Clinical trials: Intervention Group, completed
- Drug or intervention Intervention Group
- Status Completed
- Funder type Industry (pharma, biotech, devices)
Anterior Ischemic Optic Neuropathy, Ischemic Optic Neuropathy
Epidemiology Study of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
The objectives of this study were to: (1) evaluate the natural history of non-arteritic anterior ischemic optic neuropathy (NAION); (2) estimate the population incidence of NAION; and (3) identify potential risk factors for NAION.
- Trial name
- NCT01260324
- Testing
- No intervention given in this observational study
- Volunteers
- 21,283 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Oral Mucositis
A Comparative Investigation of Standard Of Care (SOC) and Episil® in Combination Versus SOC Alone on Oral Mucositis
To compare the performance of standard of care (SOC) + episil® versus SOC alone on oral mucositis in patients receiving conditioning treatment for hematopoietic stem cell transplantation (HSCT).
- Trial name
- episil(R) (NCT01684566)
- Testing
- episil(R), Oral hygiene procedures
- Where
- 12 sites in Germany, Israel and 2 more
- Volunteers
- 116 people
- Sponsor
- Camurus AB
Critically Ill Mechanically Ventilated Subjects
The DIVINE Study: DIetary Management of Glucose VarIability iN thE ICU
To compare the nutritional effect on blood glucose of two commercially available enteral diets in overweight or obese patients in the Intensive Care Unit.
- Trial name
- NCT02337556
- Testing
- Peptamen Bariatric, Replete
- Where
- 7 sites in United States, Canada
- Volunteers
- 106 people
- Sponsor
- Société des Produits Nestlé (SPN)
Quality of Life
An Exploratory Investigation of Dietary Supplementation and Its Effect
The primary objective of this study is to understand if the test product (HUM supplement) improve symptoms experienced.
- Trial name
- NCT05037877
- Testing
- HUM supplement
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- HUM Nutrition, Inc.
Alzheimer's Disease
A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease
The purpose of this study is to evaluate the changes in the cognitive, functional, behavioral and global domains based on the different applicable psychometric batteries and scales.
- Trial name
- AMBAR (NCT01561053)
- Testing
- Albumin 5%, Albumin 20%, Immunoglobulin
- Where
- 40 sites in United States, Spain
- Volunteers
- 347 people
- Sponsor
- Instituto Grifols, S.A.
Substance Use Disorders, Treatment Adherence and Compliance
RAE (Realize, Analyze, Engage)
The proposed study will evaluate the detection of digital biomarkers of stress, and drug craving in a population of individuals undergoing treatment for substance use disorder
- Trial name
- NCT05227339
- Testing
- RAE
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- ContinueYou, LLC
Increase Intake of Vegetables or Tomatoes, Health
Feasibility Study to Increase Vegetable Consumption
The objective of this study is to determine if differences exist in the total vegetable intake of groups that eat either tomato products versus raw vegetable product.
- Trial name
- VEG1 (NCT02287441)
- Testing
- Tomato, Raw
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
IV Dislodgement
A Feasibility Study Evaluating the Use of SafeBreak Vascular in the Geriatric Trauma Population
SafeBreak Vascular is a medical device indicated for fluid flow control during the administration of IV fluids/medication to the patient's vascular system and to aid in the prevention of unintended disruption and dislodgment of…
- Trial name
- NCT03505957
- Testing
- SafeBreak Vascular
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lineus Medical
Sleep
A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity
This study will evaluate the efficacy of Asutra's 'Dream the night away' nighttime lotion with melatonin and magnesium on sleep health in terms of quantity, quality, ease of falling asleep or falling back asleep after waking in…
- Trial name
- NCT06146712
- Testing
- Asutra's 'Dream the night away' nighttime lotion
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Asutra
Wounds and Injuries
Tissue Perfusion and Blood Flow Monitoring Technology
The purpose of this study is to investigate the safety and efficacy of an optical device designed and developed to quantitatively monitor blood flow velocity of wound sites.
- Trial name
- WoundImager (NCT01139567)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- CW Optics, Inc.
Peptic Ulcer Hemorrhage
China Survey of Peptic Ulcer Bleeding
This will be a multicenter prospective observational study carried out in China. The investigators will collect data in a pre-specified Case Report Form.
