Clinical trials: Pregabalin
Idiopathic Restless Legs Syndrome
Long Term Study Of Pregabalin In Idiopathic Restless Legs Syndrome Patients
This purpose of this study is to investigate the efficacy and tolerability of pregabalin in treating idiopathic RLS patients for up to 12 months.
- Trial name
- RLS (NCT00806026)
- Testing
- pramipexol, Pregabalin
- Where
- 110 sites in United States, Austria and 7 more
- Volunteers
- 731 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain Associated With Fibromyalgia
Special Investigation of Pregabalin for Fibromyalgia (Regulatory Post Marketing Commitment Plan)
To collect the efficacy and safety information of Pregabalin on Fibromyalgia patients related to their appropriate use in daily practice.
- Trial name
- NCT01773993
- Testing
- Pregabalin
- Volunteers
- 534 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Restless Legs Syndrome
Lyrica Dose Response Study With Restless Legs Syndrome (RLS) Patients
To test the effectiveness and tolerability of Lyrica at various dose levels in RLS patients
- Trial name
- NCT00676403
- Testing
- Pregabalin
- Where
- 25 sites in United States, Austria and 2 more
- Volunteers
- 137 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Generalized Anxiety Disorder
Efficacy and Safety of Pregabalin vs Placebo for Generalized Anxiety Disorder (GAD) Symptoms in Subjects Discontinuing Benzodiazepine Treatment and Remaining 6 Weeks on Study Medication, Free From Benzodiazepine Use.
GAD subjects maintained on a stable dose of alprazolam for at least four weeks who meet eligibility criteria will be randomized to receive pregabalin vs matching placebo while simultaneously tapering off of alprazolam over 6…
- Trial name
- GAD (NCT00368745)
- Testing
- Pregabalin
- Where
- 21 sites in Costa Rica, Czechia and 5 more
- Volunteers
- 108 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Postherpetic Neuralgia
Efficacy and Safety of Pregabalin Sustained Release Tablet for Postherpetic Neuralgia
The purpose of this study is to evaluate the Efficacy and safety of pregabalin sustained release tablet versus placebo for postherpetic neuralgia.
- Trial name
- EASOPSRTFP (NCT02868801)
- Testing
- Pregabalin SR tablet 165mg/day, Pregabalin SR tablet 330mg/day, Pregabalin SR tablet 660mg/day
- Where
- 27 sites in China
- Volunteers
- 280 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
A 2-part Trial to Learn More About How BAY1817080 Works, How Safe it is, and What the Right Dose is for Participants With Diabetic Neuropathic Pain
People suffering from diabetes often have high blood sugar levels. Over time this can affect many organs including the nerves in hands and feet and can cause a nerve pain called diabetic neuropathic pain (DNP).
- Trial name
- NCT04641273
- Testing
- BAY1817080, Pregabalin
- Where
- 42 sites in Czechia, Denmark and 8 more
- Volunteers
- 154 people
- Sponsor
- Bayer
Healthy Participants
A Trial Investigating the Pain-relieving Properties of Lu AG06474 in Healthy Adult Participants
The main goal of this trial is to learn about the effect of Lu AG06474 on a battery of Evoked Pain Tests when a single dose is given to healthy adult participants.
- Trial name
- NCT06077786
- Testing
- Lu AG06474, Ibuprofen, Pregabalin
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Pain
Evaluate Long-Term Safety and Efficacy of Pregabalin in Patients With Chronic Neuropathic Pain.
Evaluate long-term safety and efficacy of pregabalin in patients with chronic neuropathic pain.
- Trial name
- NCT00141362
- Testing
- Pregabalin
- Volunteers
- 325 people
- Sponsor
- Pfizer
Osteoarthritis, Postoperative Pain
Efficacy And Safety Of Pregabalin For Pain Following Total Knee Replacement
Pregabalin added to the standard of care with dosing starting preoperatively and continuing for up to 6 weeks post surgery will decrease the intensity of post-operative pain following total knee replacement.
- Trial name
- NCT00442546
- Testing
- pregabalin
- Where
- 27 sites in United States
- Volunteers
- 307 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain
Pharmacokinetics Study of XG005 Capsule
This was a Phase 1, single-center, randomized, placebo-controlled, 2-period, ascending single-dose study assessing the PK, safety, and tolerability of single ascending doses of XG005 (Period 1) and the naproxen and pregabalin…
- Trial name
- NCT04499209
- Testing
- XG005, Combination of Naproxen and Pregabalin
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Xgene Pharmaceutical Group
Seizures
Pregabalin In Partial Seizures Extension Study
To evaluate long-term efficacy and safety of pregabalin (150 to 600mg/day) as adjunctive treatment in patients with partial seizures.
- Trial name
- PREPS EXT (NCT00143130)
- Testing
- Pregabalin
- Where
- 47 sites in Belgium, Finland and 4 more
- Volunteers
- 227 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of Two Controlled Release Pregabalin Tablets As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule In Healthy Volunteers
The purpose of this study is to 1) evaluate the extent of absorption of multiple doses of two pregabalin controlled release tablets as compared to multiple doses of the pregabalin immediate release capsule, 2) evaluate the…
- Trial name
- NCT01220219
- Testing
- Pregabalin controlled release, 82.5 mg, Pregabalin controlled release, 165 mg, Pregabalin immediate release, 75mg
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Partial Seizures
Pregabalin In Partial Seizures (PREPS): An Open-Label, Multicenter Add On Therapy Trial
The purpose of this study is to assess the clinical improvement by partial seizures reduction, safety and tolerability of subjects having partial epilepsy related to the adjunction of pregabalin BID (75 to 300mg day titration…
- Trial name
- PREPS MEXICO (NCT00407797)
- Testing
- Pregabalin
- Where
- 8 sites in Mexico
- Volunteers
- 136 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy
Study for Comparing The Pharmacokinetics of A Pregabalin Controlled Release Tablet 300mg With Immediate Release Formulation and to Assess the Effect of High Fat Diet in Healthy Male Subjects
The purpose of this study is to: 1. Compare the pharmacokinetics profiles of pregabalin sustained release tablet (300mg) to immediate release capsule(150mg * 2). 2.
- Trial name
- NCT02103686
- Testing
- Lyrica, Experimental drug, High fat meal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Diabetic Peripheral Neuropathic Pain
To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain
Investigate the efficacy and safety of HSK16149 capsules in Chinese diabetic peripheral neuropathic pain (DPNP) following 13 weeks treatment in comparison to placebo.
- Trial name
- NCT04647773
- Testing
- HSK16149 20mg BID, HSK16149 40mg BID, HSK16149 60mg BID
- Where
- China
- Volunteers
- 687 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Peripheral Neuropathic Pain
Clinical Trial of YHD1119 in Patients With Peripheral Neuropathic Pain
A Randomized, Double-blind, Active-Controlled, Multi-center, Phase 3 Trial to Compare the Safety and Efficacy between YHD1119 and Pregabalin in Patients with Peripheral Neuropathic Pain
- Trial name
- NCT02985216
- Testing
- YHD1119, Lyrica
- Where
- South Korea
- Volunteers
- 371 people
- Sponsor
- Yuhan Corporation
Healthy
Assessment of the Analgesic Effects of PF-05089771 and Pregabalin in Healthy Volunteers Using Evoked Pain Endpoints
This study will examine the activity of PF-05089771 and pregabalin, alone and in combination on a panel of evoked pain tests carried out from 0.5 to 10 hours following oral dosing in healthy male subjects
- Trial name
- NCT02349607
- Testing
- PF-05089771 300mg, PF-05089771 300 mg + pregabalin 300 mg, pregabalin 300 mg
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Postherpetic Neuralgia ( PHN )
Pregabalin for Treatment of Patients With Postherpetic Neuralgia (PHN)
To prove pregabalin is effective in relieving pain compared with placebo in subjects with postherpetic neuralgia (PHN).
- Trial name
- NCT01455428
- Testing
- Lyrica (pregabalin)
- Where
- 22 sites in China
- Volunteers
- 223 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain
A Methodology Study Of Brain Imaging Of Pain-Killers In Post-Traumatic Neuropathic Pain Patients
This study is a methodology study designed to discover whether a brain imaging technology is a better way of compare the relative sensitivities of fMRI and subjective psychometric assessments of pain to multiple doses of…
- Trial name
- NCT00610155
- Testing
- Pregabalin, Tramadol SR
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuralgia, Postherpetic, Diabetic Neuropathy
Neuropathic Pain Syndrome Patient Study (MK-0000-072)
The purpose of this study is to determine the best way to conduct clinical trials in patients with neuropathic pain (nerve pain). This study will see if generic pregabalin has any effect on neuropathic pain.
- Conditions
- Neuralgia, Postherpetic, Diabetic Neuropathy, Painful Small-Fiber Neuropathy, Idiopathic Distal Sensory Polyneuropathy
- Trial name
- NCT00570310
- Testing
- Comparator: pregabalin
- Volunteers
- 104 people
- Sponsor
- Merck Sharp & Dohme LLC