Clinical trials: Amlodipine
Hypertension
Efficacy/Safety of Amlodipine Plus Losartan Versus Amlodipine in Patients With Essential Hypertension
The purpose of this study is to evaluate of efficacy and safety of amlodipine plus losartan and amlodipine alone in patients with essential hypertension inadequately controlled on amlodipine monotherapy.
- Trial name
- NCT00940667
- Testing
- Amlodipine plus Losartan, Amlodipine
- Where
- South Korea
- Volunteers
- 185 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Healthy
Bioequivalency Study of Amlodipine Besylate Tablets, 10 mg of Dr. Reddy's Under Fed Conditions
The purpose of this study is to determine the pharmacokinetics and bioequivalence of amlodipine besylate formulations under fed conditions.
- Trial name
- NCT01131936
- Testing
- Amlodipine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Volunteers
Bioequivalence Study of CJ-30059
This study is designed to evaluate the bioequivalence of the two treatments, the administration of CJ-30059 and the co-administration of candesartan cilexetil and amlodipine besylate, in healthy volunteers.
- Trial name
- CCA (NCT02173912)
- Testing
- Candesartan cilexetil 16 mg and Amlodipine besylate 10mg (Reference), CJ-30059 (Test)
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Hypertension
Amlodipine And Olmesartan Medoxomil In Hypertensive Filipino Patients
The purpose of this study is to determine the safety, tolerability and efficacy of Amlodipine and Olmesartan medoxomil among Hypertensive Filipino patients.
- Trial name
- NCT01200407
- Testing
- Amlodipine + Olmesartan medoxomil
- Where
- 51 sites in Philippines
- Volunteers
- 615 people
- Sponsor
- Pfizer
Pharmacokinetics
Combination of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects
The purpose of this study is to evaluate the Pharmacokinetics and safety/tolerability between Fimasartan/Amlodipine/Hydrochlorothiazide and co administration of Fimasartan/Amlodipine and Hydrochlorothiazide in Healthy volunteers.
- Trial name
- NCT03629067
- Testing
- Treatment T, Treatment R
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension
Efficacy and Safety of CKD-828 to Stage 2 Hypertension
The aim of present study is to evaluate the efficacy and safety of two dose combination of S-Amlodipine/Telmisartan (2.5/40mg, 2.5/80mg and 5/80mg) compared with S-Amlodipine monotherapy (2.5mg and 5mg) in patients with Stage 2…
- Trial name
- NCT01634295
- Testing
- CKD-828 2.5/40mg, CKD-828 5/40mg, CKD-828 5/80mg
- Where
- South Korea
- Volunteers
- 103 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension With Hyperlipidemia
Drug-drug Interaction Following Oral Administration of Telmisartan/Amlodipine and Atorvastatin in Healthy Adult Volunteers
study to evaluate drug-drug interaction following oral administration of telmisartan/amlodipine and atorvastatin in healthy adult volunteers
- Trial name
- NCT03461081
- Testing
- telmisartan/amlodipine and atorvastatin
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Hypertension
To Evaluate Real-world Safety, Effectiveness and Appropriate Use of Micatrio® Combination Tablets Treatment in Patients With Hypertension
Study to evaluate real-world safety, effectiveness and appropriate use of Micatrio® Combination Tablets treatment in patients with hypertension
- Trial name
- NCT03021265
- Testing
- T80/A5/H12.5 FDC
- Where
- Japan
- Volunteers
- 676 people
- Sponsor
- Boehringer Ingelheim
Essential Hypertension
Assess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With Amlodipine
The main objective of the study will be to assess the efficacy and safety of Sacubitril/Allisartan (240mg) and Amlodipine (5mg) in patients with essential hypertension uncontrolled after 4-week treatment with Amlodipine (5mg).
- Trial name
- NCT07704684
- Testing
- Experimental: Sacubitril/Allisartan and Amlodipine Group, Active Comparator: Amlodipine Group
- Where
- China
- Volunteers
- 376 people
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Hypertension,Essential
Determining the Optimal Dose of AD-209 in Patients With Essential Hypertension
The purpose of this study is to determine the optimal dose of AD-209 in patients with Essential Hypertension.
- Trial name
- NCT04218552
- Testing
- AD209, Amlodipine low, Amlodipine high
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Addpharma Inc.
