Clinical trials: Water
Healthy
Effect of Repeated Doses of BI 1060469 and BI 1021958 on Glomerular Filtration Rate (GFR) in Healthy Volunteers
Main objective is to investigate the measured glomerular filtration rate (mGFR) as assessed by iohexol clearance in healthy male normovolemic subjects after oral administration of single and repeated doses of BI 1060469, and BI…
- Trial name
- NCT02202512
- Testing
- Cimetidine, BI 1060469 high dose, BI 1060469 low dose
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteers
To Evaluate Pharmacokinetics and Safety of Two Different Formulation of Rebamipide in Healthy Volunteers
This is a randomized, open label, multiple dose, crossover study to compare the safety and Pharmacokinetics (PKs) between two rebamipide formulations after multiple oral doses of "rebamipide SR 150 mg" and "rebamipide IR 100 mg"…
- Trial name
- NCT04150172
- Testing
- Rebamipide SR 150mg, Rebamipide IR 100mg
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Healthy
Bioequivalence Study Of Diltiazem In 60 Mg Tablets As Tilazem 60® Made by Pfizer, S.A. De C.V., Versus Angiotrofin® 60 Mg Made by Amstrong Laboratorios De Mexico, S.A. De C.V.
This study will research the existance of actual bioequivalence between Diltiazem in 60 Mg Tablets As Tilazem 60® Made by Pfizer, S.A. DE C.V., Versus Angiotrofin® 60 Mg Made by Amstrong Laboratorios De Mexico, S.A. DE C.V.
- Trial name
- NCT01151345
- Testing
- TILACEM, ANGIOTROFIN
- Where
- Mexico
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Pfizer
Acute Liver Failure, Acute-On-Chronic Liver Failure
F573 for Injection for the Treatment of Liver Injury/Failure
This study was a randomized, double-blind, placebo-controlled PhaseⅡ clinical trial . The primary objective of this study was to evaluate the safety of F573 for injection in patients with liver injury (drug-induced liver injury…
- Trial name
- NCT05689645
- Testing
- F573 for injection, Sterilizing water for injection
- Where
- 10 sites in China
- Volunteers
- 97 people
- Sponsor
- Beijing Continent Pharmaceutical Co, Ltd.
Virus Diseases
Study to Evaluate the Efficacy and Safety of Danirixin Co-administered With Oseltamivir in the Treatment of Adults Hospitalized With Influenza
Danirixin (DNX) is a novel, selective, and reversible antagonist of the C-X-C chemokine receptor (CXCR) 2 and has been shown to decrease neutrophil transmigration and activation to areas of inflammation.
- Trial name
- NCT02927431
- Testing
- Danirixin 15 mg FBE, Danirixin 50 mg FBE, Oseltamivir 75 mg
- Where
- 8 sites in United States, Romania and 2 more
- Volunteers
- 10 people
- Sponsor
- GlaxoSmithKline
Common Wart
A Study of A-101 Topical Solution for the Treatment of Common Warts
Phase 3 Study of A-101 Topical Solution in Subjects with Common Warts
- Trial name
- NCT03691831
- Testing
- Active, Vehicle
- Where
- 24 sites in United States
- Volunteers
- 502 people
- Sponsor
- Aclaris Therapeutics, Inc.
Glycaemic Response, Insulinemic Response
The Effects of D-Fagomine on Glycaemic Response to Sucrose in Men
The aim of this study is to evaluate the effect of D-fagomine on glycaemic response to sucrose in men.
- Trial name
- NCT01528631
- Testing
- D-Fagomine
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Bioglane
Healthy
A Study in Healthy Men to Test How Well Different Doses of BI 3731579 Are Tolerated
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 3731579 in healthy male subjects.
- Trial name
- NCT06429137
- Testing
- BI 3731579
- Where
- Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Embryo Transfer
Dose Escalation Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Epelsiban Administered in Repeat Doses in Healthy Women Volunteers
The current study is designed to assess the safety, tolerability and pharmacokinetics (PK) of additional repeat doses of epelsiban in healthy females, and will be the first dosing experience of repeat dosing at higher doses in…
- Trial name
- NCT02703181
- Testing
- Epelsiban (GSK557296)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tinea Versicolor
A Study Comparing Ketoconazole Shampoo, 2% and Ketoconazole 2% Shampoo (RS) in the Treatment of Tinea Versicolor.
To demonstrate the efficacy, therapeutic equivalence and safety of Ketoconazole Shampoo, 2% (Taro Pharmaceuticals U.S.A., Inc.) and Ketoconazole 2% Shampoo (Reference Standard) in the treatment of tinea versicolor.
