Clinical trials: in Uzbekistan
Multi-drug Resistant Tuberculosis, Extensively Drug-Resistant Tuberculosis
Economic Evaluation of New MDR TB Regimens
The current treatment regimen for MDR-TB has poor outcomes and costs of treating MDR-TB are greater than treating drug susceptible TB, both in terms of health service and patient-incurred costs.
- Conditions
- Multi-drug Resistant Tuberculosis, Extensively Drug-Resistant Tuberculosis, Pulmonary Tuberculoses
- Trial name
- PRACTECAL-EE (NCT04207112)
- Testing
- Bedaquiline, Pretomanid, Moxifloxacin
- Where
- 7 sites in Belarus, South Africa and 1 more
- Volunteers
- 73 people
- Sponsor
- Medecins Sans Frontieres, Netherlands
Obesity
Clinical Feasibility Study of the BariTon™ System in Obese Patients
Safety evaluation of BariaTek Medical gastric restriction and biliodigestive diversion device.
- Trial name
- NCT06317129
- Testing
- Endoscopic gastric restriction and biliodigestive diversion
- Where
- Uzbekistan
- Volunteers
- 10 people
- Sponsor
- BariaTek Medical
Incisional Hernia
Impact Evaluation of Incisional Hernia on Muscular and Postural Function
Purpose of study is to assess perioperative functional parameters of the anterior abdominal wall muscles and postural control status in patients with large and giant incisional hernias in a controlled diagnostic study.
- Trial name
- IHMPF-1 (NCT05990647)
- Testing
- Dynamometric tension assessment, Postural balance, Assessment of the hernia defect size
- Where
- Uzbekistan
- Volunteers
- 95 people
- Sponsor
- Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov
COPD Exacerbation Acute, Ascaris Lumbricoides Infection
Impact of A. Lumbricoides on Pulmonary Aspergillosis Development
The prevalence of ascariasis in COPD patients with and without concomitant pulmonary aspergillosis and in controls will be determined.
- Conditions
- COPD Exacerbation Acute, Ascaris Lumbricoides Infection, Chronic Pulmonary Aspergillosis
- Trial name
- NCT05783544
- Testing
- Interleukin-1B, Interleukin-4, Interleukin-6
- Where
- Uzbekistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
COVID-19 Respiratory Infection
Studying the Efficiency of the Natural Preparation Rutan in Children in the Treatment of COVID-19, ARVI
Clinical research includes Determination of efficacy and acceptability of the local medicine "Rutan tablets 0,025" in children and teenagers 6-18 years old with COVID-19 and/or acute respiratory viral infections.
- Trial name
- NCT05862883
- Testing
- Rutan 25 mg, Control group
- Where
- Uzbekistan
- Volunteers
- 301 people
- Sponsor
- Research Institute of Virology, Ministry of Health of the Republic of Uzbekistan
Patients With COVID-19
Conducting Clinical Trials of the Medicine "Rutan Tablets 0.1g" No. 10 in the Complex Therapy of COVID-19
The purpose of this clinical trial is to evaluate the efficacy and safety of the registered drug Rutan 0.1 against SARS-CoV-2 in patients with COVID-19.
- Trial name
- NCT05859919
- Testing
- The drug "Rutan 0.1"., Basic treatment
- Where
- Uzbekistan
- Volunteers
- 57 people
- Sponsor
- Research Institute of Virology, Ministry of Health of the Republic of Uzbekistan
Primary Headache Disorder
Gender Differences and Features of the Clinical Course of Primary Headaches
The pathophysiological mechanisms that underlie primary headache disorders, such as migraine and cluster headache (CH), are complex and not yet fully clarified.
- Trial name
- NCT05760625
- Testing
- analysis BDNF
- Where
- Uzbekistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tashkent Medical Academy
Moderate to Severe COVID-19
Efficacy and Safety of JT001 (VV116) Compared With Favipiravir
The purpose of this study is to evaluate the efficacy and safety of JT001 (VV116) for the Treatment of Coronavirus Disease 2019 (COVID-19) in participants with moderate to severe COVID-19.
- Trial name
- NCT05279235
- Testing
- JT001, Favipiravir
- Where
- 2 sites in China, Uzbekistan
- Volunteers
- 290 people
- Sponsor
- Shanghai Vinnerna Biosciences Co., Ltd.
