Clinical trials: Intervention Group
Surgery
Calibration and Validation of Masimo's O3 Regional Oximetry Device in Neonates, Infants and Children
The study will collect cerebral oximetry data from pediatric and neonatal subjects using the Masimo O3 regional oximetry device, for the purposes of device calibration and validation.
- Trial name
- NCT03123354
- Testing
- O3 regional oximeter sensor
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Masimo Corporation
H. Pylori Infection
The Efficacy of Treatment for Helicobacter Pylori Infection in Preschooler by Yoghurt With LG21
The goal of this non-randomized, open-label, interventional trial is to study the efficacy of treatment for Helicobacter Pylori Infection in Preschooler aged 4-6 by Meiji Yoghurt with LG21.
- Trial name
- NCT06045494
- Testing
- Meiji Yogurt Group
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Meiji China Investment Co.,Ltd
Cytochrome P450 CYP2D6 Enzyme Deficiency, Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM
This randomized controlled trial will evaluate whether the use of pharmacogenetic testing through a Medication Therapy Management (MTM) program has a beneficial impact on drug therapy problems.
- Conditions
- Cytochrome P450 CYP2D6 Enzyme Deficiency, Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant, Ultrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant, Extensive Metabolizer Due to Cytochrome P450 CYP2D6 Variant
- Trial name
- NCT02428660
- Testing
- Pharmacogenetic testing, Software-based drug & gene interaction risk analysis, MTM
- Where
- United States
- Volunteers
- 341 people
- Sponsor
- Genelex Corporation
Articular Cartilage Lesion of Knee
Study to Assess the Safety of Treatment of Articular Cartilage Lesions With CartiLife®
The purpose of this study is to assess the safety and efficacy of implanting bead-type autologous chondrocytes (CartiLife®) obtained by culturing expanded costal chondrocytes of the patient with a chondral defect in the knee.
- Trial name
- NCT03517046
- Testing
- CartiLife
- Volunteers
- 6 people
- Sponsor
- Biosolution Co., Ltd.
Water Intake
A Three-Group Study to Examine the Efficacy of the Air up® Drinking System at Improving Hydration and Associated Health Outcomes
A randomized, controlled trial evaluating the air up® drinking system's impact on hydration and health outcomes. Participants will use air up® with Peach, Orangeade, or unscented pods and their effects on drinking habits, and…
- Trial name
- NCT06290479
- Testing
- Air Up® Peach Pod, Air Up® Orangeade Pod
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- air up GmbH
Cancer
Regulatory TYKERB® Tablets PMS
Non-interventional, open-label, single group, multicentric post-marketing surveillance to monitor the safety and effectiveness of TYKERB® tablets administered in Korean patients according to the prescribing information TYKERB® is…
- Trial name
- NCT00975988
- Testing
- TYKERB® tablets
- Where
- 2 sites in South Korea
- Volunteers
- 750 people
- Sponsor
- GlaxoSmithKline
Growth Disorders, Dietary Exposure
Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns
This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years.
- Conditions
- Growth Disorders, Dietary Exposure, Child Development, Bone Development Abnormal
- Trial name
- NCT06329388
- Testing
- TruHeight Growth Protein Shake
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TruHeight Vitamins
Scarring
Amniotic Membrane in Decompressive Craniectomy to Reduce Scarring
The purpose of this study is to evaluate the effectiveness of dHACM in reducing scar tissue formation in craniectomy patients as well as facilitating reoperation and repair.
- Trial name
- NCT02033824
- Testing
- dHACM, Craniectomy
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- MiMedx Group, Inc.
Migraine, Medication Overuse Headache
Eptinezumab in Adults With Migraine and Medication Overuse Headache
This study evaluates the efficacy of eptinezumab to prevent migraine and headache in patients with the combined diagnosis of migraine and medication overuse headache
- Trial name
- Sunlight (NCT04772742)
- Testing
- Eptinezumab
- Where
- 40 sites in China, Georgia and 3 more
- Volunteers
- 193 people
- Sponsor
- H. Lundbeck A/S
Ovarian Cancer, Endometrial Cancer
Biomarkers for Gynecologic Cancer
A novel blood metabolic biomarker, AminoIndexTM (gynecological), was developed for gynecological cancers from over 400 Japanese patient's plasma free amino acid profiles (PFAAs) by a rapid and sensitive LC-MS (Liquid…
- Conditions
- Ovarian Cancer, Endometrial Cancer, Benign Gynecological Disease
- Trial name
- NCT02178462
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Ajinomoto Co., Inc.
Preterm Birth, Low; Birthweight, Extremely (999 Grams or Less)
Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - MHSB
This study evaluates the use of a NICU clinical integration system (Dashboard and accessories) in improving the quality of care delivered, patient health outcomes, and parent and clinician satisfaction.
