Clinical trials: Intervention Group
Type 2 Diabetes Mellitus (T2DM)
Interventional Study of Active Weight Management in Patients With Type 2 Diabetes and Obesity in Routine Clinical Practice During 12 Months.
This study was aimed to achieve of long-term weight loss in T2DM patients by use of comprehensive lifestyle changes program, providing patients with structured diet, exercise plan, group behavioral support and group education.
- Trial name
- NCT02670928
- Testing
- Lifestyle intervention
- Where
- 2 sites in Russia
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Crohn Disease and Ulcerative Colitis
Bacillus Probiotic Spores in Supporting the Treatment of Chronic Inflammatory Bowel Disease
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a chronic relapsing intestinal disorder driven by immune dysregulation, impaired mucosal barrier function, and gut microbiome dysbiosis.
- Trial name
- NCT07799428
- Testing
- RO, LiveSpo® DIA30, LiveSpo® COLON
- Where
- Vietnam
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Ultrasound Imaging of Anatomical Structures
Clinical Validation of Nerveblox, an Artificial Intelligence Software to Support Ultrasound-Guided Regional Anesthesia Procedures
This single-center, prospective study is being conducted at AABP Integrative Pain Care and Wellness in Brooklyn, New York, USA. The aim of this study is to collect ultrasound images from healthy volunteers and evaluate the…
- Trial name
- NCT06878911
- Testing
- Ultrasound Scans
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Smart Alfa Teknoloji San. ve Tic. A.S.
Psychological Stress
Essential Oil Inhalation and Acute Stress Response in Healthy Adults
This randomized, double-blind, placebo-controlled study evaluates the acute physiological and subjective responses to essential oil inhalation in healthy adults.
- Trial name
- DMA (NCT07473544)
- Testing
- Essential Oil Inhalation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
Prosthetic Fixation After Cementless Total Hip Arthroplasty
The Efficacy Study of Aclasta on Prosthetic Fixation in Postmenopausal Women After THA
It's to investigate the efficacy of Zoledronic acid treatment on the early prosthetic fixation in post-menopausal osteoporosis women under cementless total hip arthroplasty after 24-month observation.
- Trial name
- NCT02333344
- Testing
- Zoledronic acid 5mg
- Where
- China
- Sponsor
- Novartis Pharmaceuticals
Malnutrition
Compliance With a High Energy Content, Low Volume Oral Nutritional Supplement
This study aims to investigate the compliance of high-energy, low-volume oral nutritional supplements (ONS) compared to equivalent high-energy standard ONS (control) in participants at risk of malnutrition.
- Trial name
- NCT05609006
- Testing
- High-Energy, Low-Volume ONS, High-Energy Standard ONS
- Where
- 2 sites in Spain
- Volunteers
- 73 people
- Sponsor
- Danone Specialized Nutrition
Bone Deformity
Clinical Study of Bone Graft Substitutes in Orthopaedic and Spinal Applications.
This is an observational, prospective, non-randomised, multi-centred post market clinical follow-up study to compile real world clinical data on safety and efficacy of the synthetic bone graft substitutes in a commercial clinical…
- Trial name
- ROSA (NCT03570606)
- Testing
- bone graft substitute
- Where
- 7 sites in United Kingdom
- Volunteers
- 220 people
- Sponsor
- Ceramisys Ltd
Diabetes Mellitus, Type 2
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Canada, as Part of Local Clinical Practice
The purpose of the study is to collect information on how Rybelsus® works in people with type 2 diabetes and to see if Rybelsus® can lower participants blood sugar levels.
- Trial name
- PIONEER REAL (NCT04559815)
- Testing
- Oral Semaglutide
- Where
- 2 sites in Canada
- Volunteers
- 194 people
- Sponsor
- Novo Nordisk A/S
Vaccination
Evaluation of the Safety and Immunogenicity of Hepatitis A Vaccine
Subjects will be recruited and divided into 3 groups: 1. Hepatitis A（Live）Vaccine，Freeze-dried produced by Changchun Institute of Biological Products Co., Ltd 2.
- Trial name
- NCT04612634
- Testing
- Hepatitis A (Live) Vaccine, Freeze-dried produced by Changchun, Hepatitis A (Live) Vaccine, Freeze-dried produced by Zhejiang, Hepatitis A (Live) Vaccine, Freeze-dried produced by the Institute of Medical Biology, CAMS
- Where
- 2 sites in China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Emphysema
Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function
EMPROVE is a multicenter, prospective, randomized, controlled study designed to evaluate the safety and long-term effectiveness of the Spiration Valve System in patients with emphysema.
- Trial name
- EMPROVE (NCT01812447)
- Testing
- Spiration Valve System, Medical Management
- Where
- 34 sites in United States, Canada
- Volunteers
- 172 people
- Sponsor
- Olympus Corporation of the Americas
Crohn's Disease
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease
The purpose of this study is to evaluate the efficacy of JNJ-78934804 at Week 48 compared to guselkumab and golimumab.
- Trial name
- DUET-CD (NCT05242471)
- Testing
- Guselkumab, Golimumab, JNJ-78934804
- Where
- 456 sites in United States, Australia and 34 more
- Volunteers
- 703 people
- Sponsor
- Janssen Research & Development, LLC
Psoriasis
Effectiveness of a Digital Health Application for Psoriasis
This clinical trial with 348 patients with psoriasis aims to investigate the effectiveness of a self-guided online program for patients with psoriasis.
- Trial name
- NCT06027034
- Testing
- Online program for psoriasis (GAIA-PSO-01)
- Where
- Germany
- Volunteers
- 348 people
- Sponsor
- Gaia AG
Infant, Very Low Birth Weight
Randomized Study of Human-Milk Based Nutrition Versus Formula in Premature Infants
The purpose of this study is to determine whether very low birth weight infants (less than or equal to 1250g or about 2 3/4 pounds) born prematurely fed a diet of only human milk and human milk-derived nutrition have better…
- Trial name
- NCT00506584
- Testing
- Pasteurized human milk and pasteurized human milk fortifier, Human milk fortifier (bovine-based), pre-term formula, Pre-term/term formula
- Where
- 13 sites in United States, Austria
- Volunteers
- 260 people
- Sponsor
- Prolacta Bioscience
Diastolic Heart Failure NYHA Class III-IV, Diastolic Dysfunction Secondary to Aortic Stenosis
CORolla™ TAA for Heart Failure and Preserved Ejection Fraction and Diastolic Dysfunction
The study purpose is to evaluate the safety and feasibility of the CORolla™ TAA in two treatment groups, "CORolla™ Stand-alone group" and " AVR \& CORolla™ Add on group".
- Trial name
- NCT01956526
- Testing
- CORolla™ TAA device
- Where
- 2 sites in Italy
- Volunteers
- 12 people
- Sponsor
- CorAssist Cadiovascular Ltd.
Urinary Bladder, Overactive
A Study to Investigate How Effective and Safe Solifenacin Succinate Suspension is in Treating Children/Adolescents Aged 5 to Less Than 18 Years With Symptoms of Overactive Bladder (OAB) Compared to a Non-active Drug
Solifenacin succinate as a tablet formulation is already on the market for the treatment of symptoms of overactive bladder in adults.
- Trial name
- LION (NCT01565707)
- Testing
- Solifenacin Succinate Suspension, Urotherapy
- Where
- 46 sites in United States, Belgium and 14 more
- Volunteers
- 189 people
- Sponsor
- Astellas Pharma Europe B.V.
Chronic Sinusitis
Efficacy of Post-FESS Implantation of Composite Removable Sinus Stent to Prevent Post-Operative Complications
This is a randomized controlled first in man study. Study purpose is to assess safety and efficacy of Composite Removable Stent Composite Stent implantation post-endoscopic sinus surgery in terms of: Sinus tissue adhesions Middle…
- Trial name
- NCT02812199
- Testing
- Composite Removable Sinus Stent, adrenaline-lidocaine, cold saline wash
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- STS Medical
Asthma
Cross-sectional Study for Identification and Description of Severe Asthma Patients
This will be a non-drug interventional cross-sectional study, where the screening visit and study visit can occur on the same day. Investigational product will not be administered.
- Trial name
- NCT02293265
- Testing
- Short Acting Beta Agonist (SABA)
- Where
- 74 sites in United States, Australia and 4 more
- Volunteers
- 767 people
- Sponsor
- GlaxoSmithKline
Multiple Sclerosis
Open, Multicentric, Prospective, Quality of Life Study in Multiple Sclerosis Patients
To evaluate the evolution of the impact on daily life activities over the first 12 months following the introduction of interferon beta-1b treatment in patients presenting RRMS or patients at high risk of developing Multiple…
- Trial name
- NCT00928967
- Testing
- Interferon beta-1b, (Betaseron BAY86-5046)
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Bayer
Cataract
Cataract Surgery: Femto LDV Z8 Versus Conventional
The aim of the study is to demonstrate the performance and safety of the Femtosecond laser-assisted anterior capsulotomy and lens fragmentation on human eyes using the FEMTO LDV Z8 compared to conventional technique in cataract…
- Trial name
- COMFORT (NCT02351271)
- Testing
- Femto LDV Z8, Manual capsulorhexis&lens fragmentation
- Volunteers
- 130 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Surgical Site Infection
Air Barrier System for the Prevention of Surgical Site Infection
Airborne particles are present in all indoor environments including the operating room. Most of these particles come from the surgical staff moving around in the room, positioning of the patient during surgery, and the movement…
- Trial name
- ABS (NCT01610271)
- Testing
- Air Barrier System
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Nimbic Systems, LLC
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.