Clinical trials: Celecoxib
Pharmacokinetics
A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult Subject
This is an open-label, randomized, multiple-dose, two-treatment, two-period crossover study comparing the test and reference products.
- Trial name
- NCT05436678
- Testing
- PrimeC 748 mg, Ciprofloxacin 750 MG, Celecoxib 200mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- NeuroSense Therapeutics Ltd.
Alzheimer Disease
A Phase 2, Randomized, Prospective Double-Blind, Single-Center, Placebo-controlled Study to Evaluate Safety, Tolerability, Target Engagement, and Efficacy of PrimeC in Patients With Mild to Moderate Alzheimer's Disease.
20 subjects with mild to moderate AD will be enrolled in the study and randomized at a 1:1 ratio to receive the study drug or placebo tablets, respectively.
- Trial name
- RoAD (NCT06185543)
- Testing
- PrimeC
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- NeuroSense Therapeutics Ltd.
Post Operative Pain
A Phase 3 Study of F14 for Management of Pain Following Total Knee Replacement
This is a Phase 3, randomized, double blind, multicenter study to evaluate the analgesic efficacy and safety of a single intra-articular dose of F14 (625 mg sustained release celecoxib) administered concurrent with multimodal…
- Trial name
- NCT05603832
- Testing
- F14, 0.25 % Bupivacaine HCl, Acetaminophen
- Where
- 7 sites in United States
- Volunteers
- 151 people
- Sponsor
- Arthritis Innovation Corporation
Knee Osteoarthritis
Study of the Effect of Chondroitin Sulfate on Structural Changes in Knee Osteoarthritis Patients Assessed by MRI
The main purpose of this study is to compare the cartilage volume loss at the Baseline visit and after 24 months of treatment in patients treated with CHONDROITIN SULPHATE (CONDROSAN) 1200 mg daily vs.
- Trial name
- MOSAIC (NCT01354145)
- Testing
- Chondroitin sulfate, Celecoxib
- Where
- 5 sites in Canada
- Volunteers
- 194 people
- Sponsor
- Bioiberica
Ankle Sprain
Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain
To assess the efficacy of celecoxib loading dose of 400mg followed by 200 mg twice a day (BID) versus oral non-selective NSAIDs in acute pain due to ankle sprain.
- Trial name
- NCT00446797
- Testing
- Non-selective NSAIDS, Celecoxib
- Where
- 16 sites in Brazil, Costa Rica and 6 more
- Volunteers
- 278 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Metastatic Prostate Cancer
Phase II Trial of Docetaxel and Celecoxib in Patients With Androgen Independent Prostate Cancer
A multi-center controlled, non-comparative open Phase II trial of docetaxel and celecoxib in patients with metastatic androgen independent prostate cancer where efficacy is measured by PSA response defined as a 50% reduction in…
- Trial name
- NCT00494338
- Testing
- Docetaxel
- Where
- Brazil
- Volunteers
- 6 people
- Sponsor
- Sanofi
Pain
Experimental Biomarker Study for Pain Thresholds
The purpose of this study is to characterize the heat pain tolerance threshold (HPTolTr) in primary hyperalgesic skin after topical capsaicin application, and to assess heat pain and mechanical thresholds (eg, pressure pain…
- Trial name
- NCT02695745
- Testing
- V116517 aqueous suspension, Celecoxib capsules, Capsaicin
- Where
- Denmark
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Purdue Pharma LP
Healthy Volunteer
Phase I Study to Evaluate Bioavailability of Overencapsulated Celecoxib
Phase I study designed to test the hypothesis that overencapsulated celecoxib 200 mg qd is bioequivalent to commercial celecoxib 200 mg qd.
- Trial name
- NCT00729495
- Testing
- celecoxib
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- POZEN
Arthritis, Juvenile Rheumatoid
A Study To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects
This Is A Multicenter, Active-Controlled Trial To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects With Juvenile Idiopathic Arthritis
- Trial name
- NCT00807846
- Testing
- Celecoxib, Naproxen
- Where
- 39 sites in United States, Chile and 8 more
- Volunteers
- 201 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Amyotrophic Lateral Sclerosis, ALS
Open Label Study to Evaluate Ciprofloxacin/Celecoxib Combination in Patients With ALS
This is an open label, off label study, to provide interested ALS patients with Ciprofloxacin/Celecoxib fixed dose combination, while assessing safety and tolerability and routine disease progression measures (ALSFRS-R and Vital…
- Trial name
- NCT04165850
- Testing
- Fixed dose combination Ciprofloxacin/Celecoxib
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- NeuroSense Therapeutics Ltd.
Healthy Volunteers
Study Of Celecoxib In Healthy Subjects
A study to confirm the superiority of celecoxib 100 mg BID to loxoprofen 60 mg TID in the incidence of gastroduodenal endoscopic ulcers after 2 weeks treatment.
- Trial name
- NCT00994461
- Testing
- Celecoxib, Loxoprofen
- Where
- 3 sites in Japan
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Acute Pain
A Study of LY3023703 Testing Pain Relief After Wisdom Teeth Removal
The main purpose of this study is to test if a single dose of LY3023703 relieves pain after wisdom teeth removal. The study will last about one week for each participant, not including screening.
- Trial name
- NCT01872910
- Testing
- LY3023703, Celecoxib
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Dental Pain
Study of Diclofenac Capsules to Treat Dental Pain
The purpose of this study is to determine whether Diclofenac Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT00985439
- Testing
- Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Healthy Volunteers
A Pilot Open-Label Crossover Bioavailability Study of Celecoxib in Healthy Volunteers
A pharmacokinetic study in healthy volunteers to determine the relative bioavailability of three formulations of celecoxib to the approved formulation.
- Trial name
- NCT00813241
- Testing
- celecoxib reference formulation, celecoxib test formulation A1, celecoxib test formulation B2
- Where
- Singapore
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain
Study To Evaluate Efficacy And Safety Of An Additional Dose Of Celecoxib (YM177) In Patients With Post-Tooth Extraction Pain
To evaluate efficacy and safety of additional dose of celecoxib, as compared to placebo, in patients with post lateral mandibular impacted third molar tooth extraction pain.
- Trial name
- NCT01062113
- Testing
- Celecoxib
- Where
- 22 sites in Japan
- Volunteers
- 255 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.