- Conditions
- Preterm Birth, Low; Birthweight, Extremely (999 Grams or Less), Neonatal Infection, Satisfaction
- Trial name
- NCT03673579
- Testing
- NICU Dashboard
- Where
- United States
- Sponsor
- Philips Healthcare
Healthy Adult Women
Study of the Effect of a Fermented Dairy Product on Gastrointestinal Well Being in Adult Women
The purpose of this study is to evaluate the effect of a commercially available fermented dairy product containing probiotics (4 weeks, twice a day) on the improvement of gastrointestinal well being and digestive symptoms in…
- Trial name
- NCT01388010
- Testing
- 1-Fermented Probiotic Dairy Product (test), 2-Milk-based non-fermented dairy product(control)
- Where
- France
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Chronic Obstructive Pulmonary Disease
A Real-World Assessment of a COPD Disease Management Support Service (Me & My COPD)
A real world study to determine the effectiveness of a patient support service to aid COPD patients in their self management.
- Trial name
- Me&MyCOPD (NCT02300090)
- Testing
- Test Group, Control Group
- Where
- 23 sites in United Kingdom
- Volunteers
- 161 people
- Sponsor
- AstraZeneca
Microbiome, Metabolic Syndrome
Dietary Fibers Effect on the Gut Microbiota Composition
The randomized double-blinded placebo-controlled multicenter study will be held in parallel groups. During 5 weeks the efficacy of different endpoints as a measure of response to the daily intake of dietary fibers (8 g of either…
- Conditions
- Microbiome, Metabolic Syndrome, Cardiovascular Risk Factor, Inflammation
- Trial name
- NCT04114513
- Testing
- Maltodextrin, Inulin, Pectin
- Where
- Russia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Atlas Biomed
Urinary Bladder Overactive, Overactive Bladder
A Multinational Study Comparing the Long-term Efficacy and Safety of Two Medicines, Solifenacin Succinate and Mirabegron Taken Together, or Separately, in Subjects With Symptoms of Overactive Bladder
The purpose of this study was to examine how well the combination of two medicines (solifenacin succinate and mirabegron) worked compared to each medicine alone in the treatment of bladder problems, and how safe they were for…
- Conditions
- Urinary Bladder Overactive, Overactive Bladder, Urgency Incontinence, Urinary Bladder Diseases\Urologic Diseases
- Trial name
- SYNERGY II (NCT02045862)
- Testing
- Solifenacin succinate, Mirabegron
- Where
- 251 sites in United States, Australia and 30 more
- Volunteers
- 1,829 people
- Sponsor
- Astellas Pharma Europe B.V.
Self-care, Compassion Satisfaction
Effect of Self-care Skill Education on the Compassionate Satisfaction and Compassionate Fatigue Among Clinical Nurses Clinical Nurses at HMC
The health of our nurses is perhaps the most important consideration for delivering excellent patient care. The passionate approach of nurses can lead to a lot of fatigue and stress among nurses.
- Conditions
- Self-care, Compassion Satisfaction, Compassion Fatigue, Educational Intervention
- Trial name
- NCT05983497
- Testing
- Self-Care Skill Educational Intervention
- Where
- Qatar
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Diabetes, Diabetes Mellitus, Type 2
A Study of the Effectiveness of Xultophy® (Insulin Degludec/Liraglutide) in an Adult Real-world Population With Type 2 Diabetes Mellitus
This study is conducted in Europe. The aim of the study is to investigate the effectiveness of Xultophy® (insulin degludec/liraglutide) in an adult real-world population with type 2 diabetes mellitus.
- Trial name
- NCT02754817
- Testing
- insulin degludec/liraglutide
- Where
- 5 sites in Austria, Germany and 3 more
- Volunteers
- 611 people
- Sponsor
- Novo Nordisk A/S
Presbyopia
Safety & Efficacy of the Laser Scleral Microporation Procedure (Philippines)
A minimally invasive procedure for treating presbyopia is being evaluated to determine if there is improvement in near and intermediate vision after treatment.
- Trial name
- NCT04151550
- Testing
- Bilateral Laser Scleral Microporation procedure
- Where
- Philippines
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ACE Vision Group, Inc.
Cervical Intraepithelial Neoplasia
A Post Marketing Surveillance (PMS) Study to Monitor the Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Female Chinese Subjects
The purpose of this prospective, multi-centre, PMS cohort study was to monitor the safety of Cervarix, which is the first HPV vaccine licensed for use in China, to help prevent cervical cancer caused by HPV types 16 and 18.
- Trial name
- NCT03438006
- Testing
- Safety data collection (following routine vaccination)
- Where
- 7 sites in China
- Volunteers
- 3,016 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Heart Transplant Rejection
Molecular Evidence of Rejection Intervention Trial
MERIT is a double-blind, multi-center, placebo-controlled, randomized clinical trial. Heart transplant recipients with dual-positive GEP/dd-cfDNA assays with a corresponding negative biopsy between 2 months and 2 years…
- Trial name
- MERIT (NCT07905599)
- Testing
- Prednisone
- Volunteers
- 200 people
- Sponsor
- CareDx
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