Clinical trials: Conventional therapy, completed
Parkinson Disease, Physical Activity
Physical Training Induced Plasticity of Motor Control Mechanisms in Parkinson's Disease Patients
There are experimental evidences of the important role of exercise in the PD, that induces similar effects to pharmacotherapy. So far, the mechanisms of the impact of these changes on the brain subcortical and cortical regions…
- Trial name
- NCT03753503
- Testing
- exercise, conventional physical therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Orthodontic Appliance Complication
Bond Failure of Two Types of Molar Buccal Tubes
This study looks at two new types of orthodontic brackets (metal squares of the brace) that have recently been released. Both types have been developed to allow the brackets to stick better to the tooth surface.
- Trial name
- NCT03476161
- Testing
- 3M Unitek Victory Series™ Superior Fit Buccal Tube with APC™ Flash-Free Adhesive. 4069-6103 / 4069-6114 / 4069-6203 / 4069-6214, 3M Unitek Victory Series™ Superior Fit Buccal Tube with APC™ II Adhesive. 3069-6103 / 3069-6114 / 3069-6203 / 3069-6214
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Polyneuropathies, Septic Shock
Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock
The aim of this study is to compare the effect of EMS and conventional physical therapy on strength and muscle mass and development in adult patients with severe sepsis and septic shock.
- Conditions
- Polyneuropathies, Septic Shock, Muscle Weakness
- Trial name
- NCT03765489
- Testing
- electrical muscle stimulation, conventional physical therapy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Chile
Chronic Periodontitis, Aggressive Periodontitis
Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis
The etiopathogenesis of periodontal disease results from complex interaction between infectious agents, mainly including bacteria, and host cellular and humoral immune responses.
- Conditions
- Chronic Periodontitis, Aggressive Periodontitis, Presence / Absence of EBV
- Trial name
- NCT01246596
- Testing
- dental root planing
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Spastic Cerebral Palsy
Cuevas Medek Exercises on Balance and Postural Control in Children With Spastic Cerebral Palsy
Cerebral palsy (CP) is a disorder characterized by abnormal tone, posture and movement and clinically classified based on the predominant motor syndrome-spastic hemiplegia, spastic diplegia, spastic quadriplegia, and…
- Trial name
- NCT05719623
- Testing
- CUEVAS MEDEK EXERCISES, BALANCE AND POSTURAL
- Where
- Pakistan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Heart Failure
Triple-site Biventricular Stimulation in the Optimization of CRT
Cardiac resynchronization is a recommended therapy for patients with advanced heart failure, under optimized medical treatment with reduced left ventricular ejection fraction and prolonged QRS, nevertheless, still 30% of the…
- Trial name
- TRIUMPH-CRT (NCT02350842)
- Testing
- triple-site biventricular pacing with peri-operative echo guidance, standard biventricular pacing
- Where
- 14 sites in France, Germany and 4 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- MicroPort CRM
White Spot Lesion
Preventive Therapy of White Spot Lesions Using Different Remineralizing Agents in Children From 3 to 12 Years Old
Compare by clinical observation, photographs and fluorescence the efficacy of sodium fluoride, silanofluoride and thiefenfluoride in treating white spots.
- Trial name
- NCT04705428
- Testing
- FLUORINE VARNISH
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Overweight, Obesity
NEAT - Prevention and Treatment of Overweight and Obesity.
This study will investigate the effect on Non-exercise Activity Thermogenesis (NEAT) when implementing active workstation at offices compared to conventional office work.
- Trial name
- InphactUm (NCT01997970)
- Testing
- Treadmill workstation, Health talk
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Umeå University
Altered Passive Eruption of Teeth, Guided Surgery
Computer Guided Esthetic Crown Lengthening
The objective of the present study was to evaluate the effectiveness of surgical esthetic crown lengthening using digitally assisted 3D printed surgical stents in management of excessive gingival display due to altered passive…
- Conditions
- Altered Passive Eruption of Teeth, Guided Surgery, Gummy Smile
- Trial name
- NCT05512312
- Testing
- Conventional Esthetic crown lengthening, Computer guided Esthetic crown lengthening
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Public Speaking, Social Fear
Exposure With Acceptance-Based Versus Habituation-Based Rationale for Public Speaking Anxiety
The purpose of this study is to compare two exposure-based behavioral group treatments for public speaking anxiety. Specifically, exposure within the context of psychological acceptance will be compared to exposure within a…
- Trial name
- NCT00842946
- Testing
- Exposure w/ Acceptance-Based Rationale, Exposure w/ Habituation-Based Rationale
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Drexel University
Healthy Older Adults
Effect of Dual Task in Aquatic Physical Therapy in Older Adults
Population ageing is associated with declines in motor and cognitive functions, which compromise autonomy and increase the risk of falls and cognitive impairment.
- Trial name
- NCT07270094
- Testing
- Aquatic Dual-Task Training, Conventional Aquatic Exercise
- Where
- Portugal
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Leiria
Diplegia
Effect of Functional Training on Motor Performance
The functional strength training is mainly dealt with anti-gravity muscles and aiming at maximal carry over in day to day activities.
- Trial name
- NCT04723641
- Testing
- functional training exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Badr University
Spinal Cord Injury, Insulin Resistance
IR and Microvascular Blood Flow in SCI
Persons with spinal cord injury (SCI) are at an increased risk for metabolic disorders, including that of insulin resistance. As a result of neurological injury, they often have impaired mechanisms that regulate blood vessel…
- Trial name
- NCT02034331
- Testing
- Insulin iontophoresis, Acetylcholine Iontophoresis, Heat application
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Recurrent Corneal Erosions
Phototherapeutic Keratectomy (PTK) on Recurrent Corneal Erosions
To determine the ten-year visual results and outcome of excimer laser phototherapeutic keratectomy (PTK) for recurrent corneal erosions.
- Trial name
- PTK x CE (NCT01251692)
- Testing
- Surgery
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Gingival Recession, Mucogingival Surgery
Microsurgical Instruments and Magnification May Enhance Treatment Outcomes Of Laterally Moved, Coronally Advanced Flap in Miller Class III Isolated Recession Defects
The benefits of microsurgical approaches in periodontal therapy have been described. The main focus of this study is to determine if using microsurgical LMCAF technique would improve the outcomes of the therapy for the Miller…
- Trial name
- NCT02281071
- Testing
- laterally moved coronally advanced flap with microsurgical instruments and x2.5 loupe
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Students
Physical Therapy Students' Reflective Thinking With Narrative Photography in Heart Transplantation
Physical therapy students must learn about heart transplantation, and must be able to communicate with patients using empathy and moral sensitivity.
- Trial name
- NCT05800912
- Testing
- Narrative photography, Traditional learning
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Exercise Intervention
Resistance Training Effects on Gut Microbiome and Cardiometabolic Outcomes
The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.
- Trial name
- NCT04906525
- Testing
- Resistance training, Conventional physical activity guidelines
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Malocclusion, Pain
Anxiety, Pain, and Quality of Life in Orthodontic Treatment
This study was evaluated anxiety, pain, and oral health-related quality of life in individuals treated with conventional fixed appliances (Group A) and clear aligners (Group B) for moderate malocclusion during the initial phase…
- Conditions
- Malocclusion, Pain, Anxiety, Quality of Life
- Trial name
- NCT06133296
- Testing
- Conventional fixed treatment, Clear aligner treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Apical Periodontitis
Therapeutic Irrigation Procedures to Treat Apical Periodontitis
Apical periodontitis is a dental infection which develops around the root of a tooth and affects ~4-6% of the UK population. Current treatment strategies focus solely on removing bacteria from within the root canal space during…
- Trial name
- TIPTAP (NCT03987659)
- Testing
- Irrigation protocols that promote release of dECMs, Conventional Irrigation protocols
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Intrusive Memories of Traumatic Event(s)
A Brief Cognitive Task Intervention for NHS Staff Affected by COVID-19 Trauma (GAINS-2 Study)
Frontline healthcare staff are frequently exposed to traumatic events at work (e.g., witnessing patients die), amplified by the COVID-19 pandemic.
- Trial name
- GAINS-2 (NCT05616676)
- Testing
- Brief digital imagery-competing task, Brief digital music-listening task, Treatment As Usual
- Where
- United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- P1vital Products Limited