Clinical trials: Acetaminophen, completed
Renal Colic, Urinary Calculi
Efficacy Study of Different Analgesic Options in Kidney Stone Pain Management
Abdominal pain is one of the most common presentations to an emergency department (ED). Among patients presenting with abdominal pain, a common diagnosis in the Middle East is renal colic (urolithiasis or Kidney stones).
- Trial name
- NCT02187614
- Testing
- Diclofenac, Morphine, Paracetamol
- Where
- Qatar
- Volunteers
- 1,645 people
- Sponsor
- Hamad Medical Corporation
Office Hysteroscopy
Efficacy of Oral Paracetamol Compared With Oral Ketoprofen for Pain Management in Office Hysteroscopy
Hysteroscopy is a procedure used to evaluate abnormalities within the uterus (intrauterine. Currently, hysteroscopy can be performed in an outpatient clinic setting according to established standards, known as office…
- Trial name
- NCT07315698
- Testing
- Ketoprofen 100mg, Paracetamol 1000 Mg Oral Tablet
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Mammoplasty, Postoperative Pain
Study of EXPAREL in Patients Undergoing Breast Augmentation
This is a Phase 4, prospective, open-label, non-randomized, sequential study with two treatment groups differing only in the technique used for EXPAREL administration (instillation or infiltration).
- Trial name
- NCT01582490
- Testing
- Instillation - EXPAREL, Infiltration - EXPAREL
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Hand Osteoarthritis
Crystalline Glucosamine Sulfate Therapy in Hand Osteoarthritis
The objective of this study is to retrospectively evaluate the symptomatic effects of crystalline glucosamine sulfate (GS), prescribed for the actually approved indication of knee OA, in addition to conventional therapy, in…
- Trial name
- NCT03911570
- Testing
- Glucosamine Sulfate
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- University of Siena
Pain, Fever
Safety and Pharmacokinetic (PK) Study of Intravenous (IV) Acetaminophen Administration in Pediatric Inpatients
We are doing this study to find out what happens to acetaminophen in the body after it is given to children through the vein. Children's bodies may handle drugs differently than adults.
- Trial name
- NCT00493246
- Testing
- IV Acetaminophen
- Where
- 5 sites in United States
- Volunteers
- 75 people
- Sponsor
- Mallinckrodt
Hypertension
Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia
Hypertensive disorders of pregnancy are a major cause of maternal mortality and morbidity, especially in developing countries. Postpartum hypertension can be related to persistence of gestational hypertension, preeclampsia, or…
- Trial name
- NCT01988298
- Testing
- Ibuprofen, Acetaminophen
- Where
- Panama
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Healthy Subjects
Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol®
A single dose pharmacokinetic study investigating two paracetamol formulations
- Trial name
- NCT01540734
- Testing
- Marketed paracetamol, Experimental paracetamol formulation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Liver Transplant Recipient, Living Donor (of the Respective Liver Transplant Recipient)
Donor Alloantigen Reactive Tregs (darTregs) for Calcineurin Inhibitor (CNI) Reduction
This research study is for liver transplant recipients and their respective living donors. The purpose of this study is: 1. To see if it is safe for liver recipients to receive one dose of donor reactive T regulatory cells…
- Trial name
- ARTEMIS (NCT02474199)
- Testing
- darTregs, Acetaminophen, Diphenhydramine
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lumbar Spine Disc Herniation, Lumbar Radiculopathy
Surgery Versus Standardized Non-operative Care for the Treatment of Lumbar Disc Herniations: A Canadian Trial
The objective of this study is to determine if surgery is superior to non-operative care for sciatica caused by a lumbar disc herniation.
- Trial name
- NCT01335646
- Testing
- Lumbar Microdiscectomy, Physiotherapy, Epidural injections, Education, Pain Medications, Anti-inflammatories
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- The London Spine Centre
Acetaminophen Toxicity
Treatment of Acetaminophen Toxicity With N-acetylcysteine
Retrospective chart review of patients who received N-acetylcysteine for APAP toxicity to assess length of oral vs IV treatment and overall healthcare costs.
