Clinical trials: sponsored by Alcon Research
Dry Eye
An Evaluation of the Daytime Use of an Investigational Lubricant Eye Drop
The purpose of this study is to describe the subjective assessments of an investigational lubricant eye drop.
- Trial name
- NCT01139372
- Testing
- FID 115958D (Lubricant Eye Drop)
- Volunteers
- 96 people
- Sponsor
- Alcon Research
Dry Eye
Evaluation of Extended Tear Film Break Up Time (TFBUT) With an Ocular Emulsion
The primary objective of this investigation will be to quantify the increase in tear film break-up time (TFBUT) associated with the instillation of a single eyedrop of an Ocular Emulsion in dry eye sufferers.
- Trial name
- NCT01368198
- Testing
- Systane Balance Lubricating Eye Drops, OPTIVE™
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens Wear
Compliance and Contamination in Soft Contact Lens Wearers
The purpose of this study is to assess the lens and lens case microbial colonization associated with marketed care solutions used by experienced soft lens wearers.
- Trial name
- NCT01069237
- Testing
- OPTI-FREE RepleniSH, Clear Care
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract
To Compare the Ability of DiscoVisc® OVD to Protect the Corneal Endothelium and Maintain Anterior Chamber Space With Healon® and Amvisc® PLUS During Cataract Surgery.
The objective of the study is to assess how DisCoVisc Ophthalmic Viscosurgical Device (OVD) compares with Healon and Amvisc Plus in the protection of corneal endothelial cells, and the ability to maintain anterior chamber space…
- Trial name
- NCT00763360
- Testing
- DisCoVisc®, Healon, Amvisc Plus
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Alcon Research
Open-angle Glaucoma, Ocular Hypertension
Safety and Efficacy Study of DuoTrav APS Versus DuoTrav
The purpose of the study is to demonstrate that the IOP-lowering efficacy of DuoTrav APS, dosed once-daily in the morning, is non-inferior to that of DuoTrav, dosed once-daily in the morning.
- Trial name
- NCT00862472
- Testing
- DuoTrav APS, DuoTrav
- Sponsor
- Alcon Research
Cataract
Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
The purpose of this study is to evaluate the effect that placement and power of the AcrySof Toric has on post-operative visual acuity and spectacle independence for distance vision.
- Trial name
- NCT00760487
- Testing
- AcrySof Toric IOL
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Myopia
Evaluation of Daily Disposable Lenses With Multi-Purpose Solution (MPS)
The purpose of this study is to evaluate daily disposable lenses inserted out of the blister package versus daily disposable lenses inserted after a pre-soak in Multi-purpose solution FID 107027.
- Trial name
- NCT00733291
- Testing
- Nelfilcon A contact lens, Etafilcon A contact lens, FID 107027 solution
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Alcon Research
Cataract
Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1
The objective of this study is to prospectively evaluate the visual parameters in a series of patients after phacoemulsification cataract surgery in a series of patients bilaterally implanted with the AcrySof® ReSTOR® Aspheric…
- Trial name
- NCT00710931
- Testing
- AcrySof ReSTOR Aspheric IOL model SN6AD1
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Bacterial Conjunctivitis
Safety and Efficacy of AL-15469A 0.5% / AL-6515 0.3% Ophthalmic Suspension for Treatment of Bacterial Conjunctivitis
To assess safety and efficacy of AL-15469A 0.5% /AL-6515 0.3% Ophthalmic Suspension for treatment of bacterial conjunctivitis
- Trial name
- NCT01238783
- Testing
- AL-15469A 0.5% and AL-6515 0.3% Ophthalmic Suspension, AL-15469A 0.5%, AL-6515 0.3%
- Sponsor
- Alcon Research
Cataract
Visual Function With Contralateral AcrySof® ReSTOR® Aspheric SN6AD1 and SN6AD3
The objective of this study is to prospectively evaluate the visual parameters in a series of patients after phacoemulsification cataract surgery in a series of patients bilaterally implanted with the AcrySof® ReSTOR® Aspheric…
- Trial name
- NCT00710905
- Testing
- AcrySof ReSTOR Aspheric IOL models SN6AD1 and SN6AD3
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with the AcrySof® IQ ReSTOR® +3 versus those bilaterally implanted with the…
- Trial name
- NCT01166971
- Testing
- ReSTOR +3, Tecnis MF
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- Alcon Research
Glaucoma, Open-angle, Ocular Hypertension
A Long-term Safety Study of Once-daily Travatan
Long term safety study of TRAVATAN in patients with Open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00051168
- Testing
- Travatan
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- Alcon Research
Cataract
Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with Presbyopia-Correcting Intraocular Lenses (IOLs).
- Trial name
- NCT00963560
- Testing
- ReSTOR +3, Crystalens HD, Crystalens AO
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Alcon Research
Open-angle Glaucoma (OAG), Ocular Hypertension
Travoprost Five Day Posology Study
The purpose of this study is to determine the safety and efficacy of three concentrations of travoprost ophthalmic solution (Groups A, B and C) administered eight times daily.
- Trial name
- NCT01114893
- Testing
- Travoprost 0.004%, Travoprost Vehicle, Travoprost (Groups A, B and C)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Vasomotor Rhinitis
Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis
The purpose of this study is to examine safety and efficacy of Patanase and Astelin in treating the symptoms of non-allergic vasomotor rhinitis (VMR).
- Trial name
- NCT00979615
- Testing
- Olopatadine HCL (Patanase) Nasal Spray, 0.6%, Azelastine HCl (Astelin) Nasal Spray, 137 mcg
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Cataract
Visual Function and Patient Satisfaction After Bilateral Implantation of AcrySof Natural ReSTOR (Model SN60D3) or AcrySof Natural Monofocal (Model SN60AT)
The purpose of the study is: to compare visual parameters (Subjective refraction and Visual Acuity (VA)) and safety (tilt, decentration and posterior chamber opacification (PCO)) in a prospective series of 40 patients after…
- Trial name
- NCT00759668
- Testing
- Acrysof Natural ReSTOR SN60D3, Acrysof Natural Monofocal SN60AT
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Cataract
Posterior Capsule Opacification (PCO) Evaluation of the AcrySof SN60AT Lens vs. SN60WF Lens
To assess posterior capsule opacification (PCO) in patients implanted with either the AcrySof SN60AT lens or the AcrySof SN60WF lens.
- Trial name
- NCT00762021
- Testing
- SN60AT, SN60WF
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Cataract
ReSTOR Natural +3.0D Study In Japan
The objective of this study is to evaluate safety and effectiveness of ACRYSOF Multifocal Single-piece Intraocular Lens (IOL) Model SN6AD1 when implanted to replace the natural lens following cataract removal.
- Trial name
- NCT00758576
- Testing
- ACRYSOF Multifocal Single-piece Intraocular Lens (IOL) Model SN6AD1
- Where
- Japan
- Volunteers
- 64 people
- Sponsor
- Alcon Research
Cataract
Visual Performance of Bilateral AcrySof ReSTOR Aspheric +4
Determine the clinical visual outcomes following bilateral implantation of the AcrySof ReSTOR Aspheric Intraocular Lens (IOL) and to demonstrate what percentage of the subjects obtain spectacle freedom.
- Trial name
- NCT01215045
- Testing
- AcrySof ReSTOR Aspheric +4
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract Extraction, Corneal Astigmatism
Assessment of Visual Performance in Patients With Low Levels of Astigmatism
To assess visual performance in patients with low levels (0.5-0.75 Diopters) of corneal astigmatism.
- Trial name
- NCT00842231
- Testing
- Visual performance measures
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research