Clinical trials: Cognitive training
Insomnia
STATE Trial: SusTained Attention Training to Enhance Sleep
This study is a validation study to document the acceptability of the Tonic and Phasic Alertness Training (TAPAT) training program in older adults with chronic late-life insomnia.
- Trial name
- STATE (NCT02921074)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Posit Science Corporation
Depression, Anxiety
Meru Health Program to Treat Depression in Primary Care
Meru Health Inc. seeks to further validate the Meru Health Program (MHP) as a single solution to screening, referral, and treatment in primary care as compared to treatment as usual using a Randomized Controlled Trial (RCT) study…
- Trial name
- NCT05615662
- Testing
- Meru Health Program, Treatment as Usual
- Where
- United States
- Sponsor
- Meru Health, Inc.
Multiple Sclerosis, Lung Cancer
An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer
CT-100 is a platform that provides interactive, software based therapeutic components that may be used as part of a treatment in future software-based prescription digital therapeutics.
- Conditions
- Multiple Sclerosis, Lung Cancer, Breast Cancer
- Trial name
- NCT06136923
- Testing
- CT-100-D-004-A, CT-100-D-004-B
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- Click Therapeutics, Inc.
Depressive Disorder, Major Depressive Disorder
Study of Virtual Reality-based Medical Device for Patients with Depressive Disorder
This study apply a wearable visual device (HMD)-VR-based software medical device for patients with depressive disorder for 8 weeks.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Depressive Episode
- Trial name
- NCT05701345
- Testing
- OMNIFIT DTx-MDD, standard treatment
- Where
- 5 sites in South Korea
- Volunteers
- 162 people
- Sponsor
- Omni C&S
Schizophrenia
Creating Live Interactions to Mitigate Barriers
This study is a validation study to evaluate the acceptability, feasibility and impact of a mobile psychosocial intervention to enhance social functioning in people with schizophrenia.
- Trial name
- CLIMB (NCT03317769)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training, Optimized social skills training
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Posit Science Corporation
Cognitive Impairment, Mild
Telerehabilitation Cognitive Impairments Following Chemotherapy Feasibility Study
Develop a game-based upper-extremity motor and cognitive rehabilitation system using custom and adaptable virtual reality simulations on a wearable device enhanced with biosensors.
- Trial name
- TCIFCF (NCT04972019)
- Testing
- Telerehabilitation Experimental Group
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Bright Cloud International Corp
Tinnitus, Hearing Loss
Neuro-feedback Therapy for Treating Tinnitus
Neuro-feedback for treating tinnitus seem to be a promising approach to help people suffering from chronic tinnitus. The past studies on this approach suffered interindividual variability in their results.
- Trial name
- TNTA (NCT03773926)
- Testing
- Neuro-feedback therapy
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Zeta Technologies
Alzheimer's Disease
Computer-Based Training for Mild Alzheimer's Disease
The primary objective of this study is to evaluate the effects of computer-based training program ("HiFi-AD") on the memory and cognitive abilities of individuals diagnosed with mild Alzheimer's Disease (AD).
- Trial name
- NCT00319891
- Testing
- Computer-based Cognitive Training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Posit Science Corporation
Chronic Pain, Low Back Pain
Development and Evaluation of Computerized Chemosensory Based Orbitofrontal Networks Training for Treatment of Pain
The overarching goal of this study phase, Phase I component is to configure Computerized Chemosensory-Based Orbitofrontal Networks Training (CBOT) into Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment…
- Trial name
- CBOT-Pain (NCT06218407)
- Testing
- Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) short burst paradigm, Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) long burst paradigm, Computerized Chemosensory-Based Orbitofrontal Cortex Training plus beta caryophyllene (CBOT-Plus)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Evon Medics LLC
Insomnia
Remote STATE Training for Insomnia in Older Adults
This study called rSTATE (Remote STATE Training for Insomnia in Older Adults) is a Phase II study to definitively evaluate the efficacy of a computerized cognitive training program (rSTATE) designed to improve sleep regulation…
- Trial name
- rSTATE (NCT06589024)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Posit Science Corporation
Depression, Insomnia
PracticeGround: Transforming Training and Delivery of Mental Health EBPs
The ultimate goal is to facilitate the delivery of empirically supported treatments (ESTs) for mental disorders and to improve client mental health outcomes.