- Trial name
- NCT00725179
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Akron Children's Hospital
Covid19
Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic
Background: Up-to-date, there is no recognized effective treatment or vaccine for the treatment of coronavirus disease (COVID-19) that emphasize urgency around distinctive effective therapies.
- Trial name
- NCT04668469
- Testing
- Ivermectin, Hydroxychloroquine, personal protective Measures
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Benha University
Idiopathic Thrombocytopenic Purpura
A Study Evaluating the Addition of MabThera (Rituximab) to Standard Treatment in Patients With Idiopathic Thrombocytopenic Purpura (ITP)
This study will compare the efficacy, safety, and pharmacokinetics of standard treatment versus standard treatment plus MabThera in patients with ITP.
- Trial name
- NCT00770562
- Testing
- rituximab, Dexamethasone
- Where
- 22 sites in Italy
- Volunteers
- 103 people
- Sponsor
- Hoffmann-La Roche
Rhabdomyosarcoma
TAA-Specific CTLS for Solid Tumors (TACTASOM)
This is a clinical trial for patients with a solid tumor which has come back, or may come back, or has not gone away after treatment, including the standard treatment we know for these diseases.
- Trial name
- NCT02239861
- Testing
- TAA-Specific CTLs
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Baylor College of Medicine
Tendinopathy
Can Amino Acid Supplementation Augment the Anabolic Response in Tendon After Exercise
The goal of this study is to determine if an oral provision of amino acids will enhance exercise-induced increases in markers of Achilles tendon collagen production.
- Trial name
- NCT04067479
- Testing
- Amino Acids
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Purdue University
Low Back Pain
IV Paracetamol, Dexketoprofen or Morphine for the Treatment of Low Back Pain
This randomized, controlled trial evaluates the analgesic efficacy and safety of intravenous single-dose paracetamol, dexketoprofen and morphine for the treatment of low back pain.
- Trial name
- NCT01422291
- Testing
- paracetamol, morphine, Dexketoprofen
- Volunteers
- 120 people
- Sponsor
- Pamukkale University
Obesity
Prospective, Double Blind, Placebo Control, Bariatric IV Ace
The purpose of this study is to determine if the administration of acetaminophen given intravenously (through an IV) beginning during surgery and then for 3 additional doses during the first 24 hours post-operatively will reduce…
- Trial name
- Bariatricace (NCT02452320)
- Testing
- intravenous acetaminophen
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Weill Medical College of Cornell University
Patent Ductus Arteriosus, Extreme Prematurity
Canadian National PDA Treatment Study
Patent ductus arteriosus (PDA) is the most common cardiovascular problem that develops in preterm infants. Persistent PDA may result in higher rates of death, chronic lung disease (CLD), pulmonary hemorrhage, necrotizing…
- Trial name
- CANRxPDA (NCT04347720)
- Testing
- Indomethacin, Ibuprofen, Acetaminophen
- Where
- 22 sites in Canada
- Volunteers
- 1,663 people
- Sponsor
- IWK Health Centre
Postoperative Pain
Intravenous Acetaminophen in Craniotomy
The purpose of this study is to assess the use of intravenous Acetaminophen (OFIRMEV) as an effective adjunct therapeutic agent in patients undergoing craniotomy.
- Trial name
- NCT01598701
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain, Gynecologic Disease
Additive Effect of Intravenous Acetaminophen on Postoperative Pain Control
This study aimed to evaluate the additive effect of acetaminophen on postoperative pain control in patients receiving nefopam and fentanyl-based patient-controlled analgesia.
- Trial name
- NCT03644147
- Testing
- Acetaminophen
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Shoulder Lesions
Fentanyl vs Dexmedetomidine for Arthriscopic Shoulder Intervention in Elderly.
Arthroscopic shoulder surgeries are commonly used as a minimally invasive surgery for shoulder diseases. however, it causes moderate-to-severe pain and needs stabilization of hemodynamics, without compromising the patient, to the…
- Trial name
- NCT05577117
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
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