Healthy
Pharmacokinetics of Different Formulations of Telmisartan, Amlodipine, and Hydrochlorothiazide (HCTZ) in Japanese Healthy Male Volunteers
To assess drug drug interaction through pharmacokinetics investigation at steady state of Telmisartan, Amlodipine, and Hydrochlorothiazide (HCTZ) given as three different formulations in healthy Japanese male subjects
- Trial name
- NCT02183675
- Testing
- Telmisartan/Amlodipine, Telmisartan/Amlodipine/HCTZ, Telmisartan/HCTZ
- Where
- Japan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Hypertension, Hyperlipidemia
PK Study of YH22189 FDC Compared to Combination of Telmisartan/Amlodipine and Rosuvastatin
This is a Randomized, open-label, single-dose, 3-treatment, 3-period, 3-sequence crossover design.
- Trial name
- NCT02608242
- Testing
- YH22189, Twynsta 80/10mg, Crestor 20mg
- Where
- South Korea
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Essential Hypertension
Comparing Safety and Efficacy of Amlodipine Verses S Amlodipine in Patients With Essential Hypertension
As a third-generation dihydropyridine calcium channel blocker (CCB), Amlodipine is mainly used in a single therapy or combined therapy for hypertension or angina.
- Trial name
- NCT04554303
- Testing
- S-amlodipine 2.5mg, Amlodipine 5mg
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Healthy
A Study to Evaluate the Drug-drug Interaction Between Telmisartan, Amlodipine and Hydrochlorothiazide
A randomized, open-label, single dose, 3-way crossover study to evaluate the drug-drugs interaction between Telmisartan, Amlodipine and Hydrochlorothiazide in healthy male volunteers
- Trial name
- NCT03889145
- Testing
- Telmisartan 80mg, Amlodipine10mg, Hydrochlorothiazide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Healthy
Bioequivalence Trial of Concor AM® vs Bisoprolol and Amlodipine in Chinese Participants
This is a Phase I, open-label, randomized, 2-period, 2-sequence, crossover study to demonstrate bioequivalence (BE) between the bisoprolol-amlodipine fixed-dose-combination (FDC) tablet (investigational product) and bisoprolol…
- Trial name
- NCT03226275
- Testing
- Bisoprolol-Amlodipine FDC, Bisoprolol, Amlodipine
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Essential Hypertension
To Assess Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled With Amlodipine or Allisartan Isoproxil
The main objective of the study will be to assess the efficacy and safety of Allisartan Isoproxil/Amlodipine (240 mg/5 mg) in patients with mild to moderate essential hypertension uncontrolled after 4-week treatment with…
- Trial name
- NCT06465264
- Testing
- Allisartan Isoproxil/Amlodipine group 1, Amlodipine group 1, Allisartan Isoproxil/Amlodipine group 2
- Where
- China
- Volunteers
- 499 people
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Healthy
Influence of Food on the Bioavailability of Telmisartan/Amlodipine Fixed Dose Combination in Healthy Japanese Male Volunteers
Study to investigate the relative bioavailability and pharmacokinetics of the fixed-dose combination tablets (telmisartan 40 mg/amlodipine 5 mg and telmisartan 80 mg/amlodipine 5 mg) in the fed condition compared with those of…
- Trial name
- NCT02261064
- Testing
- Telmisartan/Amlodipine low dose, Telmisartan/Amlodipine high dose, Japanese meal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Hypertension
A Clinical Study to Compare Combination of Aliskiren+ HCTZ to Irbesartan+ HCTZ or Amlodipine+ HCTZ or HCTZ Alone in Obese Hypertensive Not Responsive to HCTZ 25 mg
To evaluate the blood pressure lowering effects of the combination of aliskiren 300 mg and HCTZ 25 mg in obese patients with essential hypertension inadequately treated with HCTZ 25 mg, compared to irbesartan or amlodipine with…
- Trial name
- NCT00219115
- Testing
- aliskiren
- Where
- 2 sites in United States, Germany
- Volunteers
- 493 people
- Sponsor
- Novartis
Hypertension
Controlled Release Nifedipine and Valsartan Combination Therapy in Patients With Essential Hypertension
The primary objective of this study is to investigate incremental cost effectiveness of Nifedipine CR and Amlodipine in combination therapy with Valsartan for the treatment of essential hypertensive patients.
- Trial name
- NCT01518855
- Testing
- Nifedipine (Adalat, BAYA1040), Amlodipine (Norvasc), Diovan
- Where
- 4 sites in Japan
- Volunteers
- 514 people
- Sponsor
- Bayer
Healthy Male Volunteers
CKD-828 Drug Interaction Study (Telmisartan)
The purpose of this study is to evaluate the Pharmacokinetic drug interaction and safety of Telmisartan between free combination of Telmisartan and S-amlodipine and Telmisartan monotherapy.
- Trial name
- NCT01356017
- Testing
- Telmisartan 80mg, S-amlodipine 5mg, Telmisartan 80mg
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical