Clinical trials: Acetaminophen, completed
Acute Pain, Cancer Pain
Usefulness of Acetaminophen Associated With Strong Opioids for Acute Pain in Cancer Patients
Cancer pain is one of the most frequent and relevant symptoms in cancer patients and has a great impact on a patient's quality of life.
- Trial name
- NCT04779567
- Testing
- Acetaminophen
- Where
- Chile
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Musculoskeletal Injury
Synergistic Effect Of Parenteral Diclofenac And Paracetamol In The Pain Management Of Acute Limb Injuries
Acute limb injury is a common reason to visit an emergency department worldwide. Intense pain related to the injury is always a concern for an emergency physician and requires effective analgesia within the shortest possible…
- Trial name
- NCT04199572
- Testing
- Diclofenac and Paracetamol
- Where
- Qatar
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Fear
The Effects of Acetaminophen on Fear
This study investigates the effects of acetaminophen on behavioral, physiological, and self-report fear responses.
- Trial name
- NCT05396677
- Testing
- Acetaminophen
- Where
- Canada
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Pain, Postoperative, Analgesia
Pre-operative Analgesics for Postoperative Pain Relief After Dental Treatment
The aim of the study is to compare the efficacy of the pre-operative administration of Paracetamol and placebo in reducing postoperative pain after routine dental treatment in children.
- Trial name
- NCT02393339
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Healthy
An Open Label Pilot Study to Evaluate the Efficacy of Spanish Black Radish on the Induction of Phase I and Phase II Enzymes
This study will investigate the effect of Spanish Black Radish on phase I and phase II enzyme activity in healthy adult males. The primary objective is to determine the effect on phase I and phase II enzyme activity by measuring…
- Trial name
- 11SEHS (NCT02137590)
- Testing
- Spanish Black Radish product
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Postprandial Lipemia, Satiety
Emulsion Droplet Physical State on Postprandial Lipemia and Satiety
The purpose of this study is to compare the changes in blood lipids and feelings of satiety after consumption of oil-in-water emulsions in which the droplets are in either the liquid or solid (i.e. crystalline) states.
- Trial name
- NCT03515590
- Testing
- Emulsion with solid droplets, Emulsion with liquid droplets
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Physiotherapy
EMG at Performing ULTN 1 in Breast Cancer Patients
Upper limb neural mechanosensitivity is a painful disturbance that breast cancer patients often undergo following axillary surgery.
- Trial name
- NCT02599467
- Testing
- ULNT 1 and EMG recording
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Breech Presentation, Pregnancy
Remifentanil Versus Paracetamol for Pain Treatment External Cephalic Versions.
BACKGROUND: Between 3-4% of pregnancies carried to term, the fetuses are in breech presentation. The external version is a maneuver gynecological used to turn a breech in cephalic presentation.
- Trial name
- NCT01048398
- Testing
- remifentanil, paracetamol
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Overweight or Obesity
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-4729 Injection in Healthy Subjects
The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-4729 injection in healthy subjects.
- Trial name
- NCT06762600
- Testing
- HRS-4729 injection, HRS9531 injection, Acetaminophen
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Postoperative Pain
TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management
In this randomized, controlled, observer-blinded study we plan to evaluate pain relief after ultrasound-guided transversus abdominis plane (TAP) block using bupivacaine and wound infiltration using liposomal bupivacaine in…
- Trial name
- NCT02074709
- Testing
- Plain bupivacaine, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Healthy Subjects
Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol® Extend
This study will evaluate the pharmacokinetic profiles of experimental formulations of paracetamol.
- Trial name
- NCT01540721
- Testing
- Marketed paracetamol, Experimental paracetamol formulation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Multimodal Analgesia, Nonsteroidal Anti-inflammatory Drugs
NSAID vs. Narcotics
This will be a single-center, prospective observational study. The study will compare post-operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and Percocet…
- Trial name
- NCT02915055
- Testing
- Ibuprofen 600 mg, standard oxycodone/acetaminophen
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Acetaminophen Metabolism, Acetaminophen Poisoning
Effect on Acetaminophen Metabolism by Liquid Formulations
The purpose of this study is to determine whether excipients in the liquid formulation of acetaminophen prevent the formation of the toxic metabolites of acetaminophen.
- Conditions
- Acetaminophen Metabolism, Acetaminophen Poisoning, Drug Metabolism by Excipients
- Trial name
- NCT01246713
- Testing
- Acetaminophen liquid formulation, Acetaminophen solid formulation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Pre-emptive Analgesia in Different Psycho-emotional Status Patients
Pre-emptive Analgesia Effect in Different Psycho-emotional Status Patients During Lower Third Molar Surgical Extractions
To increase the effectiveness of pain control, it is recommended to use drugs before the pain onset, therefore the pre-emptive analgesia method is considered as a method, which allows decreasing the post-operative pain to…
- Trial name
- NCT04202224
- Testing
- Ibuprofen 400 mg and Acetaminophen 500 mg, Glucose, No drug
- Where
- Lithuania
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Opioid-Related Disorders
Abuse Potential of Intranasal VYCAVERT Tablets (Hydrocodone Bitartrate/Acetaminophen) in Recreational Opioid Users
To determine the relative abuse potential of VYCAVERT (hydrocodone bitartrate and acetaminophen) compared to GENERIC H/A (hydrocodone bitartrate and acetaminophen) when crushed and administered intranasally to non dependent…
- Trial name
- NCT01759446
- Testing
- Generic H/A taken first, Vycavert taken first, Generic H/A plus i taken first
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Acura Pharmaceuticals Inc.
To Control Pain After Third Molar Surgery
Comparative Analgesic Effects of Paracetamol/Codeine and Ibuprofen on Pain After Third Molar Surgery
To compare analgesic effects of preoperative administration of paracetamol 500 milligram plus codeine 30 milligram in single-tablet and effervescent formulation to ibuprofen 400 milligram, and placebo in the management of…
- Trial name
- NCT04730297
- Testing
- paracetamol 500 mg plus codeine 30 mg preoperative administration, ibuprofen 400 mg preoperative administration
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Gingival Recession
Clinical Evaluation of Single-stage Advanced Versus Rotated Flaps in the Treatment of Gingival Recessions
BACKGROUND: Several procedures have been reported for the surgical correction of gingival recession (GR), including the laterally positioned flap (LPF) and the coronally advanced flap (CAF), performed as single or two-stage…
- Trial name
- NCT02433912
- Testing
- Test - Laterally positioned flap, Control-Coronally positioned flap, 750 mg paracetamol
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Sickle Cell Anemia Crisis
Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises?
The purpose of this study is to determine whether IV acetaminophen can decrease the need for subsequent opioid administration in the acute management of sickle cell crisis pain in the pediatric emergency room.
- Trial name
- NCT03541980
- Testing
- Acetaminophen, Normal saline
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Newark Beth Israel Medical Center
Neonatal Male Circumcision
Enhanced Provision of Male Circumcision (MC) for HIV Prevention, Rakai, Uganda
Background: Medical male circumcision (MMC) for HIV prevention is a priority in 14 East and Southern African countries, and the long-term sustainability of MMC programs could best be achieved by early infant male circumcision…
- Trial name
- NCT02596282
- Testing
- Neonatal circumcision under topical anesthesia
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health