Clinical trials: in Sudan
COVID 19
Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients
To study the efficacy of Gum Arabic as an immuno modulator and anti-inflammatory agent among COVID 19 seropositive patients..Half of participants will receive Gum Arabic and the other half will receive placebo
- Trial name
- GA&COVID19 (NCT04381871)
- Testing
- Acacia Senegal, Pectin
- Where
- 2 sites in Sudan
- Volunteers
- 110 people
- Sponsor
- Al-Neelain University
Sickle Cell Anemia in Children
Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia Patients
To study the efficacy of Gum Arabic as an anti-oxidant, anti-inflammatory and Fetal Hemoglobin-inducing agent among Sickle Cell Disease children. Half of participants will receive Gum Arabic and the other half will receive placebo
- Trial name
- GA&SCA (NCT04191213)
- Testing
- Acacia Senegal extract, Pectin
- Where
- Sudan
- Volunteers
- 100 people
- Sponsor
- Al-Neelain University
Leishmaniasis, Cutaneous
A Study of a New Leishmania Vaccine Candidate ChAd63-KH
This is a study to assess the safety of a new candidate Leishmania vaccine ChAd63-KH in patients with persistent post kala azar dermal leishmaniasis (PKDL).
- Trial name
- Leish2a (NCT02894008)
- Testing
- ChAd63-KH
- Where
- Sudan
- Volunteers
- 24 people
- Sponsor
- University of York
Polycystic Ovary Syndrome
Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome
To assess the effects on hormonal and metabolic changes in the PCOs patients after ingestion of Arabic gum
- Trial name
- GA&PCO (NCT04215380)
- Testing
- Acacia Senegal extract, Pectin
- Where
- Sudan
- Volunteers
- 60 people
- Sponsor
- Lamis Kaddam
PKDL - Post-Kala-Azar Dermal Leishmanioid
Short Course Regimens for Treatment of PKDL (Sudan)
This is an open label, randomized non comparative phase II clinical trial conducted on parallel groups, to assess the safety and efficacy of the combination of Paromomycin (20 mg/kg/d) IM for 14 days and Miltefosine (allometric…
- Trial name
- NCT03399955
- Testing
- Paromomycin, Ambisome, Miltefosine
- Where
- Sudan
- Volunteers
- 110 people
- Sponsor
- Drugs for Neglected Diseases
Hepatocellular Carcinoma
Combined Ipsilateral Liver Lobe Devascularization and Alcohol Treatment of the Large Hepatocellular Carcinoma
Assessment of the long-term outcome of combined ipsilateral liver lobe devascularization (ILAD) and alcohol injection of the large hepatocellular carcinoma (HCC): single center non-randomized trial.
- Trial name
- NCT03138044
- Testing
- Combined Treatment
- Where
- Sudan
- Volunteers
- 12 people
- Sponsor
- The National Ribat University
Hepatocellular Carcinoma Non-resectable
Percutaneous Ethanol Alcohol Injection for the Large and Unresectable Hepatocellular Carcinoma
Assessment of the long-term outcome of percutaneous ethanol alcohol injection (PEI) for the large and unresectable hepatocellular carcinoma: single center non-randomized trial.
- Trial name
- NCT03138031
- Testing
- Percutaneous ethanol alcohol injection
- Where
- Sudan
- Volunteers
- 23 people
- Sponsor
- The National Ribat University
Kidney Failure, Chronic
Effects of Gum Arabic Supplementation in Hemodialysis Patients
Gum Arabic is a naturally produced gummy exudate from Acacia Senegal tree. It's a complex polysaccharide with proven prebiotic properties.
- Trial name
- NCT03789708
- Testing
- Gum Arabic
- Where
- Sudan
- Volunteers
- 80 people
- Sponsor
- University of Khartoum
Kidney Transplant Rejection
Antithymocyte Globulin and Azathioprine Versus Basiliximab and Mycophenolate Mofetil in Living Donor Kidney Transplantation
Kidney transplantation is the best available treatment option for patients with end stage renal disease. However, kidney transplantation requires life-long use of immunosuppressive medication.
- Trial name
- NCT03789006
- Testing
- Antithymocyte Immunoglobulin (Rabbit), Interleukin 2 Receptor Antagonist
- Where
- Sudan
- Volunteers
- 300 people
- Sponsor
- University of Khartoum
Heart Failure, Influenza
Influenza Vaccine To Prevent Adverse Vascular Events (RCT-IVVE)
A multi-centre, randomized, placebo controlled, trial. Participants at high-risk for vascular events from the network of INTER- CHF will be randomized to inactivated influenza vaccine or placebo and followed prospectively over…
- Trial name
- RCT-IVVE (NCT02762851)
- Testing
- Sterile saline, inactivated trivalent influenza vaccine
- Where
- 13 sites in Cameroon, China and 11 more
- Volunteers
- 5,000 people
- Sponsor
- McMaster University
Hepatocellular Carcinoma
Ipsilateral Liver Lobe Devascularization of the Large Hepatocellular Carcinoma
Assessment of short-term outcomes of ipsilateral lobe arterial devascularization of the large hepatocellular carcinoma: single center non-randomized trial.