- Trial name
- NCT06305637
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Diarrhea
Prevention of Diarrheal Disease Due to Infection With Enterotoxigenic E. Coli (ETEC)
This is a Phase II b, double-blind, randomized, placebo-controlled study in healthy adults (age 18-65 years) to evaluate the safety, immunogenicity, different diagnostic tools and efficacy of ETVAX.
- Trial name
- NCT03729219
- Testing
- E. coli ETVAX
- Where
- Finland
- Volunteers
- 749 people, healthy volunteers welcome
- Sponsor
- Scandinavian Biopharma AB
Acute Dental Pain
Study of P3914 to Evaluate the Safety, Tolerability, Food Effect & Pharmacokinetics in Healthy Male Subjects and Efficacy & Safety of P3914 in Patients With Acute Dental Pain
P3914 a pro-drug of Naproxen, characterized by naproxen (COX inhibiting moiety) linked to a NO moiety is intended for the treatment of pain and inflammation.
- Trial name
- NCT01339156
- Testing
- P3914
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Piramal Enterprises Limited
Menstrual Pain, Premenstrual Syndrome
An Investigation Into the Efficacy of a Botanical Supplement to Provide Period Relief
Women often experience significant pain during their periods which can significantly impact on quality of life. In this study, two products that are used to alleviate period pain will be examined.
- Trial name
- NCT05845970
- Testing
- Pamprin Botanicals, Pamprin Botanicals + Pamprin Menstrual Pain Relief
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Focus Consumer Healthcare
Familial Hypercholesterolemia - Heterozygous
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
This is a pivotal phase III study designed to evaluate safety, tolerability, and efficacy of inclisiran in children (aged 6 to <12 years) with heterozygous familial hypercholesterolemia (HeFH) and elevated low density lipoprotein…
- Trial name
- ORION-20 (NCT06597019)
- Testing
- Inclisiran
- Where
- 66 sites in United States, Argentina and 21 more
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Low Back Pain
Different Dosage Regimens of Methocarbamol/Paracetamol in Acute Non-specific Low Back Pain. MioPain Study
The aim of the study is to evaluate the efficacy and safety of different dosage regimens of the combination methocarbamol/paracetamol in the treatment of patients with acute non-specific Low Back Pain.
- Trial name
- MioPain (NCT05204667)
- Testing
- 380 mg/300 mg comprimidos metocarbamol/paracetamol - 4 times daily, 380 mg/300 mg comprimidos metocarbamol/paracetamol - 6 times daily
- Where
- 3 sites in Italy
- Volunteers
- 172 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Amino Acid Metabolism, Inborn Errors
Ataluren for Nonsense Mutation Methylmalonic Acidemia
Methylmalonic acidemia (MMA) is a rare genetic disorder caused by mutations in the gene for mitochondrial enzyme methylmalonyl-CoA mutase (MCM) or in one of the genes for adenosylcobalamin (AdoCbl).
- Trial name
- NCT01141075
- Testing
- Ataluren
- Where
- 9 sites in Belgium, France and 4 more
- Volunteers
- 11 people
- Sponsor
- PTC Therapeutics
Cystic Fibrosis
To Assess the Safety, Tolerability and Pharmacokinetics of AZD5634 Following Inhaled and Intravenous (IV)Dose Administration
This is a Phase 1, first-in-human (FIH) single ascending dose study being conducted to better understand the safety, tolerability and pharmacokinetics of AZD5634 in healthy subjects
- Trial name
- NCT02679729
- Testing
- AZD5634 for inhalation, AZD5634 for infusion
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Human Immunodeficiency Virus (HIV) Infection
Bioequivalence Study of ADC118 Tablets in Healthy Chinese Volunteers Under Fasting Conditions
This clinical trial aims to evaluate the bioequivalence of a single oral dose of the test drug ADC118 tablets compared with the reference drugs (ACC017 tablets and emtricitabine/tenofovir alafenamide fumarate tablets [II]) under…
- Trial name
- NCT07753902
- Testing
- ACC118-Test, Reference
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Jiangsu Aidea Pharmaceutical Group Co., Ltd.
Healthy
Clinical Study to Assess the Effects of Prebiotic and Probiotic Supplement
Randomized, Crossover, Double-Blind, Placebo-Controlled, Single-Center Clinical Study with Daily Food Log, Stool Samples, Blood Draws, and Validated Questionnaires (GSRS, Bristol stool chart, and DQLQ) with Oral Dietary Supplement
- Trial name
- NCT06794619
- Testing
- Dietary Supplement with actives
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Olly, PBC
Human Experimentation
Study to Compare Gastric Inhibition of Two Proton Pump Inhibitors (CL2008-18)(P07815)(COMPLETED)
This study will determine differences between Proton Pump Inhibitors (PPI) formulations relative to their effects on gastric acidity.
- Trial name
- NCT01005719
- Testing
- Zegerid, Prevacid®
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Bayer
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.