer
The aim of the study is to improve the loco-regional control rate and overall survival of locally advanced head and neck squamous carcinoma (HNSCC).
- Trial name
- NCT00957086
- Testing
- Nimotuzumab
- Where
- 30 sites in Australia, Cuba and 11 more
- Volunteers
- 710 people
- Sponsor
- National Cancer Centre, Singapore
Anaemia Associated With Chronic Kidney Disease
A Study of Efepoetin Alfa in Treating Anaemia Associated With Chronic Kidney Diseases Patient
This is an open-label, randomised, multicenter, Mircera-controlled, parallel-group, Phase III study to determine whether subcutaneous administered efepoetin alfa is as effective and well tolerated as subcutaneous Mircera for…
- Trial name
- NCT04155125
- Testing
- efepoetin alfa, Mircera
- Where
- 55 sites in Australia, Indonesia and 5 more
- Volunteers
- 391 people
- Sponsor
- PT Kalbe Genexine Biologics
COVID-19
A Trial to Investigate Recovery From COVID-19 With C21 in Adult Subjects
This trial is a randomized, double-blind, placebo-controlled, parallel-group, 2-arm, multicenter trial to evaluate the efficacy and safety of C21 versus placebo as add-on to standard of care (SoC) in adult subjects with COVID-19.
- Trial name
- ATTRACT-3 (NCT04880642)
- Testing
- C21
- Where
- 60 sites in United States, Argentina and 8 more
- Volunteers
- 272 people
- Sponsor
- Vicore Pharma AB
Hepatocellular Carcinoma (HCC)
A Phase II Open Label Study of BMS-582664 in Locally Advanced or Metastatic Hepatocellular Cancer
The purpose of this clinical research study is to learn if BMS-582664 can shrink or slow the growth of advanced liver cancer. The safety of this treatment will also be studied.
- Trial name
- NCT00355238
- Testing
- brivanib (active)
- Where
- 37 sites in United States, France and 6 more
- Volunteers
- 137 people
- Sponsor
- Bristol-Myers Squibb
Pre-Eclampsia
Implementation of First-trimester Screening and preventiOn of pREeClAmpSia Trial (FORECAST)
This implementation study aims to evaluate the efficacy, acceptability, and safety of first-trimester screening and prevention for preterm-preeclampsia.
- Trial name
- FORECAST (NCT03941886)
- Testing
- Low-dose aspirin in women with high risk of preeclampsia
- Where
- 19 sites in China, Hong Kong and 8 more
- Volunteers
- 42,454 people
- Sponsor
- Chiu Yee Liona Poon
GERD, Gastro Esophageal Reflux
Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features
Gastroesophageal reflux disease is a commonly encountered disorder in daily practice. Proton pump inhibitor therapy has been the cornerstone of treatment for decades.
- Trial name
- NCT04028466
- Testing
- Vonoprazan, Omeprazole
- Where
- Philippines
- Volunteers
- 82 people
- Sponsor
- St. Luke's Medical Center, Philippines
Diabetes, Diabetes Mellitus, Type 1
Observational Study of Safety and Tolerability of Levemir™ FlexPen™ (Insulin Detemir) in the Treatment of Type 1 and Type 2 Diabetes Mellitus
This study is conducted in Asia. The aim of this observational study is to evaluate the safety and tolerability of Levemir™ FlexPen™ (Insulin Detemir) in the treatment of Filipino patients with Type 1 and Type 2 Diabetes Mellitus.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00655200
- Testing
- insulin detemir
- Where
- Philippines
- Volunteers
- 2,286 people
- Sponsor
- Novo Nordisk A/S
Systemic Lupus Erythematosus, Active Cutaneous Lupus Erythematosus
Study to Evaluate BIIB059 (Litifilimab) in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)
The primary purpose of the study is to evaluate the efficacy of BIIB059 (litifilimab) in reducing disease activity in participants with systemic lupus erythematosus (SLE) with active cutaneous manifestations and joint involvement…
- Trial name
- LILAC (NCT02847598)
- Testing
- BIIB059 (litifilimab)
- Where
- 128 sites in United States, Argentina and 10 more
- Volunteers
- 264 people
- Sponsor
- Biogen
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