Clinical trials: Lidocaine
Safety
A Study to Evaluate the Safety Following Injection of GP0045 Compared to Restylane Lyft Lidocaine
This is a study to assess the safety of GP0045 compared to Restylane Lyft Lidocaine. There is a 12-week follow-up period. AEs will be recorded throughout the study.
- Trial name
- NCT03133325
- Testing
- GP0045, Restylane Lyft Lidocaine
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Facial Tissue Augmentation
A Study of Treatment Preference During Cheek Contouring Comparing Restylane® SubQ With and Without the Addition of Lidocaine Hydrochloride
The objectives of this study are to evaluate the pain-relieving effect and safety of adding lidocaine hydrochloride to Restylane SubQ and to evaluate the esthetic improvement obtained.
- Trial name
- NCT01431755
- Testing
- Restylane SubQ, Restylane SubQ Lidocaine
- Where
- 3 sites in Sweden
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Abnormal Lip
Study to Evaluate the Effectiveness, Safety and Long Term Safety of Saypha® FILLER Lidocaine for Lip Augmentation
This is a prospective, open-label, multicentre, randomized study conducted to evaluate the effectiveness, safety and long-term safety of Saypha® FILLER Lidocaine for lip augmentation.
- Trial name
- SayLip (NCT04917588)
- Testing
- Saypha® FILLER Lidocaine (HQ), Saypha® FILLER Lidocaine (C1)
- Where
- 3 sites in Austria
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Moderate to Severe Nasolabial Folds
Post-Market Study of JUVÉDERM VOLIFT™ With Lidocaine for the Correction of Nasolabial Folds
A prospective, open-label, multi-center, observational, post-market study evaluating JUVÉDERM VOLIFT™ for the correction of moderate to severe nasolabial folds
- Trial name
- NCT01680497
- Testing
- Crosslinked hyaluronic acid dermal filler
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Allergan
Healthy
Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% Under Conditions of Heat and Exercise
The objectives of this study are to evaluate the pharmacokinetic and adhesion performance of ZTlido (lidocaine topical system) 1.8% during physical exercise, application of heat, and under normal conditions.
- Trial name
- NCT04150536
- Testing
- Lidocaine topical system 1.8%
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Scilex Pharmaceuticals, Inc.
Wrinkles Such as Nasolabial Folds
Evaluate the Efficacy and Safety of Lidocaine-Containing Hyaluronic Acid Filler in the Treatment of Nasolabial Folds.
The purpose of this study is to evaluate the efficacy and safety of PavéDerm J-fill soft dermal filler vs. Restylane® Lyft lidocaine in the treatment of moderate to severe nasolabial folds.
- Trial name
- NCT05040594
- Testing
- PavéDerm J-Fill Soft Dermal Filler, Restylane® Lyft Lidocaine
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Lip Volume Enhancement
Safety and Effectiveness of Juvéderm® Volbella With Lidocaine Versus Restylane-L® for Lip Volume Enhancement
The purpose of this study is evaluate lip fullness 3 months following treatment with Juvéderm® Volbella with Lidocaine or Restylane-L®
- Trial name
- NCT01579305
- Testing
- Juvéderm® Volbella with Lidocaine, Restylane-L®
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Allergan Medical
Urinary Bladder, Overactive
Efficacy and Safety of GSK1358820 in Subjects With Overactive Bladder
GSK1358820 is a botulinum neurotoxin A complex that has been approved for the treatment of overactive bladder (OAB) in several countries, however, it has not been approved for OAB treatment in Japan.
- Trial name
- NCT02820844
- Testing
- GSK1358820, Antibiotic therapy, Bladder diary
- Where
- 48 sites in Japan
- Volunteers
- 250 people
- Sponsor
- GlaxoSmithKline
Obesity, Morbid
The Lowering Weight in Severe Obesity by Embolization of the Gastric Artery Trial
To evaluate the efficacy and safety of the Endobar gastric embolization system for the treatment of obesity before continuing to a larger Pivotal Trial.
- Trial name
- LOSEIT (NCT03185949)
- Testing
- Endobar Infusion Catheter System, Behavioral therapy
- Where
- Czechia
- Volunteers
- 44 people
- Sponsor
- Endobar Solutions LLC
Skin Wrinkling
Emervel Classic Lidocaine Versus Juvederm® Ultra in Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of this study is to compare the effectiveness and safety of Emervel Classic Lidocaine versus Juvederm® Ultra in the treatment of moderate to severe facial wrinkles and folds.
