Clinical trials: open to volunteers, in Senegal
Pneumonia, Pneumonia Childhood
Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia - ToolCAP
The ToolCAP study aims to see if using ultrasound to look at the lungs when children have symptoms of a lung infection will safely allow doctors to improve how they treat those infections.
- Conditions
- Pneumonia, Pneumonia Childhood, Pneumonia - Bacterial, Pediatrics
- Trial name
- ToolCAP (NCT06670833)
- Testing
- Lung ultrasound, Standard of Care (SOC)
- Where
- 9 sites in Senegal, South Africa and 1 more
- Volunteers
- 4,894 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Preeclampsia
Optimizing the Use of Aspirin for the Prevention of Preeclampsia
Pregnant women at higher risk for preeclampsia (PE) are currently recommended to take low-dose aspirin (acetylsalicylic acid, ASA) daily from the first trimester until 36 weeks of gestation.
- Trial name
- Optim-PRE (NCT07665853)
- Testing
- Discontinuation of Acetylsalicilic acid 150 mg/day at 24-28 weeks of gestation
- Where
- 38 sites in Austria, Bulgaria and 5 more
- Volunteers
- 15,160 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Cervical Cancer, Behavior
Adaptation and Implementation of a Patient Navigation Program for Cervical Cancer Screening Across Contexts in Senegal
The goal of this project is to prevent unnecessary deaths due to cervical cancer in Senegal. This mixed methods research responds to identified intrapersonal- and community-level barriers to early cervical cancer screening…
- Trial name
- NCT05544084
- Testing
- Patient Navigator Approach
- Where
- Senegal
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Skin and Connective Tissue Diseases, Neglected Tropical Diseases
Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers
Skin-related Neglected Tropical Diseases (Skin NTDs) affect about 1.8 billion people worldwide, particularly in poor and rural communities where healthcare access is limited.
- Conditions
- Skin and Connective Tissue Diseases, Neglected Tropical Diseases, Leprosy, Buruli Ulcer
- Trial name
- SkincAIr (NCT07506967)
- Testing
- A mobile app with AI functionality for diagnosing skin-related NTDs
- Where
- 5 sites in Democratic Republic of the Congo, Ethiopia and 3 more
- Volunteers
- 2,420 people
- Sponsor
- Kenya Medical Research Institute
Retinoblastoma
Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma
As the survival of children with retinoblastoma in high income countries is higher than 95% including the bilateral forms this study hopes to improve the outcome in low income countries in Africa by improving early diagnosis and…
- Trial name
- GFARB12019 (NCT04425434)
- Testing
- OBSERVATIONAL
- Where
- 7 sites in Burkina Faso, Côte d’Ivoire and 4 more
- Volunteers
- 3,000 people
- Sponsor
- French Africa Pediatric Oncology Group
Burkitt Lymphoma
Recommendations for the Treatment of Children With Burkitt's Lymphoma
This is the 4th LMB study by the French African Pediatric Oncology Group (GFAOP). The study hopes to be able to evaluate children earlier with stage I and II disease and to evaluate treatment response earlier so that the units…
- Trial name
- GFALMB2019 (NCT04425421)
- Testing
- OBSERVATIONAL
- Where
- 7 sites in Burkina Faso, Côte d’Ivoire and 4 more
- Volunteers
- 1,000 people
- Sponsor
- French Africa Pediatric Oncology Group
Nephroblastoma
Therapeutic Recommendations for Nephroblastoma
The study is based on results form 2 previous studies carried out by the GFAOP. The aim of this study is to evaluate the capacity of units to follow the recommendations in the protocol.
- Trial name
- GFANEPHRO20 (NCT04423484)
- Testing
- Data collection
- Where
- 7 sites in Burkina Faso, Côte d’Ivoire and 4 more
- Volunteers
- 1,000 people
- Sponsor
- French Africa Pediatric Oncology Group
Childhood ALL
Recommendations for the Treatment of Children With Acute Lymphoblastic Leukemia in the GFAOP
The LALGFA2019 Recommendations redefine the standard risk criteria and propose to introduce anthracycline induction in so-called high-risk forms (LAL line T and LAL line B with leukocytosis greater than or equal to 50 G/L or in…
- Trial name
- LALGFA2019 (NCT04794296)
- Where
- 3 sites in Côte d’Ivoire, Guinea and 1 more
- Volunteers
- 500 people
- Sponsor
- French Africa Pediatric Oncology Group
Pediatric Cancer
Hospital Based Registry of Childhood Cancer in Pediatric Oncology Units in French Speaking Africa
The ultimate aim of this registry is to collect precise information concerning the children coming to oncology units working with the French African Oncology Group.
- Trial name
- RFAOP (NCT03803735)
- Where
- 14 sites in Burkina Faso, Cameroon and 10 more
- Volunteers
- 10,000 people
- Sponsor
- French Africa Pediatric Oncology Group
Coverage of Vitamin A Supplementation, Coverage of Immunization
OPTIMIZING ROUTINE DELIVERY OF ESSENTIAL CHILD HEALTH AND NUTRITION PACKAGE THROUGH PRIMARY HEALTH CARE CONTACTS
The primary objective of the study is to assess whether optimization of an essential package of health and nutrition services for children under five years of age using vitamin A supplementation touch points (i.e., the…
- Conditions
- Coverage of Vitamin A Supplementation, Coverage of Immunization, Feasibility and Fidelity of Implementation
- Trial name
- NCT06949930
- Testing
- Optimized package of child essential health and nutrition services, Standard package of essential child and nutrition services
- Where
- 2 sites in Kenya, Senegal
- Volunteers
- 1,928 people, healthy volunteers welcome
- Sponsor
- Nutrition International
STEMI, Remote Ischaemic Conditioning
Remote Ischaemic Conditioning in STEMI Patients in AFRICA
The RIC-AFRICA trial is a multi-centre, sham-controlled, randomised controlled trial (RCT) involving 1400 ST-segment elevation myocardial infarction (STEMI) patients presenting within ≤ 24 hours of myocardial infarction (MI)…
- Conditions
- STEMI, Remote Ischaemic Conditioning, Myocardial Reperfusion Injury
- Trial name
- RIC-AFRICA (NCT04813159)
- Testing
- Remote Ischaemic Conditioning (RIC)
- Where
- 20 sites in Kenya, Mozambique and 4 more
- Volunteers
- 1,400 people
- Sponsor
- University of Cape Town