- Conditions
- Depression, Insomnia, Suicide
- Trial name
- NCT02314624
- Testing
- Behavioral Activation for Depression, Cognitive Behavior Therapy for Insomnia, Collaborative Assessment and Management of Suicidality, Care-as-Usual Psychotherapy
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Aging
Improvement in Memory With Plasticity-Based Adaptive Cognitive Training (IMPACT)
The primary objective of this study is to evaluate the effects of a computer-based training program on the memory and cognitive abilities of mature individuals undergoing healthy aging.
- Trial name
- IMPACT (NCT00283010)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Educational DVDs
- Where
- United States
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation
Vascular Cognitive Impairment no Dementia
Mexidol® Efficacy and Safety in Treatment of VCIND in Older Adults
The primary objective of this study is to evaluate the efficacy of Mexidol® sequential parenteral and oral administration as part of comprehensive therapy in older adults with chronic brain ischemia and vascular cognitive…
- Trial name
- NCT07700615
- Testing
- Mexidol, Standard Therapy
- Where
- 4 sites in Russia
- Volunteers
- 120 people
- Sponsor
- Pharmasoft
Hearing Loss, Age-Related
Evaluation of a Digital Therapy of Auditory Training
The aim of the study is to evaluate the efficiency of the medical device AUDISSEE in improving the perception in noise ability of presbycusis patients with hearing-aids.
- Trial name
- AUDISSEE (NCT05848661)
- Testing
- AUDISSEE
- Volunteers
- 240 people
- Sponsor
- Humans Matter
Age Related Cognitive Decline
Improvements in Cognitive Skills of Older Adults Using Dynamic Visual Attention Training
The proposed SBIR Phase I study tests the feasibility of PATH neurotraining for improving cognitive skills in older adults and, potentially, forestalling or protecting against cognitive decline and dementia.
- Trial name
- NCT03456986
- Testing
- PATH neurotraining, Orientation Discrimination
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Perception Dynamics Institute
Mild Cognitive Impairment, MCI
Cognitive Therapy Software for Improving Cognitive Function for Patients With Mild Cognitive Impairment
Cognitive therapy software for improving cognitive function for patients with mild cognitive impairment
- Trial name
- SB-DEX (NCT06264557)
- Testing
- SB-100, Educational book
- Where
- 12 sites in South Korea
- Volunteers
- 140 people
- Sponsor
- Rowan
Cognitive Function Abnormal
Boost Study 21270 (Cognition)
This study is designed to to test the technical feasibility of encouraging interaction with a mobile smartphone software package (mHealth app) for training aspects of executive function and cognition.
- Trial name
- NCT05990335
- Testing
- mHealth application (custom)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- NXTech
Chronic Pain, Low Back Pain
Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)
The overarching goal of this study phase, Phase II component is to perform a randomized clinical trial of the refined Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain [CBOT-Pain (or CBOT-P)]…
- Trial name
- CBOT-P-2 (NCT06671132)
- Testing
- Computerized Chemosensory-Based Orbitofrontal Cortex Training for Pain, Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT)
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Evon Medics LLC
Traumatic Brain Injury (TBI), Acquired Brain Injury
LearningRx Cognitive Training for Brain Injury
The purpose of this investigation is to conduct a series of case studies on the impact of LearningRx cognitive training on cognitive skills, daily functioning, and workplace self-efficacy for participants with Traumatic Brain…
- Conditions
- Traumatic Brain Injury (TBI), Acquired Brain Injury, Post COVID-19 Cognitive Impairment
- Trial name
- NCT02918994
- Testing
- LearningRx cognitive training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gibson Institute of Cognitive Research
Major Depressive Disorder
Piloting a Novel, Mobile Cognitive Training Tool for Patients With Major Depressive Disorder (MDD)
To assess the efficacy of a mobile-device-deployed cognitive emotional treatment for depression (Moodify) versus an active control treatment (commercially available computer games).
- Trial name
- MDD (NCT02922556)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation