Clinical trials: in Sudan
Visceral Leishmaniasis
Open-Label, Sequential Step, Safety and Efficacy Study to Determine the Optimal Single Dose of Ambisome for Patients With VL
This is a phase II/III open, comparative dose trial to find the lowest single dose of AmBisome for the treatment of primary, symptomatic visceral leishmaniasis(VL), in HIV negative patients.
- Trial name
- NCT00832208
- Testing
- Liposomal amphotericin B (Ambisome)
- Where
- 3 sites in Ethiopia, Sudan
- Volunteers
- 124 people
- Sponsor
- Drugs for Neglected Diseases
Visceral Leishmaniasis
Trial to Determine Efficacy of Fexinidazole in Visceral Leihmaniasis Patients in Sudan
This study is designed to determine the efficacy of Fexinidazole as an oral treatment in Visceral Leishmanisasis sudanese adults patients.
- Trial name
- NCT01980199
- Testing
- Fexinidazole
- Where
- Sudan
- Volunteers
- 14 people
- Sponsor
- Drugs for Neglected Diseases
Sickle Cell Anemia
Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia
The purpose of this study is to determine whether Gum Arabic is effective as fetal hemoglobin inducing agent for sickle cell anemia patients.
- Trial name
- NCT02467257
- Testing
- Gum Arabic
- Where
- Sudan
- Volunteers
- 47 people
- Sponsor
- Al-Neelain University
Type 2 Diabetes Mellitus
Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus
Null hypothesis: No significant effect of vitamin C 500 mg Supplementation on the severity of micro-vascular complications of type 2 Diabetes Mellitus (DM).
- Trial name
- Vit C (NCT01319734)
- Testing
- Vitamin C, glyburide
- Where
- Sudan
- Volunteers
- 50 people
- Sponsor
- Al-Neelain University
Tuberculosis
The Impact of Involving Informal Health Providers for Tuberculosis Control in Sudan
Training and engaging of unpaid informal providers (such as tea-sellers, women's groups, youth clubs, small traders and religious groups) from poorer localities in TB disease recognition, referral and community awareness raising…
- Trial name
- Triage-Plus (NCT01841541)
- Testing
- Referral of presumptive of TB cases by informal providers
- Where
- Sudan
- Volunteers
- 380 people
- Sponsor
- Liverpool School of Tropical Medicine
Malaria
Intravenous Artesunate and Malaria
Intravenous artesunate is egual to quinine in the treatment of severe malaria
- Trial name
- IVAS (NCT01805232)
- Testing
- artesunate, Quinine
- Where
- Sudan
- Volunteers
- 80 people
- Sponsor
- University of Khartoum
Caesarean
Prophylactic Ceftizoxime (Cefizox) for Elective Cesarean Delivery
Ceftizoxime (Cefizox) will reduce post Cesarean delivery febrile morbidity.
- Trial name
- NCT01347593
- Testing
- ceftizoxime
- Where
- Sudan
- Volunteers
- 220 people
- Sponsor
- University of Khartoum
Schistosomiasis
Schistosoma Haematobium Infections and Praziquantel
The purpose of this study is to evaluate the impact of praziquantel for the treatment of Schistosoma haematobium infection among schoolchildren in Al Salamania in Central Sudan.
- Trial name
- NCT01558336
- Testing
- praziquantel
- Where
- Sudan
- Volunteers
- 520 people
- Sponsor
- University of Khartoum
Vivax Malaria
Artemether/Lumefantrine and Vivax Malaria
The cure rate of artemether/lumefantrine in the treatment of vivax malaria.
- Trial name
- NCT01625871
- Testing
- tablets artemether/lumefantrine
- Where
- Sudan
- Volunteers
- 38 people
- Sponsor
- University of Khartoum
Malaria, Falciparum
Impact of Insecticide Resistance on Vector Control
The purpose of the study is to determine whether long lasting insecticidal nets and indoor residual insecticide spraying, alone or in combination, are effective for controlling insecticide resistant anopheles mosquitoes for…
- Trial name
- NCT01713517
- Testing
- Indoor residual insecticide spraying (IRS), Long Lasting Insecticidal Nets (LLIN)
- Where
- 3 sites in Sudan
- Volunteers
- 28,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Post Kala Azar Dermal Leishmaniasis
Safety and Immunogenicity of the LEISH-F2 + MPL-SE Vaccine With SSG for Patients With PKDL
A phase 1, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and immunogenicity of three injections of 10 µg LEISH-F2 + 25 µg MPL-SE given at 14-day intervals as an adjunct to standard…
- Trial name
- NCT00982774
- Testing
- LEISH-F2 + MPL-SE vaccine
- Where
- Sudan
- Volunteers
- 42 people
- Sponsor
- Access to Advanced Health Institute (AAHI)
Malaria
Dihydroartemisinin- Piperaquine Versus Artemether- Lumefantrine in the Treatment Uncomplicated Plasmodium Falciparum Malaria in Sudan
Dihydroartemisinin- Piperaquine is not inferior to artemether-lumefantrine
- Trial name
- NCT01075945
- Testing
- Dihydroartemisinin- piperaquine, artemether- lumefantrine
- Where
- Sudan
- Volunteers
- 140 people
- Sponsor
- University of Khartoum
Plasmodium Falciparum, Asymptomatic Parataemia
Antimalarial Treatments for Clearing Low Density P. Falciparum and Its Impact on Malaria Transmission
The malaria parasite Plasmodium falciparum remains at sub-patent level throughout the dry season in areas of seasonal malaria transmission.
- Conditions
- Plasmodium Falciparum, Asymptomatic Parataemia, Sub Patent Parasitaemia
- Trial name
- NCT00646126
- Testing
- Sulfadoxine / Pyrimethamine (SP) plus artesunate (AS)
- Where
- Sudan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tropical Medicine Research Institute
Falciparum Malaria, Antimalarials
The Impact of Artemether-Lumefantrine on Genes Associated With Antimalarial Resistance
The newly introduced antimalarial drug artemether-lumefantrine is currently recommended as second line antimalarial in Sudan. Recurrent infection after treatment with this drug has been associated with selection of certain genes…
- Trial name
- NCT00440752
- Where
- Sudan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tropical Medicine Research Institute
Plasmodium Falciparum Malaria
Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria
The purpose of this open randomised multi-centre clinical trial is to test the hypothesis that three pills of the fixed dose combination artesunate/sulfamethoxypyrazine/pyrimethamine, administered over 24 hours is not inferior in…
- Trial name
- NCT00484900
- Testing
- Co-Arinate FDC, Coartem
- Where
- 4 sites in Cameroon, Mali and 2 more
- Volunteers
- 1,390 people
- Sponsor
- Dafra Pharma
Plasmodium Infections
Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan
In areas of seasonal malaria transmission, treatment of carriers of malaria parasites, whose parasitaemia persists at very low levels throughout the dry season, could be a useful strategy for malaria control in areas with a short…
- Trial name
- NCT00330902
- Testing
- sulfadoxine-pyrimethamine (SP) plus artesunate (AS), primaquine (PQ) plus SP+AS
- Where
- Sudan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine