Clinical trials: Methylphenidate, completed
Attention Deficit Disorder With Hyperactivity, Dental Caries
Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD)
To evaluate the dental status of children using ritalin and suffering from ADHA in comparison to healthy children.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Dental Caries, Dental Occlusion, Traumatic
- Trial name
- NCT00328224
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Naltrexone, Methylphenidate Abuse
Study for Naltrexone on the Abuse Potential of Methylphenidate
The current abuse liability study aims to assess the potential for co-administration of naltrexone (NTX) to reduce the abuse potential of methylphenidate (MPH).
- Trial name
- NCT03769064
- Testing
- Methylphenidate 60 mg, Treatment Phase Sequence 4213, Treatment Phase Sequence 2134
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Avekshan LLC
Attention Deficit Hyperactivity Disorder
Brain Dopamine Function in Adults With ADHD
The purpose of the study is to investigate the functional state of dopamine cells and the dopamine transporter in ADHD subjects and controls to assess the effects of chronic methylphenidate treatment on dopamine cell function and…
- Trial name
- Brookhaven (NCT00580814)
- Testing
- Experimental: methylphenidate treatment
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Attention Deficit Hyperactivity Disorder
The Neuroprotective Effects of Methylphenidate and Atomoxetine in Children With ADHD: A Lipidomic Study
1. To identify the difference in the lipidomic profiles between ADHD and controls; 2. To examine the effects of methylphenidate and atomoxetine on the lipidomic profiles in ADHD, and the relationship between medication-related…
- Trial name
- NCT03936491
- Testing
- Methylphenidate, Atomoxetine
- Where
- Taiwan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Alcohol Use Disorder, Attention Deficit Hyperactivity Disorder
Methylphenidate and Response to Alcohol Cues Pilot Study
The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate, also known as Ritalin, affects responses to alcohol cues.
- Trial name
- NCT06063200
- Testing
- Methylphenidate Pill
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy
A Drug Interaction Study of SPD503 and Concerta Administered Alone and In Combination in Normal Healthy Volunteers
This is a drug-drug interaction study; the purpose of this study is to examine the pharmacokinetics (levels of drug in the blood) of SPD503 (guanfacine hydrochloride) and Concerta (methylphenidate HCl) when given alone, and in…
- Trial name
- NCT00901576
- Testing
- SPD503, Concerta, SPD503 + Concerta
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shire
Healthy
The Role of Dopaminergic and Noradrenergic Neurotransmission in Value- and Salience-based Decision-Making
Approach versus avoidance decisions are at the centre of adaptive behaviour and survival. These decisions are thought to be guided by the value of the choice options, which are a function of the magnitude of predicted rewards and…
- Trial name
- NCT04371146
- Testing
- Methylphenidate, Reboxetine
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy, Attention Deficit Hyperactivity Disorder
Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))
The goal of this research is to understand the functioning of 'regulatory circuits' in the brain. We are also interested in how the medications methylphenidate and naltrexone affect these regulatory circuits.
- Trial name
- NMAS (NCT01993108)
- Testing
- Methylphenidate, Naltrexone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Attention Deficit-Hyperactivity Disorder
Influence of Stimulant Medication on Brain Processes for Decision Making in Attention Deficit Hyperactivity Disorder
The goal of this trial is to investigate the cognitive- and brain-mechanisms underlying decision making (DM) and learning in young adults with Attention-Deficit/Hyperactivity Disorder (ADHD) as well as the modulation of…
- Trial name
- NCT01831622
- Testing
- Ritalin
- Where
- 2 sites in Norway
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Mats Fredriksen
Healthy
Acute Effect of Three Neuroactive Drugs Measured by Magnetoencephalography (MEG), Electroencephalography (EEG) and the Synchronous Neural Interaction Test
This placebo-controlled crossover study is intended to measure the effect of three, common neuroactive medications on brain activity measured by magnetoencephalography (MEG) and electroencephalography (EEG).
