Clinical trials: Ibuprofen
Pain
An Effectiveness and Safety Study Comparing Acetaminophen (3900 mg/Day) to Ibuprofen (1200 mg/Day) in the Treatment of Post-Race Muscle Soreness.
The purpose of this study is to compare the effectiveness and safety of acetaminophen extended release caplets and ibuprofen in relieving the muscle soreness that occurs after a marathon.
- Trial name
- NCT00240838
- Testing
- acetaminophen extended release caplets
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Fever
A Study of Ibuprofen 250 mg / Acetaminophen 500 mg Comparing The Antipyretic Effects in Healthy Male Volunteers
This is a single dose study that will evaluate the efficacy and safety of a Fixed Dose Combination Ibuprofen 250 mg/ Acetaminophen 500 mg tablet in healthy male patients with fever.
- Trial name
- NCT02761980
- Testing
- Ibuprofen 250 mg / Acetaminophen 500 mg, Ibuprofen 250 mg, Acetaminophen 500 mg
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Pfizer
Migraine, Headache
Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nuromol® Tablets (200mg Ibuprofen/ 500mg Paracetamol)
Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare Ibuprofen/ Paracetamol tablets (200mg Ibuprofen/ 500mg Paracetamol) versus Nuromol® tablets (200mg Ibuprofen/ 500mg…
- Conditions
- Migraine, Headache, Backache
- Trial name
- NCT06180070
- Testing
- Ibuprofen/ Paracetamol tablets, Nuromol® tablets
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Pain
Study Comparing the Efficacy of Two Ibuprofen Formulations
This is a study of healthy volunteers to compare how quickly different ibuprofen products relieve dental pain.
- Trial name
- NCT00740857
- Testing
- ibuprofen Formulation 1, ibuprofen Formulation 2
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Postsurgical Pain Due to Third Molar Extraction
An Analgesic Study to of V117957 for the Treatment of Postsurgical Pain Due to Third Molar Extraction
The primary objective of this study is to assess the analgesic properties of an oral dose of V117957 4.5 mg aqueous suspension in the third molar extraction model
- Trial name
- NCT01900795
- Testing
- V117957, Ibuprofen
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Purdue Pharma LP
Pain
Efficacy and Safety of Ibuprofen in Patients With Ankle Injuries
The objective of the study is to evaluate the efficacy and safety of Ibuprofen in patients with ankle injuries.
- Trial name
- NCT01563289
- Testing
- Ibuprofen
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- Orion Corporation, Orion Pharma
Postoperative Pain
To Evaluate the Safety, Tolerability and Analgesic Efficacy of SAF312 in Postoperative Dental Pain Patients
The study will assess the analgesic efficacy and safety and tolerability of a single oral dose of SAF312 in postoperative dental pain patients after 3rd molar extraction.
- Trial name
- NCT00986882
- Testing
- SAF312A, Ibuprofen
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Novartis
Fever
Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children
The purpose of this study was to compare the efficacy and tolerability of acetaminophen, dipyrone and ibuprofen to fever control in children.
- Trial name
- NCT01359020
- Testing
- ibuprofen, dipyrone, acetaminophen
- Where
- Brazil
- Volunteers
- 396 people
- Sponsor
- Mantecorp Industria Quimica e Farmaceutica Ltd.
Delayed Onset Muscle Soreness, DOMS
Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness (DOMS)
This is a Phase 3, prospective, randomized, dual-center, double-blind, placebo-controlled, parallel-group study designed to determine the efficacy and safety of SST-0225 (5.4 grams, applied up to 6 times in 24 hours, over a…
- Trial name
- DOMS (NCT02597634)
- Testing
- SST-0225
- Where
- 3 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC
Analgesics
A Safety Trial to Compare Different Analgesics in Combination With Low Dose Aspirin to Study Their Bleeding Properties and Their Effects on the Stomach
The purpose of this study is to compare several analgesics given in approved daily doses in combination with a daily cardioprotective dose of aspirin (81 mg), to study their bleeding properties and their effects on the stomach in…
- Trial name
- NCT00261586
- Testing
- aspirin, acetaminophen, ibuprofen, naproxen, celecoxib, rofecoxib
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Healthy
Effects of ICA-105665 Using the Intradermal Capsaicin and Ultraviolet B (UV-B) Models in Healthy Male Subjects
The purpose of this study is; to determine the pharmacodynamic (PD) effects of ICA-105665 using the intradermal (ID) capsaicin model in healthy male subjects, and to investigate the effect of ICA-105665 on inflammatory…
- Trial name
- NCT00962663
- Testing
- ICA-105665, Ibuprofen
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Bioequivalence Study Of Ibuprofen 50mg/ml (laboratórios Pfizer Ltda) In The Oral Suspension Form.
