Clinical trials: Amlodipine
Essential Hypertension
Amlodipine VaLsartan Efficacy in Hypertensive Patients.A Real World Trial
To determine the efficacy of valsartan/amlodipine 80/5 mg once daily dose is reducing mean sitting systolic blood pressure (MSSBP) and mean sitting diastolic blood pressure (MSDBP) after 8 weeks of therapy.
- Trial name
- ALERT (NCT03371797)
- Testing
- Valsartan, Amlodipine -
- Where
- Pakistan
- Volunteers
- 800 people
- Sponsor
- PharmEvo Pvt Ltd
Hypertension
Effectiveness and Safety of Sequential Triple Combination Therapy (Amlodipine/Losartan/Chlorthalidone) in Korean Patients With Hypertension
A multicenter, prospective, non-interventional, observational study to evaluate effectiveness and safety of sequential triple combination therapy (amlodipine/losartan/chlorthalidone) in Korean patients with hypertension
- Trial name
- AMPR-OS-2503 (NCT07784296)
- Testing
- AMOPREL TAB 1.67/16.67/4.17mg
- Where
- South Korea
- Volunteers
- 3,500 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Hypertension, High Blood Pressure
To Demonstrate Non-inferiority of Combination of 5 mg Amlodipine/ 80 mg Valsartan to 160 mg Valsartan Alone
The purpose of the study was to assess efficacy and safety of fixed dose combination of 5 mg amlodipine/80 mg valsartan compared to 160 mg valsartan monotherapy in lowering blood pressure in Taiwanese patients.
- Trial name
- NCT01070043
- Testing
- Amlodipine 5mg/Valsartan 80 mg, Valsartan
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Novartis
Essential Hypertension
A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Candesartan Cilexetil Monotherapy
Compare the safety and efficacy of amlodipine besylate and candesartan cilexetil combination therapy on patients of essential hypertension who are not properly controlled by candesartan cilexetil monotherapy.
- Trial name
- NCT02368652
- Testing
- Candesartan cilexetil 16mg, Amlodipine 10mg, Candesartan cilexetil 16mg
- Where
- 19 sites in South Korea
- Volunteers
- 181 people
- Sponsor
- HK inno.N Corporation
Hypertension, Essential Hypertension
Evaluate the Efficacy and Safety of SPC1001 and Monotherapy in Patients With Essential Hypertension
This study purpose is to determine the appropriate combination drug dose by comparing safety and efficacy with placebo, candesartan, and amlodipine monotherapy after 8 weeks of administration of SPC1001 to patients with essential…
- Trial name
- SP-CAP-002 (NCT06212648)
- Testing
- SPC1001 High, SPC1001 Mid1, SPC1001 Mid2
- Where
- South Korea
- Volunteers
- 253 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Essential Hypertension
A Phase 2 Dose Selection Trial of Candesartan Cilexetil and Amlodipine Besylate to Treat Essential Hypertension
The purpose of this study is to explore the optimal dose of fixed-dose combination of candesartan cilexetil and amlodipine besylate by examining the safety and efficacy of the combination therapy compared to each of the…
- Trial name
- NCT02059616
- Testing
- Amlodipine 5mg, Amlodipine 10mg, Candesartan Cilexetil 8mg
- Where
- 20 sites in South Korea
- Volunteers
- 384 people
- Sponsor
- HK inno.N Corporation
Hypertension
CKD-828(80/2.5mg) Pharmacokinetic Study
The purpose of this study is to evaluate the pharmacokinetic characteristics of CKD-828(Fixed Dose Combination Tablet; Telmisartan and S-Amlodipine) in healthy volunteer.
- Trial name
- NCT01246193
- Testing
- CKD-828(FDC), Combination Therapy
- Where
- South Korea
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Type 2 Diabetes Mellitus
Drug-drug Interaction Study(CKD-501, Amlodipine)
The purpose of this study is to assess the pharmacokinetic drug interaction between CKD-501 and amlodipine after oral administration in healthy male volunteers.
- Trial name
- NCT01341392
- Testing
- CKD-501, amlodiopine, CKD-501 amlodipine
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension
A Clinical Trial to Evaluate the Safety and Pharmacokinetics of AJU-C52L in Healthy Volunteers
To evaluate the safety and pharmacokinetic characteristics of AJU-C52L in healthy adults
- Trial name
- NCT05077475
- Testing
- C52R1H Tab. and C52R2 Tab., AJU-C52L
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Hypertension
Safety and Pharmacokinetics Study of amlodipine10mg and candesartan32mg
Clinical trial to evalate the pharmacokinetic interactions and safety between single dose of amlodipine10mg and candesartan32mg and combiation dose amlodipine10mg with candesartan32mg in healthy male volunteers.
- Trial name
- NCT01806311
- Testing
- Candesartan32mg, Amlodipine10mg
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- HanAll BioPharma Co., Ltd.
