Clinical trials: Pregabalin
Acute Pain
Bunionectomy Study (0000-063)
We are interested in whether bunionectomy can be used as a model to study the treatment of acute pain. It has been used to study the effect of Non-Steroidal Anti-inflammatory (NSAIDS) medications (such as ibuprofen) and other…
- Trial name
- NCT00601458
- Testing
- pregabalin, naproxen sodium
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Neuralgia
Non-Interventional Study In Patients With Peripheral Or Central Neuropathic Pain Treated With Lyrica
The purpose of this study is to obtain more data about efficacy and safety of the study drug Lyrica.
- Trial name
- NCT00541476
- Volunteers
- 746 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuropathic Pain
A Study to Assess the Efficacy, Safety and Tolerability of Pregabalin in Patients With Symptoms of Neuropathic Pain
The objective of this study is to evaluate the efficacy, safety and tolerability for pregabalin using a flexible, optimized dose schedule compared to placebo in relieving the symptoms of neuropathic pain.
- Trial name
- NCT00301223
- Testing
- Pregabalin
- Where
- 7 sites in China
- Volunteers
- 309 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain
Pharmacokinetics Study of XG005 Capsule
This was a Phase 1, single-center, randomized, placebo-controlled, 2-period, ascending single-dose study assessing the PK, safety, and tolerability of single ascending doses of XG005 (Period 1) and the naproxen and pregabalin…
- Trial name
- NCT04499209
- Testing
- XG005, Combination of Naproxen and Pregabalin
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Xgene Pharmaceutical Group
Diabetic Neuropathy, Painful; Diabetic Neuropathies
Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability
This is a 2-part study. In Part 1 of the study, subjects will undergo a pain reporting training program in which a painful stimulus will be applied to the subject's hand, and the subjects will be asked to report how painful the…
- Trial name
- NCT01928381
- Testing
- AZD5213 + pregabalin, pregabalin capsules
- Where
- 9 sites in United States
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
Neurologic Claudication in Patients With Lumbar Spinal Stenosis
A Study to Evaluate Efficacy of 『Opast Tablet』for Neurologic Claudication in Patients With Lumbar Spinal Stenosis
This trial is a comparative study of Opast tablet and Rikalin capsule 75mg and Rikalin capsule 75mg in combination with Opast tablet to evaluate improvement effectiveness of Opast tablet on subjective symptoms and neurologic…
- Trial name
- NCT01888536
- Testing
- Limaprost, Pregabalin
- Where
- 7 sites in South Korea
- Volunteers
- 182 people
- Sponsor
- Yungjin Pharm. Co., Ltd.
Painful Diabetic Neuropathy and Post Herpetic Neuralgia
A Study of the Efficacy and Safety of Pregabalin for the Treatment of Diabetic Peripheral Neuropathy or Postherpetic Neuralgia
The purpose of this study is to assess the efficacy and safety of pregabalin for the treatment of diabetic peripheral neuropathy (DPN) or postherpetic neuralgia (PHN)
- Trial name
- NCT00629681
- Testing
- Pregabalin
- Where
- 46 sites in Germany
- Volunteers
- 217 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Diabetic Peripheral Neuropathy
Pregabalin and Alpha-lipoic Acid Combination Versus Each Monotherapy in Patients With Diabetic Peripheral Neuropathy
This study is a randomized, parallel, open-label, multicenter, phase IV clinical trial to assess the efficacy and safety of pregabalin and alpha-lipoic acid combination compared with each monotherapy in patients with diabetic…
- Trial name
- OPTIMUM (NCT04846673)
- Testing
- Pregabalin 150mg + Alpha-lipoic acid 480mg, Pregabalin 150mg, Alpha-Lipoic Acid 480mg
- Where
- 14 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Yuhan Corporation
Healthy
Assessment of the Analgesic Effects of PF-06372865 in Healthy Volunteers Using Evoked Pain Endpoints
This study will examine the activity of 2 different doses of PF-06372865 on a panel of evoked pain tests carried out from 0.5 to 10 hours following oral dosing in healthy male subjects.
- Trial name
- NCT02238717
- Testing
- PF-06372865 (65mg), PF-06372865 (15mg), Pregabalin
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Partial Onset Seizures
A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.
This study is designed to evaluate the effectiveness of 2 doses of pregabalin to reduce seizure frequency as an add on therapy in pediatric subjects 1 month to <4 years of age with refractory partial onset seizures.
- Trial name
- NCT02072824
- Testing
- Pregabalin Dose Level 1, Pregabalin Dose Level 2
- Where
- 72 sites in United States, Belarus and 21 more
- Volunteers
- 175 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Seizure Disorder, Partial
To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures
To evaluate the long-term safety and efficacy of pregabalin in patients with partial seizures.
- Trial name
- NCT00141388
- Testing
- Pregabalin
- Where
- 56 sites in United States, Canada
- Volunteers
- 455 people
- Sponsor
- Pfizer
Postherpetic Neuralgia, Pain
Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)
The primary objective of this study is to evaluate the analgesic efficacy of 2 dose levels of V116517 versus placebo.
- Trial name
- NCT01688947
- Testing
- V116517 50-mg tablets, V116517 30-mg tablets, Pregabalin capsules
- Where
- 28 sites in United States
- Volunteers
- 105 people
- Sponsor
- Purdue Pharma LP
Healthy Male and Female Subjects
Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in U.S. Healthy Participants
The primary goal of this clinical trial is to compare pharmacokinetic characteristics of Y-4 tablets with pregabalin capsules and riluzole tablets in the US healthy adult participants after single oral administration under fasted…
- Trial name
- NCT07618715
- Testing
- Y-4 tablet, Pregabalin capsule, Riluzole tablet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Neurodawn Pharmaceutical Co., Ltd.
Fibromyalgia
Safety and Efficacy Study of Pregabalin in Fibromyalgia
The purpose of this research study of pregabalin and fibromyalgia is to see if 1. pregabalin reduces the pain of fibromyalgia and if this effect lasts for six months and 2.
- Trial name
- NCT00151489
- Testing
- pregabalin
- Where
- 109 sites in United States
- Volunteers
- 1,020 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuropathic Pain
Safety And Efficacy In Long Term Use Of Lyrica (Regulatory Post Marketing Commitment Plan)
The objective of this investigation is to evaluate the safety and efficacy of long term use with Lyrica in medical practice. Also, occurrence of unknown and known adverse drug reactions (ADRs) in subjects treated with Lyrica will…
- Trial name
- RAINBOW-L (NCT01279850)
- Testing
- Pregabalin (Lyrica) capsule
- Volunteers
- 891 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuralgia
A Study to Assess the Safety and Efficacy of 7 Days Treatment With a Novel Analgesic in Subjects With Peripheral Neuropathic Pain
The purpose of this trial is to determine whether a novel analgesic is effective in treating of neuropathic pain caused by herpetic infection, surgery, or trauma.
- Trial name
- NCT01485094
- Testing
- GRT6010, Pregabalin
- Where
- 12 sites in Germany, Hungary and 2 more
- Volunteers
- 114 people
- Sponsor
- Grünenthal GmbH
Spinal Cord Injuries
Study to Determine if a Reduction in Pain Can be Measured in Spinal Cord Injured Patients Using a New Study Design
The study is designed to assess if spinal cord injury patients have reduced pain after taking either pregabalin or placebo in a cross over design.
- Trial name
- NCT00978341
- Testing
- Pregabalin
- Where
- 4 sites in Australia
- Volunteers
- 15 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Generalized Anxiety Disorder
Safety and Efficacy Evaluation Of Pregabalin (Lyrica) With Patients With Generalized Anxiety Disorder
The purpose of this study is to characterize the safety and efficacy in patients with generalized anxiety disorder after short- (3 months) and long-term (6 months) use of Pregabalin (Lyrica).
- Trial name
- NCT00624780
- Testing
- Pregabalin, Lorazepam
- Where
- 57 sites in Argentina, Austria and 14 more
- Volunteers
- 615 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Diabetic Neuropathy, Painful
Study Of Pregabalin (Lyrica) In Patients With Painful Diabetic Peripheral Neuropathy
Patients will be switched from their current medication for painful diabetic peripheral neuropathy to evaluate the safety and efficacy of pregabalin as compared to placebo.
- Trial name
- NCT01057693
- Testing
- pregabalin (Lyrica)
- Where
- 172 sites in United States, Canada and 2 more
- Volunteers
- 633 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain
[S,S]-Reboxetine Add-On Trial
The purpose of this study is to determine the effectiveness of adjunctive treatment of pregabalin with [S,S]-Reboxetine against pregabalin monotherapy in patients with PHN
- Trial name
- NCT00334685
- Testing
- [S,S]-Reboxetine + Pregabalin, Pregabalin
- Where
- 83 sites in United States, Austria and 14 more
- Volunteers
- 136 people
- Sponsor
- Pfizer