An open label, randomized, 2x2 crossover, single dose, phase 4 study to determine the pharmaceutical bioequivalence of ibuprofen 50mg/ml (laboratórios pfizer ltda) oral suspension versus alivium ® 50mg/ml (mantecorp indústria…
- Trial name
- B4371004 (NCT01350596)
- Testing
- Alivium®, Ibuprofen
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Fever
A Study of Caldolor in Hospitalized Febrile Pediatric Patients
The primary objective of this study of Caldolor administered to febrile hospitalized pediatric patients every 6 hours for 24 hours is to determine the clinical equivalence of a single dose of Caldolor compared to acetaminophen…
- Trial name
- NCT00225706
- Testing
- Caldolor
- Where
- 3 sites in United States, Panama and 1 more
- Sponsor
- Cumberland Pharmaceuticals
Osteoarthritis, Rheumatoid Arthritis
Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501, a fixed-dose combination oral tablet of 800 mg ibuprofen and 26.6 mg famotidine for patients that require long-term NSAID treatment.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- NCT00984815
- Testing
- HZT-501
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Amgen
Pneumococcal Vaccines
Study Assessing the Effect of Medications to Prevent Fever on Prevenar 13®
The purposes of this study are assess the immunological response (measure the amount of antibodies, i.e. proteins that fight off germs) produced by children after they have been given the 13-valent pneumococcal vaccine (13vPnC)…
- Trial name
- NCT01392378
- Testing
- 13-valent pneumococcal conjugate vaccine, INFANRIX hexa, Paracetamol
- Where
- 14 sites in Poland
- Volunteers
- 908 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pain
Self Selection Trial of Naproxen Sodium
A pilot trial to demonstrate that consumers can appropriately select Aleve 24 Hour for their own use based on expected duration of pain greater than 12 hours.
- Trial name
- KEIFER SST (NCT01383486)
- Testing
- Naproxen sodium ER (BAYH6689), Advil
- Where
- 10 sites in United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Bayer
Glycogen Storage Disease Type III
Safety, Tolerability, and Pharmacokinetics of UX053 in Patients With Glycogen Storage Disease Type III (GSD III)
The primary objective of the study is to evaluate the safety of UX053 in adults with Glycogen Storage Disease Type III (GSD III).
- Trial name
- NCT04990388
- Testing
- UX053, Antipyretic, H2 Blocker
- Where
- 6 sites in United States, Italy and 1 more
- Volunteers
- 9 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Uterine Fibroids, Polyps
Comparative Sedation Study of the MyoSure Hysteroscopic Tissue Removal System
The purpose of this study is to develop a recommended local anesthetic protocol and post-treatment pain management regimen, in order to assure patient comfort during office-based treatment with the MyoSure Hysteroscopic Tissue…
- Trial name
- NCT00979342
- Testing
- Hysteroscopic Morcellator
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Hologic, Inc.
Opioid Use, Arthropathy of Knee
RelieVRx for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use
This is a single-center, prospective, randomized, controlled study of the appliedVR RelieVRx headset in subjects undergoing Total Knee Arthroplasty (TKA).
- Conditions
- Opioid Use, Arthropathy of Knee, Pain, Postoperative
- Trial name
- NCT04010266
- Testing
- RelieVRx headset, multi-modality pain management
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- AppliedVR Inc.
Common Cold
Evaluation of the Efficacy and Safety of Two Ibuprofen Combination Products for the Treatment of the Common Cold and Flu in Latin America
This is a multicenter, prospective, randomized, double-blind, triple-dummy, parallel group, comparative, study designed to evaluate the efficacy of Ibuprofen (IBU) 200 mg/ Phenylephrine (PE) 10 mg and IBU 200 mg/ PE 10 mg/…
- Trial name
- NCT01938144
- Testing
- Advil Congestion Relief, Advil Allergy and Congestion Relief, Paracetamol
- Sponsor
- Pfizer