Clinical trials: in Reunion
Parodontitis, Obesity
Inflammatory Status of Visceral Adipose Tissue in Obese Patients Related to Periodontitis Severity
The research aims to compare the inflammatory status of visceral adipose tissue from obese patients depending on the presence and severity of periodontitis, in order to establish a potential causal link between the severity of…
- Conditions
- Parodontitis, Obesity, Metabolism Disorders
- Trial name
- BACTERIOB (NCT02853734)
- Testing
- SEVERE PERIODONTITIS, NO PERIODONTITIS
- Where
- Reunion
- Volunteers
- 122 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Frail Elderly Syndrome, Physical Activity
Frailty Prevention in Elders From Reunion Island
In Reunion Island, people encounter environmental and social conditions leading to premature ageing and subsequent frailty. Social welfare has developped exercise programs to promote physical activity especially for elderly with…
- Trial name
- 5P-PILOTE (NCT03271112)
- Testing
- Exercise program
- Where
- Reunion
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Endometriosis
Evaluation of a Subcutaneous Progestogen Implants in the Medical Management of Painful Endometriosis
Endometriosis is a chronic relapsing disease characterized by the presence and proliferation of endometrial glands and stroma outside the uterus.
- Trial name
- END-IMPACT (NCT02669238)
- Testing
- Nexplanon®, Minidril®/Leeloo®
- Where
- Reunion
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Surgery, Anxiety State
Efficiency of Favourite Versus Predetermined Musical Sequence on Gynecology Pre-operative Anxiety
Anxiety is a psychologic and physiological state that could be characterized by somatic, emotional, cognitive and behavioral components.
- Trial name
- MUANX (NCT03226834)
- Testing
- MUSIC CARE, PERSONAL PLAY-LIST
- Where
- Reunion
- Volunteers
- 170 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Migraine Headache
Music Intervention on Migraine Headaches
Migraine is a frequent pathology, highly linked to anxio-depressive factors. Non-drug approaches are part of the therapeutic arsenal.
- Trial name
- CHU (NCT03763058)
- Testing
- Music Therapy
- Where
- Reunion
- Volunteers
- 20 people
- Sponsor
- Association de Musicothérapie Applications et Recherches Cliniques
Pregnancy Loss, Infant Death
In-utero Death and Birth Mortality in Reunion Island
Infant mortality is still relevant despite the improvement and the accessibility of hospital care. Premature birth are two fold higher than in metropolitan France.
- Trial name
- RAMIR (NCT03354832)
- Testing
- Foetal death, New-born death, Birth control for foetal death
- Where
- Reunion
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Stroke, Acute
HDL Dysfunction During the Acute Stage of Stroke
The study investigates the effect of plasma myeloperoxidase (MPO) concentrations on HDL dysfunction during the acute stage of ischemic and haemorrhagic strokes.
- Trial name
- RUSH (NCT03245957)
- Testing
- Ischemic stroke, Haemorrhagic stroke
- Where
- Reunion
- Volunteers
- 112 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Bacterial Resistance
Community Epidemiology and Typology of Third-generation Cephalosporins Resistant Enterobacteriaceae in Reunion Island
In its report dated april 2014, World Health Organization confirms antibiotic resistance dissemination in all parts of the world, in hospitals and in community and worries about a possible comeback to a pre-antibiotic era during…
- Trial name
- AB-RUN (NCT03226314)
- Testing
- stool sample
- Where
- Reunion
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Ventilator-associated Pneumonia
Medico-economic Study of the Subglottic Secretions Drainage in Prevention of Ventilator-associated Pneumonia (DEMETER)
In France, despite the implementation of bundles to prevent Ventilator-Associated Pneumonia (VAP) in the last decades, the VAP incidence remains high above 10 per cent.
- Trial name
- DEMETER (NCT02515617)
- Testing
- Endotracheal tubes not allowing SSD, Endotracheal tubes allowing SSD
- Where
- 25 sites in Belgium, France and 2 more
- Volunteers
- 2,577 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Kidney Transplantation
Major Activation Of NCC in Graft Urinary Exosomes
Hypertension is common disorder after renal transplantation and is associated with mortality. Calcineurin Inhibitor (CNI), by activating NCC cotransporter, may be a major determinant of hypertension, included in a "Gordon like"…
- Trial name
- MANGUE (NCT03503461)
- Testing
- exosomes analysis
- Where
- 2 sites in France, Reunion
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
HIV
Practice of "Chemical Sex" by HIV Patients in Reunion Island
The term "CHEMSEX", short for "chemicals" and "sex", is used to define the consumption, regardless of the route of administration, of drugs or substances for recreational use, in a sexual context.
- Trial name
- CHEMSEX (NCT03687281)
- Testing
- Survey
- Where
- Reunion
- Volunteers
- 245 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pain Acute
Efficacy of Premixed Nitrous Oxide and Oxygen in Elderly Patient With Out-of-hospital Severe Acute Pain
Pain in the elderly is poorly evaluated and clearly under treated. Premixed nitrous oxide and oxygen is used in the emergency medical care of the trauma, burns, during transport of patient with pain.
- Trial name
- MEOPA-PA (NCT01990404)
- Testing
- Premixed 50% nitrous oxide and oxygen, Medical Air
- Where
- 3 sites in France, Reunion
- Volunteers
- 43 people
- Sponsor
- University Hospital, Toulouse
Acute Coronary Syndrome
Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.
In the management of acute coronary syndromes with ST-segment elevation (STEMI), early analgesia reduces the effects of hyperadrenalism which increases the size of myocardial infarction.
- Trial name
- SCADOLII (NCT02198378)
- Testing
- MEOPA and paracetamol, Morphine
- Where
- 40 sites in France, Reunion
- Volunteers
- 680 people
- Sponsor
- University Hospital, Toulouse
Unverricht-Lundborg Disease
Brivaracetam as add-on Treatment of Unverricht-Lundborg Disease in Adolescents and Adults
The study will compare the efficacy and safety of brivaracetam with placebo in patients with Unverricht-Lundborg disease.
- Trial name
- NCT00357669
- Testing
- Brivaracetam 25 mg, Brivaracetam 50 mg
- Where
- 13 sites in Finland, France and 5 more
- Volunteers
- 50 people
- Sponsor
- UCB Pharma SA
Head and Neck Neoplasms, Neoplasm Recurrence, Local
Taxotere (Docetaxel) in 1st Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
The purpose of the study is to compare time to progression and overall survival after treatment with Taxotere plus cisplatin versus cisplatin plus 5-FU (PF treatment group) in the first line treatment of patients with recurrent…
- Conditions
- Head and Neck Neoplasms, Neoplasm Recurrence, Local, Neoplasm Metastasis
- Trial name
- NCT00401323
- Testing
- docetaxel (XRP6976), cisplatin, 5-fluorouracil (5-FU)
- Where
- 20 sites in United States, Argentina and 18 more
- Volunteers
- 568 people
- Sponsor
- Sanofi