Clinical trials: completed, in Slovakia
Burnout, Professional, Mental Health
Mental Health Resources and Employability in Healthcare
This interventional study evaluates the effectiveness of two 8-week self-regulation training programs (coaching-based and mindfulness-based) designed to enhance mental health and employability resources among healthcare workers…
- Conditions
- Burnout, Professional, Mental Health, Emotional Regulation, Occupational Stress
- Trial name
- NCT07465809
- Testing
- Coaching-Based Self-Regulation Training, Mindfulness training program
- Where
- Slovakia
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Comenius University
Healthy Adult Male
Effects of Caffeine on Agility in Amateur Soccer Players
This randomized, double-blind, placebo-controlled crossover clinical trial aims to investigate the acute effects of caffeine supplementation on motor and perceptual-cognitive components of agility performance in male amateur…
- Trial name
- NCT07844122
- Testing
- Caffeine 300 MG
- Where
- Slovakia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Comenius University
Pudendal Neuralgia- Physiotherapy
Exercise Program in Women With Pudendal Neuralgia
This randomized controlled trial compares a 6-month physiotherapy exercise program versus no structured exercise intervention in women with pudendal neuralgia.
- Trial name
- ELASTIN (NCT07446556)
- Testing
- Pelvic Floor Relaxation Protocol
- Where
- Slovakia
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Comenius University
Vegan Diet, Body Composition
Acute Metabolic Response Versus Long-term Adaptation to a Vegan Diet
At baseline, venous blood samples were collected from all eligible participants. The following biochemical parameters were analysed: serum electrolytes (mineral profile), fasting glucose, creatinine, urea nitrogen, total…
- Conditions
- Vegan Diet, Body Composition, Quality of Life (QOL), Cardiometabolic Health
- Trial name
- VITAL (NCT07731633)
- Testing
- vegan diet
- Where
- Slovakia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Martin
Severe Hepatic Impairment, Healthy
PK Study in Subjects With Severe Hepatic Impairment
This is an open-label, single-dose study in male and female subjects with severe hepatic impairment and in male and female subjects with normal hepatic function.
- Trial name
- MCI-186-E05 HP (NCT03664544)
- Testing
- MCI-186
- Where
- 3 sites in Czechia, Hungary and 1 more
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Shionogi
Pudendal Nerve, Healthy Women
Pelvic Floor Shear-Wave Elastography in Healthy and Pudendal Neuralgia Women
This study will compare superficial pelvic floor shear-wave elastography between healthy women and women with pudendal neuralgia.
- Trial name
- ELANEP (NCT07458737)
- Testing
- Pelvic floor shear wave elastography, Pelvic Floor Impact Questionnaire-Short Form 7 (PFIQ-7), Female Sexual Distress Scale-Revised (FSDS-R)
- Where
- Slovakia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Comenius University
Anorexia Nervosa, Sexual Function
Female Sexual Dysfunction and Anorexia Nervosa
The objective of this observational study is to investigate the potential influence of anorexia nervosa on the sexual health of women.
- Conditions
- Anorexia Nervosa, Sexual Function, Woman
- Trial name
- SD&AN (NCT06253403)
- Testing
- psychotherapy
- Where
- Slovakia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Comenius University
Hepatic Impairment
A Study About Fazirsiran in People With and Without Liver Problems
The main aim of this study is to learn how the body processes fazirsiran (pharmacokinetics [PK]) in people with mild, moderate, or severe liver problems, compared to people with normal liver function.
- Trial name
- NCT05891158
- Testing
- Fazirsiran
- Where
- 4 sites in Hungary, Slovakia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Takeda
Immunity, Cytokine Levels
Analysis of Psychoneuroimmunological Parameters of Health in Specific Population Groups in Slovakia
This study aims to investigate the links between psychological and biological immunity from the perspective of psychology, epidemiology, and immunology in a general population study sample as well as in a specific group of people…
- Conditions
- Immunity, Cytokine Levels, Psychological Adaptation, Resilience
- Trial name
- APNIP (NCT07070180)
- Where
- 3 sites in Slovakia
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Comenius University
Depression Disorders, Bipolar Affective Disorder
Epidemiological Study on the Prevalence of Mental Disorders in Slovakia
This study maps the current epidemiological situation of mental disorders in Slovakia. The aim of the study is to determine the prevalence of selected mental disorders in the adult population of the Slovak Republic, assess the…
- Conditions
- Depression Disorders, Bipolar Affective Disorder, Generalized Anxiety Disorder (GAD), Panic Disorder
- Trial name
- EpiMentDisSK (NCT07129408)
- Where
- Slovakia
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Comenius University
STIs, HIV
Prevalence of HIV and Sexually Transmitted Infections in Migrant Communities in Slovakia
Before project launch, key materials were prepared, including informed consents, posters, informational leaflets, patient cards, social media posts, standard operating procedures, patient management plans and patient registries.
