Clinical trials: sponsored by Alcon Research
Visual Acuity
Clinical Assessment of Visual Function With the Acrysof ReSTOR Multifocal IOL
The purpose of this study is to assess uniocular and binocular unaided distance, intermediate, and near VA; contrast sensitivity, accommodation amplitude, stereopsis, glare testing, ocular aberrations and the clinical…
- Trial name
- NCT00759096
- Testing
- RESTOR IOL Model SA60D3
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Intraocular Pressure
Azopt (Brinzolamide 1.0%) Plus Travatan (Travoprost 0.004%) in Treating Patients With Chronic Angle-Closure Glaucoma (CACG)
To evaluate the IOP (Intraocular Pressure) lowering efficacy and safety of Brinzolamide 1.0% (Azopt), dosed twice daily as adjunctive therapy in patients treated with Travoprost 0.004% (Travatan) once daily.
- Trial name
- NCT00758342
- Testing
- Travoprost 0.004% + Brinzolamide 1.0%, Travoprost 0.004% + Tears Natural
- Volunteers
- 37 people
- Sponsor
- Alcon Research
Astigmatism, Ametropia
Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses
The primary purpose of this study is to demonstrate noninferiority in the visual acuity at distance when wearing PRECISION1™ for Astigmatism (P1fA) soft contact lenses compared to another commercially available, soft toric…
- Conditions
- Astigmatism, Ametropia, Myopia
- Trial name
- NCT05483127
- Testing
- Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
- Where
- 11 sites in United States
- Volunteers
- 153 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs
This is a prospective, multicenter, post-approval active surveillance study. The purpose of this study is to report the rate of post-surgical intraocular inflammation (based upon a specified case definition) reported within a…
- Conditions
- Aphakia, Presbyopia, Astigmatism
- Trial name
- NCT03733730
- Testing
- ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL
- Where
- 38 sites in United States, Puerto Rico
- Volunteers
- 2,449 people
- Sponsor
- Alcon Research
Aphakia, Astigmatism
Clareon IOL Retrospective Data Collection
The purpose of this study is to provide real world evidence (RWE) on the performance of the Clareon ultraviolet absorbing (UVA) intraocular lenses (IOLs) to support the overall body of evidence on the Clareon IOL family.
- Trial name
- NCT05796674
- Testing
- Clareon UVA IOL, WaveTec Optiwave Refractive Analysis (ORA) System, Cataract surgery
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- Alcon Research
Dry Eye
Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers
The purpose of this study is to evaluate the ocular comfort of 3 ocular lubricants and a comparator.
- Trial name
- NCT05741216
- Testing
- OTF Ocular Lubricant, Ocular Lubricant
- Where
- 3 sites in Australia, Canada
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Dry Eye Disease
Evaluation of Safety and Tolerability of Investigational Ocular Lubricants
The purpose of this study is to evaluate investigational ocular lubricants for their safety and tolerability on subjects with mild to moderate dry eye disease.
- Trial name
- NCT05888519
- Testing
- FID123300 ocular lubricant, FID123301 ocular lubricant, FID122505 ocular lubricant
- Where
- 3 sites in Australia
- Volunteers
- 47 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population
The primary objective of this clinical study is to assess the clinical performance of the PanOptix IOL in a Chinese population.
- Trial name
- NCT04755231
- Testing
- AcrySof IQ PanOptix Presbyopia Correcting IOL, Cataract surgery
- Where
- 9 sites in China
- Volunteers
- 181 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05431478
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 68 people
- Sponsor
- Alcon Research
Presbyopia
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The primary objective of this study is to demonstrate noninferiority in visual acuity at distance when wearing the test contact lenses (LID210464) compared to the control contact lenses (AOHG MF) after 30 days of wear.
- Trial name
- NCT05338333
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
- Where
- 8 sites in United States
- Volunteers
- 101 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Real-World Study of Vivity Intraocular Lenses (IOLs)
The primary objective of this clinical study is to assess the clinical performance of the AcrySof IQ Vivity Extended Vision IOL in a Chinese population.
