Clinical trials: in Sudan
Dermatological Disorders
Assessment of Knowledge, Attitude and Practice of Primary Care Doctors Towards Common Dermatologic Conditions in Sudan
The goal of this observational study is to assess the knowledge, attitude, and practice of primary care physicians regarding the common dermatologic conditions in Sudan.
- Trial name
- NCT06664489
- Where
- Sudan
- Volunteers
- 178 people
- Sponsor
- Afifa Muhammad Alameen Khalifa Alshaykh
Eumycetoma
Eumycetoma Long-term Post-Treatment Follow-Up Study
To assess the long-term recurrence rate of eumycetoma in clinical trial participants treated in the phase II DNDi-FOSR-04-MYC clinical trial.
- Trial name
- NCT06514183
- Testing
- Clinical diagnosis of recurrence
- Where
- Sudan
- Volunteers
- 51 people
- Sponsor
- Drugs for Neglected Diseases
Mycetoma
Proof-of-Concept Superiority Trial of Fosravuconazole Versus Itraconazole for Eumycetoma in Sudan
This study is a single-center, comparative, randomized, double-blind, parallel-group, active-controlled, clinical superiority trial of Fosravuconazole versus Itraconazole combined with surgery in subjects with eumycetoma in…
- Trial name
- NCT03086226
- Testing
- Fosravuconazole, Itraconazole
- Where
- Sudan
- Volunteers
- 104 people
- Sponsor
- Drugs for Neglected Diseases
Incidence of Thyroid Cancer in Long Standing MNG
Risk of Malignancy in Endemic Long Standing Nodular Goitres: a Prospective Cohort Study
To determine the incidence of thyroid cancer in patients with long standing goitres presenting for surgery.
- Trial name
- NCT06405919
- Testing
- Histopathology
- Where
- Sudan
- Volunteers
- 160 people
- Sponsor
- University of Khartoum
Hepatitis B, Hepatitis D
Prevalence and Clinical Characterization of Hepatitis D Virus (HDV) Infection Among Sudanese Patients With Hepatitis B Virus
Background: Sudan has a high prevalence of hepatitis B surface antigen (HBsAg), exceeding 8%. The prevalence of hepatitis B varies across different regions of Sudan, ranging from 6.8% in central Sudan to as high as 26% in…
- Conditions
- Hepatitis B, Hepatitis D, Viral Hepatitis
- Trial name
- NCT06360484
- Testing
- investigations for Hepatitis D virus
- Where
- Sudan
- Volunteers
- 90 people
- Sponsor
- National Center for Gastroentestinal and Liver Disease
Critical Illness, Mortality
The African Critical Illness Outcomes Study
In Africa, the prevalence of critical illness is likely to be higher due to a greater burden of disease, and the associated mortality higher due to limited resources.
- Trial name
- ACIOS (NCT06051526)
- Where
- Sudan
- Volunteers
- 20,159 people
- Sponsor
- University of Cape Town
Visceral Leishmaniasis
Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa
This is an open label, Phase III, randomized, controlled, parallel arm multicentre non-inferiority clinical trial to compare the efficacy and safety of two combination regimens of Miltefosine and Paromomycin with the standard…
- Trial name
- NCT03129646
- Testing
- Miltefosine, Paromomycin, Sodium stibogluconate
- Where
- 7 sites in Ethiopia, Kenya and 2 more
- Volunteers
- 439 people
- Sponsor
- Drugs for Neglected Diseases
General Surgery
Outcome of Laparoscopic Appendicectomy Versus Open Appendicectomy in Sudanese Patients
Background: Laparoscopic appendectomy as a minimal invasive procedure had low morbidity and mortality. It affords a direct diagnosis of the problem, allows determination of the appropriate treatment.
- Trial name
- NCT06158308
- Testing
- Laproscopic Appendicectomy, Open Appendicectomy
- Where
- Sudan
- Volunteers
- 340 people
- Sponsor
- National Center for Gastroentestinal and Liver Disease
Urinary Bladder Cancer
Patterns of Urinary Bladder Cancer in Darfur, Suda
Background: Bladder cancer (BC) exhibits extreme heterogeneity regarding clinical outcome, etiology, histology, and geographic distribution.
- Trial name
- NCT06156787
- Where
- Sudan
- Volunteers
- 105 people
- Sponsor
- National Center for Gastroentestinal and Liver Disease
Pancreatic Cancer, Ampullary Cancer
Recurrence After Whipple's (RAW) Study
Pancreatic head malignancies are aggressive cancers that are often inoperable when they are diagnosed. In the ~20% of patients who are diagnosed when the disease is still operable, surgery is the only treatment that can provide a…
- Conditions
- Pancreatic Cancer, Ampullary Cancer, Bile Duct Cancer, Cholangiocarcinoma, Extrahepatic
- Trial name
- NCT04596865
- Testing
- Pancreaticoduodenectomy
- Where
- 29 sites in Australia, Austria and 6 more
- Volunteers
- 1,484 people
- Sponsor
- University Hospital Plymouth NHS Trust
Malaria
Automated Microscopy Evaluation Study
Since the introduction of Giemsa stain in 1904 until today, malaria microscopy has been the standard of practice for malaria diagnosis.