- Conditions
- STIs, HIV, Rapid Detection
- Trial name
- NCT07236268
- Where
- Slovakia
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Comenius University
Hepatic Impairment, Healthy Volunteers
A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function
The study medicine NNC0194-0499 is under development for non-alcoholic fatty liver disease (NAFLD) including non-alcoholic steatohepatitis (NASH).
- Trial name
- NCT05917938
- Testing
- NNC0194-0499
- Where
- 5 sites in Germany, Poland and 1 more
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Emotionality, Anxiety
Impact of Snoezelen Intervention and Reminiscence Therapy on Seniors' Emotionality and Anxiety
The aim of the study is to verify and compare the short-term and long-term effectiveness (retention) of Snoezelen intervention and reminiscence therapy and to analyze the dynamics of changes in the level of emotionality and…
- Trial name
- NCT07374887
- Testing
- Reminiscence therapy, Snoezelen intervention
- Where
- Slovakia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Matej Bel University
Pre-term Infant
Growth and Safety of Two Partially-hydrolyzed Feeding Systems for Preterm Infants
This is an open-label trial consisting of two sub-studies to be conducted sequentially with the purpose of evaluating the safety and suitability of a two feeding systems in pre-term infants (one containing HMOs and one without…
- Trial name
- NCT04639518
- Testing
- Preterm formulas with HMO, Preterm formulas without HMO
- Where
- 4 sites in Germany, Poland and 1 more
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Breast Neoplasms, Breast Cancer Detection
Diagnostic Accuracy of Carebot AI MMG in Mammography Screening: Multicenter MRMC Study
This study evaluates the diagnostic performance of Carebot AI MMG, an artificial intelligence (AI)-enabled medical device for evaluating mammograms.
- Conditions
- Breast Neoplasms, Breast Cancer Detection, Breast Cancer - Female, Breast Cancer Screening
- Trial name
- CARE-MMG-MRMC (NCT07298252)
- Testing
- Carebot AI MMG software analysis
- Where
- 4 sites in Czechia, Slovakia
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Carebot s.r.o.
Hepatic Impairment, Healthy Volunteers
A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the Body
The study is divided into two parts - Part A and Part B. Cagrilintide in combination with semaglutide, is under development for weight management.
- Trial name
- NCT05564104
- Testing
- Cagrilintide
- Where
- 4 sites in Czechia, Germany and 1 more
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Hepatic Impairment
A Phase 1 Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function
The primary objective is to assess the pharmacokinetics (PK) of apraglutide in subjects with hepatic impairment compared with matched control subjects with normal hepatic function following single subcutaneous (SC) dose…
- Trial name
- NCT05706623
- Testing
- Apraglutide
- Where
- 2 sites in Germany, Slovakia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VectivBio AG
Subjective Cognitive Impairment, Mild Cognitive Impairment
Molecular Mediators of Physical Exercise and Carnosine Induced Effects in Patients With Preclinical and Early Stage Neurodegenerative Disease
The purpose of this study is to investigate the beneficial effects of regular exercise and the impact of food supplement carnosine on cognitive, motoric and metabolic functions as well as on specific biologically active…
- Conditions
- Subjective Cognitive Impairment, Mild Cognitive Impairment, Parkinson Disease, Healthy Volunteers
- Trial name
- NCT03330470
- Testing
- exercise, carnosine supplementation, stretching
- Where
- 3 sites in Slovakia, Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
Hepatic Impairment
Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects
This will be a Phase I, multicentre, single-dose, non-randomized, open-label, parallel-group study to examine the PK, safety, and tolerability of camizestrant 75 mg in post-menopausal female participants with moderate or severe…
- Trial name
- NCT05790304
- Testing
- Camizestrant
- Where
- 4 sites in United States, Bulgaria and 1 more
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Emotional States, Loneliness
Activation Programme's Impact on Seniors' Emotionality and Loneliness
The goal of this pilot study is to verify the short-term effectiveness of the Activation-Socialisation Intervention Programme (A-S IP) on the psychosocial survival of older adults in a specific care facility.
- Conditions
- Emotional States, Loneliness, Seniors
- Trial name
- NCT06866015
- Testing
- Activation-socialization intervention programme
- Where
- Slovakia
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Diana Ďuricová