- Trial name
- PUB (NCT01241266)
- Where
- 31 sites in China
- Volunteers
- 1,044 people
- Sponsor
- AstraZeneca
Dementia, Vascular, Alzheimer Disease
LEAD IT! An App to Enable Persons With Early Stage Dementia to Lead Group Activities for Their Peers
The proposed Phase 2 project will involve the further development and evaluation of LEAD IT!, which is a tablet-based app designed to enable persons with dementia to lead activities for their peers (i.e., other persons with…
- Conditions
- Dementia, Vascular, Alzheimer Disease, Dementia, Mixed
- Trial name
- NCT05516342
- Testing
- LEAD IT! Programming
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Hopeful Aging
PTSD
OM and Trauma Study
The primary purpose of this study is to use an unblinded, uncontrolled, 1-month interventional single group pilot study, to assess the possibility of Orgasmic Meditation practice being used as a possible intervention for PTSD.
- Trial name
- OMTP (NCT05577377)
- Testing
- Orgasmic Meditation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Institute of OM Foundation
Antibiotic Side Effect, Probiotics
Effectiveness and Safety of Lactobacillus Acidophilus LA85 in Preventing Antibiotic-Associated Diarrhea
This randomized, placebo-controlled, double-blind clinical trial aims to evaluate the efficacy and safety of probiotics as food supplements in preventing antibiotic-associated diarrhea.
- Conditions
- Antibiotic Side Effect, Probiotics, Diarrhea
- Trial name
- NCT05974657
- Testing
- Probiotic Lactobacillus acidophilus LA85
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Wecare Probiotics Co., Ltd.
Lithiasis, Urinary
Study of the Effects of the Consumption of Different Products Cocoa Derivatives at the Risk of Crystallization of Uric Acid in Urine of Volunteers.
The present study aims to assess the effectiveness of theobromine, -product present in high proportion in the cacao-, to prevent the development of uric acid kidney stones.
- Trial name
- NCT03512600
- Testing
- Intervention 0, Intervention 1, Intervention 2
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Devicare S.L.
Atrial Fibrillation
aMAZE Trial Continued Access Protocol
aMAZE CAP is an extension to the current aMAZE Trial investigation (IDEG150107/NCT02517397/Protocol Appendix 16) in the form of a nested, non-randomized registry, to allow ongoing treatment of subjects and the collection of…
- Trial name
- aMAZE CAP (NCT04468334)
- Testing
- LARIAT + PVI
- Where
- 25 sites in United States
- Volunteers
- 82 people
- Sponsor
- AtriCure, Inc.
MacTel (Macular Telangiectasia) Type 2
Extension Study of NT-501 Ciliary Neurotrophic Factor (CNTF) Implant for Macular Telangiectasia (MacTel)
This was a prospective, multicenter, single-masked, sham-controlled extension study designed to provide long-term safety and efficacy follow-up data for subjects with MacTel who had NT-501 implanted intraocularly and/or underwent…
- Trial name
- NCT03071965
- Testing
- Ciliary neurotrophic factor (CNTF), Surgery
- Where
- 11 sites in United States, Australia
- Volunteers
- 70 people
- Sponsor
- Neurotech Pharmaceuticals
Human Papillomavirus Virus, HPV
Web App Technology for Boys and Parents: Improving HPV Vaccine Uptake
The uptake of vaccines for Human Papillomavirus (HPV) in the U.S. is far below recommended levels, particularly for adolescent boys and especially among minority families.
- Trial name
- NCT03000998
- Testing
- Web App Intervention Group, Usual Customary Care Group
- Where
- 3 sites in United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Coronary Artery Disease
BIOFLOW-INDIA Safety and Clinical PerFormance of the Drug Eluting ORSIRO Stent in Single de Novo Coronary Artery Lesions
The objective of this clinical investigation is to assess the safety and clinical performance of the Orsiro Limus Eluting Stent System in Indian subjects with single de-novo coronary artery lesions.
- Trial name
- NCT01426139
- Testing
- Percutaneous Coronary Intervention Biotronik Orsiro DES
- Where
- 4 sites in India
- Volunteers
- 120 people
- Sponsor
- Biotronik AG
Streptococcus Agalactiae
Feasibility Study for Identifying Anti Capsular Antibody Protection Against Invasive Group B Streptococcus (GBS) Disease in Newborns of 0-6 Days Age (Early Onset Disease [EOD]) as Well as Among Infants of 7-90 Days Age (Late Onset Disease [LOD])
The purpose of this study is to evaluate antibody levels against Group B streptococcus in mothers and the risk of developing invasive Group B streptococcus disease in newborns of less than 6 days age as well as infants of age…
- Trial name
- NCT01888471
- Testing
- Blood sample, Vaginal swab sample
- Where
- South Africa
- Volunteers
- 3,033 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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