Clinical trials: sponsored by Oregon Health and Science University
Healthy
The Combination Effect of Citicoline and Omega-3
The goal of this study is to determine the effects of Citicoline plus Omega-3 or Omega-3 alone versus placebo on attention in non-demented healthy older adults.
- Trial name
- NCT03444662
- Testing
- Citicoline and Omega-3 supplement, Omega-3 supplement
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kyowa Hakko Bio Co., Ltd.
Mild to Moderate Traumatic Brain Injury
PoNS Clinical Experience Program (TBI)
Brief Summary: Prospective, cohort, open-label study. The cohort consists of people who have a chronic balance dysfunction due to a mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT03881202
- Testing
- PoNS Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Helius Medical Inc
Parkinson Disease
Acute Effects of Preladenant (SCH 420814) on Dyskinesia and Parkinsonism in Levodopa Treated Participants (P05550)
This is a randomized, placebo-controlled, 3-period crossover, balanced, single-site, third party-blind study of preladenant (SCH 420814) in participants with Parkinson disease (PD) to be conducted in conformance with Good…
- Trial name
- NCT00845000
- Testing
- SCH 420814 10 mg, SCH 420814 100 mg, Levodopa
- Volunteers
- 12 people
- Sponsor
- Merck Sharp & Dohme LLC
Attention Deficit Hyperactivity Disorder
Neurophysiological Attention Test (NAT) for Objective Assessment of Adult ADHD
The purpose of this study is to refine a new assessment tool for Attention Deficit/Hyperactivity Disorder (ADHD) and then to test its validity (i.e. ability to discriminate between individuals with ADHD and healthy controls.
- Trial name
- NAT-II (NCT02756286)
- Testing
- NAT electroencephalography (EEG) test
- Where
- 3 sites in United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Think Now Incorporated
Behavioral and Psychiatric Symptoms of Dementia
Feru-guard for Behavioral Symptoms in Dementia
This is designed as a randomized, double-blind, placebo-controlled clinical trial with a 12 week intervention period. Seventy participants with a diagnosis of AD, vascular, and mixed dementia with at least 3 behavioral symptoms…
- Trial name
- NCT03451760
- Testing
- Feru-guard 100M
- Volunteers
- 70 people
- Sponsor
- Glovia Co., Ltd.
Leber Congenital Amaurosis
Phase 1/2 Safety and Efficacy Study of AAV-RPE65 Vector to Treat Leber Congenital Amaurosis
The purpose of the study is to evaluate the safety and efficacy of an adeno-associated virus vector expressing RPE65 in patients with Leber congenital amaurosis caused by mutations in the RPE65 gene. Funding Source - FDA OOPD
- Trial name
- NCT00749957
- Testing
- rAAV2-CB-hRPE65
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Beacon Therapeutics
Androgen-independent Prostate Cancer
Mitoxantrone ± Cetuximab 2nd Line Androgen Independent Prostate Cancer (AIPC)
To determine the time to progression produced by the combination of Novantrone (mitoxantrone) and Erbitux (cetuximab) versus Novantrone alone in metastatic AIPC patients previously treated with docetaxel-based chemotherapy.
- Trial name
- NCT00661492
- Testing
- cetuximab, Mitoxantrone
- Where
- 55 sites in United States
- Volunteers
- 115 people
- Sponsor
- US Oncology Research
Stroke, Cerebrovascular Accident
AMES Treatment of the Impaired Leg in Chronic Stroke Patients
The purpose of this protocol is to determine if individuals who had a stroke more than one year before entering the study and whose ankles remain substantially impaired are able to sense and move the affected leg better after…
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- AMES (NCT01378637)
- Testing
- AMES- Leg treatment
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- AMES Technology
Hernia
Large Abdominal Hernia Repair With SurgiMend 3.0
The rate of hernia recurrence at one year following repair of a large abdominal hernia with a biologic mesh is high, ranging from 30% to 100%, with a reported historic average rate of 40%.
- Trial name
- BRIDGE (NCT00892333)
- Where
- 8 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Integra LifeSciences Corporation
Left Ventricular Dysfunction, Right Ventricular Dysfunction
A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System
This study is to collect data and learn more about the Vscan Ultrasound Imaging System. It is an "observational" study with no additional procedures or intervention prescribed other than using the Vscan along with a routine…
- Conditions
- Left Ventricular Dysfunction, Right Ventricular Dysfunction, Pulmonary Hypertension, Heart Valve Diseases
- Trial name
- NCT01076296
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- GE Healthcare
Proximal Caries
Lesion Progression of Approximal Caries After Resin Infiltration
The aim of the planned in-vivo trial is to investigate the effectiveness of the caries infiltration technique for the repression of caries progression.
- Trial name
- NCT02191943
- Testing
- Duraphat, Icon approximal caries infiltration kit
- Where
- United States
- Sponsor
- DMG Dental Material Gesellschaft mbH