Clinical trials: Lidocaine
Healthy Volunteer
Study to Compare Active Tymbion Iontophoresis to Sham Tymbion Iontophoresis for Anesthesia of the Tympanic Membrane
A prospective, multicenter study to determine if active Tymbion iontophoresis is superior to sham Tymbion iontophoresis in providing anesthesia to the tympanic membrane (TM).
- Trial name
- ADEPT (NCT03119181)
- Testing
- Tymbion Lidocaine/epinephrine solution, Device: Iontophoresis System (IPS) with Drug: Tymbion lidocaine/epinephrine solution
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tusker Medical
Opioid Use, Arthropathy of Knee
RelieVRx for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use
This is a single-center, prospective, randomized, controlled study of the appliedVR RelieVRx headset in subjects undergoing Total Knee Arthroplasty (TKA).
- Conditions
- Opioid Use, Arthropathy of Knee, Pain, Postoperative
- Trial name
- NCT04010266
- Testing
- RelieVRx headset, multi-modality pain management
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- AppliedVR Inc.
Periodontal Disease
Pediatric Study to Access Pharmacokinetics and Safety of Oraqix Gel
To establish Oraqix is safe when used on adolescent volunteers.
- Trial name
- NCT01591616
- Testing
- lidocaine and prilocaine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Lip Filler Injections
Safety and Efficacy Study of Lip Injections With Emervel Lips Lidocaine and Juvéderm Volbella With Lidocaine
A 12-month, randomised, evaluator-blinded, comparative, multicentre study of the safety and efficacy of lip injections with Emervel Lips Lidocaine and Juvéderm Volbella with Lidocaine.
- Trial name
- NCT01916278
- Testing
- Emervel Lips Lidocaine, Juvéderma Volbella with Lidocaine
- Where
- 3 sites in Germany, Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Galderma R&D
Acute Tendonitis, Bursitis
MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the Shoulder
A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the…
- Trial name
- NCT01161615
- Testing
- MRX-7EAT
- Where
- 35 sites in United States
- Volunteers
- 350 people
- Sponsor
- MEDRx USA, Inc.
Lip Augmentation
A Study to Evaluate the Effectiveness of Juvéderm® VOLIFT™ With Lidocaine for Lip Augmentation
This is an open-label, multi-center, study where eligible participants will undergo treatment with Juvéderm® VOLIFT™ with Lidocaine injected into the lips for lip augmentation.
- Trial name
- LIPS (NCT03796728)
- Testing
- Juvéderm® VOLIFT™ with Lidocaine
- Where
- 4 sites in Portugal, United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allergan
Postherpetic Neuralgia
Study of NGX-4010 With the Use of Open Label Lidocaine (2.5%)/Prilocaine (2.5%) Cream for the Treatment of Postherpetic Neuralgia (PHN)
This study is an open-label multi-center to evaluate the tolerability of treatment with NGX-4010 use with pre-patch topical application of a topical anesthetic cream. This is an open-label study.
- Trial name
- NCT00916942
- Testing
- capsaicin 8%, Lidocaine (2.5%)/Prilocaine (2.5%) Cream
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- NeurogesX
Soft Tissue Approximation, Elevation of Subdermis
Study To Evaluate The Safety And Efficacy Of The MyEllevate® Procedure
The intended purpose of the MyEllevate® procedure used in this study is to assess the safety and efficacy of the procedure for soft tissue approximation and elevation of sub dermis and underlying muscle of the submentum \&…
- Conditions
- Soft Tissue Approximation, Elevation of Subdermis, Elevation of Underlying Muscle
- Trial name
- NCT05590039
- Testing
- MyEllevate Procedure
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Cynosure, Inc.
Acute Non-specific Low Back Pain
Milgamma® and Milgamma® Compositum Step-therapy in Patients With Acute Non-specific Low Back Pain Receiving Modern NSAID
The purpose of this study is to assess the effectiveness and safety of add-on Milgamma®/ Milgamma® compositum step-therapy in patients with acute non-specific low back pain receiving modern NSAIDs in routine medical practice.