- Trial name
- NCT04800016
- Testing
- AcrySof IQ Vivity Extended Vision IOL, Cataract surgery
- Where
- China
- Sponsor
- Alcon Research
Refractive Errors, Myopia
Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear
The purpose of this clinical study is to evaluate the on-eye performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn continuously for up to 1 week.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT04403542
- Testing
- Lehfilcon A contact lens, Comfilcon A contact lens
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Cataract, Aphakia
Post-Market Clinical Investigation of the Clareon® IOL
The primary purpose of this study is to evaluate the long-term (3 years) visual acuity and adverse event outcomes for the Clareon® Intraocular Lens (IOL).
- Trial name
- NCT03316885
- Testing
- Clareon® IOL, Cataract Surgery
- Where
- 19 sites in Australia, France and 5 more
- Volunteers
- 245 people
- Sponsor
- Alcon Research
Bullous Keratopathy, Corneal Erosion
AONDA Therapeutic Indication Study I
This study will be used to support assessment of AIR OPTIX® NIGHT \& DAY® AQUA (AONDA) Soft Contact Lenses' safety and performance in accordance with updated European Union Medical Device Regulation (EU MDR) requirements.
- Conditions
- Bullous Keratopathy, Corneal Erosion, Entropion, Corneal Edema
- Trial name
- NCT05891106
- Testing
- Lotrafilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Dry Eye
Evaluation of Safety and Tolerability of Ocular Lubricants
The purpose of this study is to evaluate the safety profile of test formulations for an artificial tear product versus a comparator product.
- Trial name
- NCT05573360
- Testing
- NGF5-A test formulation, NGF4-B test formulation, NGF6-B test formulation
- Where
- 2 sites in Australia
- Volunteers
- 41 people
- Sponsor
- Alcon Research
Refractive Errors, Astigmatism
Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens
The purpose of this clinical study is to assess the clinical performance of an investigational toric soft contact lens compared to a commercially available toric contact lens in a crossover dispense trial when worn in a daily…
- Trial name
- NCT05211739
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Assessment of Two Daily Wear Reusable Soft Silicone Hydrogel Contact Lenses
The overall objective of this clinical study is to describe the clinical performance of the TOTAL30® soft contact lens compared to the ACUVUE® OASYS® with HYDRACLEAR PLUS (AOHP) soft contact lens in a daily wear modality.
- Trial name
- NCT05056987
- Testing
- Lehfilcon A contact lenses, Senofilcon A contact lenses, AOSEPT PLUS with HydraGlyde
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Refractive Ametropia
Assessment of an Investigational Frequent Replacement Silicone Hydrogel Lens
The purpose of this clinical trial is to evaluate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in an extended wear modality.
- Trial name
- NCT04085328
- Testing
- LID015385 soft contact lenses, Comfilcon A soft contact lenses
- Where
- 42 sites in United States
- Volunteers
- 675 people
- Sponsor
- Alcon Research
Refractive Ametropia, Hyperopia
Air Optix Night and Day Aqua (AONDA) Retrospective Study 1
The purpose of this study is to assess long term performance and safety of AONDA in a real world setting when worn as daily wear or continuous wear for vision correction.
- Conditions
- Refractive Ametropia, Hyperopia, Myopia
- Trial name
- NCT05790928
- Testing
- Lotrafilcon A spherical contact lenses
- Where
- 4 sites in United States
- Volunteers
- 108 people
- Sponsor
- Alcon Research
Astigmatism, Refractive Errors
Clinical Comparison of Toric Contact Lenses Fit Characteristics
The purpose of this study is to compare the fit characteristics between four Alcon commercially available toric contact lenses.
- Trial name
- NCT05805345
- Testing
- Delefilcon A toric soft contact lens, Lehfilcon A toric soft contact lens, Lotrafilcon B toric soft contact lens
- Where
- 7 sites in United States
- Sponsor
- Alcon Research