Clinical trials: in The Gambia
Malaria
Lapdap and Coartemether for Uncomplicated Malaria
Lapdap (chlorproguanil-dapsone) is an affordable and effective drug, but patients with glucose-6-phosphate dehydrogenase (G6PD) A- deficiency are more susceptible to the haemolytic effects of the dapsone component of Lapdap…
- Trial name
- NCT00118794
- Testing
- Chlorproguanil-dapsone (Lapdap), Lumefantrine-artemether (Coartemether )
- Where
- The Gambia
- Volunteers
- 1,200 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Malaria
Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children
The purpose of this trial is to compare the effectiveness of three combination treatments for uncomplicated malaria when given in operational settings, without supervision of doses other than the first dose.
- Trial name
- NCT00118807
- Testing
- Amodiaquine plus artesunate (AQ/AS), Sulfadoxine-pyrimethamine plus chloroquine (SP/CQ), Sulfadoxine-pyrimethamine plus amodiaquine (SP/AQ)
- Where
- The Gambia
- Volunteers
- 1,800 people
- Sponsor
- London School of Hygiene and Tropical Medicine