- Trial name
- NRU (NCT03129685)
- Testing
- HALED
- Where
- Sudan
- Volunteers
- 12 people
- Sponsor
- The National Ribat University
Acute Coronary Syndrome, Heart Failure
A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa
FEVRIER study is an observatory of hospitalizations in cardiology units in sub-Saharan Africa.
- Conditions
- Acute Coronary Syndrome, Heart Failure, Syncope, Stroke
- Trial name
- FEVRIER (NCT03231449)
- Testing
- observation of current care
- Where
- 20 sites in Benin, Burkina Faso and 11 more
- Volunteers
- 5,000 people
- Sponsor
- Cardiologie et Développement
Pre-Eclampsia
Safety and Efficacy of Twelve Hours Duration of MgSO4 in the Treatment of Eclampsia in Low Resource Setting in Sudan
the investigators assume that magnesium sulphate for treating eclampsia can be safely reduced from 24 hours to shorter duration of therapeutic anticonvulsant effect for 12 hours.
- Trial name
- NCT03112551
- Testing
- Adminstration of magnesium Sulphate for treatment of eclampsia
- Where
- Sudan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gadarif University
Polycystic Ovary Syndrome
The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome
An open clinical trial
- Trial name
- FolicacidPCOS (NCT03268733)
- Testing
- Folic Acid
- Where
- Sudan
- Volunteers
- 90 people
- Sponsor
- University of Khartoum
End-Stage Renal Disease
Gum Arabic as Antioxidant and Anti-inflammatory in Hemodialysis Patients
Oxidative processes increased in patients with renal failure and especially patients with end stage renal failure on dialysis. Oxidative stress plays a role in renal damage and also on cardiovascular disease, atherosclerosis…
- Trial name
- GA&CRF (NCT03214692)
- Testing
- Gum Arabic
- Where
- Sudan
- Volunteers
- 50 people
- Sponsor
- Lamis Kaddam
Primary Visceral Leishmaniasis
Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern Africa
This study is to assess if shorter combinations of SSG plus single dose AmBisome®, Miltefosine plus single dose AmBisome® and Miltefosine alone are effective in treating visceral leishmaniasis in Eastern Africa.
- Trial name
- NCT01067443
- Testing
- Liposomal amphotericin B (AmBisome®) and sodium stibogluconate, Liposomal amphotericin B + miltefosine, Miltefosine
- Where
- 3 sites in Kenya, Sudan
- Volunteers
- 151 people
- Sponsor
- Drugs for Neglected Diseases
Malaria
A Study to Assess Current Standard Malaria Treatment Guidelines in the Republic of the Sudan
This is a randomized controlled trial to assess the efficacy and safety of the national malaria treatment guidelines, asses the efficacy and safety of artesunate and sulphadoxine - pyrimethamine (AS+SP) for treatment in…
- Trial name
- MalTreSu (NCT02592408)
- Testing
- ASP, SDPQ, 14DPQ
- Where
- 2 sites in Sudan
- Volunteers
- 320 people
- Sponsor
- Menzies School of Health Research
Visceral Leishmaniasis, Human African Trypanosomiasis
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)
Tropical fevers have been a diagnostic challenge from the antiquity. Nowadays, despite the availability of good diagnostic capacities, undifferentiated febrile illnesses continue to be a thorny problem for travel physicians.
- Conditions
- Visceral Leishmaniasis, Human African Trypanosomiasis, Enteric Fever, Melioidosis
- Trial name
- NCT01766830
- Testing
- rk28 ICT, IT LEISH (rK39), Immunochromatographic HAT test
- Where
- 7 sites in Cambodia, Democratic Republic of the Congo and 2 more
- Volunteers
- 1,927 people
- Sponsor
- University Hospital, Geneva
Rheumatoid Arthritis
Gum Arabic as Immunomodulator In Rheumatoid Arthritis Patients
Gum Arabic (GA) rich dietary fiber it is a water-soluble dietary fiber derived from the dried gummy exudates of the stems and branches of Acacia senegal, GA found to have strong immuno modulator in vitro where it increased IL10…
- Trial name
- NCT02804581
- Testing
- Gum Arabic
- Where
- Sudan
- Volunteers
- 45 people
- Sponsor
- Lamis Kaddam
Visceral Leishmaniasis
Efficacy/Safety of Sodium Stibogluconate (SSG) Versus Paromomycin (PM) and SSG/PM Combination to Treat V Leishmaniasis
The purpose of this study is to assess the efficacy and safety of SSG 30 days alone, PM 21 days alone and SSG and PM as a combination course of 17 days in the treatment of patients with VL.
- Trial name
- NCT00255567
- Testing
- Sodium Stibogluconate, Paromomycin sulphate, SSG and Paromomycin sulphate
- Where
- 5 sites in Ethiopia, Kenya and 2 more
- Volunteers
- 1,142 people
- Sponsor
- Drugs for Neglected Diseases