COVID-19
A Trial Evaluate the Immunogenicity and Safety of Recombinant COVID-19 Omicron-Delta Variant Vaccine (CHO Cell)
The study was designed as a randomized, blind and controlled trial. A total of 300 patients aged 18 and above who were immunized with recombinant novel coronavirus protein vaccine (CHO cell) for more than 4 months (60 patients…
- Trial name
- NCT05616754
- Testing
- Omicron-Delta Recombinant Novel Coronavirus Protein Vaccine (CHO cells), Recombinant Novel Coronavirus Protein Vaccine (CHO cells)
- Where
- Uzbekistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Prevention of COVID-19, Safety and Efficacy
A Phase III Clinical Trial to Determine the Safety and Efficacy of ZF2001 for Prevention of COVID-19
A randomized, double-blind, placebo-controlled international multicenter clinical trial design will be adopted. A total of 29,000 subjects aged 18 years and above are planned to be recruited, including 750 subjects aged 18-59…
- Trial name
- NCT04646590
- Testing
- Recombinant new coronavirus vaccine (CHO cell) group
- Where
- 18 sites in China, Ecuador and 3 more
- Volunteers
- 28,904 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Patients With Kimmerle's Anomaly
Radial Visualization of the Foramen Arcuale Atlantis
Hemodynamics in the craniovertebral zone is often disturbed under the influence of a spondylogenic factor A complication of such changes can be from a slight decrease in cerebral circulation to ischemic changes in the vascular…
- Trial name
- NCT05160259
- Testing
- Radial visualization of the foramen arcuale atlantis
- Where
- Uzbekistan
- Volunteers
- 60 people
- Sponsor
- Samarkand State Medical Institute
Coronary Disease, Aortic Valve Stenosis
Quantitative Measurement of Myocardial Perfusion by Cardiac CT in Patients
It is a common understanding that patients with coronary heart disease are suffering, among others, from reduced myocardial perfusion.
- Trial name
- CCT/MPERF (NCT02361996)
- Where
- 3 sites in Austria, Russia and 1 more
- Volunteers
- 690 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Acute Bronchiolitis
Evaluation of the Effectiveness of Montelukast in Children With Recurrent Obstructive Bronchitis
The aim of the study was to evaluate the effectiveness of montelukast sodium in the treatment and prevention of recurrent obstructive bronchitis in children.
- Trial name
- NCT04613180
- Testing
- Montelukast Sodium
- Where
- Uzbekistan
- Volunteers
- 100 people
- Sponsor
- Samarkand State Medical Institute
Metabolic Syndrome
Determination of Risk Factors for the Development of Obesity and Hypertension in Children According to Perinatal Programming of Metabolism
to determine the risk factors for developing obesity in children with exogenous-constitutional obesity and arterial hypertension, according to the theories of early programming of metabolism
- Trial name
- NCT04611412
- Testing
- Risk Factors
- Where
- Uzbekistan
- Volunteers
- 55 people
- Sponsor
- Samarkand State Medical Institute
Obstructive Uropathy
Ultrasonic Visualization of Obstructive Uropathies in Children
The purpose of this study was to develop proposals and recommendations for improving the safety of urological examination of children with obstructive uropathy by using Doppler ultrasound.
- Trial name
- NCT04605835
- Testing
- ULTRASONIC VISUALIZATION OF OBSTRUCTIVE UROPATHIES IN CHILDREN.
- Where
- Uzbekistan
- Volunteers
- 655 people
- Sponsor
- Samarkand State Medical Institute
Coronary Heart Disease
Unstable Angina Pectoris in Comorbidity With Anxiety-depressive Syndrome
Introduction: Today it is necessary to emphasize that coronary heart disease is often associated with anxiety disorders. Research over the years has shown several and sometimes surprising links between coronary heart disease and…
- Trial name
- NCT04599621
- Testing
- Collection of blood samples to determine the level of certain cytokines (TNF-α, IL-1β, IL-4 and IL-10),Collection of blood samples to determine the level of uric acid
- Where
- Uzbekistan
- Volunteers
- 3 people
- Sponsor
- Samarkand State Medical Institute
Viral Intestinal Infection
Clinical Trial of Efficacy and Safety of Ergoferon in the Treatment of Viral Intestinal Infections in Children
The purpose of this study is to obtain additional data on efficacy and safety of Ergoferon in the treatment of viral intestinal infections in inpatient children.
- Trial name
- NCT03039699
- Testing
- Ergoferon
- Where
- 13 sites in Russia, Uzbekistan
- Volunteers
- 259 people
- Sponsor
- Materia Medica Holding
Kimmerle's Anomaly
Verification of Kimmerle's Anomaly by X-ray Methods of Research
Kimmerle's anomaly is a bony bridge over the posterior arch of the first cervical vertebra that forms a bony ring. The vertebral artery passes through the opening.
- Trial name
- NCT04562259
- Testing
- Verification of Kimmerle's anomaly by x-ray methods of research
- Where
- Uzbekistan
- Volunteers
- 100 people
- Sponsor
- Samarkand State Medical Institute
Preventive Medicine
Clinical Trial of Anaferon for Children Efficacy in Prevention of Influenza and Other ARVI
The objective of this study is to obtain additional data on the efficacy and safety of 12-week course of therapy with Anaferon for children for prevention of influenza and other acute respiratory viral infections in children…
- Trial name
- NCT03301155
- Testing
- Anaferon for children
- Where
- 33 sites in Russia, Uzbekistan
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- Materia Medica Holding
Sepsis, Intoxication; Septic
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis.
This study evaluates the efficacy and safety of Rheosorbilact®, solution for infusion ("Yuria-Pharm" LLC), in comparison with Ringer's Lactate, solution for infusion, in a complex therapy of sepsis.
- Trial name
- NCT03764085
- Testing
- Rheosorbilact®, Ringer lactate
- Where
- 13 sites in Georgia, Kazakhstan and 3 more
- Volunteers
- 180 people
- Sponsor
- Yuria-Pharm