- Trial name
- NCT00972985
- Testing
- modafinil, methylphenidate, lorazepam
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Orasi Medical, Inc.
Healthy, Substance-related Disorder
Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study
The purpose of this study is to investigate effects of methylphenidate, modafinil, and 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") on emotion-processing and cognitive performance using functional magnetic resonance…
- Conditions
- Healthy, Substance-related Disorder, Mood Disorder
- Trial name
- NCT01951508
- Testing
- Methylphenidate, Modafinil, MDMA
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy
Effects of Modafinil, Caffeine and Methylphenidate in Healthy Volunteers
In this study the investigators compare three stimulants to each other. The effects of these agents on cognitive performance (eg, attention and memory) and on the brain are being measured.
- Trial name
- MKM (NCT02071615)
- Testing
- Methylphenidate 20 mg tablet given once by mouth, modafinil 200mg tablet given once by mouth, caffein 200mg tablet given once by mouth
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
MPH Influence on Creativity
A Study on the Effect of Methylphenidate on Creativity of Healthy Adults
Creative cognition plays an important role in art, invention and innovation, as well as in everyday life and thus has a significant effect on society as a whole.
- Trial name
- NCT01683032
- Testing
- MPH
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Revised Medication Guide Formats
Consumer Understanding and Use of Medication Guides
The purpose of this study is to determine the potential efficacy of three revised Medication Guide layouts to increase consumers' comprehension
- Trial name
- NCT01731405
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Healthy Volunteers in Fed and Fasted State
Fed-Fast Crossover Study to Assess the Effect of Food With CTx-1301 in Healthy Subjects
The primary purpose of this study is to assess the effect of food on the rate and extent of absorption and the overall bioavailability of a single dose of CTx-1301 25 mg trimodal tablets in healthy adult volunteers.
- Trial name
- Fed-Fast (NCT04449250)
- Testing
- Dexmethylphenidate
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Cingulate Therapeutics
Stroke
Neurobiological Principles Applied to the Rehabilitation of Stroke Patients
The purpose of this study is to use (Transcranial Magnetic Stimulation) TMS or drugs to improve learning of movement skills and the adaptation processes in patients after stroke.
- Trial name
- NCT00715520
- Testing
- Transcranial Magnetic Stimulation (TMS), Carbidopa-Levodopa, Methylphenidate
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Emory University
Attention Deficit/Hyperactivity Disorder (ADHD)
Treatments for Fathers With ADHD and Their At-Risk Children (Fathers Too)
In contrast to mothers with Attention Deficit/Hyperactivity Disorder (ADHD), the impact of paternal ADHD in families and children with ADHD symptoms has not been studied, despite the prevalence of ADHD in males.
- Trial name
- NCT02675400
- Testing
- Vyvanse, Behavioral Parent Training, Methylphenidate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Motivation, Apathy
Motivation and Methylphenidate
The purpose of this study is to evaluate the impact of methylphenidate, a mixed dopaminergic and noradrenergic agent, onto the different components of motivation: decision-making, effort allocation and instrumental learning.
- Conditions
- Motivation, Apathy, Impulsive Behavior
- Trial name
- MBB_MPH (NCT03190681)
- Testing
- Ritalin (methylphenidate)10Mg Tablet
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Healthy
Effects of Commonly Used Medications on Mood and Choice
This non-treatment study will examine how commonly used prescription or over-the-counter medications may influence mood and medication preference.
- Trial name
- NCT03652740
- Testing
- Methylphenidate, Nicotine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy Volunteers
A PET Study Examining Pharmacokinetics and Dopamine Transporter Receptor Occupancy Of Two Long-Acting Formulations of Methylphenidate in Adults
The specific aim of this study is to document the pharmacokinetics of dopamine transporter DAT receptor occupancy of OROS MPH and Metadate CD using PET scanning with C-11 Altropane as the ligand.
- Trial name
- NCT00301639
- Testing
- OROS methylphenidate hydrochloride, methylphenidate hydrochloride
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital