Clinical trials: Amlodipine
Healthy
Compare the Pharmacokinetics of TAH(80/10/12.5) Tablet in Comparison to the Co-administration of Telmisartan, Amlodipine and Hydrochlorothiazide in Healthy Male Volunteers
randomized, open-label, single dose, replicate crossover clinical trial to compare the pharmacokinetics of TAH(80/10/12.5) tablet in comparison to the co-administration of telmisartan, amlodipine and hydrochlorothiazide in…
- Trial name
- NCT03032315
- Testing
- TAH Tablet (Telmisartan80/Amlodipine besylate10/Hydrochlorothiazide12.5), TWYNSTA(Telmisartan+Amlodipine besylate), Hydrochlorothiazide
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Healthy Male Subjects
Clinical Trial to Assess the Pharmacokinetic Characteristics of Lodivixx Tab. 5/160mg in Healthy Male Subjects (N=27)
To assess the pharmacokinetic characteristics of valsartan and S-amlodipine after single oral administration of Exforge tab. 10/160mg, a combination formulation of valsartan and amlodipine as reference drug and Lodivixx tab.
- Trial name
- NCT03648333
- Testing
- Exforge tab. 10/160mg, Lodivixx tab. 5/160mg
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Hypertension
Study of Co-administration of Olmesartan Medoxomil Plus Amlodipine in Patients With Mild to Severe Hypertension
This study assesses the efficacy and safety of co-administration of olmesartan medoxomil plus amlodipine in mild to severe hypertensive patients older than 18 years of age
- Trial name
- NCT00185133
- Testing
- Olmesartan medoxomil, Amlodipine
- Where
- 139 sites in United States
- Volunteers
- 1,900 people
- Sponsor
- Daiichi Sankyo
Hypertension
Aliskiren Study of Safety and Efficacy in Senior Hypertensives
This study is designed to compare the blood pressure lowering efficacy of aliskiren, a combination of aliskiren plus amlodipine, and ramipril in elderly patients with mild to moderate hypertension.
- Trial name
- ASSESS (NCT01922141)
- Testing
- Aliskiren, Amlodipine, Ramipril
- Sponsor
- Novartis Pharmaceuticals
Hypertension
CKD-828 (40/5mg) Pharmacokinetic Study
The purpose of this study is to evaluate the pharmacokinetic characteristics of CKD-828 (Fixed Dose Combination Tablet; Telmisartan and S-Amlodipine) in healthy volunteer.
- Trial name
- NCT01340131
- Testing
- CKD-828, Combination Therapy
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension
CKD-330 Drug-Drug Interaction Study (Candesartan)
The purpose of this study is to evaluate a pharmacokinetic drug interaction and safety of Candesartan between free combination of Candesartan and Amlodipine and Candesartan monotherapy.
- Trial name
- CKD-330(C) (NCT02064621)
- Testing
- Candesartan 32mg, Candesartan 32mg/Amlodipine 10mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Essential Hypertension
Efficacy and Safety of TAH Combination in Comparison With Telmisartan/Amlodipine Combination for Essential Hypertension Patients
Randomized, Double-Blind, Multi-Center, Phase 3 Trial to Evaluate the Efficacy and Safety of Telmisartan/Amlodipine/Hydrochlorothiazide Combination in Comparison with Telmisartan/Amlodipine Combination for Essential Hypertension…
- Trial name
- NCT02738632
- Testing
- Telmisartan/Amlodipine+Hydrochlorothiazide, Telmisartan/Amlodipine
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Hypertension
Blood Pressure Lowering of Aliskiren Hydrochlorothiazide (HCTZ) Versus Amlodipine in Stage 2 Hypertension in African Americans
The purpose of the study is to evaluate the efficacy and safety of a fixed dose combination of aliskiren HCTZ versus amlodipine in African American patients with Stage 2 hypertension.
- Trial name
- ATLAAST (NCT00739596)
- Testing
- Aliskiren Hydrochlorothiazide (HCTZ): 8 weeks, Amlodipine: 8 weeks
- Where
- United States
- Volunteers
- 332 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension
Telmisartan Fixed Dose Combination vs Amlodipine in Hypertensive Patients With Type 2 Diabetes Mellitus
To demonstrate that the fixed dose combination of telmisartan and amlodipine is more effective in lowering blood pressure.
- Trial name
- NCT00877929
- Testing
- Telmisartan 80, Amlodipine 10
- Where
- 65 sites in United States, Argentina and 7 more
- Volunteers
- 706 people
- Sponsor
- Boehringer Ingelheim
Hypertension, Primary Hypercholesterolaemia
To Evaluate the Efficacy and Safety of Co-administrated HODO-2224-1 and HODO-2224-2 in Patients With Essential Hypertension and Primary Hypercholesterolemia
A Multicenter, Randomized, Double-blind, Active-controlled, Parallel group, Phase 3 trial to Evaluate the Efficacy and Safety of Co-administrated HODO-2224-1 and HODO-2224-2 in Patients with Essential Hypertension and Primary…
- Trial name
- HODO-2224 (NCT06646354)
- Testing
- Ezetimibe/Rosuvastatin/Candesartan/Amlodipine, Candesartan/Amlodipine, Candesartan/Rosuvastatin/Ezetimibe
- Where
- South Korea
- Volunteers
- 125 people
- Sponsor
- Hyundai Pharm
Hypertension
A Study Comparing the Response of Patients With Hypertension to Amlodipine or Amlodipine Plus Benazepril.
Comparison of the safety and efficacy of the combination of amlodipine/Benazepril to amlodipine monotherapy in patients with non-essential hypertension, not controlled on amlodipine alone.
- Trial name
- NCT00171366
- Testing
- amlodipine/benazepril
- Where
- United States
- Volunteers
- 1,422 people
- Sponsor
- Novartis
Hypertension
Vascular Improvement With Olmesartan Medoxomil Study
The purpose of this study is to compare in patients with primary hypertension, the non-blood pressure lowering effects of one-year therapy with olmesartan medoxomil vs.
- Trial name
- VIOS (NCT00772499)
- Testing
- olmesartan medoxomil + hydrochlorothiazide + amlodipine + hydralazine if necessary to control blood pressure, atenolol+ hydrochlorothiazide + amlodipine + hydralazine if necessary to control blood pressure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Daiichi Sankyo
Hypertension (HTN), Hypertension
A Study to Evaluate the Effectiveness and Safety of S-amlodipine-based Monotherapy and Combination Therapy
This study aims to evaluate the effectiveness, safety, and clinical utility as a treatment strategy of the s-amlodipine-based monotherapy, dual combination, and triple combination in patients with hypertension across various…
- Conditions
- Hypertension (HTN), Hypertension, Essential (Primary) Hypertension
- Trial name
- STRIKE (NCT07907822)
- Volunteers
- 4,528 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Hypertension, Hyperlipidemia
Comparing Amlodipine/Atorvastatin Co-Administration To Amlodipine Alone In Patients With Hypertension And Dyslipidemia
To evaluate efficacy of the dual therapy of atorvastatin + amlodipine vs. amlodipine alone .
- Trial name
- NCT00174330
- Testing
- atorvastatin, amlodipine
- Where
- 15 sites in China
- Volunteers
- 330 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hypertension
A Study to Evaluate the Effect of LCZ696 on Aortic Stiffness in Subjects With Hypertension
This was the first evaluation of the effects of LCZ696 on local and regional measures of aortic stiffness in subjects with mild to moderate hypertension and widened pulse pressure.
- Trial name
- NCT01870739
- Testing
- sacubitril/valsartan (LCZ696), olmesartan, Amlodipine (Optional)
- Where
- 4 sites in Germany, Switzerland and 1 more
- Volunteers
- 115 people
- Sponsor
- Novartis Pharmaceuticals
Healthy
Bioequivalence Study of 10 mg Amlodipine Besylate/ 20 mg Benazepril Hydrochloride Capsules of Dr.Reddys Laboratories Limited Under Fasting Conditions
The objective of this study was to compare the single-dose relative bioavailability of Dr. Reddy's Laboratories, Ltd. and Lotrel®) 10 mg amlodipine besylate/20 mg benazepril hydrochloride capsules, under fasting conditions.
- Trial name
- NCT01155895
- Testing
- Amlodipine Besylate / Benazepril Hydrochloride
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Myocardial Ischemia
Amlodipine vs Nitrates Study in Patients With Chronic Stable Angina
The objective of study is to compare the anti-ischemic efficacy and safety profiles of once daily amlodipine or isosorbide-5-mononitrate in the treatment of stable asymptomatic and symptomatic myocardial ischemia
- Trial name
- ANISSA (NCT00143195)
- Testing
- Amlodipine, iso- 5 - mononitrate, Blood tests
- Where
- 12 sites in Greece
- Volunteers
- 200 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hypertension
Effectiveness of a Valsartan Based Versus an Amlodipine Based Treatment Strategy in naïve Patients With Stage 1 or Stage 2 Hypertension or in Patients Uncontrolled on Current Monotherapy
The population for this current study will include stage 1 and stage 2 hypertensive patients who are newly diagnosed or didn't have treatment during the last 3 months and patients who are currently treated but uncontrolled on…
- Trial name
- NCT00304226
- Testing
- valsartan, amlodipine
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 1,288 people, healthy volunteers welcome
- Sponsor
- Novartis
Healthy
Relative Bioavailability of Telmisartan/Amlodipine Fixed-dose Combination Compared to Its Mono-components in Healthy Male Volunteers
Study to investigate the relative bioavailability of fixed-dose combination tablet vs. mono-components of telmisartan and amlodipine
- Trial name
- NCT02259803
- Testing
- Telmisartan/amlodipine fixed-dose combination (FDC) tablet, Telmisartan, Amlodipine
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Hypertension, Hyperlipidemia
Clinical Trial of Temisartan/Amlodipine & Rosuvastatin in Subjects With Hypertension and Hyperlipidemia
Randomized, double-blind, active-controlled, multicenter phase 3 trial to evaluate efficacy and safety of co-administrated temisartan/amlodipine and rosuvastatin in subjects with hypertension and hyperlipidemia.
- Trial name
- NCT03067688
- Testing
- Temisartan+Amlodipine+Rosuvastatin (Combination drug), Temisartan+Amlodipine, Temisartan+Rosuvastatin
- Where
- South Korea
- Volunteers
- 202 people
- Sponsor
- Yuhan Corporation