Clinical trials: in Syria
Bruxism, Anxiety
Bruxism, Anxiety, and Periodontal Status Among Dental Students
This observational cross-sectional study aims to evaluate the relationship between bruxism, anxiety, and periodontal status among fourth- and fifth-year dental students at Al-Hawash Private University.
- Trial name
- NCT07579416
- Where
- Syria
- Volunteers
- 100 people
- Sponsor
- Al-Hawash Private University
Periodontal Disease, Periodontal Diseases
Candida Albicans in Syrian Patients With Periodontitis
Periodontitis is a significant oral health issue characterized by inflammation and destruction of the supporting structures of the teeth.
- Conditions
- Periodontal Disease, Periodontal Diseases, Periodontitis
- Trial name
- NCT07574827
- Testing
- Periodontal Assessment and Sample Collection from Subgingival Pockets
- Where
- Syria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Hawash Private University
Cataract, Inflamation
A Study Comparing Sub-Tenon Steroid Injection Versus Eye Drops for Reducing Postoperative Inflammation After Cataract Surgery
After cataract surgery, postoperative inflammation is commonly treated with corticosteroid eye drops such as prednisolone acetate 1%. However, frequent dosing may reduce patient compliance.
- Conditions
- Cataract, Inflamation, Phacoemulsification
- Trial name
- NCT07567118
- Testing
- Triamcinolone acetonide injection, prednisolone acetate 1%
- Where
- Syria
- Volunteers
- 72 people
- Sponsor
- Damascus University
Primary Frontal Hyperhidrosis
Botulinum Toxin Type A for Frontal Hyperhidrosis
Frontal hyperhidrosis is a form of primary focal hyperhidrosis that significantly impairs patients' quality of life due to excessive visible sweating in the forehead region.
- Trial name
- NCT07561580
- Testing
- Botulinum Toxin Type A
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Latakia University
Gummy Smile
Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery
A gummy smile can negatively affect a patient's self-confidence and satisfaction with their appearance, leading many individuals to seek effective esthetic solutions.
- Trial name
- NCT07532161
- Testing
- Liquid Platelet-Rich Fibrin group, low-level laser group
- Where
- Syria
- Volunteers
- 22 people
- Sponsor
- Damascus University
Orthodontic Appliance Complication
Effect of Local Subperiosteal Zoledronic Acid Injection on the Survival of Orthodontic Miniscrews
Background: Orthodontic miniscrews are widely used as temporary anchorage devices; however, failure remains a clinical concern. Bisphosphonates may enhance bone stability, but evidence on their local application is limited.
- Trial name
- NCT07546058
- Testing
- Zoledronic Acid, Normal saline (0.9% sodium chloride)
- Where
- Syria
- Volunteers
- 68 people
- Sponsor
- Latakia University
Hyperbilirubinemia, Neonatal Indirect
The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect Hyperbilirubinemia
This is a prospective, open-label, randomized controlled trial conducted at Lattakia University Hospital (Tishreen University), aiming to evaluate the efficacy of Ursodeoxycholic Acid (UDCA) as an adjuvant to triple phototherapy…
- Trial name
- UDCA-Neo (NCT07110987)
- Testing
- Phototherapy, ursodeoxycholic acid (UDCA)
- Where
- Syria
- Volunteers
- 70 people
- Sponsor
- Tishreen University Hospital
Myasthenic Crisis, Myasthenia Gravis (MG)
Efficacy of IVIG Versus PLEX in Myasthenic Crisis in Syria.
This study compares the clinical effectiveness of Intravenous Immunoglobulin (IVIG) versus Plasma Exchange (PLEX) in patients experiencing a myasthenic crisis.
- Trial name
- NCT07532707
- Testing
- IVIG (Intravenous Immunoglobulin), Plasma exchange (PE)
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Gingival Pigmentation
Nano Silver Effect in Rapid Wound Healing
Silver compounds have demonstrated a positive effect in most medical fields, including periodontal therapy, particularly in their nano-formulations.
- Trial name
- NCT07521176
- Testing
- Nano Silver Dressing, Non eugenol zinc oxide Dressing
- Where
- Syria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Damascus University
Coronary Artery Disease, Hypertension
Association Between Some Polymorphisms in Apelin/ Apelin Receptor Genes and Coronary Artery Disease in Syrian Patients
The apelin-APJ signaling pathway has emerged as an important novel mediator of cardiovascular control and blood pressure homeostasis.
- Trial name
- NCT05562687
- Where
- Syria
- Volunteers
- 223 people
- Sponsor
- Damascus University
Internal Mammary Artery Syndrome, Vasodilation
Effect of Topically-applied Milrinone or Nitroglycerin on Internal Mammary Artery Free Flow
Forty-six consecutive patients undergoing elective primary coronary artery bypass grafting were enrolled. After the left IMA was harvested, free flow was measured under controlled hemodynamic conditions before any intervention…
- Trial name
- NCT06301880
- Testing
- The topical application of a vasodilator on the LIMA graft
- Where
- Syria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Damascus University
Dental Anxiety, Dental Pain
Clinical Outcomes of Mandibular Primary Molar Extraction Using Physics Forceps in Children
Tooth extraction is a common procedure and often associated with pain, fear, and discomfort especially in pediatric patients, which may lead to a negative attitude toward the dental.
- Conditions
- Dental Anxiety, Dental Pain, Dental Extraction, Primary Molar Tooth
- Trial name
- NCT07366788
- Testing
- ARM 1 Physics forceps (40 Participant), ARM 2 conventional forceps (40 Participant)
- Where
- Syria
- Volunteers
- 80 people
- Sponsor
- Damascus University
Myocardial Injury, Cardiac Surgery
Comparison of Changes in Intra-myocardial Amino Acids During Use of Calafiore and Modified Del Nido Cardioplegia
The aim of the present study was to investigate intra-operative changes in markers of myocardial injury and myocardial intracellular amino acids during ischemia and reperfusion, comparing two methods of myocardial protection…
- Conditions
- Myocardial Injury, Cardiac Surgery, Myocardial Protection
- Trial name
- NCT06287372
- Testing
- Cardioplegic solution
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Distal Radius Fracture, Vitamine c
Vitamin c Supplementation in the Prevention of CRPS Following Distal Radius Fractures
Complex Regional Pain Syndrome type 1 is a pain syndrome that develops after a trauma, surgery, or idiopathically. The incidence after distal radius varies significantly in the literature.
- Conditions
- Distal Radius Fracture, Vitamine c, Prophylaxis
- Trial name
- NCT05842395
- Testing
- Vitamin C
- Where
- Syria
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Damascus University
Arthritis Knee, Pain
The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA
This interventional study aims to compare the effectiveness of local multimodal drug periarticular injection in TKA patients with the standard pain control regime that includes opioids, NSAIDs, and other analgesics.
- Conditions
- Arthritis Knee, Pain, Arthroplasty Complications
- Trial name
- NCT06112548
- Testing
- primary unilateral TKA, Bupivacain, ketorolac
- Where
- Syria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damascus University
Radiation-induced Oral Mucositis
Benzydamine for Radiation-Induced Oral Mucositis in Patients Receiving High-Dose Radiotherapy
This single-center, open-label, randomized clinical trial evaluates the effect of 0.15% benzydamine hydrochloride (Difflam) oral spray on the severity of radiation-induced oral mucositis in patients with head and neck cancer…
- Trial name
- NCT07467759
- Testing
- benzydamine hydrochloride, saline mouth rinse
- Where
- Syria
- Volunteers
- 35 people
- Sponsor
- Latakia University
Malocclusion; Displaced Teeth
Can Magnification Loupes Make the Bracket Bonding Procedure Faster and More Comfortable?
This study aims to evaluate whether using 3.5x dental magnification loupes improves the speed and patient comfort of the orthodontic bracket placement procedure in patients with crowded dentition, a condition that can make the…
- Trial name
- NCT07474389
- Testing
- Loupes-based bonding, Traditional bonding
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Malocclusion, Angle Class II, Division 1
Evaluating Laser and Piezocision vs. Piezocision Alone on Root Resorption and Gingival Health During Tooth Retraction
This trial aims to determine whether using a special laser (low-level laser therapy, or LLLT) in combination with a minor surgical procedure (piezocision) can safely accelerate orthodontic treatment.
- Trial name
- NCT07442825
- Testing
- Flapless Corticotomy (Piezocision), Level Laser Therapy (LLLT), Traditional treatment
- Where
- Syria
- Volunteers
- 66 people
- Sponsor
- Damascus University
This Study Aims to Evaluate the Effectiveness of the INJEX Device in Administering Local Anesthesia
Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia.
Local anesthesia is a common and essential procedure for the majority of dental treatments. The most frequently used method of administration is needle injection.
- Trial name
- NCT07426523
- Testing
- INJEX 30, Traditional syringe
- Where
- Syria
- Volunteers
- 52 people
- Sponsor
- Damascus University
Evaluation of Deep Plan Intervention in the Submental Region for Double Chin Management
Evaluation of the Effectiveness of Deep Intervention in the Submental Region in Context of Managing of Double Chin (Clinical Study)
what problem is this study investigating some people suffer from what is called a double chin or the accumulation of fat and sagging skin under the chin which may affect the profile and cause dissatisfaction what is the main…
- Trial name
- NCT07391176
- Testing
- Evaluation of platysma muscle partial resection with midline plication for double chin correction
- Where
- Syria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Latakia University