- Trial name
- NCT03892707
- Testing
- Exposure of interest (within routine clinical practice):Vitamin B complexes Milgamma® and Milgamma® compositum
- Where
- 21 sites in Russia
- Volunteers
- 500 people
- Sponsor
- Woerwag Pharma LLC
Any Ear Nose or Throat Conditions, With Identified Need for a Diagnostic Procedure or Surgery on or Through the Mucous Membranes of the Nasal Cavities
Topical Application of Cocaine HCl 4%, or 10%, or Placebo Solution in Local (Topical) Anesthesia
Randomized, prospective, multi-center, double blind placebo-controlled parallel group study of a Placebo Topical Solution versus Cocaine HCl 4% Topical Solution for safety and efficacy, and Cocaine HCl 4% and 10% Topical Solution…
- Trial name
- NCT02500836
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- United States
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Contour
Sequential Treatment With BELKYRA® Then Juvéderm® VOLUMA™ With Lidocaine for Overall Improvement in Jawline Contour
This study has been designed to evaluate the safety and effectiveness of sequential treatment with BELKYRA® (for the treatment of convexity and fullness associated with submental fat) and VOLUMA™ (to restore volume along the…
- Trial name
- JAWLINE (NCT03425253)
- Testing
- BELKYRA®, Juvéderm® VOLUMA™ with Lidocaine
- Where
- 3 sites in Australia
- Volunteers
- 58 people
- Sponsor
- Allergan
Dental Implants, Ceramic Implant
Zirconia Implants: Practice-based Evidence
This study is a prospective case series clinical study to examine the effectiveness of Ceramic dental implants manufactured by Swiss Dental Solutions (SDS).
- Trial name
- SDS (NCT06314425)
- Testing
- Immediate dental implants placements on fresh sockets after tooth extraction
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Swiss Dental Solutions
Nasolabial Folds
Evaluation of Pain With Radiesse® With Lidocaine for Nasolabial Folds
To assess pain during nasolabial fold treatment using Radiesse® Injectable Dermal Filler with lidocaine
- Trial name
- NCT01069354
- Testing
- Radiesse® Injectable Dermal Filler with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Where
- 2 sites in Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Localised Prostate Cancer
Microwave Intervention Under Local Anesthesia
This study aims to evaluate the feasibility of performing a focal Targeted Microwave Ablation (TMA) procedure using Koelis TMA® under local anesthesia in patient with localized prostate cancer.
- Trial name
- MILA (NCT07412275)
- Testing
- Local Anesthesia (lidocaine hydrochloride)
- Where
- 2 sites in Belgium, France
- Volunteers
- 20 people
- Sponsor
- Koelis
Correction of Nasolabial Folds
Post Market Study Evaluating Princess Filler Lidocaine for the Correction of Nasolabial Folds
In this study, eligible subjects with moderate to severe nasolabial folds will be treated with Princess® FILLER Lidocaine and will return for follow-up assessments 2, 4, 24 and 36 weeks after the treatment.
- Trial name
- FINO (NCT03611491)
- Testing
- Princess FILLER Lidocaine
- Where
- 2 sites in Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Premature Ejaculation
A Safety and Tolerability Study of Administration of PSD502
A Phase I, Single-Centre, Double-Blind, Randomised, Placebo-Controlled, Parallel Group, Pharmacokinetic and Safety Study to Evaluate Systemic Exposure and Local Vaginal Exposure to Lidocaine and Prilocaine and the Metabolites 2,6…
- Trial name
- NCT01183208
- Testing
- Intervention A, Intervention B, Intervention C
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Pain, Nosalabial Folds Correction
The Safety and Efficacy of Using HYADERMIS LA for Wrinkle Correction
The study is a double-blind, randomized, within-subject controlled, 2-armed, single-centre study sponsored by SciVision Biotech Inc. and approved by Yuan's General Hospital Institutional Review Board.
- Trial name
- NCT02128204
- Testing
- lidocaine contained hyaluronate facial dermal filler, hyaluronate facial dermal filler
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Moderate to Severe Nasolabial Folds
Saypha® Volume LIdocaine in Nasolabial Folds
Comparison of saypha Volume Lidocaine from 2 different manufacturing locations in correcting moderate to sever nasolabial folds
- Trial name
- SAVINO (NCT04883632)
- Testing
- Saypha Volume Lidocaine
- Where
- 3 sites in Austria
- Volunteers
- 110 people
- Sponsor
- Croma-Pharma GmbH
Healthy Volunteers
Performance and Safety of Restylane Lidocaine for Treatment of Depressed Facial Acne Scars
The purpose of this study is to evaluate performance and safety of Restylane Lidocaine for treatment of depressed facial acne scars
- Trial name
- NCT03127384
- Testing
- Restylane Lidocaine, No-treatment control
- Where
- 2 sites in Germany
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Pain
Safety Study of S-Caine Peel (Skin Numbing Cream) Before a Painful Dermatologic Procedure in Adults
The purpose of this study is to evaluate the safety of one treatment of S-Caine™ Peel (skin numbing cream) applied on healthy skin before a painful dermatologic procedure in adults.
- Trial name
- NCT00107835
- Testing
- S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)
- Where
- 5 sites in United States
- Volunteers
- 408 people
- Sponsor
- ZARS Pharma Inc.