- Trial name
- NCT01205048
- Testing
- Emervel Classic Lidocaine, Juvederm® Ultra
- Where
- 12 sites in United States
- Volunteers
- 171 people
- Sponsor
- Galderma R&D
Dermal Filler, Hyaluronic Acid
The Evaluation of the Safety and Effectiveness of a Novel Gel-type Sodium Hyaluronate for the Correction of Aging Mid-face
This study is to evaluate the safety and effectiveness for the correction of aging mid-face of treatment group compared with the negative control group.
- Conditions
- Dermal Filler, Hyaluronic Acid, Lidocaine, Aging Mid-Face
- Trial name
- NCT04599335
- Testing
- 2% HA
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Pain, Chronic Pain
Lidocaine 5% Medicated Plaster in Chronic Neuropathic Postoperative Pain
The purpose of this trial is to investigate the efficacy and safety of lidocaine 5% medicated plaster in localized chronic post-operative neuropathic pain in comparison to placebo plaster.
- Conditions
- Pain, Chronic Pain, Neuropathic Pain, Postoperative Pain
- Trial name
- NCT01155986
- Testing
- Lidocaine 5% medicated plaster
- Where
- 22 sites in France
- Volunteers
- 74 people
- Sponsor
- Grünenthal GmbH
Osteoarthritis of the Knee
Lidocaine Patch Versus Celecoxib in Pain From Osteoarthritis of the Knee
Patients with unilateral or bilateral osteoarthritis of the knee participated in a Phase IV clinical trial to assess the efficacy of Lidoderm compared with celecoxib 200mg in treating pain from osteoarthritis of the knee.
- Trial name
- NCT00904605
- Testing
- Lidoderm, Celecoxib
- Where
- 20 sites in United States
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Wrinkle, Nasolabial Fold
RHA® 4 NLF Cannula
This is a randomized, controlled, single-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA®4 injected in NLFs with a cannula is non-inferior to RHA®4 injected in NLFs with a sharp…
- Conditions
- Wrinkle, Nasolabial Fold, Aging
- Trial name
- NCT04754646
- Testing
- Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Pain
Pharmacokinetic Study of Synera™ in Neonates and Infants
This study will measure the amount of lidocaine and tetracaine in the blood after a 30 minute application of Synera.
- Trial name
- NCT00747669
- Testing
- lidocaine 70mg and tetracaine 70mg topical patch
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- ZARS Pharma Inc.
Electroencephalographic Neonatal Seizures
A Study to Test the Pharmacokinetics, Efficacy, and Safety of Brivaracetam in Newborns With Repeated Electroencephalographic Seizures
The purpose of the study is to evaluate the pharmacokinetics (PK) of brivaracetam (BRV) in neonates who have seizures that are not adequately controlled with previous antiepileptic drug (AED) treatment, and to identify the…
- Trial name
- NCT03325439
- Testing
- Brivaracetam (BRV) intravenous (iv), Brivaracetam (BRV) oral
- Where
- 12 sites in Belgium, Czechia and 5 more
- Volunteers
- 9 people
- Sponsor
- UCB Biopharma SRL
Aging
Subjects' Satisfaction on Pan Facial Aesthetic Enhancement After Treatment With Azzalure® and the Restylane® Range
The aim of this study is to assess subjects' satisfaction linked to the pan facial management of rejuvenation with injections of Azzalure® and Restylane® fillers. This will be an open, multi-centre study.
- Trial name
- FIRST (NCT01529203)
- Testing
- Botulinum Toxin Type A (Azzalure), Restylane ranges
- Where
- 5 sites in France, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Galderma R&D
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofrequency Microneedling for Facial Rejuvenation
This randomized, single-center, double-blinded, controlled, clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after radiofrequency microneedling and…
- Trial name
- NCT06157853
- Testing
- Radiofrequency Microneedling, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Laxity
Feasibility Study: Evaluate the Effectiveness of Using a Topical Anesthetic Prior to Ultherapy™ Treatment
This study will evaluate the efficacy of a lidocaine topical anesthetic (numbing cream) for reducing discomfort associated with Ultherapy™ treatment.
- Trial name
- NCT01708447
- Testing
- L.M.X.4.® cream, Ulthera System Treatment
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Nasolabial FOLD
To Evaluate the Efficacy and Safety of Injection With HARA as Compared to Restylane® Lidocaine in Temporary Correction of Nasolabial Folds
Investigational Device : HARA (Hyaluronic Acid Filler) Title : A Single center, Randomized, Subject \& Evaluator-blind, Matched pairs, Active-controlled design Pivotal study to Evaluate the Efficacy and Safety of Injection with…
- Trial name
- NCT04224649
- Testing
- HARA Filler(Hyaluronic acid Filler), Restylane® Lidocaine
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Huons Co., Ltd.