Hypertension
Candesartan Cilexetil/Amlodipine Besilate Combination Tablets LD, HD Special Drug Use Surveillance "Hypertension: Long-Term Use"
The purpose of this survey is to investigate the safety and efficacy of long-term use of candesartan cilexetil/amlodipine besilate combination tablets (Unisia Combination Tablets) low dose (LD), high dose (HD) in participants…
- Trial name
- NCT02068495
- Testing
- Candesartan cilexetil/Amlodipine besilate
- Volunteers
- 3,409 people
- Sponsor
- Takeda
Healthy
Clinical Bioequivalence Study on Two Amlodipine Tablet 10mg Formulations
The purpose of the study is to compare the bioavailability of a generic product of amlodipine with that of a reference product when administered to healthy volunteers under fasting conditions.
- Trial name
- NCT02707913
- Testing
- BF-Amlodipine Tablet 10mg, Norvasc Tablet 10mg
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Bright Future Pharmaceuticals Factory O/B Bright Future Pharmaceutical Laboratories Limited
Adherence to Medication Regime, Hypertensive Disease
Study for the Recording of Adherence to Treatment With Perindopril/Indapamide/Amlodipine Fixed Dose Combination
The main objective of this study is to record, in routine clinical practice, patients' adherence to treatment with Perindopril/Indapamide/Amlodipine fixed dose combination, during 4 months treatment.
- Trial name
- CONTROL-3 (NCT02655029)
- Testing
- Perindopril/Indapamide/Amlodipine fixed dose combination
- Where
- Greece
- Volunteers
- 2,285 people
- Sponsor
- Servier Hellas Pharmaceuticals Ltd.
Hypertension
Bioequivalence Study (Candesartan 16 mg and Amlodipine 5 mg) - B
The purpose of this study is to compare the safety and pharmacokinetics of CKD-330 (fixed-dose combination of Candesartan 16 mg and Amlodipine 5 mg) with coadministration of the two separate drugs in healthy male volunteers.
- Trial name
- NCT02811731
- Testing
- CKD-330 16/5mg - B, Candesartan 16mg and Amlodipine 5mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Healthy
Amlodipine-Benazepril 10mg-20mg Capsules in Healthy Subjects Under Fed Conditions
The objective of this study is to compare the rate and extent of absorption if amlodipine-benzazepril 10 mg-20 mg capsules (test) versus Lotrel® (reference),administered as 1 x 10 mg- 20 mg capsule under fed conditions.
- Trial name
- NCT00835367
- Testing
- Amlodipine-benazepril 10 mg-20 mg capsules, Lotrel® 10 mg-20 mg capsule
- Where
- 2 sites in Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Hypertension
Efficacy and Safety of the Combination of Valsartan Plus Amlodipine in Hypertensive Patients Not Adequately Responding to the Combination Therapy With Ramipril Plus Felodipine
The purpose of this study is to evaluate the efficacy of valsartan plus amlodipine in hypertensive patients not responding to treatment with ACE inhibitor plus calcium channel blocker
- Trial name
- NCT00367939
- Testing
- valsartan + amlodipine
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- Novartis
Healthy
Pharmacokinetic Interactions of Candesartan Cilexetil and Amlodipine Besylate
This study is designated to evaluate the pharmacokinetic interactions of candesartan cilexetil and amlodipine besylate in healthy male volunteers.
- Trial name
- CCA (NCT01845272)
- Testing
- candesartan cilexetil 32mg, amlodipine 10mg
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Healthy Volunteers
Drug-drug-interaction Study of Ramipril, Amlodipine and Atorvastatin
Study to determine the potential pharmacokinetic interaction of ramipril (and ramiprilat), atorvastatin as atorvastatin calcium trihydrate and amlodipine as amlodipine besilate at steady state after a multiple oral administration…
- Trial name
- NCT04262765
- Testing
- Ramipril, Amlodipine and Atorvastatin
- Where
- Jordan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Midas Pharma GmbH
Hypertension
Bioequivalence Study (Candesartan 16 mg and Amlodipine 10 mg)
The purpose of this study is to compare the safety and pharmacokinetics of HL068 (Candesartan 16 mg and Amlodipine 10mg) with coadministration of the two separate drugs in healthy male volunteers.
- Trial name
- NCT02988362
- Testing
- HL068 16/10mg, Candesartan 16mg and Amlodipine 10mg
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- HanAll BioPharma Co., Ltd.
Healthy
A Bioequivalence Study of Amlodipine / Valsartan From Amlodipine/Valsartan 10/160 Tablets (Pharmacare, Palestine) and Exforge Tablets (Novartis Pharma, USA)
Comparative randomized, single dose, two-way crossover open-label study to determine the bioequivalence of Amlodipine / valsartan from Amlodipine/Valsartan 10/160 film coated tablets (Pharmacare, Palestine) and Exforge 10/160…
- Trial name
- NCT02519010
- Testing
- Amlodipine/Valsartan, Exforge
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Genuine Research Center, Egypt