- Trial name
- AutoMic (NCT04558515)
- Testing
- Novel malaria diagnostics & tools
- Where
- Sudan
- Volunteers
- 190 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Malaria, Diagnoses Disease
RapiGEN BIOCREDIT Malaria Ag RDTs WHO Prequalification Study
Since their introduction in the late 90's, rapid diagnostic tests (RDTs) have markedly improved our ability to control malaria; yet they have inherent limitations which include low sensitivity in Plasmodium vivax detection and…
- Conditions
- Malaria, Diagnoses Disease, RDT
- Trial name
- NCT05085301
- Testing
- Rapid diagnostic test
- Where
- 2 sites in Indonesia, Sudan
- Volunteers
- 674 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Malaria, RDT
Abbott NxTekTM Malaria RDT WHO Prequalification Study
Since their introduction in the late 90's, rapid diagnostic tests (RDTs) have dramatically improved our ability to control malaria but proved insufficient to support elimination efforts because of their limited sensitivity…
- Conditions
- Malaria, RDT, Diagnoses Disease
- Trial name
- NCT05444790
- Testing
- Rapid Diagnostic Test
- Where
- 3 sites in Indonesia, Peru and 1 more
- Volunteers
- 4,563 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Leishmaniasis, Cutaneous
A Study to Assess the Safety, Efficacy and Immunogenicity of Leishmania Vaccine ChAd63-KH in PKDL
This trial is designed to assess the therapeutic efficacy and safety of CHAd63-KH, a new candidate Leishmania vaccine, in patients with persistent PKDL.
- Trial name
- NCT03969134
- Testing
- ChAd63-KH
- Where
- Sudan
- Volunteers
- 86 people
- Sponsor
- University of York
COVID-19, Cardiovascular Diseases
WORLD HEART FEDERATION (WHF) COVID-19 and Cardiovascular Disease Survey
A global study for a better understanding of the cardiovascular conditions that increase the risk of developing severe COVID-19, and a better characterization of cardiovascular complications in hospitalized patients with COVID-19.
- Trial name
- WHF (NCT04475471)
- Where
- 32 sites in Argentina, Bangladesh and 15 more
- Volunteers
- 5,200 people
- Sponsor
- Public Health Foundation of India
Rheumatic Heart Disease
INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority
This program is a comprehensive evaluation of rheumatic valvular heart disease (RVHD), Atrial fibrillation (AF)/flutter and stroke.
- Trial name
- INVICTUS-VKA (NCT02832544)
- Testing
- Rivaroxaban (20 mg), Vitamin K antagonists (VKA)
- Where
- 139 sites in Botswana, Brazil and 23 more
- Volunteers
- 4,565 people
- Sponsor
- Population Health Research Institute
Dental Caries in Children
The Impact of School Teachers in Care Navigation and Signposting Dental Caries in Primary School Children
The study aims to investigate the role of school teachers in care navigation and signposting dental caries in primary school children.
- Trial name
- NCT04945252
- Testing
- Signpost caries
- Where
- Sudan
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Khartoum Centre for Research and Medical Training
Acute Appendicitis
Modification and Validation of the RIPASA Score for Diagnosis of Acute Appendicitis
Purpose: The diagnostic approach of patients with acute appendicitis (AA) remains debated. A number of clinical prediction rules (CPRs) exist for diagnosis of AA with variable sensitivity, specificity, and diagnostic accuracy, in…
- Trial name
- MODRIS (NCT04207645)
- Testing
- Modified RIPASA score
- Where
- 37 sites in India, Mexico and 4 more
- Volunteers
- 240 people
- Sponsor
- Soba University Hospital
Gastric Cancer, Non-Atrophic Gastritis
Helicobacter Pylori Genome Project (HpGP)
Helicobacter pylori is a common bacterial infection. It can lead to severe stomach problems, including stomach cancer. Researchers want to look at samples of the bacteria. These H.
- Conditions
- Gastric Cancer, Non-Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT02788214
- Where
- 94 sites in United States, Algeria and 51 more
- Volunteers
- 1,000 people
- Sponsor
- National Cancer Institute (NCI)
Mycetoma
Tissue Microenvironment Signatures of the Mycetoma Granuloma
Mycetoma is the most neglected of the neglected tropical diseases. It is caused by certain fungi or bacteria. It is endemic in many tropical and subtropical regions and Sudan seems to be the mycetoma homeland.
- Trial name
- NCT04401969
- Where
- Sudan
- Volunteers
- 28 people
- Sponsor
- University of Khartoum